標(biāo)題: Titlebook: G Protein-Coupled Receptors; Immobilization and A Xinfeng Zhao,Qian Li,Jia Quan Book 2023 The Author(s), under exclusive license to Springe [打印本頁] 作者: duodenum 時間: 2025-3-21 17:37
書目名稱G Protein-Coupled Receptors影響因子(影響力)
作者: 圣人 時間: 2025-3-21 20:21
Xinfeng Zhao,Qian Li,Jia QuanDescribes progress in functional immobilization of G protein-coupled receptor.Addresses pharmacological parameters in protein-drug interactions.Reviews the applications of protein immobilization作者: Intrepid 時間: 2025-3-22 02:30 作者: Indict 時間: 2025-3-22 05:56 作者: BOOR 時間: 2025-3-22 09:27
,Wordsworth’s ‘Leveling’ Muse in 1798,sirable way to immobilize GPCRs on solid surfaces is oriented immobilization. In this way, the receptors can be optimal in their orientation, conformation, and activity or functional studies. In this chapter, we review the affinity-based non-covalent and site-specific covalent immobilization methods作者: amnesia 時間: 2025-3-22 14:05
The Informal Logic of Mathematical Proof,ts in practice. This makes it critical to fundamental research of understanding biological processes and the efforts to develop new therapeutic molecules. In this chapter, we summarize several key biochemical parameters, such as binding affinity and kinetics, dynamic conformational ensembles of drug作者: amnesia 時間: 2025-3-22 20:58
https://doi.org/10.1007/978-3-642-73589-9f additional examples of new approaches and/or applications for decoding the interaction between drugs and GPCRs have appeared. In this chapter, we present some of the reports using immobilized GPCRs for drug-receptor interaction analysis, including labelled and label-free assays.作者: 虛構(gòu)的東西 時間: 2025-3-22 22:47
180 Keywords Geld- und W?hrungsrechtpound libraries and natural product extracts are the widely used two sources for bioactive compound screening. In this chapter, we aim to review some representative immobilized GPCR-based methods for the discovery of the bioactive compounds targeting the receptors, which may provide insight into the作者: 白楊 時間: 2025-3-23 04:37 作者: GLUE 時間: 2025-3-23 08:18 作者: 尊嚴(yán) 時間: 2025-3-23 13:01
180 Keywords Geld- und W?hrungsrechtpound libraries and natural product extracts are the widely used two sources for bioactive compound screening. In this chapter, we aim to review some representative immobilized GPCR-based methods for the discovery of the bioactive compounds targeting the receptors, which may provide insight into the high throughput screening of lead compounds.作者: 淺灘 時間: 2025-3-23 15:18
G Protein-Coupled Receptors, is of?paramount importance for drug discovery. This chapter summarizes the structures, conformations, and signaling pathways of different GPCRs, providing an overview of GPCRs for drug discovery purposes.作者: dearth 時間: 2025-3-23 21:35 作者: menopause 時間: 2025-3-23 23:36 作者: inveigh 時間: 2025-3-24 05:47
978-981-99-0077-0The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2023作者: Truculent 時間: 2025-3-24 08:28
G Protein-Coupled Receptors978-981-99-0078-7Series ISSN 2191-5407 Series E-ISSN 2191-5415 作者: ciliary-body 時間: 2025-3-24 12:31
2191-5407 ons.Reviews the applications of protein immobilizationThis book summarizes the progress made to functional immobilize G protein-coupled receptors (GPCRs) through site-specific or orientated recognition in both non-covalent and covalent manners. The last decade is the dawn of the “post-structural bio作者: 樹木心 時間: 2025-3-24 15:51 作者: inchoate 時間: 2025-3-24 22:50
The Informal Logic of Mathematical Proof,les. In this chapter, we summarize several key biochemical parameters, such as binding affinity and kinetics, dynamic conformational ensembles of drug targets, drug resistance time, rebinding, binding thermodynamics, and ligand efficiency.作者: 抵押貸款 時間: 2025-3-25 02:52
https://doi.org/10.1007/978-3-642-72830-3abilization of GPCR using different detergents and styrene-maleic acid–lipid particles. We also highlight the commonly used purification techniques for GPCRs?in literature. Finally, the heterologous expression systems for GPCRs, ranging from bacteria and yeasts to insects, mammalian cells, and ., and the successful purification cases are reviewed.作者: seroma 時間: 2025-3-25 04:00
Purification of G Protein-Coupled Receptors,abilization of GPCR using different detergents and styrene-maleic acid–lipid particles. We also highlight the commonly used purification techniques for GPCRs?in literature. Finally, the heterologous expression systems for GPCRs, ranging from bacteria and yeasts to insects, mammalian cells, and ., and the successful purification cases are reviewed.作者: LEVER 時間: 2025-3-25 10:36
Oriented Immobilization of G Protein-Coupled Receptors,tion, and activity or functional studies. In this chapter, we review the affinity-based non-covalent and site-specific covalent immobilization methods developed for capturing GPCR on solid surfaces. The . and . of each method are also discussed.作者: 稀釋前 時間: 2025-3-25 12:45
Key Biochemical Aspects of Drug-Target Interactions,les. In this chapter, we summarize several key biochemical parameters, such as binding affinity and kinetics, dynamic conformational ensembles of drug targets, drug resistance time, rebinding, binding thermodynamics, and ligand efficiency.作者: 破裂 時間: 2025-3-25 16:12
Book 2023 both non-covalent and covalent manners. The last decade is the dawn of the “post-structural biology” era for G protein-coupled receptor research. As an emerging approach for state-of-the-art immobilization, this book discusses efforts to explore the elegance of naturally-occurring biochemical react作者: 殖民地 時間: 2025-3-25 21:28 作者: 搜尋 時間: 2025-3-26 01:12 作者: 容易生皺紋 時間: 2025-3-26 06:48 作者: 種屬關(guān)系 時間: 2025-3-26 12:27 作者: Console 時間: 2025-3-26 13:40
Immobilized GPCRs in Drug-Receptor Interaction Analysis,f additional examples of new approaches and/or applications for decoding the interaction between drugs and GPCRs have appeared. In this chapter, we present some of the reports using immobilized GPCRs for drug-receptor interaction analysis, including labelled and label-free assays.作者: Hot-Flash 時間: 2025-3-26 18:24
Immobilized GPCRs in Compound Screening,pound libraries and natural product extracts are the widely used two sources for bioactive compound screening. In this chapter, we aim to review some representative immobilized GPCR-based methods for the discovery of the bioactive compounds targeting the receptors, which may provide insight into the作者: HEPA-filter 時間: 2025-3-26 23:26 作者: frozen-shoulder 時間: 2025-3-27 04:25
Book 2023advantages are analyzed for different immobilization methods, and a perspective for future directions is presented. Given its scope, this book appeals to a broad readership, particularly researchers engaged in the field of analytical chemistry, bioconjugate chemistry, and chemical biology, and other作者: 不規(guī)則的跳動 時間: 2025-3-27 07:12
Book 2008staatlicher Inklusion dem neoli- ralen Treiben mit skandalisierenden Konzepten entgegenstemmen zu wollen. Auch manche achselzuckende Reaktion kann diesem Buch gewiss sein, wenn etwa entgegen gehalten wird, Ausschluss habe es schlie?lich immer schon gegeben und die volle Integration sei nur ein - dachter Idealzustand gewesen.作者: 慌張 時間: 2025-3-27 11:37 作者: 反感 時間: 2025-3-27 15:52
,Genotype–Phenotype of , Mutations: A Reference Guide for Gene Testing and Its Clinical Application,a, choroideremia, or vitelliform macular dystrophy with incomplete penetrance. Mutations identified in families with biallelic . mutations included missense (113/200 [56.5%]), frameshift indel (39/200 [19.5%]), splicing defect (24/200 [12.0%]), nonsense (19/200 [9.5%]), inframe indel (4/200 [2.0%]),作者: Blood-Vessels 時間: 2025-3-27 21:01 作者: lymphedema 時間: 2025-3-28 01:03
Two-Person Bargaining Games,in characteristic function form have been evaluated at the Bonn Laboratory of Experimental Economics. Some of the theoretical questions posed by this body of data already arise in two-person games. The experimental literature on two-person games does not offer a well supported descriptive theory.作者: 治愈 時間: 2025-3-28 05:32 作者: slipped-disk 時間: 2025-3-28 06:24
Geriatric Urology and Aging Societies,ture in dance and music are discussed. This research work has been supported by the EU IST project MEGA (Multisensory Expressive Gesture Applications, www.megaproject.org) and the EU MOSART TMR Network.
