標題: Titlebook: Mass Spectrometry in Biology & Medicine; A. L. Burlingame,Steven A. Carr,Michael A. Baldwin Book 2000 Springer Science+Business Media New [打印本頁] 作者: sesamoiditis 時間: 2025-3-21 18:55
書目名稱Mass Spectrometry in Biology & Medicine影響因子(影響力)
書目名稱Mass Spectrometry in Biology & Medicine影響因子(影響力)學(xué)科排名
書目名稱Mass Spectrometry in Biology & Medicine網(wǎng)絡(luò)公開度
書目名稱Mass Spectrometry in Biology & Medicine網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Mass Spectrometry in Biology & Medicine被引頻次
書目名稱Mass Spectrometry in Biology & Medicine被引頻次學(xué)科排名
書目名稱Mass Spectrometry in Biology & Medicine年度引用
書目名稱Mass Spectrometry in Biology & Medicine年度引用學(xué)科排名
書目名稱Mass Spectrometry in Biology & Medicine讀者反饋
書目名稱Mass Spectrometry in Biology & Medicine讀者反饋學(xué)科排名
作者: creatine-kinase 時間: 2025-3-21 22:13 作者: 叢林 時間: 2025-3-22 00:57 作者: 感情脆弱 時間: 2025-3-22 07:58 作者: 不透明性 時間: 2025-3-22 11:32
Ewan J. Nettleton,Carol V. Robinsontrategie. Die Strategie gibt Orientierung in der gesamten Organisation und fokussiert. Sie ist kein statischer Plan, sondern ein dynamischer Prozess. Das hei?t auch, dass das Thema des st?ndigen Anpassens, überarbeitens und Verbesserns stetig eines der wichtigsten Aktions- und Reflexionsfeldes für G作者: tinnitus 時間: 2025-3-22 13:54 作者: 綠州 時間: 2025-3-22 18:14
Jeffrey G. Mandell,Arnold M. Falick,Elizabeth A. Komivestrategie. Die Strategie gibt Orientierung in der gesamten Organisation und fokussiert. Sie ist kein statischer Plan, sondern ein dynamischer Prozess. Das hei?t auch, dass das Thema des st?ndigen Anpassens, überarbeitens und Verbesserns stetig eines der wichtigsten Aktions- und Reflexionsfeldes für G作者: Comedienne 時間: 2025-3-23 00:25 作者: Congestion 時間: 2025-3-23 04:42
Paul Tempst,Hediye Erdjument-Bromage,Matthew C. Posewitz,Scott Geromanos,Gordon Freckleton,Anita Gretrategie. Die Strategie gibt Orientierung in der gesamten Organisation und fokussiert. Sie ist kein statischer Plan, sondern ein dynamischer Prozess. Das hei?t auch, dass das Thema des st?ndigen Anpassens, überarbeitens und Verbesserns stetig eines der wichtigsten Aktions- und Reflexionsfeldes für G作者: 商業(yè)上 時間: 2025-3-23 07:49 作者: Scintillations 時間: 2025-3-23 10:22 作者: 捐助 時間: 2025-3-23 14:59 作者: 做作 時間: 2025-3-23 20:47 作者: 包裹 時間: 2025-3-24 02:05
Eva-Christina Müller,Brigitte Wittmann-Liebold,Albrecht OttoInnovationsmanagement.Branchenfokus: Banken, ImmobilienNachhaltiges Wirtschaften ist eine Zukunftsaufgabe, der sich das Buch aus verschiedenen Perspektiven widmet. Im Mittelpunkt steht dabei die Frage, wie die Wettbewerbsf?higkeit unseres Landes erhalten, gest?rkt und damit die Zukunftsperspektiven 作者: FLAIL 時間: 2025-3-24 05:54 作者: Water-Brash 時間: 2025-3-24 10:06
Xiaolong Zhang,Christopher J. Herring,Jun Qin deutlich geworden sein. Wir vermuteten deshalb, dass ihr Erfolg nicht von Merkmalen der angesprochenen Haushalte allein abh?ngt, sondern auch von den Bedingungen in deren Nachbarschaft. Es ging uns um die Frage, ob eine eher herk?mmliche Interventionsmethode in hoch koh?siven Nachbarschaften erfolg作者: 錯事 時間: 2025-3-24 13:54 作者: ensemble 時間: 2025-3-24 15:27
Gerald W. Hart,Robert N. Cole,Lisa K. Kreppel,C. Shane Arnold,Frank I. Comer,Sai Iyer,Xiaogang Chengalstruktur von Wohngebieten in Verbindung mit der r?umlichen Struktur und der vorhandenen Organisation mit ihren Institutionen die Bildung koh?siver Nachbarschaften sowohl unterstützen als auch hemmen kann. Auf der Seite der Sozialstruktur wurde postuliert, dass es vor allem die Homogenit?t der Bewo作者: 圓桶 時間: 2025-3-24 21:58
A New Delayed Extraction MALDI-TOF MS-MS for Characterization of Protein Digests,n of selected spots by one or more endopeptidases followed by generation of peptide mass maps using MALDI-TOF MS is now widely accepted as the first step toward identifying and characterizing the proteins [2]. Following the development of delayed extraction techniques for MALDI [3–5], and improved s作者: hangdog 時間: 2025-3-25 02:03
Measurements of Protein Structure and Noncovalent Interactions by Time-of-Flight Mass Spectrometry lent modifications can occur in the corresponding protein sequence before the protein is fully functional, so it is important to know the actual protein sequence to understand its function [1, 2]. It is equally important to determine the higher order protein structure, and its interaction with other作者: 無價值 時間: 2025-3-25 06:58
Isotopic Amplification, H/D Exchange, and Other Mass Spectrometric Strategies for Characterization mapped by mass spectrometry. First, isotopic amplification of proteins, achieved by expression from growth media doubly-depleted in carbon-13 and nitrogen-15, narrows, amplifies, and shifts the isotopic mass distribution, to identify definitively the ?monoisotopic“ species (i. e., the only species w作者: 瑣碎 時間: 2025-3-25 10:10 作者: 保留 時間: 2025-3-25 11:44
Studying Noncovalent Small Molecule Interactions with Protein and RNA Targets by Mass Spectrometry,tical research. To develop new therapies at an increasing pace, more new drugs need to be synthesized or discovered, more novel macromolecular targets need to be identified, and compounds need to be characterized, screened and evaluated at a faster rate. Advances and application of combinatorial che作者: troponins 時間: 2025-3-25 17:57
Identification of Protein-Protein Interfaces by Amide Proton Exchange Coupled to MALDI-TOF Mass Spees. The method has broad application to the study of protein conformation and folding and to the study of protein-ligand interactions and requires no modifications of the instrument. Amide protons were allowed to exchange with deuterons in buffered D.O, pD 7.25 at room temperature. Exchanged deutero作者: 惰性氣體 時間: 2025-3-25 21:55
Electron Capture Dissociation Produces Many More Protein Backbone Cleavages Than Collisional and , avage products [R-C(OH)=NH + (n-m)H]. (.) + [·R’ + mH] . (.·), whereas conventional activation methods mainly cleave the amide bond R-C—/—NH-R’ to yield . and . ions. In the postulated cleavage mechanism, electron capture to form (M + nH).reduced molecular ions is followed by the transfer of the lab作者: 枯燥 時間: 2025-3-26 00:39
Protein Micro-Characterization by Mass Spectrometry: Sample Handling and Data Flow,s patterns of proteolytic fragments, or dissociation products thereof, to query databases [1–6]. Two issues, however, need to be addressed at the present time. Are we ready for high throughput analyses in a reliable, efficient and timely manner, and to apply these tools towards rationally selected, 作者: 入會 時間: 2025-3-26 08:07
Towards an Integrated Analytical Technology for the Generation of Multidimensional Protein Expressit expressed by a tissue or differentiated cell [1]. In the most commonly used approach to proteome analysis the proteins extracted from the cell or tissue to be analyzed are separated by high resolution two dimensional gel electrophoresis (2DE), detected in the gel by staining or, if radiolabeled, b作者: 仔細閱讀 時間: 2025-3-26 11:28
Sequencing the Primordial Soup,ar protein differences between whole cells (diseased vs. healthy) or between other complex biological fluids are important to understanding protein function. Once the structure and interactions of all proteins are characterized — in physiological and pathological situations — therapeutic strategies 作者: 階層 時間: 2025-3-26 16:05
Coaxial Nanospray Coupled with a Hybrid Quadrupole/Time-of-Flight Tandem Mass Spectrometer for Prot pharmaceutical companies discover and develop drugs. These projects have two principal goals — the identification of the best disease genes/targets on which to initiate drug discovery programs, and the identification of patients who will respond favorably to drugs based on their genotype. To accomp作者: Coordinate 時間: 2025-3-26 17:51 作者: Immunoglobulin 時間: 2025-3-26 22:15 作者: braggadocio 時間: 2025-3-27 03:52
Deciphering Functionally Important Multiprotein Complexes by Mass Spectrometry,n the enzymatic activity can be reproduced in an . experiment and the chemical mechanisms of the reaction can be elucidated in detail [1]. However if the enzyme is involved in regulation of a cellular activity it seldom acts by itself. Enzymatic activity is controlled and targeted to specific substr作者: FACT 時間: 2025-3-27 06:07
Investigation of Apoptosis-Involved Processes by Mass Spectrometric Identification of the Apoptosishe programmed cell death plays a major role in development, homeostasis and immune response in multicellular organisms and controls lymphocyte growth and selection, this research area has not attracted great interest in the past for several reasons. First, the efficient disposal of apoptotic cells b作者: 形容詞 時間: 2025-3-27 09:47
,IR-MALDI — Softer Ionization in MALDI-MS for Studies of Labile Macromolecules,ectrospray ionization (ESI) and MALDI are the two major soft ionization techniques for the intact analysis of macromolecules by mass spectrometry. While MALDI-MS provides inherently fast data acquisition and spectra facile for data analysis, ESI is considered to be the softer of the two techniques a作者: 格子架 時間: 2025-3-27 16:49
Identification of , Phosphorylation Sites with Mass Spectrometry,n modulate enzyme activity, alter affinity to other proteins, and transmit signals through kinase cascades that often are branched and interactive. To understand the molecular basis of these regulatory mechanisms, it is necessary to determine the sites that are phosphorylated .. Mass spectrometry is作者: 辭職 時間: 2025-3-27 18:59 作者: 教育學(xué) 時間: 2025-3-27 23:12
,Glycosylation of Proteins — A Major Challenge in Mass Spectrometry and Proteomics,t most proteins within the nucleus and cytoplasm are also dynamically modified by the addition and removal of saccharides [1]. Indeed, in eukaryotes most polypeptides are glycosylated. Extracellular protein-bound glycans are generally complex and large, whereas cytosolic and nuclear glycans are ofte作者: 殺人 時間: 2025-3-28 03:14 作者: 安心地散步 時間: 2025-3-28 07:59 作者: Brain-Waves 時間: 2025-3-28 11:00 作者: 清唱劇 時間: 2025-3-28 16:30
Electron Capture Dissociation Produces Many More Protein Backbone Cleavages Than Collisional and , n from a single ECD spectrum of multiply protonated ubiquitin (76 amino acids) provides, ., ~90% of its sequence, and ECD of smaller proteins and peptides generally provides 90%–100% of the sequence. However, this coverage decreases for proteins >10 kDa, and proteins >20 kDa only undergo multiple re作者: Immunization 時間: 2025-3-28 20:57 作者: scotoma 時間: 2025-3-29 02:31 作者: 阻撓 時間: 2025-3-29 03:32 作者: Bumble 時間: 2025-3-29 09:11 作者: 啟發(fā) 時間: 2025-3-29 14:45
Deciphering Functionally Important Multiprotein Complexes by Mass Spectrometry,vides clues to understanding in molecular detail how cellular activities are carried out. Dissection of the protein complex places its individual subunits in a context of the specific cellular function carried out by the entire assembly. Taken together with specific motifs recognized in the sequence作者: 痛苦一生 時間: 2025-3-29 18:00
Investigation of Apoptosis-Involved Processes by Mass Spectrometric Identification of the Apoptosiss of membrane integrity. In contrast, apoptotic cell death is characterized by controlled autodigestion of functional, important proteins of the cell connected with cellular shrinkage, membrane blebbing and chromatin condensation. The nuclear DNA of apoptotic cells is often fragmented. The membrane 作者: Overstate 時間: 2025-3-29 21:12 作者: 認為 時間: 2025-3-30 01:59 作者: Classify 時間: 2025-3-30 04:43 作者: 顯赫的人 時間: 2025-3-30 11:55 作者: Cloudburst 時間: 2025-3-30 14:47 作者: 圓錐體 時間: 2025-3-30 17:37 作者: Cougar 時間: 2025-3-31 00:03 作者: Encoding 時間: 2025-3-31 02:19 作者: ineffectual 時間: 2025-3-31 08:14
Jeffrey G. Mandell,Arnold M. Falick,Elizabeth A. KomivesAuf Basis neuer Konstellationen k?nnen sich Anpassungen an der Strategie ergeben. Mindestens einmal alle zw?lf Monate sollte die Strategieüberprüfung als fester Meilenstein im Gesch?ftsjahr eingeführt werden. Dieses Kapitel gibt Ihnen die hierfür passenden Fragen an die Hand.作者: 有權(quán) 時間: 2025-3-31 11:28
Roman A. Zubarev,Einar K. Fridriksson,David M. Horn,Neil L. Kelleher,Nathan A. Kruger,Mark A. Lewis,Auf Basis neuer Konstellationen k?nnen sich Anpassungen an der Strategie ergeben. Mindestens einmal alle zw?lf Monate sollte die Strategieüberprüfung als fester Meilenstein im Gesch?ftsjahr eingeführt werden. Dieses Kapitel gibt Ihnen die hierfür passenden Fragen an die Hand.
