標題: Titlebook: Mathematical Descriptors of Molecules and Biomolecules; Applications in Chem Subhash C. Basak Book 2025 The Editor(s) (if applicable) and T [打印本頁] 作者: 桌前不可入 時間: 2025-3-21 20:01
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書目名稱Mathematical Descriptors of Molecules and Biomolecules讀者反饋學(xué)科排名
作者: endocardium 時間: 2025-3-21 21:08
Chirality Descriptors for Numerical Characterization of Enantiomers and Diastereomers,ent in chiral synthetic methods using biocatalysts, and separation technology. However, the impetus in the synthesis of enantiopure drugs may partly be attributed to regulatory policies for chiral pharmaceuticals. Enantiomers and diastereomers collectively the stereoisomers have difference in bio-ef作者: 翻布尋找 時間: 2025-3-22 00:54 作者: Mangle 時間: 2025-3-22 05:37 作者: Laconic 時間: 2025-3-22 12:26 作者: 萬花筒 時間: 2025-3-22 16:35
Descriptors from Calculated Stereo-Electronic Properties and Molecular Electrostatic Potentials (MEf molecules. They enable to visualize charge distributions and charge related properties. MEP not only allows to visualize the size and shape but also provides an invaluable tool for predicting the behavior of complex molecules. Their profiles are particularly useful for medicinal and organic chemis作者: 無畏 時間: 2025-3-22 20:51 作者: Magisterial 時間: 2025-3-22 23:44
peptide’s precursor (NACP) is the homologue of a brain-specific presynaptic protein of unknown function, identified independently in at least four other laboratories. The first report of this protein was in 1988 by Maroteaux et al.., who identified it as a component enriched in a biochemical prepara作者: 直覺沒有 時間: 2025-3-23 04:45 作者: 尖牙 時間: 2025-3-23 05:50 作者: Invertebrate 時間: 2025-3-23 11:01
Ramanathan Natarajan,Subhash C. Basak,Claudiu N. Lungus and oxidative stress, protein misfolding and translational dysfunction, autophagy and microglia activation. This indicates that although the original cause may differ in individual diseases or even subtypes of certain disorders, these disrupted common cell functions and signaling, together with ag作者: Alopecia-Areata 時間: 2025-3-23 17:55
Suman K. Chakravartin, resulting in a broad range of neurological and non-neurological comorbidities. The concept of epileptic encephalopathies entails that the encephalopathy aspect of the overall condition is primarily driven by the epileptic activity of the disease, which often manifests as specific and pathological作者: grenade 時間: 2025-3-23 21:05
Arpita Poddar,Ranita Pal,Shanti Gopal Patra,Pratim Kumar Chattarajn deficiency, impaired effectiveness of insulin action, or both. The prevalence of Type 2 diabetes mellitus (T2DM) increases with age and dementia also increases its incidence in later life. Recent studies have revealed that T2DM is a risk factor for cognitive dysfunction or dementia, especially tho作者: doxazosin 時間: 2025-3-24 01:39
Denis Sabirov,Alexandra Zimina,Igor Shepelevich-onset alzheimer’s disease (LOAD) is the result of multiple susceptibility genes, each one contributing a small amount to the total risk. Smaller-scale genetic association studies identified the e4 allele of the apolipoprotein E (APOE) gene as the best established LOAD risk factor, increasing risk b作者: crumble 時間: 2025-3-24 05:45
Apurba K. Bhattacharjee-onset alzheimer’s disease (LOAD) is the result of multiple susceptibility genes, each one contributing a small amount to the total risk. Smaller-scale genetic association studies identified the e4 allele of the apolipoprotein E (APOE) gene as the best established LOAD risk factor, increasing risk b作者: Esalate 時間: 2025-3-24 07:57 作者: arboretum 時間: 2025-3-24 11:30 作者: 來自于 時間: 2025-3-24 18:28 作者: PANG 時間: 2025-3-24 19:16
Hierarchy of Descriptors: From Topology to Bio-descriptors,are used to quantify salient aspects of molecular and biomolecular strucuraes. This chapter discusses the nature and methods of calculations of various classes of chemodescripotors and biodescriptors developed and used by reseaerchers during the past century.作者: AMBI 時間: 2025-3-25 00:37 作者: Noctambulant 時間: 2025-3-25 06:25 作者: Distribution 時間: 2025-3-25 10:47 作者: 仇恨 時間: 2025-3-25 12:37 作者: 高深莫測 時間: 2025-3-25 16:27
Mathematical Descriptors of Molecules and BiomoleculesApplications in Chem作者: definition 時間: 2025-3-25 20:35
Chirality Descriptors for Numerical Characterization of Enantiomers and Diastereomers,somers. that is the conventional molecular descriptors are incapable of differentiating stereoisomers. In order to overcome this limitation several attempts have been taken in developing descriptors that differentiate stereoisomers namely enantiomers and diastereomers. Chirality about carbon atom(s)作者: 帶來 時間: 2025-3-26 02:59
Descriptors from Calculated Stereo-Electronic Properties and Molecular Electrostatic Potentials (ME studies ranging from mutagenicity, carcinogenicity, to cardiotonics, anti-inflammatory, malarial, leishmanial, insect repellency, organo-phosphorous poisoning and antiviral compounds including identification of potential anti Covid-19 compounds from author’s laboratory.作者: Resign 時間: 2025-3-26 04:18 作者: 委屈 時間: 2025-3-26 11:07
1938-1743 synthesis, new drug discovery, hazard assessment of chemicals, and computational biology of emerging global pathogens. The book also discusses the applications of alignment-free sequence descriptors (AFSDs) in978-3-031-67843-1978-3-031-67841-7Series ISSN 1938-1743 Series E-ISSN 1938-1751 作者: Accord 時間: 2025-3-26 16:23
phosphorylated on serine residues, and have suggested it is also phosphorylated on tyrosine.; they named the protein Phosphoneuroprotein-14-kDa (PNP-14). More recently, Jakes et al.., using an antibody originally raised against paired helical filaments, detected two forms of the same human protein, 作者: 爵士樂 時間: 2025-3-26 17:46
Subhash C. Basak, the relative “dose” of TBI, such as the frequency and severity of injury, associated with risk of CTE?remains unknown. As such, there is a clear and pressing need to improve the recognition and diagnosis of CTE and to identify mechanistic links between TBI and chronic neurodegeneration.作者: Defense 時間: 2025-3-26 21:55
Marjan Vra?ko,Subhash C. Basakgic challenge studies, postmortem analyses and a recent sufficiently powered genome-wide association study and copy number variant studies provide compelling evidence that NMDA receptor hypofunction is an important pathophsysiologic feature of schizophrenia. Silencing the gene encoding serine racema作者: GLEAN 時間: 2025-3-27 03:09
Ramanathan Natarajan,Subhash C. Basak,Claudiu N. Lungu accumulation, nuclear translocation of the mitochondria protein AIF, and large-scale DNA cleavage. Understanding the mechanisms and interactions of cell death signaling will not only help to develop neuroprotective strategies to halt neurodegeneration, but also provide biomarkers for monitoring dis作者: 颶風(fēng) 時間: 2025-3-27 08:24 作者: Commonwealth 時間: 2025-3-27 12:43 作者: 牢騷 時間: 2025-3-27 16:20
Denis Sabirov,Alexandra Zimina,Igor Shepelevichgions, in large international consortia with sufficient number of cases and controls. The four largest LOAD GWAS consortia joined forces forming a mega-consortium known as the International Genomics of Alzheimer’s Project (IGAP) and conducted a mega-meta-analysis of 25,500 LOAD cases and 48,500 unaf作者: 土坯 時間: 2025-3-27 18:34 作者: Paleontology 時間: 2025-3-27 23:55
Ziyun Zhou,Lorenza Pacini,Laurent Vuillon,Claire Lesieur,Guang Huwill offer the biomedical sciences new insight for the study of neurodegenerative diseases, multifactorial complex, and rare diseases. In this chapter, an overview of the current genetic and epigenetic progresses in AD, FTD, PD, and ALS, reached by the application of the new genetic technologies, wi作者: 搜尋 時間: 2025-3-28 03:05
Book 2025 biodescriptors. Currently there is a steady increase in the use of data analytics and model-based decision support systems in basic and applied research in chemoinformatics, bioinformatics, pharmaceutical drug design, predictive toxicology, and computational biology.? Since there are a plethora of 作者: 性冷淡 時間: 2025-3-28 06:53 作者: 確定的事 時間: 2025-3-28 13:01 作者: 彎彎曲曲 時間: 2025-3-28 14:56
1938-1743 phasis on computer-assisted organic synthesis.Provides a com.This book provides an up-to-date overview of data driven and evidence-based empirical approaches in the efficient application of chemodescriptors and biodescriptors. Currently there is a steady increase in the use of data analytics and mod作者: 直言不諱 時間: 2025-3-28 20:42
Quantitative Structure-Activity Analysis Using Conceptual DFT and Information Theory-based Descriptarameters are considered as the dependent variable, whereas some CDFT descriptors are used as the independent variables. On the other hand, IT descriptors are also used to develop the QSAR model for describing different structural parameters and properties of the chemical systems.作者: 彈藥 時間: 2025-3-29 01:09 作者: 剛開始 時間: 2025-3-29 05:32
Robert W. Schmiederedin microbiology along with nanotechnology applications for efficient solutions to cancer detection, biosensors, vaccines research, ?agriculture, wastewater management etc..978-3-031-49935-7978-3-031-49933-3作者: 考博 時間: 2025-3-29 08:24 作者: 邊緣帶來墨水 時間: 2025-3-29 14:03 作者: glacial 時間: 2025-3-29 18:26
Book 1990dologische und methodische Grundsatzfragen des empirischen Zugangs zur Verbrechenswirklichkeit, der erfahrungswissenschaftlichen Erfassung des T?ters in seinen sozialen Bezügen, der forensischen Begutachtung und der (therapeutischen) Behandlung.