作者: abolish 時間: 2025-3-21 23:35
The Extracellular Matrix Goes -Omics: Resources and Tools,including genetic diseases are highlighted in the second part of the chapter. The accessibility and standardization of -omic data are a prerequisite for the FAIR (Findability, Accessibility, Interoperability, and Reusability) guiding principles for scientific data management.作者: GRUEL 時間: 2025-3-22 01:47 作者: 易于出錯 時間: 2025-3-22 07:57 作者: malign 時間: 2025-3-22 09:12
Historical Overview of Integrated GAG-omics and Proteomics,logical mechanisms to inform development of disease therapies and regenerative medicine. In this chapter, we provide a historical overview of our groups’ methods for glycomics, glycoproteomics, and proteomics of key ECM constituents, i.e., GAGs and PGs, as reported over the past decade.作者: Osteoarthritis 時間: 2025-3-22 13:29 作者: Osteoarthritis 時間: 2025-3-22 19:25 作者: Minatory 時間: 2025-3-23 00:18
Proteomic and Degradomic Analysis of Body Fluids: Applications, Challenges and Considerations,(MS), MS-based proteomics is deemed to be the most suitable methodology for systematic analysis of body fluid proteomes. In this chapter, we discuss different body fluids and their characteristics, advancements in MS and workflows suitable for body fluid analysis as well as sample preparation and ap作者: 只有 時間: 2025-3-23 01:22
https://doi.org/10.1007/978-1-4684-5724-7including genetic diseases are highlighted in the second part of the chapter. The accessibility and standardization of -omic data are a prerequisite for the FAIR (Findability, Accessibility, Interoperability, and Reusability) guiding principles for scientific data management.作者: STIT 時間: 2025-3-23 07:33
Martin R. Fulford,Nikolai R. Stankiewiczthat have combined protein-sequence analysis and knowledge-based curation to define the matrisome of model organisms. Last, we provide examples of how the definition of the matrisome has facilitated the identification of ECM genes and proteins in –omic datasets and has advanced our understanding of 作者: Nucleate 時間: 2025-3-23 09:52
Infection Control in the ICU Environmentimmense chemical diversity, typically carries a strong net negative charge which can be exploited to advantage for affinity-isolation and enrichment of proteoglycans from any biological system in a core protein-, GAG-, tissue-, and species-agnostic manner by anion exchange chromatography. This metho作者: Inscrutable 時間: 2025-3-23 14:10 作者: COKE 時間: 2025-3-23 18:10 作者: 表示向下 時間: 2025-3-24 00:47 作者: MURAL 時間: 2025-3-24 04:39 作者: 約會 時間: 2025-3-24 07:47 作者: 字謎游戲 時間: 2025-3-24 14:41
https://doi.org/10.1007/978-3-030-58330-9Extracellular matrix; Quantitative proteomics; Matrisome; Matrisomics; Proteomics; Degradomics; Interactom作者: Fresco 時間: 2025-3-24 16:28
https://doi.org/10.1007/978-1-4684-5724-7lular organisms. It provides structural and mechanical properties to tissues. It also exerts signaling roles, either directly by interacting with cell surface receptors, or by interacting with growth factors and modulating their signaling activities, and by doing so regulates a multitude of cellular作者: Reverie 時間: 2025-3-24 21:09 作者: Parallel 時間: 2025-3-25 02:34 作者: pantomime 時間: 2025-3-25 07:03
Infection Control in the ICU Environmentpy a unique niche in biology. They have varied and essential roles as structural and regulatory molecules in numerous physiological processes and disease pathology. In regard to cellular context, some link the interior of the cell to the extracellular matrix (ECM) as transmembrane or membrane-anchor作者: bromide 時間: 2025-3-25 10:28
https://doi.org/10.1007/978-3-030-57317-1oteoglycans (PGs). GAGs and PGs play vital roles in?ECM-related processes such as cell migration, proliferation, adhesion, and differentiation. Among the . technologies, including genomics, transcriptomics, and proteomics, glycomics is the least mature. Over the past two decades, with efforts from g作者: 產(chǎn)生 時間: 2025-3-25 13:04
https://doi.org/10.1007/978-3-319-20669-1Ricard-Blum, Cold Spring Harb Perspect Biol 3:a004978, 2011), glycosaminoglycans (GAGs) and proteoglycans (PGs) (Iozzo and Schaefer, Matrix Biol 42:11–55, 2015; Karamanos et al., Chem Rev 118:9152–9232, 2018). We review here the major methods used to identify and characterize ECM protein, glycosamin作者: dysphagia 時間: 2025-3-25 18:56 作者: pester 時間: 2025-3-25 21:00
Local Delivery of Antibiotic and Antiseptic and organs and to contain a vast pool of candidate biomarkers for a wide range of conditions. Thus, body fluids are regarded as highly attractive specimens for detecting disease disposition, to monitor markers of progression or to assess the efficacy of treatments. They provide several advantages f作者: medium 時間: 2025-3-26 01:51
The Eye as a Model for Immune Privilege,ation, and migration. Cell-matrix interactions are mediated by integrin-associated adhesion complexes, multiprotein complexes of intracellular scaffolding and signalling proteins that link the cytoskeleton to the extracellular milieu. These linkages enable cells to sense and respond to the biochemic作者: 樹上結(jié)蜜糖 時間: 2025-3-26 05:16
https://doi.org/10.1007/978-94-009-0077-6e variety of molecules including proteins, proteglycans and glycoaminoglycans. It contributes to cell signaling through the action of both its constituents and their proteolytic cleaved fragments called matricryptins. In addition, ECM acts as a “reservoir” of growth factors and cytokines and regulat作者: Eclampsia 時間: 2025-3-26 08:49
978-3-030-58332-3Springer Nature Switzerland AG 2020作者: 重疊 時間: 2025-3-26 13:38 作者: CHASE 時間: 2025-3-26 17:09
Sylvie Ricard-BlumProvides a state-of-the art overview of extracellular matrix omics.Focuses especially on glycomics and glycobioinformatics.Elaborates on guiding principles for scientific data management作者: Interstellar 時間: 2025-3-27 00:33 作者: 得罪人 時間: 2025-3-27 02:55
0887-3224 ding principles for scientific data management.This book covers different omics aspects related to the extracellular matrix (ECM), namely specific omics resources focused on the extracellular matrix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellula作者: 致命 時間: 2025-3-27 05:16
Book 2020ix (e.g., databases, repositories and atlases), quantitative proteomics applied to specific extracellular matrices (e.g. basement membranes), biological processes such as ECM degradation (degradomics), cell-matrix interactions (adhesomes), signaling pathways, biomarker discovery and diseases, and in作者: Esophagus 時間: 2025-3-27 11:25 作者: crumble 時間: 2025-3-27 15:21 作者: indigenous 時間: 2025-3-27 19:49 作者: Cougar 時間: 2025-3-27 22:01
Detecting Changes to the Extracellular Matrix in Liver Diseases,ibute to disease progression. The purpose of this review is to summarize the established and proposed changes to the hepatic extracellular matrix (ECM) that may contribute to inflammation during earlier stages of disease development, and to discuss potential mechanisms by which these changes may mediate the progression of the disease.作者: 易怒 時間: 2025-3-28 03:05 作者: 廣大 時間: 2025-3-28 08:37
,Integrative Models for TGF-β Signaling and Extracellular Matrix,, proliferation, migration, etc.)..In this context, signaling networks associated with the polypeptide transforming growth factor TGF-β are unique since their activation are controlled by ECM and TGF-β is a major regulator of ECM remodeling in return.作者: resistant 時間: 2025-3-28 13:04
The Extracellular Matrix Goes -Omics: Resources and Tools,lular organisms. It provides structural and mechanical properties to tissues. It also exerts signaling roles, either directly by interacting with cell surface receptors, or by interacting with growth factors and modulating their signaling activities, and by doing so regulates a multitude of cellular作者: 身心疲憊 時間: 2025-3-28 17:18 作者: 通便 時間: 2025-3-28 21:51 作者: floaters 時間: 2025-3-29 00:26
Characterization of Proteoglycanomes by Mass Spectrometry,py a unique niche in biology. They have varied and essential roles as structural and regulatory molecules in numerous physiological processes and disease pathology. In regard to cellular context, some link the interior of the cell to the extracellular matrix (ECM) as transmembrane or membrane-anchor作者: nonplus 時間: 2025-3-29 07:04
Historical Overview of Integrated GAG-omics and Proteomics,oteoglycans (PGs). GAGs and PGs play vital roles in?ECM-related processes such as cell migration, proliferation, adhesion, and differentiation. Among the . technologies, including genomics, transcriptomics, and proteomics, glycomics is the least mature. Over the past two decades, with efforts from g作者: 笨拙的你 時間: 2025-3-29 10:42
Extracellular Matrix Networks: From Connections to Functions,Ricard-Blum, Cold Spring Harb Perspect Biol 3:a004978, 2011), glycosaminoglycans (GAGs) and proteoglycans (PGs) (Iozzo and Schaefer, Matrix Biol 42:11–55, 2015; Karamanos et al., Chem Rev 118:9152–9232, 2018). We review here the major methods used to identify and characterize ECM protein, glycosamin
