標(biāo)題: Titlebook: Hypoxia and Cancer; Biological Implicati Giovanni Melillo Book 2014 Springer Science+Business Media New York 2014 cancer.microenvironment.t [打印本頁] 作者: 公款 時間: 2025-3-21 18:57
書目名稱Hypoxia and Cancer影響因子(影響力)
書目名稱Hypoxia and Cancer影響因子(影響力)學(xué)科排名
書目名稱Hypoxia and Cancer網(wǎng)絡(luò)公開度
書目名稱Hypoxia and Cancer網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Hypoxia and Cancer被引頻次
書目名稱Hypoxia and Cancer被引頻次學(xué)科排名
書目名稱Hypoxia and Cancer年度引用
書目名稱Hypoxia and Cancer年度引用學(xué)科排名
書目名稱Hypoxia and Cancer讀者反饋
書目名稱Hypoxia and Cancer讀者反饋學(xué)科排名
作者: flaunt 時間: 2025-3-21 20:45 作者: 察覺 時間: 2025-3-22 01:00 作者: 禁令 時間: 2025-3-22 05:39
Hypoxia and Reactive Oxygen Speciesrobic metabolism but also as important signaling molecules in various physiological and pathophysiological conditions. This has broadened the field of oxygen signaling in a substantial way given the fact that superoxide is derived from molecular oxygen. In this regard ROS and ROS-dependent signaling作者: Insubordinate 時間: 2025-3-22 09:56 作者: Microgram 時間: 2025-3-22 16:13
Carbonic Anhydrase IX: From Biology to Therapy of adaptive transcriptional changes mediated primarily by the hypoxia-inducible factor (HIF), and via stimulation of ion transport machinery maintaining normal intracellular pH. In addition, through these adaptive responses tumor cells acquire new features endowing them with selective advantage in 作者: 要素 時間: 2025-3-22 17:11 作者: jaunty 時間: 2025-3-23 00:52
Clinical Imaging of Hypoxiao be a source of resistance to conventional therapy, especially radiation and certain types of chemotherapy. Such hypoxic cells also play an important role in influencing malignant progression in terms of both enhancing growth of the primary tumour and increasing metastatic spread. Numerous attempts作者: meretricious 時間: 2025-3-23 05:06 作者: 拖網(wǎng) 時間: 2025-3-23 05:32
The Unfolded Protein Response and Therapeutic Opportunitiesent, including hypoxia. Although the most studied cellular signaling pathway induced by hypoxia is mediated by the transcriptional activity of hypoxia-inducible factors (HIFs), several HIF-independent mechanisms have been implicated in hypoxic adaptation, especially in the regulation of macromolecul作者: Simulate 時間: 2025-3-23 12:02 作者: 無動于衷 時間: 2025-3-23 17:41
Hypoxia and Radiation Therapye of different approaches that can reduce or eliminate tumor hypoxia and improve radiation response. Several of these have been tested clinically and in particular in combination with radiotherapy targeting hypoxia has proven beneficial. In order to target hypoxia specifically, a range of clinically作者: MERIT 時間: 2025-3-23 20:49
Prodrug Strategies for Targeting Tumour Hypoxiaentral roles in tumour progression and resistance to cytotoxic chemotherapy and radiotherapy. While many molecular targets may offer synthetic lethal interactions with hypoxia, the development of prodrugs that are activated to generate cytotoxins by one-electron (1e) reduction in hypoxic cells repre作者: 喧鬧 時間: 2025-3-23 23:41 作者: gonioscopy 時間: 2025-3-24 05:21 作者: 皮薩 時間: 2025-3-24 06:41 作者: 正論 時間: 2025-3-24 14:04
https://doi.org/10.1007/978-3-0348-6639-2of the tumor. Severe levels of hypoxia (
作者: 有限 時間: 2025-3-24 17:28
Wie Unternehmen sich selbst erneuernork has provided support to the idea that noncoding RNAs (ncRNAs), and in particular microRNAs (miRNAs), may play important roles in the adaptive response to low oxygen in tumors. Specifically, all published studies agree that the induction of microRNA-210 (miR-210) is a consistent feature of the hy作者: 欲望 時間: 2025-3-24 19:56 作者: Demulcent 時間: 2025-3-25 01:09 作者: BURSA 時間: 2025-3-25 07:03
Wie allein sind Alleinerziehende? of adaptive transcriptional changes mediated primarily by the hypoxia-inducible factor (HIF), and via stimulation of ion transport machinery maintaining normal intracellular pH. In addition, through these adaptive responses tumor cells acquire new features endowing them with selective advantage in 作者: 粗魯性質(zhì) 時間: 2025-3-25 09:22 作者: 使長胖 時間: 2025-3-25 13:59 作者: GEAR 時間: 2025-3-25 16:53
,Rückblick auf die Zielsetzung,deed the presence of hypoxia in the primary tumor has been identified as a prognostic indicator of treatment outcome in a number of clinical settings. Hypoxic conditions can arise at the limits of oxygen diffusion from blood vessels (diffusion or chronic hypoxia) or as a consequence of vascular coll作者: Cumulus 時間: 2025-3-25 23:10 作者: ovation 時間: 2025-3-26 01:51
Wie aus Ideen Pr?sentationen werdens both a major challenge and a substantial opportunity in the treatment of cancer. These adaptations influence a wide range of cellular processes, including cell cycle, metabolism, oxygen delivery, proliferation, energy production, differentiation, replication, and sensitivity to growth and death si作者: Peristalsis 時間: 2025-3-26 05:26 作者: 藕床生厭倦 時間: 2025-3-26 09:27
https://doi.org/10.1007/978-3-658-07452-4entral roles in tumour progression and resistance to cytotoxic chemotherapy and radiotherapy. While many molecular targets may offer synthetic lethal interactions with hypoxia, the development of prodrugs that are activated to generate cytotoxins by one-electron (1e) reduction in hypoxic cells repre作者: exclamation 時間: 2025-3-26 14:15 作者: debouch 時間: 2025-3-26 16:58 作者: 逃避系列單詞 時間: 2025-3-26 22:10 作者: 中和 時間: 2025-3-27 02:32
https://doi.org/10.1007/978-3-0348-6639-2ncreasing number of novel agents that target the DDR have been described and some are already undergoing clinical testing. Evidence from preclinical studies suggests that the use of some of these agents would be effective at targeting tumor cells in hypoxic regions.作者: enmesh 時間: 2025-3-27 05:45 作者: ANT 時間: 2025-3-27 12:15 作者: 試驗 時間: 2025-3-27 17:31
Wie aus Begriffen Bilder werden,m hypoxic manipulation using techniques such as gene expression profiling and functional imaging in order to enrich trial populations with appropriate patients. The use of dynamic monitoring of changes in hypoxia occurring throughout treatment will be needed to exploit microenvironmental changes induced by therapy.作者: 期滿 時間: 2025-3-27 19:38
Hypoxia and Breast Cancer Metastasisession through the transcriptional activation of target genes in BCCs, lymphatic vessels, blood vessels, and supporting stromal cells within the primary tumor. Finally, we discuss the pharmacological inhibition of HIFs as a novel therapeutic approach to block breast cancer metastasis and improve patient survival.作者: Ingratiate 時間: 2025-3-27 23:43
Clinical Exploitation of Hypoxiam hypoxic manipulation using techniques such as gene expression profiling and functional imaging in order to enrich trial populations with appropriate patients. The use of dynamic monitoring of changes in hypoxia occurring throughout treatment will be needed to exploit microenvironmental changes induced by therapy.作者: Fraudulent 時間: 2025-3-28 04:24
https://doi.org/10.1007/978-3-8274-2454-9umor gene expression revealed by the analysis of the transcriptome of the tumor mass provides a global view of the hypoxic status of the tissue. The global and analytic assessment of tumor hypoxia, revealed by the whole tumor mass or by its individual components, will be discussed with particular emphasis on tumor-infiltrating leukocytes.作者: Cabg318 時間: 2025-3-28 07:53
Hypoxia and Gene Expressionumor gene expression revealed by the analysis of the transcriptome of the tumor mass provides a global view of the hypoxic status of the tissue. The global and analytic assessment of tumor hypoxia, revealed by the whole tumor mass or by its individual components, will be discussed with particular emphasis on tumor-infiltrating leukocytes.作者: critic 時間: 2025-3-28 12:11
Book 2014xia and/or anoxia) in tumor tissues. Intra-tumor hypoxia profoundly affects the biological behavior of cancer cells, which become resistant to conventional therapies and acquire a more invasive and metastatic phenotype.?Hypoxia is a hallmark of the malignant phenotype and a key feature of the tumor 作者: confederacy 時間: 2025-3-28 14:43
978-1-4939-5355-4Springer Science+Business Media New York 2014作者: 監(jiān)禁 時間: 2025-3-28 21:43 作者: 結(jié)合 時間: 2025-3-29 00:28
https://doi.org/10.1007/978-1-4614-9167-5cancer; microenvironment; tumor hypoxia作者: subordinate 時間: 2025-3-29 05:42 作者: Fillet,Filet 時間: 2025-3-29 10:13 作者: 在前面 時間: 2025-3-29 11:26
Wie Unternehmen sich selbst erneuernchondrial metabolism, angiogenesis, differentiation, DNA damage response, and cell survival. Such targets are suspected to affect the development of tumors in multiple ways; therefore, an increased knowledge about miR-210’s actions may lead to novel diagnostic and therapeutic approaches in the cance作者: 一再煩擾 時間: 2025-3-29 16:17 作者: 幾何學(xué)家 時間: 2025-3-29 21:08 作者: 流眼淚 時間: 2025-3-30 01:04
Wie arbeite ich mit dem Commodore 128t is through these imaging methods that a clearer picture will develop of the global consequences of oxygen depletion on neoplastic tissue in regard to the basic science of cellular signaling and protein expression. Defining, manipulating, and studying these hypoxia-induced molecular pathways experi作者: nonplus 時間: 2025-3-30 06:37
Aufbau von Datenverarbeitungsanlagen,ccurately and reliably image hypoxia in tumours, especially using techniques that are routinely available in the clinic, such as positron emission tomography, magnetic resonance and computer tomography. The aim of this review is to critically assess the potential use of imaging to monitor hypoxia an作者: 意外的成功 時間: 2025-3-30 10:33 作者: Fretful 時間: 2025-3-30 12:24
Die Kr?hen , Kurzfristige Beratungserfolgehronic hypoxia. This review summarizes the important aspects of UPR signaling and the role of the UPR in determining tumor cell survival or death under hypoxic stress. We also discuss novel pharmacological approaches for targeting critical UPR components as potential anti-tumor strategies.作者: 詳細目錄 時間: 2025-3-30 19:12 作者: 搏斗 時間: 2025-3-30 22:40
