標(biāo)題: Titlebook: Metalloproteinases as Targets for Anti-Inflammatory Drugs; Kevin M. K. Bottomley,David Bradshaw,John S. Nixon Book 1999 Springer Basel AG [打印本頁(yè)] 作者: 字里行間 時(shí)間: 2025-3-21 19:29
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書目名稱Metalloproteinases as Targets for Anti-Inflammatory Drugs讀者反饋學(xué)科排名
作者: Schlemms-Canal 時(shí)間: 2025-3-21 21:13 作者: Collar 時(shí)間: 2025-3-22 00:49 作者: 反話 時(shí)間: 2025-3-22 07:04
,TNFα converting enzyme, of this molecule and gave insight into the signaling pathways that initiated TNFα transcription, the unique control of its translation and the TNF receptors that bind the secreted, 17 kDa molecule. These receptors reside on cells of nearly every tissue and, in turn, transduce the signals that result in changes in cell behavior.作者: 爵士樂 時(shí)間: 2025-3-22 10:37
Matrix metalloproteinases in neuro-inflammatory disease,vidence to show that MMPs are produced within the nervous system in several important diseases, notably multiple sclerosis, Guillain-Barré syndrome and stroke, and that inhibiting their activity may be of clinical benefit.作者: Scintillations 時(shí)間: 2025-3-22 16:20
Adhesion molecule sheddases,ic adhesion between adjacent epithelial cells is long-lived and serves to control the permeability of epithelial layers over days. In contrast, heterotypic adhesion between leucocytes and the blood vessel wall which regulate migration into tissues is short-lived, allowing leucocytes to accumulate within minutes (see below).作者: heckle 時(shí)間: 2025-3-22 17:13
Book 1999current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for those with an interest in inflammatory diseases. Thus it addresses both academic and industrial researchers.作者: 果仁 時(shí)間: 2025-3-22 23:36 作者: Blatant 時(shí)間: 2025-3-23 03:41
1422-7746 icular their participation in autoimmune diseases such as rheumatoid arthritis, reviewing the latest developments in metalloproteinase inhibitor design and the current status of clinical candidates. This volume is intended not only for those active in research into metalloproteinases but also for th作者: achlorhydria 時(shí)間: 2025-3-23 06:56 作者: BOOR 時(shí)間: 2025-3-23 12:38 作者: 頭盔 時(shí)間: 2025-3-23 15:53
Role of stromelysin-1 in cartilage metabolism,n-1 (SLN-1) is synthesized and secreted as an inactive zymogen [1]. Several proteinases activate this enzyme .however, the physiological activator has yet to be identified. The expression of SLN-1 is upregulated by pro-inflammatory cytokines such as interleukin 1 (IL-1) and tumor necrosis factor a (作者: Corroborate 時(shí)間: 2025-3-23 18:01
Matrix metalloproteinases in neuro-inflammatory disease,lammatory, infectious and traumatic disorders [.]. The presence of active MMPs in local excess over the levels of their natural inhibitors, the TIMPs, is thought to mediate pathology in many of these conditions, such as rheumatoid arthritis, inflammatory bowel disease and cancer [.]. It is only in t作者: Acumen 時(shí)間: 2025-3-24 00:41 作者: nonsensical 時(shí)間: 2025-3-24 05:41 作者: foppish 時(shí)間: 2025-3-24 07:18 作者: 脆弱么 時(shí)間: 2025-3-24 11:43
Adhesion molecule sheddases,air, tumorigenesis and immune responses [1,2]. Cells participate in a variety of adhesive interactions including homotypic adhesion in which the interacting cells are identical, heterotypic adhesion in which the interacting cells are dissimilar and direct adhesion to the extracellular matrix (ECM). 作者: 表示問 時(shí)間: 2025-3-24 16:12
,TNFα converting enzyme,thereby initiating complex signaling transduction pathways [1]. While TNFa has been studied since the earlier part of this century, the purification and cloning of this protein in 1985 [2 – 5] precipitated a decade of intensive research. These efforts demonstrated the cross-disciplinary significance作者: 發(fā)炎 時(shí)間: 2025-3-24 22:07 作者: FRET 時(shí)間: 2025-3-25 00:25
Neera Borkakotiy of these stereotypes and labels are informed by both historical and contemporary understandings of black women. Indeed, the persistent myth of the black woman as masculine, fiercely independent, hostile, aggressive, and domineering. works to frustrate the use of legal strategies generally availabl作者: Omniscient 時(shí)間: 2025-3-25 04:24
Jerauld S. Skotnicki,Jeremy I. Levin,Arie Zask,Loran M. Killarrican population for the purpose of preserving white power and privilege. During the first two and a half centuries of the black presence on the North American continent, the predominant mode of black oppression was enslavement. Blacks as a group were relegated to life outside of civil society; they作者: 消耗 時(shí)間: 2025-3-25 10:44 作者: Euphonious 時(shí)間: 2025-3-25 15:44
Andrew J.H. Gearing,Sally E. Adams,John C. Clements,Karen M. Millerach to the heart of this poetry, so deeply embedded in its language, is the frequently sober, muted quality of this style, rational, cool and formulistic, which then often, suddenly and unexpectedly, makes a transition for some moments into poetic song and form realised in experience, after which, h作者: STALL 時(shí)間: 2025-3-25 18:42 作者: 使糾纏 時(shí)間: 2025-3-25 22:56 作者: craving 時(shí)間: 2025-3-26 02:11
Nigel M. Hooperng blocks to create spatially defined geometries. The goal of biofabrication is to create engineered tissue constructs to replace damaged or diseased human tissues with full functionality. The advantage is that it can rapidly fabricate tissue constructs to meet customized needs. The biomaterials use作者: Detoxification 時(shí)間: 2025-3-26 05:21
Gillian Borland,Kyriakos M. Tanousis,Ann Agerering and advances in integration of both antimicrobial and .This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium ph作者: 得意人 時(shí)間: 2025-3-26 09:21
Marcia Moss,J. David Becherer,Marcos Milla,Gregory Pahel,Mill Lambert,Rob Andrews,Stephen Frye,Curt in integration of both antimicrobial and osteoinductive prop.This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, 作者: Feature 時(shí)間: 2025-3-26 13:03
es and increasing health care costs. Moreover, the continued increase in the number of multidrug-resistant bacteria and their fast evolution induce a serious concern with the lack of development of new antimicrobials. These problems have initiated numerous research efforts to develop more effective 作者: Germinate 時(shí)間: 2025-3-26 18:50 作者: MIME 時(shí)間: 2025-3-26 21:20
Neera Borkakoti-industrial complex and the growing incarceration rates among women of color call for the development of a black feminist liberation agenda that transforms the social and political identities of black women while offering new strategies to slow escalating incarceration rates among black mothers.作者: 閑蕩 時(shí)間: 2025-3-27 02:35 作者: GONG 時(shí)間: 2025-3-27 06:29 作者: 不真 時(shí)間: 2025-3-27 12:14
Andrew J.H. Gearing,Sally E. Adams,John C. Clements,Karen M. Millera secularised style, formed from worldly conversation, which attains its heights and its solemnity essentially through the renunciation of what is sensuous, rough and brightly coloured. Just as renunciation of material happiness is the guiding star of his poetry, so it is also of his language. A wor作者: 策略 時(shí)間: 2025-3-27 17:20
Gillian Murphy,Vera Kn?upera secularised style, formed from worldly conversation, which attains its heights and its solemnity essentially through the renunciation of what is sensuous, rough and brightly coloured. Just as renunciation of material happiness is the guiding star of his poetry, so it is also of his language. A wor作者: Outspoken 時(shí)間: 2025-3-27 19:16
Amanda J. Fosangctures. On the other hand, osteoinductive and osteoconductive materials are important to promote bone healing and regeneration. Within this framework, materials which have been employed widely are bioactive glasses (BG), calcium phosphates (CaPs) (e.g., hydroxyapatite (HA), tricalcium β-phosphate (β作者: 充氣女 時(shí)間: 2025-3-27 21:56 作者: jeopardize 時(shí)間: 2025-3-28 03:09
les can actively inhibit biofilm formation or other essential processes in the drug resistance mechanisms of bacteria. Thus, the combined use of bactericidal nanoparticles and antifouling polymers for functionalized organic–inorganic platforms has been investigated to enhance antibacterial performan作者: Root494 時(shí)間: 2025-3-28 06:57 作者: saphenous-vein 時(shí)間: 2025-3-28 12:59 作者: 集合 時(shí)間: 2025-3-28 18:16
Role of stromelysin-1 in cartilage metabolism,artilage matrix degradation observed in both rheumatoid arthritis (RA) and osteoarthritis (OA). In this review, we will describe some of the data which indicate that SLN-1 may play a role in the cartilage catabolism seen in these diseases and which suggests that this enzyme may be a reasonable targe作者: 窒息 時(shí)間: 2025-3-28 20:47
Overview of the biological roles of metalloproteinases in health and disease,ence and structural information aids not only in the elucidation of common catalytic, biosynthetic processing and regulatory mechanisms, but also is invaluable in elucidating the function of newly identified proteases. I have also provided more extensive information on the matrix metalloproteinase a作者: carbohydrate 時(shí)間: 2025-3-29 01:58
Gillian Borland,Kyriakos M. Tanousis,Ann Ageratives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices..978-3-030-34473-3978-3-030-34471-9作者: 帶來(lái)的感覺 時(shí)間: 2025-3-29 05:12 作者: FER 時(shí)間: 2025-3-29 09:59
Metalloproteinases as Targets for Anti-Inflammatory Drugs
