標(biāo)題: Titlebook: Levodopa-Induced Dyskinesia in Parkinson‘s Disease; Susan H. Fox,Jonathan M. Brotchie Book 2014 Springer-Verlag London 2014 Parkinson‘s di [打印本頁] 作者: 兇惡的老婦 時(shí)間: 2025-3-21 17:45
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease影響因子(影響力)
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease影響因子(影響力)學(xué)科排名
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書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease被引頻次
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease被引頻次學(xué)科排名
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書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease年度引用學(xué)科排名
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease讀者反饋
書目名稱Levodopa-Induced Dyskinesia in Parkinson‘s Disease讀者反饋學(xué)科排名
作者: 擁護(hù) 時(shí)間: 2025-3-21 21:55 作者: galley 時(shí)間: 2025-3-22 02:44 作者: 遭受 時(shí)間: 2025-3-22 07:25
Wai Kin D. Ko,Matthieu Bastide,Erwan Bezardus dem Interessenbegriff selbst, oder aus seiner anthropologischen Dimension, als vielmehr aus der Entscheidung für eine bestimmte Demokratievorstellung. Dies wird deutlich, wenn er darauf hinweist, da? ?das Bekenntnis zur ?westlichen Demokratie‘... die Anerkennung der Befugnisse der Bürger (erforde作者: 事物的方面 時(shí)間: 2025-3-22 09:40 作者: 口訣 時(shí)間: 2025-3-22 13:56 作者: 脫毛 時(shí)間: 2025-3-22 18:27
Vincent A. Jourdain PhD,Nicolas Morin B.Pharm, MSc,Thérèse Di Paolo PhDnbegriff in den verschiedenen Traditionen der Sozialtheorie vom Funktionalismus bis zum Neomarxismusverwendet wird. Daran anschlie?end wird der Versuch unternommen, Interessen in ihrem multidimensionalen und prozesshaften Charakter als ?Interessierung“ neu zu fassen und in ihren Implikationen für Th作者: Neuropeptides 時(shí)間: 2025-3-22 23:11
Tom H. Johnston PhD,Paula Ravenscroft PhD,Michael P. Hill PhDkt zwischen Institutionen lassen stets neue soziale Konstella- tionen entstehen, die die historische Entwicklung offen halten. Aus Interes- sen, Ideen und Institutionen entstehen soziale Ordnungen, die die Lebensver- haltnisse, die Personalitat und die Wertorientierung der Menschen bestim- men. Max 作者: 睨視 時(shí)間: 2025-3-23 03:38 作者: LASH 時(shí)間: 2025-3-23 08:37
,Dyskinesia Rating Scales in Parkinson’s Disease, RDRS can be chosen for disability. The UDysRS has a very strong clinimetric profile and combines both patient perceptions and objective assessments of disability and impairment, providing the most comprehensive measurement tool for the overall burden of dyskinesia.作者: 柏樹 時(shí)間: 2025-3-23 18:45
Pharmacological Treatment Options for Levodopa-Induced Dyskinesia,lude the antiglutamatergic drug amantadine and the antipsychotic clozapine (which carries a risk of leukopenia and requires regular blood checks)..In patients with motor complications refractory to all adjustments of oral and transdermal treatments and where deep brain stimulation is either contrain作者: Macronutrients 時(shí)間: 2025-3-23 23:48 作者: alliance 時(shí)間: 2025-3-24 02:23
Pharmacological Properties of Levodopa, which is thought to be a key determinant underlying the dyskinetic state. Therapeutic approaches that would produce continuous drug delivery (CDD) and ensuing continuous dopaminergic stimulation (CDS) have been actively sought. After a brief historical review, this chapter summarizes the biochemica作者: 排出 時(shí)間: 2025-3-24 07:27 作者: 保守黨 時(shí)間: 2025-3-24 11:03 作者: 男學(xué)院 時(shí)間: 2025-3-24 16:24
Involvement of the Cholinergic System in Levodopa-Induced Dyskinesia, acting at nAChRs, with the α4β2, α6β2, and α7 receptor subtypes all contributing to the occurrence of LID. An involvement of multiple subtypes in LID is also supported by studies with drugs targeting select nAChR populations. Notably, nicotine and nAChR drugs did not worsen parkinsonism in any anim作者: blackout 時(shí)間: 2025-3-24 19:32
New Clinical Trials for Levodopa-Induced Dyskinesia,odopa-sparing agents on LID is also being investigated, both in early and advanced PD. Moreover, non-dopaminergic agents are being studied as add-on therapies in established LID. Such agents are also being studied in early PD, either as monotherapy to improve parkinsonian symptoms without causing dy作者: 流行 時(shí)間: 2025-3-25 02:43
ced Dyskinesia in Parkinson’s Disease. is aimed at an international audience of movement disorder neurologists; neuroscientists; trainees and graduate and post-graduate students..978-1-4471-7238-3978-1-4471-6503-3作者: 混合物 時(shí)間: 2025-3-25 06:23
Elisabetta Tronci,Camino Fidalgo,Manolo Cartan anschlie?end wird der Versuch unternommen, Interessen in ihrem multidimensionalen und prozesshaften Charakter als ?Interessierung“ neu zu fassen und in ihren Implikationen für Th978-3-658-33726-1978-3-658-33727-8作者: MITE 時(shí)間: 2025-3-25 11:08 作者: contradict 時(shí)間: 2025-3-25 13:53
Levodopa-Induced Dyskinesia in Parkinson‘s Disease作者: 閑聊 時(shí)間: 2025-3-25 18:16
Levodopa-Induced Dyskinesia in Parkinson‘s Disease978-1-4471-6503-3作者: 遵循的規(guī)范 時(shí)間: 2025-3-25 22:53 作者: 喧鬧 時(shí)間: 2025-3-26 02:22 作者: 意見一致 時(shí)間: 2025-3-26 04:24 作者: Harbor 時(shí)間: 2025-3-26 12:32
978-1-4471-7238-3Springer-Verlag London 2014作者: 規(guī)章 時(shí)間: 2025-3-26 13:55
https://doi.org/10.1007/978-1-4471-6503-3Parkinson‘s disease; clinical trial; dyskinesia; levodopa; levodopa-induced dyskinesia; parkinsonism; prec作者: cyanosis 時(shí)間: 2025-3-26 20:16 作者: grovel 時(shí)間: 2025-3-26 22:22 作者: 浮雕寶石 時(shí)間: 2025-3-27 01:43 作者: Negotiate 時(shí)間: 2025-3-27 09:11 作者: 火光在搖曳 時(shí)間: 2025-3-27 10:28 作者: Fortify 時(shí)間: 2025-3-27 14:52 作者: 尖酸一點(diǎn) 時(shí)間: 2025-3-27 20:11 作者: exclusice 時(shí)間: 2025-3-27 23:06
,Features and Mechanisms of Diphasic Dyskinesia in Parkinson’s Disease,the beginning and at the end, but not at the peak, of the levodopa effect in long-term treated Parkinson’s disease patients. The most commonly affected subjects with this form of dyskinesia are those who have an early onset of the disease, approaching 20 % of globally treated parkinsonian patients. 作者: 惰性女人 時(shí)間: 2025-3-28 04:17 作者: 延期 時(shí)間: 2025-3-28 08:12
Dopamine Receptors and Levodopa-Induced Dyskinesia,physiology of L-3,4-dihydroxyphenylalanine (.-DOPA)-induced dyskinesias (LID) in parkinsonian patients and animal models. Altered dopaminergic neurotransmission in the basal ganglia are observed in LID. Two conditions are necessary for their appearance: (1) loss of DA in nigrostriatal pathway and (2作者: Ptosis 時(shí)間: 2025-3-28 14:12 作者: Infantry 時(shí)間: 2025-3-28 16:00
The Opioid System in Levodopa-Induced Dyskinesia,the development and expression of levodopa-induced dyskinesia (LID), following long-term dopamine replacement therapy in Parkinson’s disease (PD), are myriad changes in both opioid receptor levels as well as the stoichiometry and processing of endogenous opioid peptides. Notably, in both patients an作者: Abrupt 時(shí)間: 2025-3-28 20:53 作者: 忘恩負(fù)義的人 時(shí)間: 2025-3-28 23:31 作者: capsaicin 時(shí)間: 2025-3-29 03:28 作者: 抱怨 時(shí)間: 2025-3-29 09:01 作者: 天賦 時(shí)間: 2025-3-29 15:09
New Clinical Trials for Levodopa-Induced Dyskinesia,t completely understood, preclinical studies have provided more insights into the underlying mechanisms. To date, however, translation to human therapeutic trials has generally been disappointing. Two main therapeutic strategies are recognized: (1) agents that may . the development of dyskinesia and作者: 參考書目 時(shí)間: 2025-3-29 15:58
Preclinical Models of Levodopa-Induced Dyskinesia,ority of PD patients. Animal models are the most important preclinical tool for molecular investigations of LID mechanisms and therapeutic targets..Over the last two decades, models of LID have been developed in both nonhuman primate and rodent species, recapitulating several aspects of the human dy作者: Morsel 時(shí)間: 2025-3-29 21:39
n, um Ph?nomene des Internetzeitalters wie ?Filter-Bubbles“ zu erkl?ren. Besonders die starke Verbreitung der Ideen einer flachen Erde und damit zusammenh?ngender Behauptungen, die auf YouTube geteilt wurden, sowie die in den Jahren 2017–2019 stattgefundenen ?Flat Earth International Conferences“ ha作者: Abominate 時(shí)間: 2025-3-30 00:34
Panagiotis Zis MSc, MRCPsych, PhD,Kallol Ray Chaudhuri DSc, MD, FRCP,Michael Samuel MD, FRCPtlichen Wahrnehmung neben vielen positiven Assoziationen leider aber auch Schlagworte wie Studienabbruchquote oder Fachkr?ftemangel verbunden. Daher ist es nachvollziehbar, dass zahlreiche Initiativen dafür einstehen, die Bildung im MINT-Bereich zu st?rken, um negativen Entwicklungen entgegenzuwirke作者: Picks-Disease 時(shí)間: 2025-3-30 04:54
Renato P. Munhoz MD, MSc,Michael S. Okun MDs Menschen — weitgehend aus der Beobachtung des empirischen Menschen, des Menschen wie er ist, deduziert. Die kategoriale Bedeutung des Interesses wurde aus dem Tatbestand abgeleitet; da? der Mensch in seinem politisch-sozialen Verhalten sich weitgehend von dem Bestreben motivieren l??t, seinen Inte作者: 昏迷狀態(tài) 時(shí)間: 2025-3-30 10:37 作者: 擔(dān)心 時(shí)間: 2025-3-30 15:33 作者: 甜得發(fā)膩 時(shí)間: 2025-3-30 17:41
Philippe Huotlysieren. Es scheint ein ?empirischer Spatz“ unter der Last eines ?theoretischen Elefanten“ erdrückt zu werden. Anhand rein illustrativer Kleinstudien über so unterschiedliche Konflikte und Problemfelder der internationalen Politik wie der Kuba-Krise oder der Handelsbeziehungen zwischen den gro?en I作者: 基因組 時(shí)間: 2025-3-30 22:05 作者: Saline 時(shí)間: 2025-3-31 01:27
Elisabetta Tronci,Camino Fidalgo,Manolo Cartat verschiedener Theorieans?tzeDieses Buch handelt von Interessen und ihrer Rolle im sozialen Handeln. Was sind Interessen, wie entstehen sie, und wie werden sie im sozialen Handeln praktisch wirksam? Und in welchen Beziehungen stehen Interessen zu anderen Handlungsorientierungen wie Werten oder Emot作者: 寬度 時(shí)間: 2025-3-31 05:30
Tom H. Johnston PhD,Paula Ravenscroft PhD,Michael P. Hill PhDammenhang. Die Vermittlung von Interessen und Ideen durch Institutio- nen ist das gemeinsame Thema. Auch wenn nicht immer auf Max Weber ausdriicklich Bezug genommen wird, so folgen diese Aufsatze doch der von ihm entwickelten Problemsteliung. Interessen sind ideenbezogen, sie bediir- fen eines Wertb作者: 優(yōu)雅 時(shí)間: 2025-3-31 11:24 作者: 抱怨 時(shí)間: 2025-3-31 15:40
al trial design.This book aims to provide a single reference source on levodopa-induced dyskinesias (LID) from ‘bench to bedside’..Initial chapters review the clinical features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to 作者: ARENA 時(shí)間: 2025-3-31 20:05
Book 2014al features and phenomenology of LID with video examples; epidemiology and genetic risk factors for LID are covered as a background to understanding risk factors for developing LID. The following chapters cover the latest preclinical studies aiming to understand the pathophysiology of LID at the cel作者: 小淡水魚 時(shí)間: 2025-4-1 01:01 作者: 恫嚇 時(shí)間: 2025-4-1 02:00 作者: chemoprevention 時(shí)間: 2025-4-1 08:53 作者: debacle 時(shí)間: 2025-4-1 13:18 作者: ACRID 時(shí)間: 2025-4-1 18:15 作者: 方舟 時(shí)間: 2025-4-1 21:33 作者: Override 時(shí)間: 2025-4-1 23:26 作者: 極小 時(shí)間: 2025-4-2 06:18
The Serotonergic System in Levodopa-Induced Dyskinesia,ate models of PD, suggesting a possible clinical application. This chapter will provide an overview of these preclinical findings concerning the role of serotonergic neurons and serotonergic receptors in the appearance of LID, with a brief review of relevant clinical studies.作者: Interlocking 時(shí)間: 2025-4-2 07:25
Cannabinoids and Levodopa-Induced Dyskinesia,ews recent investigations on the relationships between endocannabinoids and other neurotransmitter/neuromodulator systems in the basal ganglia, with the intent to underline their relevance for the pathophysiology of levodopa-induced dyskinesia and discuss new pharmacological approaches for their treatment.
