標(biāo)題: Titlebook: Dynamic-Clamp; From Principles to A Thierry Bal,Alain Destexhe Book 2009 Springer-Verlag New York 2009 Biophysics.Cortex.Neurobiology.Stent [打印本頁(yè)] 作者: Waterproof 時(shí)間: 2025-3-21 19:03
書目名稱Dynamic-Clamp影響因子(影響力)
書目名稱Dynamic-Clamp影響因子(影響力)學(xué)科排名
書目名稱Dynamic-Clamp網(wǎng)絡(luò)公開度
書目名稱Dynamic-Clamp網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Dynamic-Clamp被引頻次
書目名稱Dynamic-Clamp被引頻次學(xué)科排名
書目名稱Dynamic-Clamp年度引用
書目名稱Dynamic-Clamp年度引用學(xué)科排名
書目名稱Dynamic-Clamp讀者反饋
書目名稱Dynamic-Clamp讀者反饋學(xué)科排名
作者: STYX 時(shí)間: 2025-3-21 21:53 作者: antecedence 時(shí)間: 2025-3-22 01:37
Synaptic Conductances and Spike Generation in Cortical Cells,astic and oscillatory network activity can be applied repeatedly and precisely to neurons. In this chapter, I review our work using this approach, addressing the nature of the threshold and of the reliability of spike generation in cortical neurons, how synaptic conductance input patterns are encode作者: 6Applepolish 時(shí)間: 2025-3-22 06:00 作者: 無(wú)價(jià)值 時(shí)間: 2025-3-22 10:09 作者: accordance 時(shí)間: 2025-3-22 14:33
Dynamic-Clamp-Constructed Hybrid Circuits for the Study of Synchronization Phenomena in Networks ofnd in the case of excitation from two special cases, one in which the coupling becomes effectively continuous and another in which complex behavior results from a discontinuous PRC. The firing intervals and network period predictions were generally accurate within 10% of the values actually observed作者: accordance 時(shí)間: 2025-3-22 20:23
Re-Creating In Vivo-Like Activity and Investigating the Signal Transfer Capabilities of Neurons: Dyies. Third, the dynamic-clamp experiments could re-create “in vivo-like” background synaptic activity by injection of stochastic excitatory and inhibitory conductances, and we showed that this activity profoundly modifies the input–output transfer function of thalamic and cortical neurons. We also i作者: Favorable 時(shí)間: 2025-3-22 21:49 作者: cornucopia 時(shí)間: 2025-3-23 03:36
Impact of Background Synaptic Activity on Neuronal Response Properties Revealed by Stepwise Replica作者: HARP 時(shí)間: 2025-3-23 07:18 作者: CESS 時(shí)間: 2025-3-23 10:10
Frank Ahlhorn,Jenny Kebschull,Helge Bormann a cell, as well as the construction of whole hybrid networks in which the biological cell interacts with model cells simulated in real time using a digital or analog system. Many of the applications briefly presented here are the subject of the following chapters.作者: 使腐爛 時(shí)間: 2025-3-23 17:30 作者: Lyme-disease 時(shí)間: 2025-3-23 21:51
https://doi.org/10.1007/978-3-658-42694-1ed “high-conductance” state, thought to occur in vivo, and suggest alternate means by which coherent activity can be generated in the absence of strong cellular oscillations. We close by discussing future developments that will increase the utility and widespread use of the dynamic-clamp method.作者: 散布 時(shí)間: 2025-3-24 00:53 作者: Restenosis 時(shí)間: 2025-3-24 05:15 作者: 連詞 時(shí)間: 2025-3-24 07:23
ies. Third, the dynamic-clamp experiments could re-create “in vivo-like” background synaptic activity by injection of stochastic excitatory and inhibitory conductances, and we showed that this activity profoundly modifies the input–output transfer function of thalamic and cortical neurons. We also i作者: FACET 時(shí)間: 2025-3-24 13:38
Associating Living Cells and Computational Models: an Introduction to Dynamic Clamp Principles and talist, activating and inactivating into the membrane of an intracellularly recorded biological cell. Dynamic clamp relies on the establishing of a loop between the injected current and the recorded membrane potential. In this introductory chapter, we first present the principles of the technique, s作者: 走調(diào) 時(shí)間: 2025-3-24 16:18
,Dendritic Dynamic Clamp – A Tool to Study Single Neuron Computation,synaptic input to the site of action potential initiation in the axon. Direct dendritic whole-cell recording techniques have however demonstrated that dendrites are electrically excitable. Recently, the dynamic clamp has been used to simulate synaptic activity at determined dendritic sites in neuron作者: minimal 時(shí)間: 2025-3-24 22:21
Synaptic Conductances and Spike Generation in Cortical Cells,ting membrane potential and spike responses. However, we now have accurate biophysical models of the ionic conductances at the postsynaptic sites of cortical synapses and of the conductances which generate action potentials (APs). Using conductance injection or dynamic clamp, it is possible to injec作者: escalate 時(shí)間: 2025-3-25 02:34 作者: freight 時(shí)間: 2025-3-25 04:44 作者: DEVIL 時(shí)間: 2025-3-25 10:45
Functions of the Persistent Na+ Current in Cortical Neurons Revealed by Dynamic Clamp,ction potential threshold. This current may strongly influence integration and transduction of synaptic input into spike patterns. However, due to the lack of pharmacological tools for selective blockade or enhancement of .., its impact on spike generation has remained enigmatic. By using dynamic cl作者: 擴(kuò)音器 時(shí)間: 2025-3-25 13:19
,Using “Hard” Real-Time Dynamic Clamp to Study Cellular and Network Mechanisms of Synchronization inhinal cortex. We find that “hard” real-time dynamic-clamp systems, characterized by very small maximal errors in timing of feedback, are necessary for cases in which fast voltage-gated channels are being mimicked in experiments. Using a hard real-time system to study cellular oscillations in entorhi作者: xanthelasma 時(shí)間: 2025-3-25 16:26
Unraveling the Dynamics of Deep Cerebellar Nucleus Neurons with the Application of Artificial Condu) to explore how spiking in these neurons is controlled by the interaction of synaptic and intrinsic conductances. Besides the application of synaptic- and voltage-gated conductances, we introduce the modeling of an intracellular calcium pool in the real-time loop of the dynamic clamp in order to ap作者: CHART 時(shí)間: 2025-3-25 20:16
Intrinsic and Network Contributions to Reverberatory Activity: Reactive Clamp and Modeling Studies, in vivo, spontaneously or in response to stimulation. We combined computer simulations and in vitro intracellular recording from prefrontal cortical neurons to explore the elicitation, modulation, and termination of these reverberations. In computer simulations, we studied the reverberating activit作者: output 時(shí)間: 2025-3-26 02:51 作者: BRIBE 時(shí)間: 2025-3-26 07:41
Using the Dynamic Clamp to Explore the Relationship Between Intrinsic Activity and Network Dynamicse propose a novel method using the dynamic clamp to evaluate the intrinsic properties of isolated neurons that replaces conventional methods such as measuring input impedance. Secondly, we construct novel circuits using the dynamic clamp by electrically coupling pairs of pacemakers of rhythmically a作者: evasive 時(shí)間: 2025-3-26 11:32
Re-Creating In Vivo-Like Activity and Investigating the Signal Transfer Capabilities of Neurons: Dyurons, and how these intrinsic properties influence signal integration. More recently, it became clear that the transfer function of neurons also highly depends on the activity of the surrounding network, and in particular on the presence of synaptic background activity. We review here different in 作者: 征兵 時(shí)間: 2025-3-26 13:33 作者: 新星 時(shí)間: 2025-3-26 19:18 作者: Buttress 時(shí)間: 2025-3-26 22:49
Key Factors for Improving Dynamic-Clamp Performance,een written focusing on the performance and reliability of this protocol and how the accuracy of a dynamic-clamp system can be assessed. Here we review the published literature to date, focusing on how experimental, computational, and algorithmic factors contribute to the reliability of the dynamic-作者: SKIFF 時(shí)間: 2025-3-27 03:26
Development of a Genetically Engineered Cardiac Pacemaker: Insights from Dynamic Action Potential C action potential clamp’ (dAPC) technique. This is a technique that we recently developed to study the effects of long-QT syndrome-related ion channel mutations by effectively replacing the associated native ionic current of a cardiac myocyte with wild-type or mutant current recorded from a HEK-293 作者: 原始 時(shí)間: 2025-3-27 05:26 作者: MAUVE 時(shí)間: 2025-3-27 11:22
Springer Series in Computational Neurosciencehttp://image.papertrans.cn/e/image/283817.jpg作者: cyanosis 時(shí)間: 2025-3-27 15:22
Frank Ahlhorn,Jenny Kebschull,Helge Bormanntalist, activating and inactivating into the membrane of an intracellularly recorded biological cell. Dynamic clamp relies on the establishing of a loop between the injected current and the recorded membrane potential. In this introductory chapter, we first present the principles of the technique, s作者: anthropologist 時(shí)間: 2025-3-27 20:42 作者: cardiac-arrest 時(shí)間: 2025-3-28 01:22
Martin Elff,Sigrid Ro?teutscherting membrane potential and spike responses. However, we now have accurate biophysical models of the ionic conductances at the postsynaptic sites of cortical synapses and of the conductances which generate action potentials (APs). Using conductance injection or dynamic clamp, it is possible to injec作者: intricacy 時(shí)間: 2025-3-28 04:28 作者: Neutropenia 時(shí)間: 2025-3-28 08:57
Moritz Leitner,André Klima,Paul W. Thurner methods are derived from a model of synaptic background activity where the synaptic membrane conductances are considered as stochastic processes. Because this . model can be treated analytically, different methods can be outlined to estimate different characteristics of synaptic noise from the memb作者: Acetabulum 時(shí)間: 2025-3-28 13:29 作者: 水槽 時(shí)間: 2025-3-28 18:12 作者: Adenocarcinoma 時(shí)間: 2025-3-28 19:35 作者: 從容 時(shí)間: 2025-3-28 23:30
in vivo, spontaneously or in response to stimulation. We combined computer simulations and in vitro intracellular recording from prefrontal cortical neurons to explore the elicitation, modulation, and termination of these reverberations. In computer simulations, we studied the reverberating activit作者: PIZZA 時(shí)間: 2025-3-29 03:49 作者: Working-Memory 時(shí)間: 2025-3-29 10:17 作者: 泄露 時(shí)間: 2025-3-29 12:55
urons, and how these intrinsic properties influence signal integration. More recently, it became clear that the transfer function of neurons also highly depends on the activity of the surrounding network, and in particular on the presence of synaptic background activity. We review here different in 作者: nuclear-tests 時(shí)間: 2025-3-29 18:34
Peter Lautenbach,Katharina Morlang14?Hz) waves that permeate the brain during sleep and anaesthesia to the faster oscillations in the alpha (α) and beta/gamma (β/γ) (>15?Hz) bands that occur during wakefulness. In recent years, it has been shown that several of these oscillations are associated with intrinsic rhythmic activity in in作者: 伴隨而來 時(shí)間: 2025-3-29 22:39 作者: Affection 時(shí)間: 2025-3-30 00:23
Nils Ukley,Renate Nocon-Stofferseen written focusing on the performance and reliability of this protocol and how the accuracy of a dynamic-clamp system can be assessed. Here we review the published literature to date, focusing on how experimental, computational, and algorithmic factors contribute to the reliability of the dynamic-作者: 難聽的聲音 時(shí)間: 2025-3-30 04:29 作者: 出生 時(shí)間: 2025-3-30 11:45
https://doi.org/10.1007/978-0-387-89279-5Biophysics; Cortex; Neurobiology; Stent; cells; computational neuroscience; neurons; physiology作者: avulsion 時(shí)間: 2025-3-30 14:07
978-1-4419-2790-3Springer-Verlag New York 2009作者: 行業(yè) 時(shí)間: 2025-3-30 18:41 作者: Gossamer 時(shí)間: 2025-3-30 23:29 作者: RLS898 時(shí)間: 2025-3-31 02:20
Book 2009 called “conductance injection”) allows experimentalists and theoreticians to challenge neurons (or any other type of cell) with complex conductance stimuli generated by a computer...The technique can be implemented from neural simulation environments and a variety of custom-made or commercial syste作者: ALIAS 時(shí)間: 2025-3-31 05:27
Massenbewegungen und die Flut im?Ahrtal. Here, I describe the implementation of the dendritic dynamic-clamp technique and review the results of recent experiments using the dendritic dynamic clamp to explore the properties of synaptic integration in the dendrites of cortical pyramidal neurons.作者: faucet 時(shí)間: 2025-3-31 12:36 作者: freight 時(shí)間: 2025-3-31 14:10 作者: Magnitude 時(shí)間: 2025-3-31 20:26
Unraveling the Dynamics of Deep Cerebellar Nucleus Neurons with the Application of Artificial Conduthe effects of focal somatic or distributed dendritic conductances on the spiking behavior of a full morphological DCN neuron model in order to better understand the limitations of dynamic clamping given by applying artificial conductances only at a single location.作者: 捏造 時(shí)間: 2025-4-1 01:12 作者: 令人作嘔 時(shí)間: 2025-4-1 05:25 作者: neolith 時(shí)間: 2025-4-1 08:18
Dynamic Clamp with High-Resistance Electrodes Using Active Electrode Compensation In Vitro and In Vfied and may cause instabilities. We show here that such problems are greatly limited by the AEC, and this technique enables dynamic-clamp injection at high feedback frequencies (>10?kHz) and in demanding conditions. We illustrate AEC with applications such as injection of conductance noise in vivo and in vitro.作者: RENAL 時(shí)間: 2025-4-1 12:46 作者: 怪物 時(shí)間: 2025-4-1 15:56
Moritz Leitner,André Klima,Paul W. Thurnerterns, as we illustrate here. Our approach constitutes a novel application of the dynamic clamp, which could be extended to the testing of other methods for extracting conductance information from the recorded .. activity of neurons.作者: CURL 時(shí)間: 2025-4-1 18:44
