標(biāo)題: Titlebook: Erythrocytes as Drug Carriers in Medicine; Ulrich Sprandel,James L. Way Book 1997 Springer Science+Business Media New York 1997 blood.clin [打印本頁] 作者: 表范圍 時(shí)間: 2025-3-21 18:26
書目名稱Erythrocytes as Drug Carriers in Medicine影響因子(影響力)
書目名稱Erythrocytes as Drug Carriers in Medicine影響因子(影響力)學(xué)科排名
書目名稱Erythrocytes as Drug Carriers in Medicine網(wǎng)絡(luò)公開度
書目名稱Erythrocytes as Drug Carriers in Medicine網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Erythrocytes as Drug Carriers in Medicine被引頻次
書目名稱Erythrocytes as Drug Carriers in Medicine被引頻次學(xué)科排名
書目名稱Erythrocytes as Drug Carriers in Medicine年度引用
書目名稱Erythrocytes as Drug Carriers in Medicine年度引用學(xué)科排名
書目名稱Erythrocytes as Drug Carriers in Medicine讀者反饋
書目名稱Erythrocytes as Drug Carriers in Medicine讀者反饋學(xué)科排名
作者: 軟膏 時(shí)間: 2025-3-21 21:30
,Quarterly Forecast for 2019–2020,e phosphorylation depends on specific cellular kinases whose levels in turn depend on the activation state of the target cells and on the cell types (5). Usually, quiescent cells have low levels of the enzymes responsible for nucleoside analogue phosphorylation, while activation (e.g., mitogen stimu作者: Verify 時(shí)間: 2025-3-22 00:59
Lorenzo Riccardi,Giorgio Riccardiion. Unfortunately, the efficacy of drugs so far used in monotherapy is of limited duration while a number of preliminary studies have already shown that combination therapy is more effective than monotherapy (8, 9). Combination therapy may provide additive or synergistic effect of combined drugs, d作者: 獸皮 時(shí)間: 2025-3-22 06:32 作者: Exonerate 時(shí)間: 2025-3-22 09:25
https://doi.org/10.1007/978-981-13-2727-8on the action of crosslinking reagents which react with band 3 in mouse erythrocyte membrane. Additionally, biotinylation of mouse erythrocytes has been studied. “.” behaviour of these chemically modified erythrocytes have been studied. These survival results have been compared to recognition by mac作者: ATRIA 時(shí)間: 2025-3-22 15:52
Erythrocyte-Based Targeted Release to Macrophages of an Azidothymidine Homodinucleotide Prevents Reion was observed with human, feline and murine macrophages against infection by HIV-1, FIV and LP-BM5 retroviral strains, respectively. These data demonstrate that AZT.AZT-loaded and opsonized erythrocytes represent an efficient “trojan horse” resulting in significant protection of macrophages from 作者: ATRIA 時(shí)間: 2025-3-22 19:14
Macrophage Protection by Nucleoside and Nucleotide Analogue Administration,e phosphorylation depends on specific cellular kinases whose levels in turn depend on the activation state of the target cells and on the cell types (5). Usually, quiescent cells have low levels of the enzymes responsible for nucleoside analogue phosphorylation, while activation (e.g., mitogen stimu作者: 有特色 時(shí)間: 2025-3-22 21:28
Inhibition of Murine AIDS by Combination of AZT and DDCTP-Loaded Erythrocytes,ion. Unfortunately, the efficacy of drugs so far used in monotherapy is of limited duration while a number of preliminary studies have already shown that combination therapy is more effective than monotherapy (8, 9). Combination therapy may provide additive or synergistic effect of combined drugs, d作者: 施魔法 時(shí)間: 2025-3-23 04:23 作者: 變量 時(shí)間: 2025-3-23 09:28 作者: metropolitan 時(shí)間: 2025-3-23 10:00 作者: 密切關(guān)系 時(shí)間: 2025-3-23 14:40 作者: 集合 時(shí)間: 2025-3-23 21:05 作者: 使人煩燥 時(shí)間: 2025-3-24 00:31
Organophosphorus Antagonism by Resealed Erythrocytes Containing Recombinant Paraoxonase,protection greatly exceeds any antidotal regimen ever reported against chemical toxicants. The present drug carrier model provides a general conceptual approach to develop specific antidotes against many other chemical toxicants for which no antidotes are presently available.作者: frenzy 時(shí)間: 2025-3-24 05:30
Biochemical Properties of Alcohol Dehydrogenase and Glutamate Dehydrogenase Encapsulated into Humanhyde by ADH-RBCs, as a function of time (up to 72h), suggest the use of these carrier RBCs to fully metabolize ethanol. The rapid utilization of ammonia in the presence of GDH-RBCs suggest the use of these RBCs as carrier systems. These properties open the possibility of using ADH- and GDH-RBCs as carrier systems under . situations.作者: originality 時(shí)間: 2025-3-24 06:40
Binding of Daunorubicin and Doxorubicin to Erythrocytes Treated with Glutaraldehyde,dily released from these erythrocytes in the antibiotic-free medium. Our findings provide evidence that immobilization of anthracycline antibiotics in the erythrocytes using glutaraldehyde treatment is connected with the chemical binding of the antibiotics to different erythrocyte components.作者: Synthesize 時(shí)間: 2025-3-24 13:13 作者: 歌曲 時(shí)間: 2025-3-24 16:28 作者: 能得到 時(shí)間: 2025-3-24 21:15 作者: 殘暴 時(shí)間: 2025-3-25 00:00
d is due to a deficiency of glucocerebrosidase. An absence of glucocereobrosidase results in an accumulation of glucocere-broside within the macrophages of the reticulo-endothelial system in the spleen, liver and bone marrow to produce Gaucher cells which are characteristic of this disorder.作者: 大暴雨 時(shí)間: 2025-3-25 06:08
Lincoln Bizzozero Revelez,Andrés Raggiots in increased production of reactive oxygen metabolites and nitric oxide, increased phagocytic uptake, and release of many cytokines including IL-1, IL-6, TNF-α and growth factors (M-CSF, G-CSF). Upon activation macrophages also release lipid mediators (prostaglandins and leukotrienes) and numerous enzymes (1).作者: Pageant 時(shí)間: 2025-3-25 10:21 作者: 錢財(cái) 時(shí)間: 2025-3-25 14:47 作者: hankering 時(shí)間: 2025-3-25 18:52 作者: Inscrutable 時(shí)間: 2025-3-25 22:55
https://doi.org/10.1007/978-3-658-17651-8(EC 2.7.1.20) is lower than that of ADA. Adenosine in excess of physiological levels is degraded by ADA. The major source of 2′-deoxyadenosine is DNA turnover and the main route of its metabolism is deamination by ADA.作者: 眉毛 時(shí)間: 2025-3-26 01:31
Der japanische Zugriff: Trauma #5nd a slow conversion to 5′-monophosphate (AZT-MP) and to AZT. This azidothymidine homodinucleotide seems to have chemical and biochemical properties enabling its profitable utilization in the erythrocyte-encapsulated form.作者: GUMP 時(shí)間: 2025-3-26 07:22
bility (as given by the oxygen equilibrium curves) suggest the electroporation/resealing process as a convenient alternative to the hypotonic-dialysis method for the preparation of ADH- and ALDH-erythrocytes.作者: institute 時(shí)間: 2025-3-26 11:09 作者: 胎兒 時(shí)間: 2025-3-26 15:00 作者: pancreas 時(shí)間: 2025-3-26 20:27
The Entrapment of Polyethylene Glycol-Conjugated Adenosine Deaminase (Pegademase) and Native Adenos(EC 2.7.1.20) is lower than that of ADA. Adenosine in excess of physiological levels is degraded by ADA. The major source of 2′-deoxyadenosine is DNA turnover and the main route of its metabolism is deamination by ADA.作者: gene-therapy 時(shí)間: 2025-3-27 01:01 作者: 任意 時(shí)間: 2025-3-27 04:24
Encapsulation of Alcohol Dehydrogenase and Acetaldehyde Dehydrogenase into Human Erythrocytes by anbility (as given by the oxygen equilibrium curves) suggest the electroporation/resealing process as a convenient alternative to the hypotonic-dialysis method for the preparation of ADH- and ALDH-erythrocytes.作者: 媽媽不開心 時(shí)間: 2025-3-27 08:42
The Entrapment of Mannose-Terminated Glucocerebrosidase (Alglucerase) in Human Carrier Erythrocytesd is due to a deficiency of glucocerebrosidase. An absence of glucocereobrosidase results in an accumulation of glucocere-broside within the macrophages of the reticulo-endothelial system in the spleen, liver and bone marrow to produce Gaucher cells which are characteristic of this disorder.作者: 搏斗 時(shí)間: 2025-3-27 10:15 作者: stress-test 時(shí)間: 2025-3-27 16:02 作者: 靦腆 時(shí)間: 2025-3-27 20:47
https://doi.org/10.1007/978-981-16-4534-1protection greatly exceeds any antidotal regimen ever reported against chemical toxicants. The present drug carrier model provides a general conceptual approach to develop specific antidotes against many other chemical toxicants for which no antidotes are presently available.作者: Commodious 時(shí)間: 2025-3-27 22:20
,Quarterly Forecast for 2017–18,hyde by ADH-RBCs, as a function of time (up to 72h), suggest the use of these carrier RBCs to fully metabolize ethanol. The rapid utilization of ammonia in the presence of GDH-RBCs suggest the use of these RBCs as carrier systems. These properties open the possibility of using ADH- and GDH-RBCs as carrier systems under . situations.作者: 小官 時(shí)間: 2025-3-28 02:56
Energy Security: Perceptions and Realities,dily released from these erythrocytes in the antibiotic-free medium. Our findings provide evidence that immobilization of anthracycline antibiotics in the erythrocytes using glutaraldehyde treatment is connected with the chemical binding of the antibiotics to different erythrocyte components.作者: 富饒 時(shí)間: 2025-3-28 09:50
Bhabani Shankar Nayak,Huaihua Lairance from circulation. Erythrocytes (RBC) coated with recombinant interleukin 2 (rIL2) provide a means of delivering IL2 into the system in a continuous, low dose manner which in turn maintains a low, potentially non-toxic, IL2 concentration. Murine RBC coated with rIL2 (RBC-rIL2) induce cytotoxici作者: 某人 時(shí)間: 2025-3-28 13:25 作者: 沖擊力 時(shí)間: 2025-3-28 15:28
Chinas Industriepolitik von 1978-2013mean cell life range of 89 to 131 days (normal half-life of 19 to 29 days) should limit the vascular clearance of the administered drug thus reducing the dosage and frequency of therapeutic interventions.作者: 戰(zhàn)役 時(shí)間: 2025-3-28 21:05 作者: 英寸 時(shí)間: 2025-3-29 02:38
Gerhard Preyer,Reu?-Markus Krau?eell defined. Due to their physiological role, they have access to most parts of the body. If transfusion rules are respected they are neither toxic nor immunogenic, and finally they are biodegradable. As largely demonstrated in the past, these properties allow them to be used as drug carriers in imp作者: 嘮叨 時(shí)間: 2025-3-29 04:10
Der japanische Zugriff: Trauma #5ome some limitations of conventional antiretroviral chemotherapy based upon nucleoside analogues (AZT, ddC, ddI). Indeed, the triphosphorylated form of these nucleoside analogues is able to inhibit the infectivity and replication of Human Immunodeficiency Virus (HIV-1), but the main problems in the 作者: Gudgeon 時(shí)間: 2025-3-29 09:33 作者: Moderate 時(shí)間: 2025-3-29 12:50 作者: evanescent 時(shí)間: 2025-3-29 19:32 作者: Foment 時(shí)間: 2025-3-29 20:33 作者: 征兵 時(shí)間: 2025-3-30 01:00 作者: ESO 時(shí)間: 2025-3-30 07:44
https://doi.org/10.1007/978-981-16-4534-1cation of paraoxon, the active metabolite of parathion, by using resealed carrier erythrocytes containing a highly purified recombinant paraoxonase (CRBC). The CRBC were found to be effective alone and synergistic with 2-PAM and atropine to protect over 1,000 lethal doses of paraoxon. This striking 作者: pellagra 時(shí)間: 2025-3-30 08:13 作者: LEVY 時(shí)間: 2025-3-30 14:35
,Quarterly Forecast for 2017–18, free enzyme solutions. Encapsulation into RBCs suggest a protective effect of both enzyme activities. An efflux of the encapsulated enzymes from the carrier RBCs was observed during a similar incubation. The continuous degradation of ethanol and the simultaneous appearance/disappearance of acetalde作者: 中子 時(shí)間: 2025-3-30 17:31
https://doi.org/10.1007/978-981-13-2727-8logical method to convey and deliver active compounds.. The preparation of erythrocytes as carriers can require encapsulation procedures or/and chemical modification of erythrocyte surface.. In fact, the efficacy of these systems can be dependent of the use of several chemical treatments which can r作者: 預(yù)防注射 時(shí)間: 2025-3-30 23:47 作者: 脫毛 時(shí)間: 2025-3-31 02:54
tes were first established (37oC, 300V, 1ms pulse time, 8 pulses every 15min, and 1h resealing). At a fixed enzyme level (100U ADH or 3U ALDH per mL erythrocyte suspension), the encapsulation yield was 26.2% for ADH and 38.3% for ALDH. Carrier cell recoveries were 82–85%. Cell volumes increase while作者: 四牛在彎曲 時(shí)間: 2025-3-31 08:51
China‘s Agriculture at the Cross Roadsers. Homologous or autologous erythrocytes were loaded with doxorubicin aseptically by their incubation at 37°C in the solution of doxorubicin for 1 h. During the i.v. infusion of doxorubicin in solution (25–50 mg per square meter of body surface area), its concentration in blood rose to 3.60–5.90 u作者: Charitable 時(shí)間: 2025-3-31 12:03
Energy Security: Perceptions and Realities,tibiotic. Bound antibiotics can be immobilized in the erythrocytes using glutaraldehyde treatment. It was found, however, that erythrocytes pretreated with glutaraldehyde can uptake daunorubicin and doxorubicin from the incubation medium and do it faster than untreated cells. The antibiotics are rea作者: 不遵守 時(shí)間: 2025-3-31 16:24 作者: indemnify 時(shí)間: 2025-3-31 21:23
