標題: Titlebook: Immunotherapy and Biomarkers in Neurodegenerative Disorders; Martin Ingelsson,Lars Lannfelt Book 2016 Springer Science+Business Media New [打印本頁] 作者: Espionage 時間: 2025-3-21 18:32
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders影響因子(影響力)
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders影響因子(影響力)學科排名
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders網(wǎng)絡公開度
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders網(wǎng)絡公開度學科排名
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders被引頻次
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders被引頻次學科排名
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders年度引用
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders年度引用學科排名
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders讀者反饋
書目名稱Immunotherapy and Biomarkers in Neurodegenerative Disorders讀者反饋學科排名
作者: CBC471 時間: 2025-3-21 20:21 作者: Jargon 時間: 2025-3-22 03:33
Martin Ingelsson,Lars LannfeltIncludes cutting-edge techniques for the study of neurodegenerative disorders through immunotherapy and biomarker research.Offers state-of-the-art contributions from renowned experts.Features practica作者: Esophagus 時間: 2025-3-22 06:59 作者: 信任 時間: 2025-3-22 12:38
https://doi.org/10.1007/978-1-4939-3560-4Amyloid-Beta; Alzheimer’s Disease; Αlpha-Synuclein; Tau protein; Therapeutic antibodies; Monoclonal antib作者: A簡潔的 時間: 2025-3-22 16:15 作者: 腐爛 時間: 2025-3-22 18:38 作者: enumaerate 時間: 2025-3-22 23:26 作者: 彎曲道理 時間: 2025-3-23 01:28 作者: Cosmopolitan 時間: 2025-3-23 05:45
PET Imaging as a Diagnostic Tool in Alzheimer’s Diseasensmitter, and neuroinflammation ligands help to understand the pathophysiology of AD, but further studies are needed to understand how they can be applied in the diagnostic process. Which combination of these biomarkers that eventually will turn out to be the most sensitive and best predictor of AD remains to be determined.作者: 急急忙忙 時間: 2025-3-23 11:21 作者: Atmosphere 時間: 2025-3-23 16:10
1557-2153 he-art contributions from renowned experts.Features practica.This practical volume examines a number of topicsthat explore the current status of immunotherapy and diagnostic markers forneurodegenerative disorders. With a focus on Alzheimer’s disease, the firstsections of the book examine immunothera作者: aesthetician 時間: 2025-3-23 18:58 作者: Rct393 時間: 2025-3-24 01:47
Active Immunization Against the Amyloid-β Peptidegeting amyloid-β, specifically Aβ., as this protein is thought to initiate the cascade of events that lead to the disease. This chapter focuses on active immunotherapy (vaccines) and specifically on therapies that currently are in clinical development.作者: Obscure 時間: 2025-3-24 04:37 作者: Inexorable 時間: 2025-3-24 08:19
Alpha-Synuclein as a Diagnostic Biomarker for Parkinson’s Disease shown promising results, but further studies are needed to prove their diagnostic usefulness. In addition to analyses of body fluids, detection of α-synuclein in peripheral tissues—such as subcolonic mucosa and parotid gland—seem to offer novel interesting diagnostic possibilities.作者: 變白 時間: 2025-3-24 14:24 作者: ICLE 時間: 2025-3-24 16:45
Kiran Yanamandra,Marc I. Diamond,David M. Holtzman作者: 冷峻 時間: 2025-3-24 20:36
Joakim Bergstr?m,Martin Ingelsson M.D., Ph.D.ion frequently has not been confirmed by sensitive and specific laboratory tests. The goal of this chapter is to review and update earlier surveys (e.g., Strauss and Davis 1973; Jaffe 1978; Davis and Johnsson 1983; Schuknecht and Donovan 1986; Davis 1990, 1993) of the role of viruses in development 作者: 盲信者 時間: 2025-3-25 00:59 作者: 表示向下 時間: 2025-3-25 03:19
Sravani Musunuri,Ganna Shevchenko,Jonas Bergquist body constituents might be terminated by immunization with a cross-reactive antigen from the environment (266]. It cannot be overemphasized how difficult it could be, at least in several in- stances, to delineate specific from non-specific events in any immunological pro- cess. Cyclic AMP may be on作者: 責任 時間: 2025-3-25 08:30
Immunotherapy and Biomarkers in Neurodegenerative Disorders作者: FEAT 時間: 2025-3-25 15:24 作者: 強所 時間: 2025-3-25 19:35
Immunotherapy Against Amyloid-β in Alzheimer’s Disease: An Overviewspecifically aimed at protofibrils of Aβ species that are thought to be most toxic have been developed and are currently being tested in phase 1 and 2 clinical trials. The first active immunotherapy with AN1792 was halted because of severe side effects. New-generation active vaccination programs wit作者: 針葉類的樹 時間: 2025-3-25 22:25
Immunotherapy Against N-Truncated Amyloid-β Oligomersence of high Aβ levels in brain, are acting as a waste bin, thereby keeping toxic Aβ aggregates locally fixed in a nontoxic form. Another hypothesis claims that intraneuronal Aβ aggregation triggers neuron loss and lastly many researchers believe that soluble Aβ aggregates of full-length Aβ. are the作者: 一回合 時間: 2025-3-26 01:54 作者: Limousine 時間: 2025-3-26 06:59
Active and Passive Immunotherapy Against Tau: Effects and Potential Mechanismsying these effects is not clear. In this chapter, we review the recent active and passive immunization strategies targeting tau in mouse models and our understanding of potential mechanisms underlying the effects seen.作者: Mechanics 時間: 2025-3-26 12:11 作者: meditation 時間: 2025-3-26 15:22
Cerebrospinal Fluid Biomarkers in Alzheimer’s Diseaseand outcome measures for clinical trials. We describe both how such analyses are currently performed in clinical chemistry laboratories and the ongoing efforts to standardise analysis between different sites. Finally, we are also providing an overview of new markers in various stages of development 作者: 鑲嵌細工 時間: 2025-3-26 19:33
Imaging as a Diagnostic Tool in Parkinson’s Diseaseaphy (SPECT), can be used to detect dopamine deficiency, functional metabolic neuronal impairments and pathological accumulation of certain proteins in the nervous system. Similar to MRI, both PET and SPECT may also be used to aid in the differential diagnosis between Parkinson’s disease and other p作者: 案發(fā)地點 時間: 2025-3-26 23:30
Immunotherapy Against Amyloid-β in Alzheimer’s Disease: An Overviewents are urgently needed, and the amyloid cascade hypothesis thus far provides the best basis for the development of such therapies. Preclinical studies in mouse models of AD showed that immunization with amyloid-β (Aβ) as well as passive vaccination with monoclonal antibodies against Aβ may be effe作者: 故意釣到白楊 時間: 2025-3-27 01:31
Active Immunization Against the Amyloid-β Peptideeveral therapies have been approved to treat AD, all of which provide modest effect on the symptoms of the illness but without slowing or halting the underlying disease processes. Since the last of these therapies was approved, the largest research effort has been devoted to developing therapies tar作者: 激怒某人 時間: 2025-3-27 06:18
Immunotherapy Against N-Truncated Amyloid-β Oligomerser’s disease (AD), which is characterized by the presence of extracellular amyloid-Aβ plaques and intraneuronal neurofibrillary tangles consisting of tau protein. Numerous studies have demonstrated that the amyloid cascade triggers tau pathology, with tau being intimately involved in the molecular m作者: 南極 時間: 2025-3-27 11:07 作者: mitral-valve 時間: 2025-3-27 15:33
Immunotherapy Against α-Synuclein Pathologythat affects approximately 1.5 million people in the USA and 1 % of people over 60 years old. Both vaccination and passive immunization approaches with antibodies targeting alpha-synuclein (α-syn) have been extensively explored, especially since the discovery that this protein may propagate from cel作者: Musket 時間: 2025-3-27 21:23
Extracellular α-Synuclein as a Target for Immunotherapygrowing body of evidence suggests that α-synuclein, an intra-neuronal protein, is exocytosed from neurons and that extracellular α-synuclein could mediate the major pathological changes in PD, such as neurodegeneration, neuroinflammation, and progressive spreading of protein inclusions. Here, we rev作者: 空氣 時間: 2025-3-27 22:57 作者: 從屬 時間: 2025-3-28 02:53
Tau Immunotherapystudies by several groups have shown efficacy of various active and passive approaches in reducing pathological tau proteins. Clinical trials are clearly warranted and a few have already been initiated. However, much remains to be clarified regarding the mechanisms of action and how efficacy can be 作者: 水獺 時間: 2025-3-28 08:33 作者: 定點 時間: 2025-3-28 13:38 作者: 沙草紙 時間: 2025-3-28 15:07 作者: temperate 時間: 2025-3-28 22:15
Volumetric MRI as a Diagnostic Tool in Alzheimer’s Diseaseance imaging (MRI), have made it possible to study this pathological process in vivo. However, the use of clinical imaging in dementia evaluation is often suboptimal. Evidence supports the role of regional and global atrophy as well as white matter changes as markers of disease in dementia. There is作者: Endearing 時間: 2025-3-29 02:02
PET Imaging as a Diagnostic Tool in Alzheimer’s Diseasetively intact. It is yet unclear which additional factors that ultimately will determine progression to mild cognitive impairment and eventually to AD dementia. Amyloid-β (Aβ) and tau imaging reveal in vivo the key protein aggregates seen in the AD brain and will help in early diagnosis. However, a 作者: 可忽略 時間: 2025-3-29 04:12
Alpha-Synuclein as a Diagnostic Biomarker for Parkinson’s Diseasea. Although significant differences in the levels of total α-synuclein have been found between patients and controls, none of these markers have been proven clinically useful as there has been a substantial overlap between the groups. Instead, assessment of toxic prefibrillar α-synuclein species has作者: 要控制 時間: 2025-3-29 07:38 作者: Basilar-Artery 時間: 2025-3-29 13:28
Mass Spectrometry-Based Proteomics in Biomarker Discovery for Neurodegenerative Diseases), and amyotrophic lateral sclerosis (ALS) lead to disease-specific changes in the neuronal proteins. The usage of rapidly evolving proteomic technologies, such as mass spectrometry (MS), has opened new avenues to detect the changes in the protein expression in disease vs. control samples for unders作者: 坦白 時間: 2025-3-29 17:19
Joakim Bergstr?m,Martin Ingelsson M.D., Ph.D.ly all areas of clinical pathology, including disorders of the inner ear. As attention has focused increasingly on the role of viral infections in the pathogenesis of different diseases of the labyrinth, the body of clinical and experimental literature in this area has grown rapidly. In spite of the作者: Crumple 時間: 2025-3-29 20:35
Johan Wikstr?m M.D., Ph.D. 1,Torsten Danfors M.D., Ph.D.se have come about from the application of contemporary molecular biology, physiology, and imaging techniques that have been made available to all of biology in combination with discoveries in the domain of hearing. This volume, Clinical Aspects of Hearing, presents these pivotal developments as the作者: fabricate 時間: 2025-3-30 02:50 作者: Anticoagulants 時間: 2025-3-30 07:59 作者: 減去 時間: 2025-3-30 11:29
Training Competent Generalists,dditionally, we have analysed how having prior knowledge of 3D modelling software affects these processes. Our findings highlight distinctions in workflow efficiencies, user motivations and interaction paradigms, providing insights into the evolving landscape of digital content creation across various platforms.作者: 1FAWN 時間: 2025-3-30 13:24
The Delphi Method in Information Literacy Researchnly those of education, health care, and librarianship, leading to a variety of findings, most often relating to IL competence or skill framework. Delphi was used highly flexibly, utilizing diverse groups of experts with various signifiers of expertise. If applied rigorously, with other methods, Delphi may contribute to IL theory and practice.作者: 樂章 時間: 2025-3-30 16:37
What Happens to Communication?,ts to discuss various decision approaches and analytical models realized, evaluated and implemented by industries after careful assessment, based on the respective and customized network design models.作者: 彎彎曲曲 時間: 2025-3-31 00:41 作者: 中止 時間: 2025-3-31 02:30
Phytoremediation of Mine Waste Disposal Sites: Current State of Knowledge and Examples of Good Pracies is phytoremediation, with phytostabilization, phytovolatization, phytofiltration, and phytoextraction as main techniques. An overview of the past experiences is discussed together with future trends in phytoremediation.作者: Anthrp 時間: 2025-3-31 05:24 作者: 劇本 時間: 2025-3-31 10:38
Ashley L. C. Maganzo,Marlvern Mabgwef unmatched uncertainty?of the system is minimised. Furthermore, SMC?is calculated using the functional observer?method. Finally, a simulation example is given to show the effectiveness of the proposed method.作者: 道學氣 時間: 2025-3-31 16:24 作者: 野蠻 時間: 2025-3-31 20:05
Morally Upright Aryans and Immoral Jews, we examine the context of his remark, we can see that Hitler believed that the Jews were a threat to the very existence of humanity. Just prior to this famous quotation, Hitler explained how dangerous the Jews were:
