標(biāo)題: Titlebook: Drebrin; From Structure and F Tomoaki Shirao,Yuko Sekino Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license [打印本頁(yè)] 作者: introspective 時(shí)間: 2025-3-21 18:15
書目名稱Drebrin影響因子(影響力)
書目名稱Drebrin影響因子(影響力)學(xué)科排名
書目名稱Drebrin網(wǎng)絡(luò)公開度
書目名稱Drebrin網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Drebrin被引頻次
書目名稱Drebrin被引頻次學(xué)科排名
書目名稱Drebrin年度引用
書目名稱Drebrin年度引用學(xué)科排名
書目名稱Drebrin讀者反饋
書目名稱Drebrin讀者反饋學(xué)科排名
作者: fatty-streak 時(shí)間: 2025-3-21 20:33 作者: Canary 時(shí)間: 2025-3-22 00:57
Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/e/image/282822.jpg作者: Ascendancy 時(shí)間: 2025-3-22 06:49
Multi-sense Attention for Autonomous Agentsein, which is classified into two major isoforms produced by alternative splicing from a single . gene. The isoform predominantly expressed in the adult brain (drebrin A) is neuron specific, containing a neuron-specific sequence (Ins2) in the middle of the molecule. Drebrin A is highly concentrated 作者: 恃強(qiáng)凌弱的人 時(shí)間: 2025-3-22 09:25 作者: Minatory 時(shí)間: 2025-3-22 14:00
https://doi.org/10.1007/978-3-031-04386-4in in vivo, we must understand its molecular properties. In this chapter, I will focus on the purification and characterization of drebrin in vitro. Drebrin binds to F-actin with a stoichiometry of 1:5~6 with a .. of 1~3 × 10. M and strongly inhibits the binding of other actin-binding proteins such 作者: Minatory 時(shí)間: 2025-3-22 17:17 作者: 的闡明 時(shí)間: 2025-3-22 23:12 作者: 豪華 時(shí)間: 2025-3-23 02:56
Nikolaos Karagiannis,Debbie A. Mohammedyclonal and monoclonal antibodies. Immunoblot analysis demonstrated that the adult drebrin isoform (drebrin A) is restricted to neural tissues, while the embryonic drebrin isoforms (drebrin E1 and E2 in chicken and drebrin E in mammals) are found in a wide variety of tissues. In the developing brain作者: 不再流行 時(shí)間: 2025-3-23 07:26
Nikolaos Karagiannis,Debbie A. Mohammedn is an F-actin-binding protein that increases noticeably during juvenile synaptogenesis. Electron microscopic analysis reveals that drebrin is highly enriched specifically on the postsynaptic side of excitatory synapses. Since dendritic spines are structures specialized for excitatory synaptic tran作者: Nonflammable 時(shí)間: 2025-3-23 12:17
https://doi.org/10.1007/978-3-031-06493-7 neurites, axons, and dendrites are important for the formation of functional neuronal circuits. The actin cytoskeleton has major roles in the morphological development of neurons. In this chapter, we focused on the distribution and function of the actin-binding protein, drebrin, to elucidate the im作者: 紅潤(rùn) 時(shí)間: 2025-3-23 15:17
https://doi.org/10.1007/978-3-031-06493-7 a fundamental unit for information processing of the brains. Previous studies have demonstrated the roles of drebrin in the formation of dendritic spines and in the recruitment of synaptic proteins to postsynaptic sites. Further, a live imaging study has revealed the unique dynamics of drebrin in d作者: 剛開始 時(shí)間: 2025-3-23 20:25
https://doi.org/10.1007/978-3-031-06592-7ostsynaptic sites plays a pivotal role in synaptic plasticity. In this chapter, we review the role of drebrin in the regulation of the actin cytoskeleton during synaptic plasticity, under long-term potentiation (LTP) and long-term depression (LTD). Dendritic spines have two F-actin pools, drebrin-de作者: 腐蝕 時(shí)間: 2025-3-23 22:28
Clinton Enoch,Christoph Krause,Jane Porathas an abundance of two abnormal structures, amyloid plaques (senile plaques) and neurofibrillary tangles. In addition, drebrin loss is another hallmark of AD brains, which is a common feature in the brain of both AD patients and AD mouse models. Strong evidence from human genetics and transgenic mou作者: Respond 時(shí)間: 2025-3-24 04:57 作者: FILTH 時(shí)間: 2025-3-24 08:33 作者: 誓言 時(shí)間: 2025-3-24 13:55 作者: 防止 時(shí)間: 2025-3-24 16:52 作者: 某人 時(shí)間: 2025-3-24 20:51 作者: 不能強(qiáng)迫我 時(shí)間: 2025-3-25 02:10
Book 2017including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in vario作者: 四牛在彎曲 時(shí)間: 2025-3-25 06:38
Remodeling of Actin Filaments by Drebrin A and Its Implications Drebrin A is highly enriched in dendritic spines, but its effects on actin morphology, dynamics, and interplay with other actin regulators are yet to be clarified. Here we review recent advances in understanding drebrin effects on actin morphology and dynamics.作者: NIL 時(shí)間: 2025-3-25 10:39
https://doi.org/10.1007/978-3-031-04386-4as tropomyosin, caldesmon, fascin, α-actinin, and cofilin. It also inhibits the activities of myosin-II and myosin-V. These results are discussed in terms of the possible roles of drebrin in the stability, dynamics, and organizations of actin structures in neuronal cells.作者: Amnesty 時(shí)間: 2025-3-25 14:26 作者: Aboveboard 時(shí)間: 2025-3-25 19:03
0065-2598 d by the discoverer of drebrin.Presents a multidisciplinary This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin fro作者: BILL 時(shí)間: 2025-3-25 23:53 作者: CLAP 時(shí)間: 2025-3-26 02:35
Biochemistry of Drebrin and Its Binding to Actin Filamentsas tropomyosin, caldesmon, fascin, α-actinin, and cofilin. It also inhibits the activities of myosin-II and myosin-V. These results are discussed in terms of the possible roles of drebrin in the stability, dynamics, and organizations of actin structures in neuronal cells.作者: neolith 時(shí)間: 2025-3-26 05:37 作者: anagen 時(shí)間: 2025-3-26 10:41
Book 2017xamines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a mar作者: 神秘 時(shí)間: 2025-3-26 13:49 作者: gene-therapy 時(shí)間: 2025-3-26 20:45
Definitions of Violence and Aggression Drebrin protein, which is well conserved in various vertebrate species, although mammalian drebrin has only two isoforms, namely, drebrin E and drebrin A, is different from chicken drebrin that has three isoforms. Drebrin belongs to an actin-depolymerizing factor homology (ADF-H) domain protein fam作者: Increment 時(shí)間: 2025-3-26 22:05
Markus Jelonek,Lukas Trost,Thomas Herrmannthe actin filament-binding protein drebrin and the microtubule-binding +TIP protein EB3. This pathway is regulated proximally by cyclin-dependent kinase 5 phosphorylation of drebrin but the upstream elements in the pathway have yet to be identified.作者: hypnotic 時(shí)間: 2025-3-27 02:53
Nikolaos Karagiannis,Debbie A. Mohammed regulated by a drebrin A-specific mechanism, is likely to affect the localization of drebrin E. In the adult brain, drebrin is mainly localized in dendritic spines, but in some nuclei, drebrin can be detected in neuronal somata as well as dendritic spines. The fact that the developmental changes in作者: JIBE 時(shí)間: 2025-3-27 07:30
Nikolaos Karagiannis,Debbie A. Mohammedic isoform, compensates for the genetic deletion of drebrin A. However, DAKO results in the loss of homeostatic plasticity of .-methyl-.-aspartate receptors (NMDARs). The NMDAR activation-dependent trafficking of the NR2A subunit-containing NMDARs from dendritic shafts into spine head cytoplasm is g作者: 不妥協(xié) 時(shí)間: 2025-3-27 11:42 作者: 隱語 時(shí)間: 2025-3-27 17:18
https://doi.org/10.1007/978-3-031-06592-7us via myosin II ATPase activation. The potentiated spines change to excited state because of the decrease in DF-actin and thus change their shape robustly. In LTP, the Ca. increase via NMDA receptors soon returns to the basal level, and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor 作者: Truculent 時(shí)間: 2025-3-27 19:26
Clinton Enoch,Christoph Krause,Jane Porathpresynaptic change in AD brains. In addition, dysregulation of glutamate receptor trafficking and the p21-activated kinase/LIM kinase pathway has been observed in AD brains. It is now believed that soluble Aβ oligomers, namely, Aβ-derived diffusible ligands (ADDLs), but not insoluble Aβ aggregation 作者: 注意 時(shí)間: 2025-3-27 22:51
Finland: Vocational Guidance in Finlandthology involved in neurodegeneration, Alzheimer’s disease (AD), other cognitive disorders, and aging..Bidirectional connexin channels are permeable to Ca. ions, IP3, ATP, and cAMP. Connexin hemichannels are important for paracrine regulation and can release and exchange energy with other cells usin作者: peak-flow 時(shí)間: 2025-3-28 02:43
https://doi.org/10.1007/978-3-031-06620-7 morphogenesis by cooperating with shank and activated Cdc42 small GTPase, suggesting a novel signaling pathway comprising Homer, drebrin, shank, and Cdc42 for spine morphogenesis. Drebrin sequesters spikar in the cytoplasm and stabilizes it in dendritic spines, leading to spine formation. Finally, 作者: magnate 時(shí)間: 2025-3-28 07:57 作者: 截?cái)?nbsp; 時(shí)間: 2025-3-28 13:11
0065-2598 the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a mar978-4-431-56817-9978-4-431-56550-5Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: investigate 時(shí)間: 2025-3-28 16:20 作者: cunning 時(shí)間: 2025-3-28 20:15
Molecular Cloning of Drebrin: Progress and Perspectives Drebrin protein, which is well conserved in various vertebrate species, although mammalian drebrin has only two isoforms, namely, drebrin E and drebrin A, is different from chicken drebrin that has three isoforms. Drebrin belongs to an actin-depolymerizing factor homology (ADF-H) domain protein fam作者: 反饋 時(shí)間: 2025-3-29 00:09 作者: 小蟲 時(shí)間: 2025-3-29 05:20
Localization of Drebrin: Light Microscopy Study regulated by a drebrin A-specific mechanism, is likely to affect the localization of drebrin E. In the adult brain, drebrin is mainly localized in dendritic spines, but in some nuclei, drebrin can be detected in neuronal somata as well as dendritic spines. The fact that the developmental changes in作者: 小淡水魚 時(shí)間: 2025-3-29 10:28 作者: FEAS 時(shí)間: 2025-3-29 13:58 作者: 無可非議 時(shí)間: 2025-3-29 15:41 作者: BAIT 時(shí)間: 2025-3-29 22:02
Drebrin in Alzheimer’s Diseasepresynaptic change in AD brains. In addition, dysregulation of glutamate receptor trafficking and the p21-activated kinase/LIM kinase pathway has been observed in AD brains. It is now believed that soluble Aβ oligomers, namely, Aβ-derived diffusible ligands (ADDLs), but not insoluble Aβ aggregation 作者: anthropologist 時(shí)間: 2025-3-30 00:39
Drebrins and Connexins: A Biomedical Perspectivethology involved in neurodegeneration, Alzheimer’s disease (AD), other cognitive disorders, and aging..Bidirectional connexin channels are permeable to Ca. ions, IP3, ATP, and cAMP. Connexin hemichannels are important for paracrine regulation and can release and exchange energy with other cells usin作者: frozen-shoulder 時(shí)間: 2025-3-30 05:25
Homer, Spikar, and Other Drebrin-Binding Proteins in the Brain morphogenesis by cooperating with shank and activated Cdc42 small GTPase, suggesting a novel signaling pathway comprising Homer, drebrin, shank, and Cdc42 for spine morphogenesis. Drebrin sequesters spikar in the cytoplasm and stabilizes it in dendritic spines, leading to spine formation. Finally, 作者: forestry 時(shí)間: 2025-3-30 11:26 作者: 全部 時(shí)間: 2025-3-30 12:25 作者: Fracture 時(shí)間: 2025-3-30 20:32 作者: –scent 時(shí)間: 2025-3-30 23:59
Biochemistry of Drebrin and Its Binding to Actin Filamentsin in vivo, we must understand its molecular properties. In this chapter, I will focus on the purification and characterization of drebrin in vitro. Drebrin binds to F-actin with a stoichiometry of 1:5~6 with a .. of 1~3 × 10. M and strongly inhibits the binding of other actin-binding proteins such 作者: bisphosphonate 時(shí)間: 2025-3-31 02:24
