作者: SEMI 時(shí)間: 2025-3-21 21:18
The Science and Technology Challenge: How to Find New Drugs,company would ever be able to enter the pharmaceutical industry and to compete with the industry’s giants (see Robbins-Roth 2001). However, some entrepreneurs were not impressed with this challenge and created an entirely new industry — the biotechnology industry. Besides an innovative management ap作者: 大量殺死 時(shí)間: 2025-3-22 01:57
The Pipeline Management Challenge: How to Shape the Innovation-Flow,cancer, 120 for heart diseases and strokes, 26 for Alzheimer’s disease, 25 for diabetes, and more than 200 for special needs of children. In order to maintain or exceed double-digit growth expectations, pharmaceutical companies are required to deliver between two and four new drugs every year. Given作者: 精確 時(shí)間: 2025-3-22 05:57 作者: Ondines-curse 時(shí)間: 2025-3-22 12:29
Appendices,end of the industry average; this has enabled Novartis to invest significantly in organic growth. In addition, Novartis consolidated activities with the divestment of non-core businesses. As a first and significant step, the company spun-off its CHF 8 billion specialty chemicals business Ciba SC in 作者: 恃強(qiáng)凌弱 時(shí)間: 2025-3-22 15:08 作者: Cabg318 時(shí)間: 2025-3-22 19:49
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitzreets, tripping and falling, and people laughing. Such a reaction is one of the enduring puzzles of humour philosophy—that is, why would a scenario otherwise so pathetic activate sensations of the comic, and how should humour be classified in this and other regards. Other scenarios that are actually作者: inclusive 時(shí)間: 2025-3-22 22:27 作者: altruism 時(shí)間: 2025-3-23 03:51 作者: 使出神 時(shí)間: 2025-3-23 07:18
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitz existence-spheres is not as strange as it might at first appear. To do this, I shall draw upon M. Jamie Ferreira’s work on the role of the imagination in ethical and religious transitions.. Taking up a strand of the argument of Chapter 2, I shall consider the idea that the chief instrument of exist作者: 夸張 時(shí)間: 2025-3-23 12:37
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitz existence-spheres is not as strange as it might at first appear. To do this, I shall draw upon M. Jamie Ferreira’s work on the role of the imagination in ethical and religious transitions.. Taking up a strand of the argument of Chapter 2, I shall consider the idea that the chief instrument of exist作者: MUTED 時(shí)間: 2025-3-23 17:36
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitzling a scene from the film “Greg’s Diary” (2010, directed by Thor Freudenthal):A little later, in the same group, Paul (10?years old) remembers a scene from the film “7 Dwarfs” (2004, directed by Sven Unterwaldt):In another group, a girl recalls an everyday scene from her school:Three different circ作者: 削減 時(shí)間: 2025-3-23 20:09 作者: eardrum 時(shí)間: 2025-3-23 23:47 作者: SCORE 時(shí)間: 2025-3-24 03:11 作者: 廣大 時(shí)間: 2025-3-24 08:02
Pharmaceutical Innovation: The Case of Switzerland, similarities in the production processes of both chemical and pharmaceutical substances. Many industry reports aggregate the chemical and the pharmaceutical industries into one single industry called ‘the pharmaceutical-chemical industry’.作者: Progesterone 時(shí)間: 2025-3-24 13:18 作者: 消滅 時(shí)間: 2025-3-24 18:38
Book 20041st edition of drug development at US$ 800 million to US$ 1 billion - per drug! This is equivalent to the price tag of the Empire State Building, when it was for sale a few years ago. In 2001, the major US and European pharmaceutical companies invested more than US$ 30 billion in R&D, at a higher R&D- to-sales作者: adhesive 時(shí)間: 2025-3-24 20:15 作者: DOSE 時(shí)間: 2025-3-25 01:46
The Science and Technology Challenge: How to Find New Drugs, technologies. While innovation activities of established pharmaceutical companies were traditionally based on organic chemistry, biochemistry and chemical engineering, biotechnology companies have built a reputation in many novel areas, such as cell biology, molecular genetics, protein chemistry and encymology (Whittaker, Bower 1994).作者: 勤勉 時(shí)間: 2025-3-25 03:28
Book 20041st editional success. Critical success factors include the discovery phase and a stronger outside-in orientation in the early innovation phase. After the implosion of the high-tech stock mar- ket, biotechnology and other technology-driven opportunities may have lost some of their attractiveness for big pharma作者: Inveterate 時(shí)間: 2025-3-25 09:38 作者: 狂怒 時(shí)間: 2025-3-25 14:57
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitz作者: AORTA 時(shí)間: 2025-3-25 16:49
pages and popular Nigerian blogs. Insights from pragmatics and the linguistic scholarship on humor serve as additional framework. Preliminary investigation shows that the stance of most respondents is hostile or antithetical to that of the online supplicants, whereas there is an alignment between th作者: GULLY 時(shí)間: 2025-3-25 22:43 作者: MERIT 時(shí)間: 2025-3-26 01:57 作者: 致詞 時(shí)間: 2025-3-26 07:24 作者: 直覺沒有 時(shí)間: 2025-3-26 09:25 作者: 我還要背著他 時(shí)間: 2025-3-26 13:35 作者: 徹底明白 時(shí)間: 2025-3-26 19:05
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitzing cinematic tension is already a big challenge, but being funny is, in my experience, incomparably more difficult. The question I therefore asked myself was: how can filmmakers make funny children’s films? But what is funny? What is humour anyway? And what is funny for children? Can such different作者: ALERT 時(shí)間: 2025-3-27 00:09
Oliver Gassmann,Gerrit Reepmeyer,Maximilian von Zedtwitzing cinematic tension is already a big challenge, but being funny is, in my experience, incomparably more difficult. The question I therefore asked myself was: how can filmmakers make funny children’s films? But what is funny? What is humour anyway? And what is funny for children? Can such different作者: Decimate 時(shí)間: 2025-3-27 02:50
https://doi.org/10.1007/978-3-540-24781-4Drug Discovery; Forschung & Entwicklung; Globalization; Innovation Management; Pharmaceuticals; Productiv作者: 透明 時(shí)間: 2025-3-27 08:45
Oliver Gassmann,Gerrit Reepmeyer,Maximilian ZedtwiThe book is based on the three most important challenges in pharmaceutical innovation: productivity dilemma, new technology trends, globalization and outsourcing.Due to the CTO-roundtable with 14 sele作者: Prostaglandins 時(shí)間: 2025-3-27 12:09 作者: gentle 時(shí)間: 2025-3-27 13:48
Springer-Verlag Berlin Heidelberg 2004作者: indubitable 時(shí)間: 2025-3-27 21:51
Innovation as a Key Success Factor in the Pharmaceutical Industry,Despite its high R&D intensity, the pharmaceutical industry is facing an increasingly dire situation. On average, only 1 out of 10′000 substances becomes a marketable product. And only 3 out of 10 drugs generate revenues that meet or exceed average R&D costs (see Reuters 2002).作者: Integrate 時(shí)間: 2025-3-27 22:14
Management Answers to Pharmaceutical R&D Challenges,Time-to-market is extremely important in breakthrough pharmaceuticals: the first in the market captures 40–60% of the market, and the second only around 15%. Coming in behind third means a negative business.作者: evince 時(shí)間: 2025-3-28 04:33 作者: 花爭吵 時(shí)間: 2025-3-28 06:21
9樓作者: MERIT 時(shí)間: 2025-3-28 13:24
10樓作者: 陶器 時(shí)間: 2025-3-28 18:28
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10樓作者: 擔(dān)心 時(shí)間: 2025-3-29 02:29
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