標(biāo)題: Titlebook: Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog; Bruce Beutler Book 2008 The Editor(s [打印本頁] 作者: 技巧 時(shí)間: 2025-3-21 18:49
書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog影響因子(影響力)
書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog影響因子(影響力)學(xué)科排名
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書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog網(wǎng)絡(luò)公開度學(xué)科排名
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書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog讀者反饋
書目名稱Immunology, Phenotype First: How Mutations Have Established New Principles and Pathways in Immunolog讀者反饋學(xué)科排名
作者: subordinate 時(shí)間: 2025-3-21 21:32 作者: 廣告 時(shí)間: 2025-3-22 01:05
Host Defenses Against Human Papillomaviruses: Lessons from Epidermodysplasia Verruciformis thus represent a primary deficiency in intrinsic, constitutive immunity to betapapillomaviruses, or constitute a primary deficiency in innate immunity (or both). Keratinocytes, the home cells of HPVs, are likely to play a central role in both cases. An important issue is to establish which cellular作者: EXUDE 時(shí)間: 2025-3-22 07:32
Innate Resistance to Flavivirus Infections and the Functions of 2′-5′ Oligoadenylate Synthetases some other diseases such as type 1 diabetes and multiple sclerosis. Finally, convergent observations indicate that the molecules encoded by the . cluster might be involved in other fundamental cellular functions such as cell growth and differentiation, gene regulation, and apoptosis.作者: monologue 時(shí)間: 2025-3-22 10:31
Genetic Dissection of Host Resistance to ,: The , Locus and the , Genemosome 1 and shown to be especially important for control of pulmonary tuberculosis. Rampant progression of tuberculosis infection in the lungs of the .-susceptible mouse was associated with the development of necrotic lung lesions, which was prevented by the .-resistant allele. Using a positional c作者: Lasting 時(shí)間: 2025-3-22 13:33
, the , Locus, and the Molecular Basis of Peripheral Tolerancemmune responses. Furthermore, although mutations in the orthologous human gene result in a virtually identical phenotype to that seen in the mouse, it is unlikely that studying the human disease populations alone would have successfully identified this gene. Thus, despite the complete sequencing of 作者: 奴才 時(shí)間: 2025-3-22 18:59
Fevers, Genes, and Innate Immunityme,” resulting in caspase-1 activation and subsequent release of the active proinflammatory cytokine interleukin-1β (IL-1β). The role of an established biochemical pathway in regulating inflammation was uncovered by the discovery that the hyperimmunoglobulin D with periodic fever syndrome (HIDS) res作者: Lament 時(shí)間: 2025-3-22 23:06 作者: Felicitous 時(shí)間: 2025-3-23 01:23 作者: 投射 時(shí)間: 2025-3-23 07:57 作者: 非秘密 時(shí)間: 2025-3-23 10:46
A. A. Scalzo,W. M. Yokoyamart of a wider social system.?This approach will be of interest to policy makers, educators, students and researchers in support of more pluralism in economic research and teaching..978-3-030-48425-5978-3-030-48423-1Series ISSN 2635-2621 Series E-ISSN 2635-263X 作者: Perennial長期的 時(shí)間: 2025-3-23 16:23 作者: 無政府主義者 時(shí)間: 2025-3-23 20:46 作者: 口味 時(shí)間: 2025-3-23 23:09 作者: 特征 時(shí)間: 2025-3-24 04:15 作者: Lucubrate 時(shí)間: 2025-3-24 07:47
I. Kramnikta, and Bagobo-Klata) in nature conservation. Another is?to create a local version of the Climate Change Commission’s database-sharing system. The system has to be continuously populated, open-access, interactive, and staffed by a technical unit with plantilla items. Disaster risk and climate inform作者: 歸功于 時(shí)間: 2025-3-24 14:37
M. W. Appleby,F. Ramsdellt address the major problem that plagues the country’s water resources sector: poor management. The sector is regulated by several legal frameworks, with each law separately prioritizing some aspect of the sector and assigning responsibilities to an assortment of departments and agencies at various 作者: Density 時(shí)間: 2025-3-24 15:53 作者: 手工藝品 時(shí)間: 2025-3-24 20:23
L. E. Matesic,N. G. Copeland,N. A. Jenkinsta, and Bagobo-Klata) in nature conservation. Another is?to create a local version of the Climate Change Commission’s database-sharing system. The system has to be continuously populated, open-access, interactive, and staffed by a technical unit with plantilla items. Disaster risk and climate inform作者: Prostaglandins 時(shí)間: 2025-3-25 00:38 作者: GEM 時(shí)間: 2025-3-25 04:18
aused by sensor drift occurring in the heating controls, positioning of humidity controls and reduced effectiveness of dehumidification systems in cold climates..Interventions are derived and modelled based on reducing undesirable air infiltration, segregation of conditioned and non-conditioned spac作者: ectropion 時(shí)間: 2025-3-25 08:42 作者: expound 時(shí)間: 2025-3-25 13:31 作者: CHOKE 時(shí)間: 2025-3-25 18:15
J. -F. Marquis,P. Gros0). It is therefore not surprising that endeavors to forecast them well in advance extend over a century, and that both the World Climate Program (World Meteorological Organization, 1980, p. 42) and the U.S. National Climate Program (National Climate Program Office, NOAA, 1980, pp. 23–24; 1988, pp. 作者: semiskilled 時(shí)間: 2025-3-25 23:56
G. Orths to be concentrated. The purpose of the present chapter is to review the large-scale environmental setting, and the regional and seasonal characteristics of prominent synoptic weather systems. Atmospheric disturbances are individuals rather than identical replicas of each other. Synoptic models are作者: 追逐 時(shí)間: 2025-3-26 00:27
T. Mashimo,D. Simon-Chazottes,J. -L. Guénethin science has relevance for society and nature..Provides jThis book is a philosophical critique of the economics of climate change from both an ethical and philosophy of economics perspective.?Mitigating climate change is not so much a scientific problem, but rather a political, social and above a作者: stratum-corneum 時(shí)間: 2025-3-26 08:18
A. A. Scalzo,W. M. Yokoyamahin science has relevance for society and nature..Provides jThis book is a philosophical critique of the economics of climate change from both an ethical and philosophy of economics perspective.?Mitigating climate change is not so much a scientific problem, but rather a political, social and above a作者: occult 時(shí)間: 2025-3-26 09:02
I. Kramnik, properties, public and private investments in development, and the physical and mental health of surviving families in affected .. The past decade experienced an average of two floods/year.?Twenty-one of the 36 vulnerable?barangays in the Basin are prone to 100-year return?flooding. Four (. 8-A, M作者: Legion 時(shí)間: 2025-3-26 15:31 作者: expound 時(shí)間: 2025-3-26 18:49
J. G. Ryan,D. L. Kastnerating the accelerated impacts of climate change in the Philippines. The increased frequency and severity of climate impacts increases the burden of financing to address wide ranging loss and damage the country suffers. This chapter asks whether the Philippines’ climate and disaster financing policie作者: 莎草 時(shí)間: 2025-3-27 00:22 作者: flammable 時(shí)間: 2025-3-27 04:09
D. T. Umetsu,S. E. Umetsu,G. J. Freeman,R. H. DeKruyffPM is truly a life skill, then it is important to start learning it at an early age, but can it be taught to children and if so, how? If PM can be taught, is it possible to integrate STEM, construction industry practice and sustainability themes? This is an important question for developing a genera作者: ANTIC 時(shí)間: 2025-3-27 07:32
t corrosion and damage to the electrical distribution equipment housed within substations; a minimum temperature is required to enable dehumidification systems to operate effectively..Remote monitoring and site investigations are utilised to investigate the effectiveness of installed environmental c作者: 合唱團(tuán) 時(shí)間: 2025-3-27 10:05
The Forward Genetic Dissection of Afferent Innate Immunity the innate immune response. Known as the Toll-like receptors (TLRs), these molecules are represented among most metazoans. In mammals, forward genetic analysis of the lipopolysaccharide (LPS) response led to the identification of TLR4 as the LPS receptor. Through a combination of forward and revers作者: Juvenile 時(shí)間: 2025-3-27 14:15
Genetic Analysis of Resistance to Infections in Mice: A/J meets C57BL/6Jifficult to study as it is further modified by environmental factors including the disease-causing pathogen itself. The laboratory mouse has proved a useful alternative to implement a genetic approach to study host defenses against infections. Our laboratory has used genetic analysis and positional 作者: 蘑菇 時(shí)間: 2025-3-27 20:33
Host Defenses Against Human Papillomaviruses: Lessons from Epidermodysplasia Verruciformisharacterized by the abnormal susceptibility of otherwise healthy patients to infection by specific, weakly virulent human papillomaviruses (HPVs), including the potentially oncogenic HPV-5. Inactivating mutations in either of the related . and . genes cause most EV cases. New insights in EV pathogen作者: Gerontology 時(shí)間: 2025-3-27 23:54 作者: Pessary 時(shí)間: 2025-3-28 02:59 作者: 推崇 時(shí)間: 2025-3-28 07:20 作者: jungle 時(shí)間: 2025-3-28 10:55
, the , Locus, and the Molecular Basis of Peripheral Tolerance. When it fails, however, autoimmune disease results. The genetic and environmental factors that control the process of making such distinctions, not to mention the specific targeted tissues, are extraordinarily complex in the human population; only now are we characterizing the candidate genes resp作者: 小口啜飲 時(shí)間: 2025-3-28 17:16
Fevers, Genes, and Innate Immunityce of these conditions and facilitated the subsequent identification of causative gene mutations. The prototype autoinflammatory syndrome, familial Mediterranean fever, is characterized by self-limiting episodes of localized inflammation. Hallmarks of the classical autoimmune response are largely ab作者: 截?cái)?nbsp; 時(shí)間: 2025-3-28 22:21
Mice: The Identification of a New Pathway for the Development of Autoimmunityve autoimmune disease that proves lethal beginning at 6 months of age. Numerous targets of Itch-mediated ubiquitination have been identified, and some of these have defined physiological roles for Itch signaling in T cell anergy and T cell differentiation. Studies of . mice have also allowed for the作者: Flinch 時(shí)間: 2025-3-28 23:19 作者: generic 時(shí)間: 2025-3-29 05:10 作者: 紀(jì)念 時(shí)間: 2025-3-29 10:12
