標(biāo)題: Titlebook: Innovative Antimetabolites in Solid Tumours; Matti S. Aapro Conference proceedings 1994 Springer-Verlag Berlin Heidelberg 1994 Antimetabol [打印本頁(yè)] 作者: ACID 時(shí)間: 2025-3-21 17:14
書(shū)目名稱Innovative Antimetabolites in Solid Tumours影響因子(影響力)
書(shū)目名稱Innovative Antimetabolites in Solid Tumours影響因子(影響力)學(xué)科排名
書(shū)目名稱Innovative Antimetabolites in Solid Tumours網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Innovative Antimetabolites in Solid Tumours網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Innovative Antimetabolites in Solid Tumours被引頻次
書(shū)目名稱Innovative Antimetabolites in Solid Tumours被引頻次學(xué)科排名
書(shū)目名稱Innovative Antimetabolites in Solid Tumours年度引用
書(shū)目名稱Innovative Antimetabolites in Solid Tumours年度引用學(xué)科排名
書(shū)目名稱Innovative Antimetabolites in Solid Tumours讀者反饋
書(shū)目名稱Innovative Antimetabolites in Solid Tumours讀者反饋學(xué)科排名
作者: GOAD 時(shí)間: 2025-3-21 20:20 作者: reptile 時(shí)間: 2025-3-22 02:32
Thymidylate Synthase Inhibitors, Modulation of 5-Fluorouracil and Folate Analogues,to clinical practice. The effects of 5-fluorouracil on the cell are 1) inhibition of thymidylate synthase, 2) a direct effect on DNA, and 3) a direct effect on RNA [1]. These mechanisms and their modulation by other factors designed to increase activation, response rates and survival, will be discus作者: Gratulate 時(shí)間: 2025-3-22 07:58
A Review of Fludarabine and Cladribine in Solid Tumours,ancies such as hairy cell leukaemia, low-grade non-Hodgkin’s lymphoma, chronic lymphocytic leukaemia, Waldenstr?m macroglobulinaemia and cutaneous T-cell lymphoma [1,2]. Both have also been used in acute leukaemias and fludarabine appears particularly promising for this indication [3]. Activation of作者: 山崩 時(shí)間: 2025-3-22 10:04
Gemcitabine in Ovarian Cancer,dard practice. It is obvious that new drugs are needed to improve the results in advanced disease. Recently the introduction of taxanes in the treatment of ovarian cancer has engendered hope that treatment may further improve. Gemcitabine is another promising candidate to be added to the list of dru作者: 發(fā)牢騷 時(shí)間: 2025-3-22 14:48
Gemcitabine Therapy in Non-Small Cell Lung Cancer: A Review,last decade. Few single agents have, in large studies, achieved response rates of more than 15%, while combination treatment gives response rates of 25% to 35% [1–4]. Several randomised studies comparing chemotherapy with best supportive care have yielded predominantly slightly favourable results fo作者: DUCE 時(shí)間: 2025-3-22 17:39 作者: Deduct 時(shí)間: 2025-3-23 00:14 作者: BILK 時(shí)間: 2025-3-23 03:06 作者: 鑲嵌細(xì)工 時(shí)間: 2025-3-23 09:15
A Review of Fludarabine and Cladribine in Solid Tumours,nce between activation and degradation appears crucial for their clinical activity [4]. FAMP and CDA are cytotoxic not by inducing necrosis but rather programmed cell death, apoptosis, by means of activation of specific endonucleases [5].作者: 生銹 時(shí)間: 2025-3-23 12:37
is and treatment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated作者: Reverie 時(shí)間: 2025-3-23 16:21
Gemcitabine in Ovarian Cancer,gs active in ovarian cancer. The drug showed activity in a group of patients not very likely to respond. In this review we will first discuss the factors that determine the outcome of phase II studies, such as the initial treatment and previous second-line treatment, and then we will take a closer look at the results obtained with gemcitabine.作者: Ordeal 時(shí)間: 2025-3-23 19:44
Gemcitabine Therapy in Non-Small Cell Lung Cancer: A Review,r chemotherapy [5]. Two recent meta-analyses of the literature indicated a significant but modest survival advantage for the use of platinum-containing combination treatment compared with best supportive care [6,7].作者: Budget 時(shí)間: 2025-3-23 22:18
Preclinical Characteristics of Cytarabine, Gemcitabine, Fludarabine and Cladribine: Relevance for C Their biological activity is due to the fact that most nucleoside analogues are targeted at DNA synthesis, an essential function both for cellular replication and for the repair of DNA damage that may be caused by other agents.作者: otic-capsule 時(shí)間: 2025-3-24 05:59
Conference proceedings 1994atment of cancer. There are two main reasons why such an initiative was considered necessary. Firstly, the teaching of oncology requires a rigorously multidisciplinary approach which is difficult for the Universities to put into practice since their system is mainly disciplinary orientated. Secondly作者: palpitate 時(shí)間: 2025-3-24 10:01
https://doi.org/10.1007/978-3-642-79200-7Antimetabolit; Antimetabolite; Antimetabolites; Cladribin; Onkologie; breast cancer; cancer; cancer treatme作者: 否決 時(shí)間: 2025-3-24 11:51
Antimetabolites: Historical Perspectives,Antimetabolites are structural analogues of normal metabolites that are required for cell functions and replication. As such and in order to inhibit DNA biosynthesis, they interact with enzymes in 3 different ways:作者: jaundiced 時(shí)間: 2025-3-24 15:09 作者: growth-factor 時(shí)間: 2025-3-24 19:14 作者: Adenocarcinoma 時(shí)間: 2025-3-25 03:09 作者: cardiac-arrest 時(shí)間: 2025-3-25 05:28
978-3-642-79202-1Springer-Verlag Berlin Heidelberg 1994作者: Pde5-Inhibitors 時(shí)間: 2025-3-25 10:29
Introduction,lmost half a century has elapsed since Farber published the demonstration of efficacy of aminopterin in childhood acute leukaemia. Maybe antimetabolites should be called the “aspirin” of oncology, as they share a long-standing history and are continuously rediscovered as a class of agents.作者: freight 時(shí)間: 2025-3-25 12:41
Thymidylate Synthase Inhibitors, Modulation of 5-Fluorouracil and Folate Analogues,to clinical practice. The effects of 5-fluorouracil on the cell are 1) inhibition of thymidylate synthase, 2) a direct effect on DNA, and 3) a direct effect on RNA [1]. These mechanisms and their modulation by other factors designed to increase activation, response rates and survival, will be discussed in this chapter.作者: 粉筆 時(shí)間: 2025-3-25 16:07
Chemotherapy in Advanced Non-Small Cell Lung Cancer. Changes in Performance Status and Tumour-Relatalistic possibility of increasing survival. The problem is that relatively few active agents have been identified. Many earlier studies also involved combinations of drugs with minimal antitumour effect. It is not surprising therefore that chemotherapy of NSCLC was and still is considered by some to be of little or of no value.作者: STELL 時(shí)間: 2025-3-25 22:37
Conference proceedings 1994erapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been作者: LURE 時(shí)間: 2025-3-26 01:01
nt chemotherapy, radiotherapy alone or integrated), it is the ambition of the European School of Oncology to fill a cultural and scientific gap and, thereby, create a bridge between the University and Industry and between these two and daily medical practice. One of the more recent initiatives of ESO has been978-3-642-79202-1978-3-642-79200-7作者: UTTER 時(shí)間: 2025-3-26 06:05 作者: Firefly 時(shí)間: 2025-3-26 10:32 作者: 頌揚(yáng)本人 時(shí)間: 2025-3-26 13:20
Peter Harper,Hilary Calvertersuchen zeigte, bei weitem die wichtigste Bedeutung für das Zustandekommen dieser Blutverschiebungen im K?rper haben, so war es doch von gro?em Wert, die Ergebnisse der Anwendung der Methode des ?inneren Plethysmographen“ durch Benutzung einer ganz anderen Untersuchungsart kontrollieren zu k?nnen. 作者: 鋼筆尖 時(shí)間: 2025-3-26 17:34
Distinguishing Artifactual Fatty Acid Dimers from Fatty Acid Esters of Hydroxy Fatty Acids in Untargpplying liquid chromatography (LC) and mass spectrometry (MS)-based methods are widely used to survey a broad range of metabolites within various metabolic pathways, including organic acids, amino acids, nucleosides, and lipids. Accurate and complete identification of putative metabolites is an ongo作者: champaign 時(shí)間: 2025-3-26 23:38
Role of Cytokines in the Management of Chronic Lymphocytic Leukemia Cancer Society is for approx 7000 new cases in the United States in 2003. (This number suggests an apparent decline in incidence, but it may reflect an increased ability to distinguish CLL from other chronic lymphoid leukemias ..) CLL tends to be a disease of the elderly; the median age at diagnosi作者: 極微小 時(shí)間: 2025-3-27 04:33 作者: Malcontent 時(shí)間: 2025-3-27 07:52
Signal Selection for Visibility Enhancement,cause, if we select the right signals to trace so that a bug leaves “evidences” on them, finding the root cause for the bug would be quite easy. Otherwise, the debug process can be quite challenging. In current practice, designers . select those signals that are considered to be vulnerable to bugs o作者: 歌劇等 時(shí)間: 2025-3-27 10:36 作者: Expand 時(shí)間: 2025-3-27 13:50
Von der Aufruhrsteuer bis zum Zehnten fuzzy intervals are simply introduced to give a meaning to the fuzzy propositions issued from the knowledge base. Finally, it is shown how possibility measures can be used to assign different types to patients after examination of their condition.作者: Grating 時(shí)間: 2025-3-27 19:35
Propositions of Value for the Customer in Insurance 4.0,can leverage insurance 4.0 solutions to deliver disruptive products and services to the market, to achieve a competitive advantage. The fundamental statement of this chapter is that insuring is necessary, insurance is not.作者: 分期付款 時(shí)間: 2025-3-28 01:48
Risk-adjusted or risk-free imputation rate?column bed. In contrast, liquid flow in a fluidized bed is upward and the resulting force causes the bed to expand, making spaces between adsorbent particles. The loosely suspended adsorbent particles shown in . allow the unimpeded passage of fluids through the column bed.作者: 榮幸 時(shí)間: 2025-3-28 05:17 作者: mosque 時(shí)間: 2025-3-28 08:47
LOX-1 and Immunitying a novel role of LOX-1 in immunity. LOX-1 and other pattern recognition receptors are expressed on the surface of myeloid cells like macrophages, dendritic cells, or neutrophils. They have an important role in the immediate innate immune response and also in the regulation of the adaptive immune 作者: 現(xiàn)存 時(shí)間: 2025-3-28 12:46 作者: maverick 時(shí)間: 2025-3-28 16:20 作者: 減少 時(shí)間: 2025-3-28 22:29
Mathematical Engineeringhttp://image.papertrans.cn/s/image/877942.jpg作者: harmony 時(shí)間: 2025-3-29 01:44
How Sceptical Is Hume’s Theory of Personal Identity?undle theory or with his scepticism concerning personal identity. The Appendix, rather, is designed to clarify and strengthen Hume’s scepticism: after publishing Book I of the . Hume realises that there is not only no positive?evidence for realist accounts of personal identity, but that, given two p
