標(biāo)題: Titlebook: Immuno-Oncology; Cellular and Transla Seng-Lai Tan Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Cancer immu [打印本頁(yè)] 作者: trace-mineral 時(shí)間: 2025-3-21 17:35
書(shū)目名稱Immuno-Oncology影響因子(影響力)
作者: magnate 時(shí)間: 2025-3-21 23:17 作者: GORGE 時(shí)間: 2025-3-22 01:24
978-1-0716-0173-0Springer Science+Business Media, LLC, part of Springer Nature 2020作者: LAST 時(shí)間: 2025-3-22 05:43 作者: 扔掉掐死你 時(shí)間: 2025-3-22 09:56 作者: unstable-angina 時(shí)間: 2025-3-22 15:25 作者: 精致 時(shí)間: 2025-3-22 19:00
Correction to: Considerations in Developing Reporter Gene Bioassays for Biologics,作者: 無(wú)法破譯 時(shí)間: 2025-3-22 21:51 作者: excursion 時(shí)間: 2025-3-23 04:35 作者: COM 時(shí)間: 2025-3-23 08:19 作者: 窩轉(zhuǎn)脊椎動(dòng)物 時(shí)間: 2025-3-23 09:52 作者: 打折 時(shí)間: 2025-3-23 15:31
Leanne Flye-Blakemore,Christèle Gonneau,Nithianandan Selliah,Ajay Grover,Sriram Ramanan,Alan Lackey, population..We conclude with a consideration of the role of models relating allele and genotype frequencies in populations of cyclical parthenogens. Because the breeding system of these populations infrequently involves recombination between clones, models such as the Hardy-Weinberg have limited va作者: Crohns-disease 時(shí)間: 2025-3-23 19:05
Jinze Li,Mayur S. Mitra,Gautham K. Raout was observed. Broad-sense heritabilities were found to be relatively high for some life history traits (size at maturity, neonate size, number of neonates) as well as for the phenotypic plasticity response of these traits. This reflects the evolutionary potential of life history traits and their 作者: AV-node 時(shí)間: 2025-3-23 22:51
Leonardo Mirandola,Franco Marincola,Gianluca Rotino,Jose A. Figueroa,Fabio Grizzi,Robert Bresalier,Mideological work stems from the fact that in capitalism the logic of efficiency is hegemonic, and this is not easily conducive to the justification of status differentials. This is why managerial discourses are never open, straightforward, and why they are, in sum, clearly ideological.978-1-4613-7301-8978-1-4615-5061-7作者: 反復(fù)無(wú)常 時(shí)間: 2025-3-24 05:47
Jamison Grailer,Richard A. Moravec,Zhijie Jey Cheng,Manuela Grassi,Vanessa Ott,Frank Fan,Mei Congl work stems from the fact that in capitalism the logic of efficiency is hegemonic, and this is not easily conducive to the justification of status differentials. This is why managerial discourses are never open, straightforward, and why they are, in sum, clearly ideological.作者: Infelicity 時(shí)間: 2025-3-24 08:22
Tomasz Dobrzycki,Andreea Ciuntu,Andrea Stacey,Joseph D. Dukes,Andrew D. Whale作者: Expand 時(shí)間: 2025-3-24 12:23 作者: Exploit 時(shí)間: 2025-3-24 15:57
Lynne S. Dunsford,Rosie H. Thoirs,Emma Rathbone,Agapitos Patakas作者: OPINE 時(shí)間: 2025-3-24 22:25 作者: 農(nóng)學(xué) 時(shí)間: 2025-3-25 01:08
fluential nature, and also explains how populists construct civilizational identities, and the?factors behind the rise of civilizational populism..978-981-99-4264-0978-981-99-4262-6Series ISSN 2731-3069 Series E-ISSN 2731-3077 作者: 本土 時(shí)間: 2025-3-25 03:32 作者: 壓倒 時(shí)間: 2025-3-25 11:03
In Vitro Functional Assay Using Real-Time Cell Analysis for Assessing Cancer Immunotherapeutic Agenl-time manner. This specialized microtiter plate system uses integrated gold microelectrodes as a sensor to measure the electronic current flow that is impeded by the tumor cells attached on the sensor surface. This measured impedance signal is dictated by cell number, size, and surface attachment s作者: Antagonist 時(shí)間: 2025-3-25 11:49 作者: malign 時(shí)間: 2025-3-25 18:26
Induction and Potential Reversal of a T Cell Exhaustion-Like State: In Vitro Potency Assay for Function to persistent antigen exposure, TILs within the TME encounter numerous tumor-mediated immunosuppressive metabolic by-products, suppressive cytokines, hypoxia, and cellular debris which converge to suppress T cell function and uniquely alter its transcription factor profile. These suppressed or 作者: Commodious 時(shí)間: 2025-3-25 21:00 作者: 能量守恒 時(shí)間: 2025-3-26 03:35
Miniaturized Single Cell Imaging for Developing Immuno-Oncology Combinational Therapies,nt, enabling screening of up to 50 drug conditions per one million primary cells. This approach also employs the capability to perform digitized molecular counting to quantify surface and intracellular . This miniaturized single cell imaging approach offers new capabilities for assessing the functio作者: 懶惰人民 時(shí)間: 2025-3-26 06:20 作者: Compassionate 時(shí)間: 2025-3-26 10:14
The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Erhe general low affinity of T-cell receptors (TCRs) for self-antigens..Recent efforts have, therefore, been directed towards the discovery and validation of neoantigens, that arise from mutations in cancer cells. Emerging alternatives to neoantigens are mutational hotspot antigens and cancer-specific作者: Definitive 時(shí)間: 2025-3-26 16:31 作者: Junction 時(shí)間: 2025-3-26 20:07
Min Dai,Ingegerd Hellstrom,Karl Erik Hellstromship between civilizational populism, democracy and national.This edited book examines the growing worldwide phenomenon of civilizational populism in democratic nation-states and brings together research that explores this in a wide variety of religious, political, and geographic contexts. In doing 作者: Anticoagulant 時(shí)間: 2025-3-26 21:42 作者: 卷發(fā) 時(shí)間: 2025-3-27 04:06 作者: 有幫助 時(shí)間: 2025-3-27 06:34
Thomas Jacob,Pavani Malla,Tania Vuhat the chydorid Cladocera are not cosmopolitan in distribution but instead are restricted to smaller regions by their specific ecological requirements for habitat type and also by long-term events in earth history. Recent study of . and species resembling it indicates there has been no effective ex作者: 收藏品 時(shí)間: 2025-3-27 12:03 作者: 注視 時(shí)間: 2025-3-27 14:14 作者: 實(shí)施生效 時(shí)間: 2025-3-27 17:54
Leonardo Mirandola,Franco Marincola,Gianluca Rotino,Jose A. Figueroa,Fabio Grizzi,Robert Bresalier,Mates, is the attention that European scholars give to the managerial discourse and rhetorics, especially in their textual or written embodiments. In fact, it is one of the few topics where the usual dominance of American scholarship (Engwall, 1998) does not hold. Discourses in management address bas作者: 四指套 時(shí)間: 2025-3-27 22:08
Jamison Grailer,Richard A. Moravec,Zhijie Jey Cheng,Manuela Grassi,Vanessa Ott,Frank Fan,Mei Conghe attention that European scholars give to the managerial discourse and rhetorics, especially in their textual or written embodiments. In fact, it is one of the few topics where the usual dominance of American scholarship (Engwall, 1998) does not hold. Discourses in management address basically two作者: Trypsin 時(shí)間: 2025-3-28 06:00 作者: osteopath 時(shí)間: 2025-3-28 07:43
In Vitro Functional Assay Using Real-Time Cell Analysis for Assessing Cancer Immunotherapeutic Agenchimeric antigen receptor (CAR)-based T cell therapy and monoclonal antibodies targeting immune checkpoints, namely, CTLA4, PD-1, and PD-L1. However, while the advancement of the cancer immunotherapy has brought tremendous hope to some patients, there is a pressing need for more predictive in vitro 作者: Jingoism 時(shí)間: 2025-3-28 13:41 作者: 公理 時(shí)間: 2025-3-28 15:40 作者: 別炫耀 時(shí)間: 2025-3-28 20:19 作者: 虛假 時(shí)間: 2025-3-28 23:04
Validation of an Image-Based 3D Natural Killer Cell-Mediated Cytotoxicity Assay,chnology induced HCT116 cells to aggregate into tumoroids over time, which became the target cells during the cytotoxicity assay. Cytotoxicity was assessed by both phosphatidyl serine exposure (apoptosis) and plasma membrane rupture (necrosis) using fully automated workflows. Cytotoxicity was quanti作者: 礦石 時(shí)間: 2025-3-29 03:57 作者: 一起平行 時(shí)間: 2025-3-29 10:30
Considerations in Developing Reporter Gene Bioassays for Biologics,ial in biologic drug development. Here we describe a simple bioluminescent reporter gene bioassay for assessing biologics targeting immune checkpoints without the complexity and variability of more traditional assay systems. This chapter provides an overview of key considerations in reporter gene bi作者: 使長(zhǎng)胖 時(shí)間: 2025-3-29 12:56
Miniaturized Single Cell Imaging for Developing Immuno-Oncology Combinational Therapies,onventional chemotherapies and to single agents, remains a major hurdle. A current approach to combating drug resistance and risk of cancer recurrence is to find combinations of drugs that effectively target multiple functional pathways, increasing the prospect of providing more durable cancer cell 作者: 懸崖 時(shí)間: 2025-3-29 19:20
Precision Medicine: The Function of Receptor Occupancy in Drug Development,le to simultaneously measure over 50 parameters at the single-cell level and within complex mixtures of cells with significant precision. Along with immunophenotyping and functional testing used for clinical immune monitoring, receptor occupancy (RO) assays have become a standard application in flow作者: 使饑餓 時(shí)間: 2025-3-29 21:49
In Vitro Assays for Assessing Potential Adverse Effects of Cancer Immunotherapeutics,to activate the immune system and elicit anticancer immune responses, a majority of adverse effects noted with CIT drugs are related to the molecule’s pharmacology and exaggeration of pharmacological responses. A major challenge for CIT is that nonclinical toxicity studies utilizing healthy animals 作者: conceal 時(shí)間: 2025-3-30 02:44
The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Ermajority of cancer patients, especially those with solid tumors. Chimeric antigen receptor (CAR) T-cell therapies, for example, are far from being successfully implemented..A bottleneck in modern immunotherapy of cancer is the identification of molecules that allow effective targeting of the tumor w作者: Aerate 時(shí)間: 2025-3-30 05:10
1557-2153 developing next generation translational assaysThis book serves as a guide for identifying and applying commonly used cell-based translational assays as well as for assessing the therapeutic potential of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters作者: 周興旺 時(shí)間: 2025-3-30 11:42
Book 2020ial of new immuno-oncology therapeutics and advancing their mechanism of action. The detailed chapters within will provide readers with a baseline understanding of the pros and cons as well as key considerations for applying assays that are more reflective of the human immune-tumor microenvironment 作者: 放逐 時(shí)間: 2025-3-30 13:16
High-Throughput Direct Cell Counting Method for Immuno-Oncology Functional Assays Using Image Cytomages. In this chapter, we describe the?use of Celigo Image Cytometer for immuno-oncology functional assays such as complement-dependent cytotoxicity?(CDC), antibody-dependent cell-mediated cytotoxicity?(ADCC), T cell proliferation, and T cell migration.作者: 使迷醉 時(shí)間: 2025-3-30 17:11 作者: agitate 時(shí)間: 2025-3-30 21:01
Considerations in Developing Reporter Gene Bioassays for Biologics, without the complexity and variability of more traditional assay systems. This chapter provides an overview of key considerations in reporter gene bioassay design and optimization, as well as development of thaw-and-use cells as an assay reagent for biologic QC lot release.作者: preeclampsia 時(shí)間: 2025-3-31 03:29 作者: 擁擠前 時(shí)間: 2025-3-31 08:54 作者: 槍支 時(shí)間: 2025-3-31 11:13
Book 2008 discussed below. Nevertheless, the “Preface” would be grossly incomplete without touching on some of these issues, books, and scholars. Too, many of this book’s chapters (e. g. , Mora’s, Marx’s, D. B. Weiner’s) examine and “reference” important earlier, as well as contemporary, general histories of
