標(biāo)題: Titlebook: Introduction to Basics of Pharmacology and Toxicology; Volume 1: General an Gerard Marshall Raj,Ramasamy Raveendran Book 2019 Springer Natu [打印本頁(yè)] 作者: interleukins 時(shí)間: 2025-3-21 17:04
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作者: 伴隨而來(lái) 時(shí)間: 2025-3-21 20:14 作者: OWL 時(shí)間: 2025-3-22 00:25
The Great Pharmacologists and Their Revolutionary Discoveriesforth by some of the stalwarts in the field of biomedical sciences, who were involved in interdisciplinary research with special inclination towards pharmacology, are worth reviewing. In this chapter, the many doyens in the international arena of pharmacology from Jonathan Pereira (the .) to Louis C作者: 使絕緣 時(shí)間: 2025-3-22 05:31 作者: padding 時(shí)間: 2025-3-22 12:21
Drug Absorption and Bioavailabilityg is directly injected into the systemic circulation. Quantification of the bioavailability by studying the structure and the presence of chemical groups is called Quantitative structure-bioavailability relationship (QSBR). Various novel models have been proposed to improve drug absorption and incre作者: 幼稚 時(shí)間: 2025-3-22 16:12
Drug Distributionon, and slower onset of action. Plasma protein binding is responsible for displacement reactions and drug interactions. Excessive tissue protein binding can result in organ toxicities. To some extent, distribution can be quantified by the apparent volume of distribution. The volume of distribution h作者: 首創(chuàng)精神 時(shí)間: 2025-3-22 17:32
Drug Metabolismorgan metabolizing the drug is important for physician while administering multiple drugs in disease-states like liver and renal failure for the “fine-tuning” of the dose of a drug and avoiding further damage to the failing organ. As various factors like age, gender, food intake, disease status of t作者: chapel 時(shí)間: 2025-3-23 00:00
Mechanisms of Drug Actionresponse. Based on the site at which the drugs act and their intrinsic activity, drugs can interact with each other to cause additive or antagonistic effects. Receptors being stimulated or blocked for a long time undergo downregulation or upregulation, respectively. Various host and drug factors aff作者: Antarctic 時(shí)間: 2025-3-23 01:57 作者: 事物的方面 時(shí)間: 2025-3-23 09:05
Drug Interactionse of the major reasons behind drug interactions. At the level of drug excretion, a drug can affect tubular secretion and reabsorption of other drugs. These interactions can be further classified as additive, synergistic, or antagonistic. In many instances, we have successfully employed drug interact作者: LAY 時(shí)間: 2025-3-23 12:15
Structure-Activity Relationshipstion of “spacer” in the structure of antihistaminic molecules resulted in “nonsedative” antihistaminics. Therefore, SAR plays a vital role in the drug development process which ultimately determines the “success” or “failure” of the drug.作者: venous-leak 時(shí)間: 2025-3-23 14:27
Drug Informationof drug information refer to drug information from pharmaceutical companies or drug manufacturers with the main aim of promoting their drug and increasing the sales of their product. Computerized or electronic information systems and verbal information are the other sources of drug information. Drug作者: 漸強(qiáng) 時(shí)間: 2025-3-23 18:14 作者: Extricate 時(shí)間: 2025-3-24 00:36
Chronopharmacologyvariations have also been observed in various diseases like hypertension, myocardial infarction, bronchial asthma, and cancer. Chronopharmacotherpeutic strategies in optimizing the timing of drug administration have been implemented in various diseases exhibiting circadian variations. Innovative chr作者: DOLT 時(shí)間: 2025-3-24 03:24 作者: tackle 時(shí)間: 2025-3-24 09:54
iversity of Illinois at Urbana-Champaign; Faculty Director of the Odyssey Project; author of Disputing the Subject of Sex: Sexuality and Public School Controversies.Scott Richardson has written a provocative work that lifts the veil and explores a secret space hiding in plain sight in every school i作者: 同音 時(shí)間: 2025-3-24 13:59 作者: HAVOC 時(shí)間: 2025-3-24 18:40 作者: 彩色的蠟筆 時(shí)間: 2025-3-24 20:29
Avinash Arivazhahanlts hold equally in R. and, say, for evolution problems governed by partial differential equations, like the Navier-Stokes equations or equations governing reaction and diffusion in chemical systems, provided the writing of these partial differential equations as evolution problems in Banach space c作者: 傷心 時(shí)間: 2025-3-25 02:10 作者: LAVA 時(shí)間: 2025-3-25 03:29
Abialbon Paulic equilibria. There is a huge literature on static stability of conservative systems which is usually based on minimizing some well-defined energy in the sense of the calculus of variations. The equilibria are defined as critical points of the energy in the sense of the calculus of variations. The 作者: 赦免 時(shí)間: 2025-3-25 11:26 作者: Derogate 時(shí)間: 2025-3-25 11:55
Elavarasi Pichai,Mageshwaran Lakshmanant a range of mathematical levels. It is essential for the reader to work through the numerical exercises, for only in this way can he grasp the full meaning and usefulness of the statistical techniques, and gain practice in the interpretation of the results. Chapters 7 and 8 discuss methods appropriate for us978-94-009-5958-3作者: 從容 時(shí)間: 2025-3-25 17:05 作者: 提名的名單 時(shí)間: 2025-3-25 22:38
Rekha Priyadarshiniution, which is defined by statistical concepts like mean, variance, skewness, kurtosis, etc. They are defined by a mathematical function which is used to estimate various probabilities. Normal distribution is the most important and used distribution, which has applications in many areas.作者: COST 時(shí)間: 2025-3-26 01:44 作者: 壯觀的游行 時(shí)間: 2025-3-26 04:38
Heta Shah,Neel Jayesh Shah a range of mathematical levels. It is essential for the reader to work through the numerical exercises, for only in this way can he grasp the full meaning and usefulness of the statistical techniques, and gain practice in the interpretation of the results. Chapters 7 and 8 discuss methods appropriate for use978-0-412-11370-3978-1-4899-3288-4作者: 喊叫 時(shí)間: 2025-3-26 11:41 作者: 浪費(fèi)物質(zhì) 時(shí)間: 2025-3-26 13:01
a less to a more probable state. The conclusion is inevitable that there ought to be some connection between entropy and probability. We are thus led to examine the subject of probability and, in turn, enquire how one can determine which of a great many possible states is the most probable one. We 作者: 絕緣 時(shí)間: 2025-3-26 17:11 作者: VERT 時(shí)間: 2025-3-26 23:21
Book 2019nce, and the use of molecular biology techniques in pharmacology.?The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.?.作者: Proclaim 時(shí)間: 2025-3-27 01:17
Gerard Marshall Raj Project; author of Disputing the Subject of Sex: Sexuality and Public School Controversies.Scott Richardson has written a provocative work that lifts the veil and explores a secret space hiding in plain sight in every school i978-94-6209-001-9作者: cuticle 時(shí)間: 2025-3-27 06:22
Project; author of Disputing the Subject of Sex: Sexuality and Public School Controversies.Scott Richardson has written a provocative work that lifts the veil and explores a secret space hiding in plain sight in every school i978-94-6209-001-9作者: Admonish 時(shí)間: 2025-3-27 12:22 作者: 策略 時(shí)間: 2025-3-27 14:51 作者: Offstage 時(shí)間: 2025-3-27 21:02
Nishanthi Anandabaskarf Poincaré‘s last geometric theorem and the Arnol‘d conjecture are introduced. In Chapter 7 elements of the global asymptotic treatment of the highly oscillatin978-3-319-11025-7978-3-319-11026-4Series ISSN 1862-9113 Series E-ISSN 1862-9121 作者: 難理解 時(shí)間: 2025-3-28 00:23 作者: 揭穿真相 時(shí)間: 2025-3-28 02:51 作者: 世俗 時(shí)間: 2025-3-28 08:23 作者: ADAGE 時(shí)間: 2025-3-28 13:50
http://image.papertrans.cn/i/image/473458.jpg作者: faucet 時(shí)間: 2025-3-28 16:57 作者: RENIN 時(shí)間: 2025-3-28 22:39
Sources and Nature of Drugsto man. The nature of drugs relates to the physical or chemical properties of drugs, in general. These properties including drug matter, drug size, drug shape and drug bonds, and others are also explained in brief at the end of this chapter.作者: 徹底檢查 時(shí)間: 2025-3-29 02:12
Drug Eliminationetion resulting in toxicity or failure of therapy. Elimination of drugs in breast milk is a major concern while prescribing the drug for lactating mother. In clinics, the knowledge about the drug elimination gains significance in multidrug therapy, in the presence of organ failure and other co-morbid conditions.作者: N斯巴達(dá)人 時(shí)間: 2025-3-29 04:57
Principles and Modes of Drug Administrationecialized routes and modes of drug delivery, like the liposomal delivery, prodrug delivery and others. Each of these routes of administration has its own pros and cons, which have to be weighed against each other before choosing the same. This chapter deals about the key principles and routes or modes of drug administration.作者: 盡忠 時(shí)間: 2025-3-29 10:45 作者: 不確定 時(shí)間: 2025-3-29 12:37
.Covers special topics in pharmacology that are hard to find.This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureat作者: Protein 時(shí)間: 2025-3-29 17:52
The Great Pharmacologists and Their Revolutionary Discoveries chemistry, the drastic growth in the branch of pharmacology as a medical speciality was very much perceptible. The domain of pharmacology, as an independent speciality, in the last century-and-half, has transformed from the usage of crude plant extracts as drugs to the more synthetically engineered作者: 流浪者 時(shí)間: 2025-3-29 23:36 作者: Ornament 時(shí)間: 2025-3-30 02:56 作者: 噱頭 時(shí)間: 2025-3-30 06:22
Principles and Modes of Drug Administrationinically relevant in therapeutics, and helps in avoiding any potential harm to patients receiving these drugs. While there are several principles of drug administration, the five important ones are: the right patient, the right drug, the right dose, the right time and the right route of administrati作者: promote 時(shí)間: 2025-3-30 08:37
Drug Absorption and Bioavailability absorption of drugs. They include passive diffusion, facilitated diffusion, active transport, and endocytosis. Drug absorption is quantified in terms of bioavailability. Bioavailability is the extent to which absorption occurs. In other words, bioavailability is the fraction of the administered dru作者: 禁令 時(shí)間: 2025-3-30 14:06
Drug Distributionstribution. Distribution is an important process which results in exposure of the target organ to the drug. The initial phase is highly influenced by the amount of blood flow to various organs and is responsible for the acute onset action of the drugs. The second phase is a slower phase where the dr作者: esthetician 時(shí)間: 2025-3-30 17:48
Drug Metabolismoccur predominantly in the liver and kidney with a minor contribution from the GI tract, lungs, skin, and plasma. In the liver, the cytochrome P450 enzymes play a major role in the metabolism of drugs and have a significant role in “drug interaction” due to enzyme induction and inhibition during mul作者: Intentional 時(shí)間: 2025-3-30 22:43
Drug Eliminationf the drug. The major route of drug elimination is kidney, followed by the liver, lungs, skin, salivary glands, mammary glands, and semen constituting the nonrenal pathways for drug elimination. Size, solubility, polarity, and protein binding nature are the major determinants for the elimination of 作者: 涂掉 時(shí)間: 2025-3-31 03:34
Mechanisms of Drug Actioneptions, the general rule is that drugs do not work unless they bind to a receptor. A receptor is a cellular component that the drugs bind to and produce cellular action. Receptors can either be signal-transducing extracellular entities, ion channels, intracellular enzymes or intranuclear targets. D作者: 粗糙濫制 時(shí)間: 2025-3-31 07:40
Drug Transporters environmental toxins. Drug transporters are also involved in the regulation of drug distribution and their bioavailability, transport of compounds across the blood-brain barrier, and hematopoietic stem cell protection from toxins. Functionally, they are classified as influx and efflux transporters.作者: extinct 時(shí)間: 2025-3-31 10:31
