標(biāo)題: Titlebook: Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design; Sanjeev Kumar Singh Book 2021 Springe [打印本頁] 作者: Carter 時(shí)間: 2025-3-21 16:20
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作者: Mercantile 時(shí)間: 2025-3-21 20:33 作者: oncologist 時(shí)間: 2025-3-22 04:12 作者: Compassionate 時(shí)間: 2025-3-22 07:47 作者: 脫水 時(shí)間: 2025-3-22 10:48
the exogenous addition of low mM levels of three distinct 5 carbon chain carboxylic acids: α-keto glutarate, glutamate, and glutamine. Activation of CFTR by these substances alone induces a Cl. permeable, HCO. . impermeable state in this tissue that is comparable in magnitude to that elicited by cla作者: Alpha-Cells 時(shí)間: 2025-3-22 16:40
Ankita Singh,Shashank Shekhar,B. Jayaramthe exogenous addition of low mM levels of three distinct 5 carbon chain carboxylic acids: α-keto glutarate, glutamate, and glutamine. Activation of CFTR by these substances alone induces a Cl. permeable, HCO. . impermeable state in this tissue that is comparable in magnitude to that elicited by cla作者: 經(jīng)典 時(shí)間: 2025-3-22 20:04
Sunita Gupta,Mohd. Waseem,Naveen Kumar Meena,Roopa Kuntal,Andrew M. Lynn,Smriti Mishrathe exogenous addition of low mM levels of three distinct 5 carbon chain carboxylic acids: α-keto glutarate, glutamate, and glutamine. Activation of CFTR by these substances alone induces a Cl. permeable, HCO. . impermeable state in this tissue that is comparable in magnitude to that elicited by cla作者: arousal 時(shí)間: 2025-3-22 22:11 作者: 多產(chǎn)魚 時(shí)間: 2025-3-23 02:52 作者: 無價(jià)值 時(shí)間: 2025-3-23 06:33 作者: Unsaturated-Fat 時(shí)間: 2025-3-23 12:44 作者: 知識(shí) 時(shí)間: 2025-3-23 15:07
Ishwar Chandra,Chirasmita Nayak,Sanjeev Kumar Singhdifferent quenched and tempered specimens of SAE 4140. In the initial stage of cyclic loading, normalized specimens exhibit quasi elastic behavior followed by inhomogeneous work-softening effects. After reaching a maximum plastic strain amplitude, a work-hardening period follows with homogeneous pla作者: 本能 時(shí)間: 2025-3-23 21:38 作者: FADE 時(shí)間: 2025-3-23 22:58
Nipanshu Agarwal,Vivek Chetry,Krishna Mohan Polurien-sile and cyclic deformation in an electron microscope. The results show a number of new findings regarding the dislocation behavior near the crack tip and its relationship to the propagation of cracks. Depending on the loading geometry, it was possible to observe the propagation of shear cracks o作者: 有危險(xiǎn) 時(shí)間: 2025-3-24 06:24 作者: Culmination 時(shí)間: 2025-3-24 10:35 作者: chisel 時(shí)間: 2025-3-24 13:32
Rohit Shukla,Timir Tripathilt das Interesse in den 50er und 60er Jahren den strukturellen Erfordernissen der Entwicklung zur Demokratie (Lipset 1959: ?prerequisites“), so richtete sich die Aufmerksamkeit im folgenden Jahrzehnt auf die Frage nach den Ursachen für den ?Breakdown of Democracies“ (Linz/Stepan 1978). Eine weitere 作者: debouch 時(shí)間: 2025-3-24 15:29
Prateek Kumar,Nitin Sharma,Amit Kumar,Rajanish Girieople who interact, (2) Panic as an individual psychiatric or psychological problem which is present: (a) in persons with previous panic disorder, or (b) in persons without previous panic disorder... It is well known fact that humans are vulnerable to high intensity emotions like panic. Panic is oft作者: Chameleon 時(shí)間: 2025-3-24 21:59 作者: 并置 時(shí)間: 2025-3-25 00:59 作者: JOT 時(shí)間: 2025-3-25 06:32 作者: interrogate 時(shí)間: 2025-3-25 07:39
Role of Advanced Computing in the Drug Discovery Process,dvent of advanced computing techniques such as artificial intelligence and high-performance computing, the problems of the traditional drug discovery approach can be circumvented. In particular, computational approaches help in analyzing and locating active binding sites and guide towards the select作者: 仔細(xì)檢查 時(shí)間: 2025-3-25 15:15
Protein Structure, Dynamics and Assembly: Implications for Drug Discovery,electrostatic fingerprints of the functional site of a target protein so that they can bind to the protein and impede its molecular function. Details of functional site are derived from 3-D structure of the protein obtained either through experimental techniques or computational protein modeling and作者: 廣口瓶 時(shí)間: 2025-3-25 19:28 作者: Receive 時(shí)間: 2025-3-25 23:29 作者: oblique 時(shí)間: 2025-3-26 00:18
Magnitude and Advancements of CADD in Identifying Therapeutic Intervention against Flaviviruses,ugh the allegation of life threatening diseases with strident risk to death. Every year, people around the globe reports for the victim of various diseases like Dengue fever, Yellow fever, Encephalitis, Microcephaly and other neurological implications with the dominance of flaviviruses. Flaviviruses作者: 心胸開闊 時(shí)間: 2025-3-26 06:58
Elucidating Protein-Ligand Interactions Using High Throughput Biophysical Techniques,n cell physiology, their interaction with small molecules that modulates the function are clinically significant. Nearly, all essential biomolecular processes are highly sensitive and selective involving molecular recognition and binding of ligands/macromolecules to proteins. Hence, techniques that 作者: 雪崩 時(shí)間: 2025-3-26 08:35
In Silico Approach in Drug Design and Drug Discovery: An Update,and time-consuming which demands hard work. The in silico approach has become indispensible for the drug discovery process. The in silico methods have been proved beneficial in the estimation of biological activities of chemical compounds against a target. Moreover, it has been used to examine the b作者: contradict 時(shí)間: 2025-3-26 16:04 作者: TAG 時(shí)間: 2025-3-26 17:52 作者: 廚房里面 時(shí)間: 2025-3-26 20:58 作者: nerve-sparing 時(shí)間: 2025-3-27 02:25 作者: Assault 時(shí)間: 2025-3-27 06:43 作者: Urgency 時(shí)間: 2025-3-27 13:06
Sunita Gupta,Mohd. Waseem,Naveen Kumar Meena,Roopa Kuntal,Andrew M. Lynn,Smriti Mishrat on ATP hydrolysis. Evidence that these responses are properties of CFTR is derived from tissues from cystic fibrosis patients that show CFTR mutation (genotype) specific responses. The physiological role of glutamate activation remains to be defined, but we speculate that it may involve controls o作者: cardiac-arrest 時(shí)間: 2025-3-27 13:36
Daliah Michael,Namrata Bankoti,Ansuman Biswas,K. Sekareutic aspects of secretion disorders relevant in cystic fibrosis and related diseases...This book will be of interest to Molecular biologists, physiologists, scientists working in pharmaceutical research and drug developement, physicians and researchers in Cystic fibrosis and related diseases..978-1-4614-9839-1978-0-387-23250-8作者: bioavailability 時(shí)間: 2025-3-27 19:47 作者: Palatial 時(shí)間: 2025-3-27 22:09
Arangasamy Yazhini,Sohini Chakraborti,Narayanaswamy Srinivasant on ATP hydrolysis. Evidence that these responses are properties of CFTR is derived from tissues from cystic fibrosis patients that show CFTR mutation (genotype) specific responses. The physiological role of glutamate activation remains to be defined, but we speculate that it may involve controls o作者: accomplishment 時(shí)間: 2025-3-28 03:35 作者: STALE 時(shí)間: 2025-3-28 07:30 作者: landmark 時(shí)間: 2025-3-28 13:56
Murali Aarthy,Umesh Panwar,Sanjeev Kumar Singh crack tip on planes which were inclined to crack. As the dislocations were emitted, the crack tip was blunted and crack propagation ceased. Under cyclic loading conditions, some of the dislocations near the crack tip reversed their direction and returned to the crack tip and disappeared as the stre作者: 書法 時(shí)間: 2025-3-28 14:46
Nipanshu Agarwal,Vivek Chetry,Krishna Mohan Poluri crack tip on planes which were inclined to crack. As the dislocations were emitted, the crack tip was blunted and crack propagation ceased. Under cyclic loading conditions, some of the dislocations near the crack tip reversed their direction and returned to the crack tip and disappeared as the stre作者: Affable 時(shí)間: 2025-3-28 22:26 作者: 作嘔 時(shí)間: 2025-3-29 01:25
Neha Raina,Amit Kumar Singh,Asimul Islamuf vielfach registrierte Defizite der einzelnen Theorieans?tze das pragmatische Eingest?ndnis, dass es sinnvoller ist, die M?glichkeiten eines komplement?ren Einsatzes unterschiedlicher Theorieans?tze auszuloten, als einem K?nigsweg der Transformationsforschung nachzuspüren..作者: 控制 時(shí)間: 2025-3-29 06:03 作者: 有花 時(shí)間: 2025-3-29 09:40
Prateek Kumar,Nitin Sharma,Amit Kumar,Rajanish Girittack; (2) panic disorder and (3) phobia as the consequence of panic... One of the possible targets of this objective is to produce panic in vulnerable subgroups of people with expectation that they will spread it through population. Persons with anxiety disorders, especially persons with panic diso作者: 有說服力 時(shí)間: 2025-3-29 13:47 作者: 生氣地 時(shí)間: 2025-3-29 17:25
Recent Trends in Computer-Aided Drug Design,n of all the known metabolic pathways in the above three categories. The entire approach was designed to identify a potential target that plays an essential role in the pathogen’s survival and constitutes a critical component in its metabolic pathway. The second case study describes various steps in作者: 不連貫 時(shí)間: 2025-3-29 20:02
Predicting Protein Folding and Protein Stability by Molecular Dynamics Simulations for Computationa pragmatic and worthy. This chapter illustrates about computational protein structure prediction and different MDS methods to unveil protein folding. Significance of MDS studies on assessment of protein stability and computational drug discovery has been also summarized.作者: Medicare 時(shí)間: 2025-3-30 00:38 作者: CAMEO 時(shí)間: 2025-3-30 06:04
Elucidating Protein-Ligand Interactions Using High Throughput Biophysical Techniques,rface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC) and Fluorescence Spectroscopy that are vastly used in characterizing the thermodynamics and kinetics of protein-ligand interaction.作者: 召集 時(shí)間: 2025-3-30 09:23
Biological Implications of Polyethylene Glycol and PEGylation: Therapeutic Approaches Based on Biopc interactions with nucleic acids. Many PEG-enzymes conjugates have already obtained FDA approval for clinical implications. PEGylated copolymers have least cytotoxicity and cell-compatibility concern, high efficiency, safety and biocompatibility and thus considered as an attractive polymer for gene作者: arthroscopy 時(shí)間: 2025-3-30 15:31 作者: multiply 時(shí)間: 2025-3-30 16:53
Innovations and Implementations of Computer Aided Drug Discovery Strategies in Rational Drug Design
