標(biāo)題: Titlebook: Islets of Langerhans; Md. Shahidul Islam Reference work 2015Latest edition Springer Science+Business Media Dordrecht 2015 Beta cells.Diabe [打印本頁(yè)] 作者: 無(wú)緣無(wú)故 時(shí)間: 2025-3-21 16:49
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書(shū)目名稱(chēng)Islets of Langerhans讀者反饋
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作者: Blood-Clot 時(shí)間: 2025-3-21 21:46
https://doi.org/10.1007/978-94-007-6686-0Beta cells; Diabetes; Insulin; Islet transplantation; Islets作者: micronutrients 時(shí)間: 2025-3-22 02:02 作者: Evacuate 時(shí)間: 2025-3-22 06:29 作者: 無(wú)表情 時(shí)間: 2025-3-22 09:21 作者: COMA 時(shí)間: 2025-3-22 15:13 作者: Exhilarate 時(shí)間: 2025-3-22 20:30 作者: 四海為家的人 時(shí)間: 2025-3-22 23:20
Electrophysiology of Islet Cells,. and/or Ca. channels and repolarized by voltage- and/or Ca.-dependent K. channels. At a constant stimulatory glucose concentration, APs are clustered in bursts that are interrupted by hyperpolarized interburst phases. Bursting electrical activity induces parallel fluctuations in [Ca.]. and insulin 作者: 思考而得 時(shí)間: 2025-3-23 02:47
ATP-Sensitive Potassium Channels in Health and Disease,oduce a milder phenotype. Similarly mutations that greatly reduce the ATP sensitivity of the K. channel lead to a severe form of neonatal diabetes with associated neurological complications, while mutations that cause smaller shifts in ATP sensitivity cause neonatal diabetes alone. This chapter revi作者: COLON 時(shí)間: 2025-3-23 09:32
,β Cell Store-Operated Ion Channels,cular mechanisms remain undefined. In this chapter, we provide both an overview of our current understanding of ionic currents regulated by ER Ca. stores in insulin-secreting cells and a review of studies in other cell systems that have identified the molecular basis and regulation of SOCE.作者: osteopath 時(shí)間: 2025-3-23 10:14
,Exocytosis in Islet β-Cells, using the currently available electrophysiological techniques. This chapter provides a concise introduction to the field of optical imaging for those researchers who wish to characterize exocytosis from β-cells in the islets of Langerhans.作者: 一起平行 時(shí)間: 2025-3-23 15:36 作者: Missile 時(shí)間: 2025-3-23 18:12
,High-Fat Programming of β-Cell Dysfunction,bolism of the progeny throughout life. This more recently adopted form of developmental programming reflects society in both affluent and developing countries. High-fat programming induces adverse changes in β-cell development and function in neonatal, weanling, and adolescent progeny. These changes作者: 笨重 時(shí)間: 2025-3-24 01:40
Exercise-Induced Pancreatic Islet Adaptations in Health and Disease,ces β-cell survival is a common outcome in all of the studies. Exercise training-induced alterations on β-cell functions are more controversial. Generally, the studies indicate that in healthy and obese insulin-resistant subjects, exercise decreases nutrient-induced insulin secretion (associated wit作者: Fresco 時(shí)間: 2025-3-24 03:45 作者: 不能妥協(xié) 時(shí)間: 2025-3-24 09:44
Xavier Montet,Smaragda Lamprianou,Laurent Vinet,Paolo Meda,Alfredo Fort作者: 邪惡的你 時(shí)間: 2025-3-24 11:54 作者: 津貼 時(shí)間: 2025-3-24 18:49
Philip Newsholme,Kevin Keane,Celine Gaudel,Neville McClenaghan作者: 防水 時(shí)間: 2025-3-24 21:08 作者: 新字 時(shí)間: 2025-3-25 03:10
Colin A. Leech,Richard F. Kopp,Louis H. Philipson,Michael W. Roe作者: 包租車(chē)船 時(shí)間: 2025-3-25 04:21 作者: 安撫 時(shí)間: 2025-3-25 10:51 作者: cardiac-arrest 時(shí)間: 2025-3-25 14:42 作者: KIN 時(shí)間: 2025-3-25 16:23 作者: 眼界 時(shí)間: 2025-3-25 21:11
Reference work 2015Latest editionadvances made in the respective fields, but also provide directions and thoughts for future research. Thanks to vivid and colorful illustrations, tables and sketches, the book as a whole, and the individual chapters make reading a pleasant experience. If you are interested in diabetes research, you 作者: 圖表證明 時(shí)間: 2025-3-26 04:11 作者: 性上癮 時(shí)間: 2025-3-26 05:55
epth and critical analysis of contemporary islet research.FuThis book contains critical background information, and recent advances made in essentially all areas of islet research. It is a major reference book, the first of its kind, for islet researchers, and diabetes researchers. Anybody, includin作者: 標(biāo)準(zhǔn) 時(shí)間: 2025-3-26 09:42
Physiology and Pathology of the Anomeric Specificity for the Glucose-Induced Secretory Response of y in both diabetic subjects and a number of animal models with altered pancreatic islet status are presented. This review thus represents an updated contribution on the anomeric specificity of the metabolic and functional responses of the three major types of islet endocrine cells to selected hexoses.作者: 可憎 時(shí)間: 2025-3-26 15:25
Anionic Transporters and Channels in Pancreatic Islet Cells, hypothesis, the expression and function of anoctamin 1 in rodent and human pancreatic islet cells, the possible role of bicarbonate-activated soluble adenylyl cyclase, the identity and role of aquaporins in insulin-producing cells, and a proposed role for volume-regulated anion channels in glucagon secretion.作者: 歹徒 時(shí)間: 2025-3-26 20:21 作者: Nonflammable 時(shí)間: 2025-3-26 21:32
Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets,perimental studies that have tested unintuitive predictions of the model and have thereby provided the best evidence to date that oscillations in glycolysis underlie the slow (~5 min) component of electrical, calcium, and metabolic oscillations in mouse islets.作者: 等級(jí)的上升 時(shí)間: 2025-3-27 03:18 作者: Encoding 時(shí)間: 2025-3-27 08:43
The Comparative Anatomy of Islets,overview of the evolution from endocrine cell types in invertebrates to the higher mammals and focus on what has been reported in the literature and some of our own experiences and also include a description of other hormones reported to be found in islets.作者: 緯線(xiàn) 時(shí)間: 2025-3-27 12:49
Basement Membrane in Pancreatic Islet Function,n pancreatic islets. In this chapter, we summarize how the vascular basement membrane influences insulin transcription, insulin secretion, and β-cell proliferation. In addition, a brief overview about basement membrane components and their interactions with cell surface receptors is given.作者: POWER 時(shí)間: 2025-3-27 14:59 作者: 無(wú)意 時(shí)間: 2025-3-27 19:57
,Physiological and Pathophysiological Control of Glucagon Secretion by Pancreatic α-Cells,gon response to hypoglycemia particularly in type 1 diabetes. The reasons of these defects are poorly known. This article presents a short overview of the role of glucagon and the proposed mechanisms of control of glucagon secretion in normal conditions and diabetes and briefly comments the anti-glucagon therapies in diabetes.作者: EWE 時(shí)間: 2025-3-27 22:34
The Comparative Anatomy of Islets,llent comparative work performed in the 1970s and 1980s by the Falkmer, Epple, and Youson groups. What emerges is that islets are much more complex than once thought and show a lot of similarities in rodents and higher primates. The diversity of lifestyles, metabolic demands, and diets has most like作者: Repatriate 時(shí)間: 2025-3-28 05:53 作者: 使厭惡 時(shí)間: 2025-3-28 09:21
Basement Membrane in Pancreatic Islet Function,ost of their essential features, which are insulin production and release. However, the recent discovery of blood vessel/β-cell interactions as an important aspect of insulin transcription, secretion, and proliferation might point us to ways of how this problem could be overcome..The correct functio作者: 蛛絲 時(shí)間: 2025-3-28 14:20
Approaches for Imaging Pancreatic Islets: Recent Advances and Future Prospects,ther in vitro studies or quite indirect in vivo measurements. Methods to noninvasively and repeatedly evaluate the mass and function of β-cells in vivo, two parameters that are central to the study of diabetes, are expected to change our understanding of this disease. However, and in spite of remark作者: Duodenitis 時(shí)間: 2025-3-28 16:39 作者: 清楚 時(shí)間: 2025-3-28 21:23
Regulation of Pancreatic Islet Formation,ysfunction of insulin-producing cells (β-cells) causes diabetes. Generation of β-like cells that can compensate the loss of β-cell mass in type 1 diabetes or defects in β-cell insulin secretion in type 2 diabetes is a current challenge in biomedicine. The knowledge of the molecular basis governing p作者: 地殼 時(shí)間: 2025-3-28 23:51
(Dys)Regulation of Insulin Secretion by Macronutrients,ional neurohormonal signals, in order to secrete insulin to best meet the needs of the organism. β-Cell nutrient sensing requires metabolic activation, resulting in production of stimulus-secretion coupling signals that promote insulin biosynthesis and release. The primary stimulus for insulin secre作者: Tractable 時(shí)間: 2025-3-29 06:06
Physiology and Pathology of the Anomeric Specificity for the Glucose-Induced Secretory Response of mannose. In a physiological perspective, emphasis is placed on the experimental findings documenting such an anomeric specificity and its possible determinants, including consideration on the essential role of the anomeric specificity of phosphoglucoisomerase, phosphomannoisomerase, and phosphogluco作者: Decimate 時(shí)間: 2025-3-29 10:07 作者: tinnitus 時(shí)間: 2025-3-29 12:33
Electrophysiology of Islet Cells,abolism-dependent alterations in ion channel activity..This coupling is best explored in β cells. The effect of glucose is directly linked to mitochondrial metabolism as the ATP/ADP ratio determines the open probability of ATP-sensitive K. channels .K. channels). Nucleotide sensitivity and concentra作者: SEVER 時(shí)間: 2025-3-29 16:38
ATP-Sensitive Potassium Channels in Health and Disease, β-cell is finely balanced; increased activity prevents insulin secretion, whereas reduced activity stimulates insulin release. β-cell metabolism tightly regulates K. channel gating, and if this coupling is perturbed, two distinct disease states can result. Diabetes occurs when the K. channel fails 作者: Meager 時(shí)間: 2025-3-29 23:23 作者: Eructation 時(shí)間: 2025-3-30 03:38 作者: CYN 時(shí)間: 2025-3-30 07:03 作者: 共同給與 時(shí)間: 2025-3-30 11:48
Electrical, Calcium, and Metabolic Oscillations in Pancreatic Islets, bursting. We discuss the underlying mechanisms for bursting oscillations in mouse islets and the parallel oscillations in intracellular calcium and metabolism. We present a unified biophysical model, called the dual oscillator model, in which fast electrical oscillations are due to the feedback of 作者: 補(bǔ)充 時(shí)間: 2025-3-30 14:16
,Exocytosis in Islet β-Cells,tion. Two-photon imaging, in particular, has enabled researchers to visualize the exocytosis of large dense-core vesicles (LDCVs) containing insulin from β-cells in intact islets of Langerhans. These studies have revealed that high glucose levels induce two phases of insulin secretion and that this 作者: BILK 時(shí)間: 2025-3-30 16:49 作者: Abbreviate 時(shí)間: 2025-3-30 23:14
,High-Fat Programming of β-Cell Dysfunction,r insult during critical periods of life which includes fetal and subsequent early neonatal life. Programming alters progeny physiology and metabolism with immediate, transient, and durable effects. Maternal nutrition and metabolic state in gestation and lactation shapes progeny development and heal作者: 不能平靜 時(shí)間: 2025-3-31 02:11 作者: 男學(xué)院 時(shí)間: 2025-3-31 06:28 作者: 侵略者 時(shí)間: 2025-3-31 10:45 作者: Chromatic 時(shí)間: 2025-3-31 13:49
Jürgen Pl?hn energy efficiency, and QoS provisioning. ..This book is a great reference tool for professionals in the field of networking and telecommunications, graduate students and researchers interested in wireless networks, and practitioners working on sensor networks..作者: enflame 時(shí)間: 2025-3-31 19:32 作者: 溫順 時(shí)間: 2025-3-31 22:07 作者: Lymphocyte 時(shí)間: 2025-4-1 04:54 作者: verdict 時(shí)間: 2025-4-1 07:39
Examination of Historical Trends and Future Projections for Climate and Land-use Variables and its he Norwegian Earth System Model (NorESM) was used under two scenarios that included RCP 4.5 and RCP 8.5. The land-use change was simulated using the Land Change Modeler (LCM). Finally, hydrological modeling was done using the Soil and Water Assessment Tool (SWAT) model. The results from NorESM and L作者: 哪有黃油 時(shí)間: 2025-4-1 10:53 作者: Ascendancy 時(shí)間: 2025-4-1 16:48
sional development is also discussed..This book aims to examine how education policies can maximise economic growth and social development. It will be relevant to students and researchers interested in economic development and education economics..978-3-031-20384-8978-3-031-20382-4作者: 警告 時(shí)間: 2025-4-1 21:12 作者: degradation 時(shí)間: 2025-4-1 22:52
nd causes voltage reduction and losses in the distribution network. In current years, the utilization of DG?technologies has extremely inflated worldwide as a result of?their potential?benefits. Optimal sizing and location of DG units near to the load centers provide an effective solution for reduci
