標(biāo)題: Titlebook: Innate DNA and RNA Recognition; Methods and Protocol Hans-Joachim Anders,Adriana Migliorini Book 2014 Springer Science+Business Media New Y [打印本頁] 作者: Kennedy 時(shí)間: 2025-3-21 17:03
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書目名稱Innate DNA and RNA Recognition讀者反饋學(xué)科排名
作者: 替代品 時(shí)間: 2025-3-21 21:28
1064-3745 ation advice from the experts.Innate DNA and RNA Recognition: Method and Protocols. presents validated experimental strategies to dissect nucleic acid sensing in-vitro and in-vivo sources. Written in the highly successful .Methods in Molecular Biology. series format, chapters include introductions t作者: Hypopnea 時(shí)間: 2025-3-22 01:30
Detection of RNA Modifications by HPLC Analysis and Competitive ELISAge can lead to random modifications in rRNA and messenger RNA (mRNA) that strongly impair functionality. RNA modifications have also been implicated in avoiding self-RNA recognition by the immune system or immune evasion by pathogens. Here, we describe the detection of RNA modifications by HPLC analysis and competitive ELISA.作者: 耕種 時(shí)間: 2025-3-22 08:33 作者: ingenue 時(shí)間: 2025-3-22 09:56
Analysis of Nucleic Acid-Induced Nonimmune Cell Death In Vitroo cell death. Here, we describe reliable and simple methods to quantify cell death caused by nucleic acid recognition. Additionally, we report two different methods to discriminate between two cell death modalities: apoptosis and necrosis.作者: infantile 時(shí)間: 2025-3-22 15:11
Isolation of Intratumoral Leukocytes of TLR-Stimulated Tumor-Bearing Miceysis (e.g., by flow cytometry) or cultured for functional in vitro studies. Here, we describe the isolation of intratumoral leukocytes by density gradient centrifugation. This technique can be used to isolate leukocytes from freshly dissected murine tumors.作者: medieval 時(shí)間: 2025-3-22 18:03 作者: 橫截,橫斷 時(shí)間: 2025-3-23 01:17 作者: ORBIT 時(shí)間: 2025-3-23 05:24 作者: 史前 時(shí)間: 2025-3-23 07:03
Viral Nucleic Acid Recognition in Human Nonimmune Cells: In Vitro Systemsemplify two viral infection models using cultured nonimmune cells and hepatitis C virus (HCV) or polyomavirus BK (BKV). In addition, we report the importance of siRNA technique in gene regulation in order to identify specific markers involved in innate antiviral responses in these cells.作者: AROMA 時(shí)間: 2025-3-23 11:25
ailable in one place, and many are not even available in anyThis book grew out of an attempt to describe a variety of tools that were developed over a period of years in IBM to analyze Integrated Circuit fail data. The selection presented in this book focuses on those tools that have a significant s作者: 織物 時(shí)間: 2025-3-23 14:17
Gernot Nees,Andreas Kaufmann,Stefan Bauerailable in one place, and many are not even available in anyThis book grew out of an attempt to describe a variety of tools that were developed over a period of years in IBM to analyze Integrated Circuit fail data. The selection presented in this book focuses on those tools that have a significant s作者: TIA742 時(shí)間: 2025-3-23 21:25 作者: emulsify 時(shí)間: 2025-3-24 01:49
Filiz Civril,Karl-Peter Hopfnerailable in one place, and many are not even available in anyThis book grew out of an attempt to describe a variety of tools that were developed over a period of years in IBM to analyze Integrated Circuit fail data. The selection presented in this book focuses on those tools that have a significant s作者: 鴕鳥 時(shí)間: 2025-3-24 04:43 作者: 宴會(huì) 時(shí)間: 2025-3-24 08:28 作者: 大方一點(diǎn) 時(shí)間: 2025-3-24 13:21 作者: ligature 時(shí)間: 2025-3-24 17:34 作者: STELL 時(shí)間: 2025-3-24 21:01 作者: 事先無準(zhǔn)備 時(shí)間: 2025-3-24 23:21 作者: Cabg318 時(shí)間: 2025-3-25 07:13 作者: champaign 時(shí)間: 2025-3-25 09:36
Viktor H. Koelzer,David Anzailable in one place, and many are not even available in anyThis book grew out of an attempt to describe a variety of tools that were developed over a period of years in IBM to analyze Integrated Circuit fail data. The selection presented in this book focuses on those tools that have a significant s作者: Climate 時(shí)間: 2025-3-25 11:48
Theresa Kaeuferle,Sabine Bartel,Stefan Dehmel,Susanne Krauss-Etschmannailable in one place, and many are not even available in anyThis book grew out of an attempt to describe a variety of tools that were developed over a period of years in IBM to analyze Integrated Circuit fail data. The selection presented in this book focuses on those tools that have a significant s作者: 清楚說話 時(shí)間: 2025-3-25 18:58 作者: IOTA 時(shí)間: 2025-3-25 20:23
Maciej Lech,Hans-Joachim Andersthmic descriptions are detailed so the reader can understand.Data Mining and Knowledge Discovery Handbook. organizes all major concepts, theories, methodologies, trends, challenges and applications of data mining (DM) and knowledge discovery in databases (KDD) into a coherent and unified repository.作者: TOM 時(shí)間: 2025-3-26 01:29
Amanda A. Watkins,Ramon G. B. Bonegio,Ian R. Rifkinthmic descriptions are detailed so the reader can understand.Data Mining and Knowledge Discovery Handbook. organizes all major concepts, theories, methodologies, trends, challenges and applications of data mining (DM) and knowledge discovery in databases (KDD) into a coherent and unified repository.作者: Amendment 時(shí)間: 2025-3-26 08:01
John M. Hoppe,Volker Vielhauertors, who are experts in this field.New case studies introdu.Knowledge Discovery demonstrates intelligent computing at its best, and is the most desirable and interesting end-product of Information Technology. To be able to discover and to extract knowledge from data is a task that many researchers 作者: 燈絲 時(shí)間: 2025-3-26 09:20
Moritz Rapp,David Anz,Max SchnurrTo be able to discover and to extract knowledge from data is a task that many researchers and practitioners are endeavoring to accomplish. There is a lot of hidden knowledge waiting to be discovered – this is the challenge created by today’s abundance of data..Data Mining and Knowledge Discovery Han作者: Fulsome 時(shí)間: 2025-3-26 12:45 作者: Nonconformist 時(shí)間: 2025-3-26 19:24
Detection of RNA Modifications by HPLC Analysis and Competitive ELISA and transfer RNA (tRNA) exhibit the most and diverse modifications that presumably optimize their structure and function. In contrast, oxidative damage can lead to random modifications in rRNA and messenger RNA (mRNA) that strongly impair functionality. RNA modifications have also been implicated i作者: 小卷發(fā) 時(shí)間: 2025-3-27 00:18 作者: miniature 時(shí)間: 2025-3-27 03:24
Crystallization of Mouse RIG-I ATPase Domain: In Situ Proteolysisces an active signaling conformation. However, the details of this conformational change remain elusive until high-resolution crystal structures of different functional conformations are available. X-ray crystallography is a powerful tool to study structure–function relationships, but crystallizatio作者: lesion 時(shí)間: 2025-3-27 07:15 作者: enormous 時(shí)間: 2025-3-27 10:14
Structure Modeling of Toll-Like Receptorsissemination and for the development of acquired immunity. To understand how these receptors work, it is crucial to investigate them from a structural perspective. High-throughput genome sequencing projects have led to the identification of more than 3,000 TLR sequences. However, only several struct作者: 無畏 時(shí)間: 2025-3-27 14:06 作者: nautical 時(shí)間: 2025-3-27 20:58 作者: 鄙視讀作 時(shí)間: 2025-3-28 00:41
Analysis of Nucleic Acid-Induced Nonimmune Cell Death In Vitroattern recognition receptors by foreign nucleic acid promotes production of inflammatory cytokines (mostly type I IFNs) and at the later stage leads to cell death. Here, we describe reliable and simple methods to quantify cell death caused by nucleic acid recognition. Additionally, we report two dif作者: BRUNT 時(shí)間: 2025-3-28 04:40 作者: Munificent 時(shí)間: 2025-3-28 08:52 作者: 歌劇等 時(shí)間: 2025-3-28 14:17 作者: 總 時(shí)間: 2025-3-28 17:32
MicroRNA Methodology: Advances in miRNA Technologiesain microRNA specific methodologies and critical steps of microRNA expression profiling, target gene identification, and functional confirmation of microRNA effects up to in vivo application of antagomirs.作者: Self-Help-Group 時(shí)間: 2025-3-28 19:56
Expression Profiling by Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) amount of amplified specific sequence can be quantified at each stage of the PCR cycle. If investigated sequence is present in large number of copies in particular sample, amplification product is detected already in earlier cycles; if the sequence is rare, amplification is observed in later cycles作者: 執(zhí) 時(shí)間: 2025-3-29 00:56
Evaluating the Role of Nucleic Acid Antigens in Murine Models of Systemic Lupus Erythematosussus (SLE). Endogenous RNA- and DNA-containing autoantigens released from dying cells can engage Toll-like receptors (TLR) 7/8 and TLR9, respectively in a number of immune cell types, thereby promoting innate and adaptive immune responses. Mouse models of lupus reliably phenocopy many of the characte作者: delta-waves 時(shí)間: 2025-3-29 05:35 作者: CLAY 時(shí)間: 2025-3-29 08:17 作者: Adornment 時(shí)間: 2025-3-29 12:06
Bifunctional siRNAs for Tumor Therapyolecules can be generated synthetically by chemical synthesis or by in vitro transcription (. Chapter 2, Hornung et al.). Similar to viruses, they initiate an antiviral immune response, e.g., by stimulation of the immune system. Short, double-stranded RNA in the cytosol can also trigger the RNA inte作者: 概觀 時(shí)間: 2025-3-29 16:46 作者: apiary 時(shí)間: 2025-3-29 21:36
Fanny Matheis,Robert Besch Ph.D.s including finance, marketing, medicine, biology, engineering, telecommunications, software, and security..Data Mining and Knowledge Discovery Handbook, Second Edition. is designed for research scientists, lib978-0-387-09823-4作者: AUGUR 時(shí)間: 2025-3-30 00:02 作者: ALE 時(shí)間: 2025-3-30 06:20
ed spelling errors. When, subsequently, testing text is examined for context-based spelling errors, the logic formulas and a portion of the prior text are used to analyze the case at hand and to pinpoint likely errors. Tests conducted on different text samples indicate that the method is effective f作者: Psychogenic 時(shí)間: 2025-3-30 09:15 作者: Etching 時(shí)間: 2025-3-30 13:54 作者: sperse 時(shí)間: 2025-3-30 19:45
Moritz Rapp,David Anz,Max Schnurrh in-depth descriptions of data mining applications in various interdisciplinary industries including finance, marketing, medicine, biology, engineering, telecommunications, software, and security..Data Mining and Knowledge Discovery Handbook, Second Edition. is designed for research scientists, lib作者: 情節(jié)劇 時(shí)間: 2025-3-30 23:20 作者: Notify 時(shí)間: 2025-3-31 03:19 作者: 他很靈活 時(shí)間: 2025-3-31 06:16
A Modular Approach to Suppression Assays: TLR Ligands, Conditioned Medium, and Viral Infectionhe effect of any cell type, live and inactivated microorganisms, molecularly defined immunostimulatory ligands, and cytokines on the interplay of Teff and Treg function. Here, we demonstrate how the suppression assay can be used as a multifunctional tool to provide insights into the interaction of T作者: 有花 時(shí)間: 2025-3-31 11:44
Expression Profiling by Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR)s it is detectable. Correctly performed, this method may be used for precise gene expression analysis in life science, medicine, and diagnostics and has become the standard method of choice for the quantification of mRNA. However in the past few years it became obvious that real-time PCR is complex 作者: 引起痛苦 時(shí)間: 2025-3-31 14:09 作者: 不舒服 時(shí)間: 2025-3-31 19:00 作者: 碎石 時(shí)間: 2025-4-1 00:01
r, and the correctness of several properties that were assumed in the first part. Those who are interested only in using the analysis techniques themselves can skip the second part, but that part is important, if only to understand what is being done.978-1-4419-3767-4978-0-387-26351-9Series ISSN 0929-1296