標題: Titlebook: Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials; Meinhard Kieser Book 2020 The Editor(s) (if appl [打印本頁] 作者: metabolism 時間: 2025-3-21 16:09
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書目名稱Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials讀者反饋
書目名稱Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials讀者反饋學科排名
作者: OUTRE 時間: 2025-3-21 20:49
2366-8695 e size calculation and recalculation in clinical trials, tak.This book provides an extensive overview of the principles and methods of sample size calculation and recalculation in clinical trials. Appropriate calculation of the required sample size is crucial for the success of clinical trials. At t作者: peptic-ulcer 時間: 2025-3-22 04:08 作者: analogous 時間: 2025-3-22 06:10 作者: 蠟燭 時間: 2025-3-22 12:39 作者: 猛烈責罵 時間: 2025-3-22 16:02
Comparison of Two Groups for Binary Outcomes and Test for Difference or Superiority odds ratio. For these measures and two-group comparisons with assessment of difference or superiority, sample size calculation methods are given for asymptotic tests (chi-square test, logistic regression) as well as for the exact unconditional Fisher-Boschloo test.作者: Archipelago 時間: 2025-3-22 19:02
Comparison of Two Groups for Normally Distributed Outcomes and Test for Equivalence irrelevant amount. In this chapter, methods for sample size calculation are described when applying the “two one-sided tests procedure” for equivalence assessment. The situation of normally distributed outcomes and the cases that the treatment effect is expressed in terms of the difference or ratio of means, respectively, are considered.作者: 悲痛 時間: 2025-3-22 21:59 作者: 確定的事 時間: 2025-3-23 03:39 作者: 灰心喪氣 時間: 2025-3-23 08:33 作者: 秘密會議 時間: 2025-3-23 10:52
Comparison of Three Groups in the Gold Standard Non-Inferiority Designhes are distinguished: the net effect approach, where assessment is based on the pairwise comparisons between placebo, the experimental treatment, and the reference, and the fraction effect approach, where non-inferiority assessment is based on effect retention of the experimental treatment versus the reference relative to placebo.作者: Intercept 時間: 2025-3-23 14:42 作者: Cuisine 時間: 2025-3-23 20:37 作者: Arthropathy 時間: 2025-3-23 22:42 作者: Anticlimax 時間: 2025-3-24 04:14
Springer Series in Pharmaceutical Statisticshttp://image.papertrans.cn/m/image/632206.jpg作者: 肌肉 時間: 2025-3-24 09:36 作者: 武器 時間: 2025-3-24 11:55
Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials978-3-030-49528-2Series ISSN 2366-8695 Series E-ISSN 2366-8709 作者: 出來 時間: 2025-3-24 16:08
Comparison of More Than Two Groups and Test for DifferenceIn many clinical trials, more than two interventions are investigated simultaneously thus enabling a head-to-head comparison of different therapeutic options. This chapter provides sample size calculation methods for this situation and the cases of normally distributed, continuous, binary, and time-to-event outcomes.作者: 侵蝕 時間: 2025-3-24 20:26 作者: inculpate 時間: 2025-3-25 02:24
Statistical Test and Sample Size Calculatione roles of type I and type II error rates, respectively. Based on these explanations, the general principle of sample size calculation is derived. The basic inequality to be resolved when determining the required sample is given in its general formulation as well as for the special case of normally distributed test statistics.作者: WAIL 時間: 2025-3-25 06:15
Comparison of Two Groups for Continuous and Ordered Categorical Outcomes and Test for Difference or n. The situations of two groups with continuous or ordered categorical data are considered. For the latter, the cases that the assumption of proportional odds holds true or cannot be assumed to hold true, respectively, are distinguished.作者: 油膏 時間: 2025-3-25 09:33
Simulation-Based Sample Size Calculationnging or is not possible at all. In such situations, simulations are a useful and flexible tool for determining the sample size. In this chapter, a general simulation-based approach for a sample size calculation is described and hints for practical implementation are given.作者: SEVER 時間: 2025-3-25 12:21 作者: Flavouring 時間: 2025-3-25 19:38 作者: insipid 時間: 2025-3-25 21:06
Meinhard Kiesert a variable magnitude output voltage in tune with the change in the modulation index. The regulated output voltage over a range of operating loads and the sinusoidal shape of the supply current substantiate the merits of the strategy and claim its applicability in the utility world.作者: Budget 時間: 2025-3-26 01:39
Meinhard Kieserfying the accessibility measures adopted in the cities of Braga and Guimar?es, in the Northern Region of Portugal, through issues related to the specific training of employees, the use of new technologies as a competitive advantage, the concern with presenting information in various formats and the 作者: 打擊 時間: 2025-3-26 06:08
ctors such as position of responsibility, seasonality of the job, the training provided, but also the level of quality of the hotel’s services. The research was pilot and intended to indicate the directions and fields for a larger future research on the specific questions. The survey was conducted i作者: myalgia 時間: 2025-3-26 08:59
Meinhard Kiesero analyze the influence of digitization factors on human capital. The digitization of the tourism industry makes businesses in this field more flexible, adapted to modern conditions, and more competitive in a dynamic “digital world.” The result of this research is to provide new digital opportunitie作者: DRILL 時間: 2025-3-26 15:48 作者: 鴿子 時間: 2025-3-26 18:05 作者: FLIC 時間: 2025-3-27 00:48
Meinhard Kiesermongst the admixtures and thus the soil improvement of the various woodash proportions. The woodash-soil admixture that gave the best improvement quality was further mixed with 2%, 4%, 6% and 8% lime and PI, LS, FSI and UCS of each woodash-soil-lime admixture also determined to ascertain the amount 作者: 擴大 時間: 2025-3-27 02:27
Meinhard Kieserrements is required. The proposed model minimizes the round-off errors and eliminates the large number of calculations associated with numerical techniques. The basis of the proposed method is the development of eigenvalues and eigenvectors associated with time-rate of settlement. The proposed expli作者: enlist 時間: 2025-3-27 05:44 作者: Guaff豪情痛飲 時間: 2025-3-27 12:01
Meinhard Kieserons (i.e., pump operation, tank levels, pressure-reducing valve settings), and an adjustment of the input data for the model to improve the agreement between the observed and predicted values. In practice, given a set or sets of measured state variables, engineers apply trial and error techniques, u作者: CANE 時間: 2025-3-27 17:33
Meinhard Kieserons (i.e., pump operation, tank levels, pressure-reducing valve settings), and an adjustment of the input data for the model to improve the agreement between the observed and predicted values. In practice, given a set or sets of measured state variables, engineers apply trial and error techniques, u作者: 混合,攙雜 時間: 2025-3-27 21:44 作者: 閑聊 時間: 2025-3-27 22:09
Meinhard Kieserhough the exact rTMS mechanisms of action are not completely understood, rTMS seems to cause its beneficial effects through changes in neuroplasticity. Devices and protocols for rTMS are still evolving, becoming more efficient over time. There are still some challenges to be addressed, including fur作者: creatine-kinase 時間: 2025-3-28 03:21 作者: Gorilla 時間: 2025-3-28 07:03 作者: 顛簸下上 時間: 2025-3-28 12:31
Meinhard Kieserven months of regular administration prior to eliciting a rational clinical effect. Owing to the strong evidence showing a relationship between neural plasticity, neurogenesis, and MDD, researchers have also looked at the possibility of using treatment modalities that target these processes in an at作者: 節(jié)省 時間: 2025-3-28 15:20
Meinhard Kieseraviour of beeswax oil systems corresponded to weak gels at this temperature. This was also reflected in an increase in the temperature at which the gel-sol transition occurred when the systems were heated. The transition took place at higher temperatures for the monoglyceride gels, which indicates t作者: peritonitis 時間: 2025-3-28 19:58 作者: 攤位 時間: 2025-3-28 23:53 作者: GIST 時間: 2025-3-29 03:11 作者: 玉米 時間: 2025-3-29 08:14
2366-8695 ics is discussed, including sample size calculation for multiple comparisons, safety assessment, and multi-regional trials. There is often some uncertainty about the assumptions to be made when calculating the 978-3-030-49530-5978-3-030-49528-2Series ISSN 2366-8695 Series E-ISSN 2366-8709 作者: 和藹 時間: 2025-3-29 13:26 作者: 仇恨 時間: 2025-3-29 19:29
sed the demand for portable energy storage devices. The energy storage devices have the potential to withstand the fear of fossil fuel scarcity along with controlling global warming. There are various energy storage devices like capacitors, fuel cells, supercapacitors, and batteries. Out of all thes作者: evanescent 時間: 2025-3-29 23:34
oil, and reduction of atmospheric carbon in carboniferous era. Change in solar brightness, solar activity, volcanic activities have resulted in the variation of solar radiations received on Earth. Such changes have led in change in the life dominating in the past and at present, geographical distrib作者: 慢慢流出 時間: 2025-3-30 02:20 作者: 流浪者 時間: 2025-3-30 06:44 作者: Constant 時間: 2025-3-30 10:06
y, which could not be met. In 2022, the year following the pandemic, 60,200 jobs, based on the organization charts of hotels in Greece, were not occupied due to shortage of staff. This paper presents the results of a research that aimed to discover the factors that lead to job satisfaction, of the h作者: 改正 時間: 2025-3-30 13:03 作者: Comedienne 時間: 2025-3-30 18:18
Meinhard Kieser By leveraging cutting-edge algorithms for optimal multicriteria dynamic route planning; indoor positioning and localization; and user experience assessment, OPTORER aims to create significant opportunities for exploitation and capitalization, initiating new markets and increasing the market share o作者: Somber 時間: 2025-3-30 22:10 作者: infelicitous 時間: 2025-3-31 02:22
Meinhard Kieserdustrial woodash to X-ray fluorescence (XRF) to determine its chemical composition while an expansive soil underlain by the Coniacian Awgu Group was subjected to X-ray diffraction (XRD) to determine the mineralogy of the soil. The plasticity index (PI), linear shrinkage (LS), free swell index (FSI)
