派博傳思國際中心

標(biāo)題: Titlebook: Mechanisms of Stimulus—Response Coupling in Platelets; J. Westwick,M. F. Scully,V. V. Kakkar Book 1985 The Editor(s) (if applicable) and T [打印本頁]

作者: antibody    時間: 2025-3-21 17:49
書目名稱Mechanisms of Stimulus—Response Coupling in Platelets影響因子(影響力)




書目名稱Mechanisms of Stimulus—Response Coupling in Platelets影響因子(影響力)學(xué)科排名




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書目名稱Mechanisms of Stimulus—Response Coupling in Platelets讀者反饋




書目名稱Mechanisms of Stimulus—Response Coupling in Platelets讀者反饋學(xué)科排名





作者: Tracheotomy    時間: 2025-3-21 22:02

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Characterisation of ADP Receptorsfibrinogen and, in the presence of sufficient calcium, to aggregate and release the contents of storage granules. These effects of ADP are competitively inhibited by the related nucleotides adenosine 5′-triphosphate (ATP) and adenosine 5′-monophosphate (AMP) which interact with the ADP receptor..
作者: 間接    時間: 2025-3-22 22:34
Fibrinogen and Platelet Functionets. These alterations are generally accomplished via a multi steps mechanism encompassing: 1) adhesion and spreading of the cells to the subendothelial matrix; 2) activation of the platelet by specific agonists; and 3) interaction of the activated platelet with cofactors which modify the adhesive p
作者: 犬儒主義者    時間: 2025-3-23 04:18
Characterisation of Factor VIII Receptorstor VIII coagulant, whose absence is the hallmark of hemophilia A, and an autosomal gene product, representing the bulk of the complex, disturbances in whose synthesis characterize the bleeding disorders collectively known as von Willebrand. s disease, from whence it derives its name, the von Willeb
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作者: 微枝末節(jié)    時間: 2025-3-24 02:14
Control and Interrelation of Aggregation and Secretion; the Roles of Ca2+, Diacylglycerol and Thromb and the various ways in which secretion and aggregation may be independent or interdependent under different experimental conditions. We shall also consider briefly shape-change and its relation to aggregation and secretion.
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作者: dry-eye    時間: 2025-3-24 10:03
Permeabilised Platelets and Exocytosisation in Ca. concentration and the nature of various factors which may modulate these responses. Permeabil-isation is achieved by exposure of a suspension of platelets to a series of intense electric fields, a treatment that seems to cause localised dielectric membrane breakdown.. The basis for the
作者: ineffectual    時間: 2025-3-24 11:25
Platelet Membranes, Eicosanoid Biosynthesis and Putative Endogenous Calcium Ionophoress and the sequence of metabolic events involved in mobilisation of arachidonic acid (AA) from membrane phospholipids; it is important to be able to separate subcellular fractions representative of surface membrane (SM) and membranes of intracellular origin (IM). In the case of the platelet, such pre
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作者: Nucleate    時間: 2025-3-24 19:02
Energy Requirements for Stimulus-Response Couplingutely dependent on the availability of ATP (1,2,3). This dependency may be due to ATP-requiring processes that 1) maintain the platelet in responsive state, 2) are involved in the stimulus-response coupling sequence and 3) drive the individual responses (Fig. 1). One way to indicate whether ATP cons
作者: phlegm    時間: 2025-3-24 23:13
Platelet Protein Phosphorylationany other cells.. It is pertinent to ask why this should be? There are probably two major reasons. First the addition of the phosphate group to a protein adds, though a fairly simple reaction, a substituent group which can substantially change the character of the protein, its conformation and its i
作者: 進(jìn)取心    時間: 2025-3-25 04:36
Receptor-Effector Coupling in Platelets: Roles of Guanine Nucleotidesreceptors. Two immediate effects of the activation of stimulatory platelet receptors have been well documented? namely inhibition of adenylate cyclase. and the cleavage of membrane phosphoinositides to diacylglycerol and inositol phosphates by phospholipase C.. Initial attempts. at correlating the i
作者: 內(nèi)行    時間: 2025-3-25 07:58
r a rigorous study of boundary integral equation methods for Helmholtz and Maxwell equations and the proofs of the theorems we refer the reader to [29]. In Section 5.4 we will then sketch an approach for ..—boundary data. These non-smooth boundary data are important for studying questions of existen
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Fibrinogen and Platelet Functiond. It is well established, however that a specific stimulus and an exogenous cofactor with adhesive properties are necessary for aggregation to occur. Early studies on patients with congenital afibrinogenemia have provided evidences that fibrinogen fulfills the role of essential cofactor in this rea
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作者: agenda    時間: 2025-3-26 04:38
Agonist-Induced Inositol Phospholipid Metabolism and Ca++ Flux in Human Platelet Activation of second messenger molecules including cAMP, cytosolic free Ca. (Caf) and 1,2-diacylglycerol (DAG).. These second messengers activate specific protein kinases, respectively cAMP-dependent protein kinase. Ca.-calmodulin-dependent protein kinase and protein kinase C. that mediate the phosphorylation
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Platelet Membranes, Eicosanoid Biosynthesis and Putative Endogenous Calcium Ionophoresor orientations. In relation to the platelet, problems arise due to the small size of this cell and its resistance to breakage by mechanical stress forces and further by the requirement to prevent aggregation and degranulation during the preparative procedures.
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作者: 西瓜    時間: 2025-3-26 22:50
Receptor-Effector Coupling in Platelets: Roles of Guanine Nucleotidesn intracellular Ca. free could activate platelets. and that phosphoinositide breakdown was closely associated with Ca. mobilization in platelets and other cells,. led to the concept that it is the receptor-mediated activation of phospholipase C that generates the signals leading to platelet aggregat
作者: 平項(xiàng)山    時間: 2025-3-27 02:43

作者: Mutter    時間: 2025-3-27 06:05
0065-2598 us response coupling in other cells, have provided interesting insights into the generality of mechanisms involved in the function of responsive cells. One may 978-1-4615-9444-4978-1-4615-9442-0Series ISSN 0065-2598 Series E-ISSN 2214-8019
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Gérard A. Marguerie,Mark. H. Ginsberg,Edward F. Plow
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D. Euan MacIntyre,W. Kenneth Pollock,Angus M. Shaw,Mark Bushfield,Linda J. MacMillan,Archibald McNic
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T. J. Hallam,A. W. M. Simpson,N. O’Connor,T. J. Rink
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F. Carey,S. Menashi,K. S. Authi,N. Hack,M. Lagarde,N. Crawford
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M. Castagna,R. Brasseur,C. Pavoine,R. Bredoux,B. Mely,J. M. Ruysschaert,S. Levy-Toledano
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作者: Incommensurate    時間: 2025-3-29 02:47
Mechanisms of Stimulus—Response Coupling in Platelets
作者: 聰明    時間: 2025-3-29 06:18
Characterisation of Human Platelet Adrenoceptorsat the adrenaline induced aggregatory response was mediated via an α-adrenoceptor on the platelet surface membrane, and in addition, the presence of β-adrenoceptors on mammalian platelets has been suggested by the anti-aggregatory effects of specific β-adrenergic agonist compounds..
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作者: exhibit    時間: 2025-3-29 12:08
0065-2598 to the understanding of platelet function are rapidly and thoroughly investigated. The intensity of this activity is attri- butable, probably, to an appreciation by research workers in the field that a satisfactory therapeutic control of platelet function has yet to be realized. Also that if and wh
作者: Flatter    時間: 2025-3-29 18:31
Structure and Organisation of Platelet Membranesl, metabolic and other functional changes when its plasma membrane is “triggered” by stimulant molecules or by contact with other cells, much research attention has been focused upon the surface membrane/plasma interface where these platelet activating events apparently occur.
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作者: 動機(jī)    時間: 2025-3-30 00:11

作者: 赤字    時間: 2025-3-30 07:35
Book 1985derstanding of platelet function are rapidly and thoroughly investigated. The intensity of this activity is attri- butable, probably, to an appreciation by research workers in the field that a satisfactory therapeutic control of platelet function has yet to be realized. Also that if and when this pr
作者: 做方舟    時間: 2025-3-30 08:37
Specific Binding of [3H]-1-O-Octadecyl Paf-Acether to Washed Human Platelets but remains unchanged in the presence of lyso-C.-Paf at 3.0–300 nM. [.H]-Paf-acether binding and its inhibition by unlabelled (R)-C.-Paf-acether is independent of buffer Ca. within the range 0–5.0mM.
作者: observatory    時間: 2025-3-30 12:30

作者: Host142    時間: 2025-3-30 18:36
Characterisation of ADP Receptorsfibrinogen and, in the presence of sufficient calcium, to aggregate and release the contents of storage granules. These effects of ADP are competitively inhibited by the related nucleotides adenosine 5′-triphosphate (ATP) and adenosine 5′-monophosphate (AMP) which interact with the ADP receptor..
作者: 柏樹    時間: 2025-3-30 20:43
Characterisation of Factor VIII Receptorstor VIII coagulant, whose absence is the hallmark of hemophilia A, and an autosomal gene product, representing the bulk of the complex, disturbances in whose synthesis characterize the bleeding disorders collectively known as von Willebrand. s disease, from whence it derives its name, the von Willebrand factor (vWf) (1).
作者: 現(xiàn)暈光    時間: 2025-3-31 02:01
Control and Interrelation of Aggregation and Secretion; the Roles of Ca2+, Diacylglycerol and Thromb and the various ways in which secretion and aggregation may be independent or interdependent under different experimental conditions. We shall also consider briefly shape-change and its relation to aggregation and secretion.




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