標題: Titlebook: IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2; William Paton,James Mitchell,Paul Turner Conference proceedings 198 [打印本頁] 作者: Jejunum 時間: 2025-3-21 16:36
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2影響因子(影響力)
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2影響因子(影響力)學(xué)科排名
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2網(wǎng)絡(luò)公開度
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2被引頻次
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2被引頻次學(xué)科排名
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2年度引用
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2年度引用學(xué)科排名
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2讀者反饋
書目名稱IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2讀者反饋學(xué)科排名
作者: 監(jiān)禁 時間: 2025-3-22 00:17
The active site of phospholipase A2also on the mobility of parts of the polypeptide chain which do not immediately belong to the active site. This became apparent from a comparison of the structure of native pancreatic phospholipase A. and its precursor. This mobility is closely linked to the condition of the N-terminus.作者: 飛行員 時間: 2025-3-22 02:07
N.m.r. studies of drug-receptor interactions as an aid to drug designl properties on the one hand and biological activity on the other, have made major contributions to the design of new and effective drugs, although for most systems the receptor remained simply an idea.作者: 鉗子 時間: 2025-3-22 07:59
Physicochemical properties in structure-activity analysis of parameters representing changes in hydrophobic, electronic, and steric effects within the series. This enables conclusions to be drawn regarding the influence of physicochemical properties on drug transport or on drug binding.作者: 浪蕩子 時間: 2025-3-22 11:45
From foxglove to the heart: classification and mode of action of inotropic agentsf different alterations. Then, I will briefly review the most important classes of drugs (β agonists and cardiac glycosides), and discuss the properties of endogenous factors that could play a role in physiological and pathological situations.作者: 戲法 時間: 2025-3-22 16:18 作者: CONE 時間: 2025-3-22 19:50
Lipomodulin, a naturally occurring phospholipase A2 inhibitory proteiniological and physiological functions. Since arachidonic acid is released from the cells responding to physiological and pathological stimuli (Kuehl & Egan, 1980), specific inhibitors for phospholipase A. will provide insights to exploit more detailed roles of phospholipase A. in many intracellular events.作者: 樂章 時間: 2025-3-23 00:08 作者: 咽下 時間: 2025-3-23 04:45
The role of adrenaline in essential hypertension in manve feedback loop through the putative pre-synaptic β-adrenoceptor, and hence causes a sustained increase in noradrenaline release (Adler-Graschinsky & Langer, 1975; Stjarne & Brundin, 1975; Dahlof, 1981).作者: N防腐劑 時間: 2025-3-23 05:42 作者: circuit 時間: 2025-3-23 09:51 作者: 歌唱隊 時間: 2025-3-23 16:19
Glucocorticoid-induced phospholipase inhibitory proteinsids are generally considered as ‘pharmacological actions’ since they are observed when amounts of steroids experimentally used in . or . studies are present in concentrations greater than those found under natural or physiological conditions.作者: 信任 時間: 2025-3-23 19:28
Receptor mapping by means of interaction energy calculationsic and electronic adaptability of the single members of the series to the receptor. This adaptability can be tested by determination of energies of interaction between drugs and their corresponding receptor binding sites. Hence a correlation between biological activities and binding strengths should be found within an antagonistic drug series.作者: bizarre 時間: 2025-3-23 22:22 作者: Accord 時間: 2025-3-24 03:24 作者: nepotism 時間: 2025-3-24 09:54
Macmillan Publishers Limited 1984作者: Irksome 時間: 2025-3-24 13:29 作者: Preamble 時間: 2025-3-24 15:45 作者: insomnia 時間: 2025-3-24 19:14 作者: Hypomania 時間: 2025-3-25 02:42
Phospholipase A2 inhibitors Introduction: an overview acid and a lysophosphoglyceride, is widely distributed in almost all animal tissues. In mammalian cells, the phospholipids are a major source of arachidonic acid for biosynthesis of prostanoids (prostaglandins, thromboxanes, and leukotrienes). Since prostanoids are not stored within cells, biosynth作者: 槍支 時間: 2025-3-25 05:19
The active site of phospholipase A2the active site. If one for example reacts the essential His 48 in phospholipase A. with an acylating reagent such as .-bromophenacyl-bromide all activity is lost. However the activity of phospholipase A. towards phospholipid micelles depends not only on the integrity of the active site itself, but 作者: 羊齒 時間: 2025-3-25 08:05
Lipomodulin, a naturally occurring phospholipase A2 inhibitory proteinyunsaturated fatty acid, and is often found to be arachidonic acid, a precursor of prostaglandins and leukotrienes (Van Den Bosh, 1980). The latter compounds are well known to have diverse biological actions such as inflammation, pain, fever and so on (Kuehl & Egan, 1980). Lysophosphatidylcholine, t作者: 他去就結(jié)束 時間: 2025-3-25 13:36
Renocortin: a phospholipase A2 inhibitory protein induced by anti-inflammatory steroids: pharmacology, ribonucleic acid (RNA) and new protein synthesis (Russo-Marie ., 1979). As it had been previously demonstrated that steroids were inhibiting PG synthesis by inhibiting the release of arachidonic acid from their membrane phospholipid stores, probably by inhibiting the enzyme responsible for the ph作者: kidney 時間: 2025-3-25 16:01
Glucocorticoid-induced phospholipase inhibitory proteinsall the clinical signs and symptoms of acute and chronic inflammation, that is pain, redness, heat and swelling. Such profound effects of glucocorticoids are generally considered as ‘pharmacological actions’ since they are observed when amounts of steroids experimentally used in . or . studies are p作者: 游行 時間: 2025-3-25 23:59
The role of adrenaline in essential hypertension in manam, the plasma concentration must be increased several-fold — well above the range encountered during most daily activities — before any change in blood pressure is observed; and the change, when it occurs, is a fall in diastolic blood pressure together with increased systolic blood pressure (Clutte作者: 機械 時間: 2025-3-26 01:49
Glutathione and tissue toxicityde in a number of important cell functions. Thus, known physiological functions of glutathione now include maintenance of membrane integrity and cytoskeletal organization, involvement in protein and DNA synthesis, modification of protein conformation and enzyme activity, and promotion of neurotransm作者: irreducible 時間: 2025-3-26 05:36
Symposium 13: Analysis of drug mechanisms by single ion channel recording — An Overviewe ion channels, each of which carries a current of the order of a picoampere. With a standard two-electrode voltage clamp the peak-to-peak baseline noise is at least 250 pA, so it was obviously impossible to resolve the currents through individual ion channels. The discovery by Neher & Sakmann of a 作者: antiquated 時間: 2025-3-26 10:50 作者: 格子架 時間: 2025-3-26 13:43 作者: Fsh238 時間: 2025-3-26 17:23 作者: Overthrow 時間: 2025-3-26 22:12
esents contributions from the 2016 ALECTOR International Con.This proceedings volume explores the socio-economic dimension of the heritage sector from a broad, interdisciplinary perspective. Featuring contributions from the 2016 ALECTOR International Conference held in Istanbul, Turkey, this book pr作者: jaunty 時間: 2025-3-27 01:34
loped to communicate local heritage to international audiences. A cross-border partnership, operating in seven countries (Greece, Romania, Bulgaria, Ukraine, Georgia and Turkey), has developed standards for heritage tourism by involving key stakeholders, local communities and citizens into heritage 作者: 注意 時間: 2025-3-27 08:27 作者: 諂媚于人 時間: 2025-3-27 12:46 作者: QUAIL 時間: 2025-3-27 16:05 作者: aqueduct 時間: 2025-3-27 21:43 作者: DEVIL 時間: 2025-3-27 23:17
H.-D. H?ltje,M. Tintelnot,P. Baranowskility treatment approach in conjunction with chemotherapy and surgery in an attempt to control the disease locally. The complex anatomy of the pleura and its proximity to vital organs at risk, such as the lungs, heart, esophagus, and brachial plexus, pose distinct challenges. Novel techniques such as作者: vitrectomy 時間: 2025-3-28 02:57 作者: glomeruli 時間: 2025-3-28 09:05 作者: G-spot 時間: 2025-3-28 12:57
tive-emotional and multi-sensory experiences can foster an (inter)-active knowledge acquisition pattern for non-captive audiences at heritage places; (b) how to integrate new technologies into the cultural heritage experience to support the informal learning modus; and (c) how to democratize the mis作者: 胰臟 時間: 2025-3-28 16:21 作者: Detain 時間: 2025-3-28 21:28
R. Renetseder,B. W. Dijkstra,K. H. Kalk,J. Drenthontrast, seeks to deal with mental health as a theme in its own right alongside that of mental health care. This task led to the establishment of a broadly based committee whose members possessed a wide range of knowledge and experience in the field. The study was carried out by an equally expert team from th978-0-7923-1565-0978-94-011-2638-0作者: 絕食 時間: 2025-3-29 00:44 作者: AUGUR 時間: 2025-3-29 05:15
H.-D. H?ltje,M. Tintelnot,P. Baranowskirming high-quality multicenter prospective clinical trials that may determine the true efficacy of the addition of RT to surgical and systemic therapies. RT also plays an important role in the palliation of MPM-related pain, obstructive symptoms, and vascular invasion.作者: outskirts 時間: 2025-3-29 09:13
G. C. K. Robertsurectomy and decortication or extrapleural pneumonectomy with neoadjuvant or adjuvant therapy. Considering the overall survival and quality of life, pleurectomy and decortication is at present the preferred approach for MCR in majority of patients with MPM.作者: 吼叫 時間: 2025-3-29 12:59 作者: 精確 時間: 2025-3-29 15:43
IUPHAR 9th International Congress of Pharmacology: Proceedings, vol 2作者: Mast-Cell 時間: 2025-3-29 20:45 作者: Neuralgia 時間: 2025-3-29 23:52
The use of isolated mammalian cardiac myocytes for the study of inotropic mechanismstrical activity associated with contraction in individual cardiac myocytes. We have chosen to compare the actions of inotropic agents on myocytes from rats and guinea pigs since it appears that there are some differences in excitation-contraction coupling in these two species, and these differences 作者: deriver 時間: 2025-3-30 07:12 作者: 確定 時間: 2025-3-30 11:06
D. Colquhounh to have a consulting psychiatrist on-site, available to answer any questions that come up and see patients directly when they need an expert opinion. This is exactly what David S Kroll, MD, an Associate Vice 978-3-031-08494-2978-3-031-08495-9作者: 刻苦讀書 時間: 2025-3-30 15:38
M J. Brown,R. C. Causon,V. Barnes,P. Brennan,G. Barnes,G. Greenberg,W. E. Miall作者: judicial 時間: 2025-3-30 19:56 作者: headway 時間: 2025-3-30 23:21 作者: hedonic 時間: 2025-3-31 01:53
Decentralizing Inner-Product Functional Encryptionons of DMCFE schemes in the standard model (from DDH, Paillier, or LWE) but without labels. From Chotard et al., we obtain a DMCFE scheme with labels still in the random oracle model, but without pairings.作者: 裁決 時間: 2025-3-31 05:36
K-Nearest Neighborst part to play in this book. The chapter starts with an introduction to foundations in machine learning and decision theory with a focus on classification and regression. For the model selection problem, basic methods like cross-validation are introduced. Nearest neighbor methods are based on the la作者: 態(tài)學(xué) 時間: 2025-3-31 09:41
R. Grahame periodontium (i.e., the alveolar bone, the periodontal ligament, and the cementum). The reestablishment of its original structure, properties, and function constitutes a significant challenge in the development of new therapies to regenerate tooth-supporting defects. Preclinical models represent a作者: configuration 時間: 2025-3-31 13:55
trend. The load of the global Internet backbone will soon increase to tens of terabits per second. This indicates that the backbone bandwidth requirements will increase by a factor of 50 to 100 every seven years. Transportation of such high volumes of data requires suitable media with low loss and h
