標(biāo)題: Titlebook: DNA Damage and Repair; Amleto Castellani Book 1989 Springer Science+Business Media New York 1989 DNA.DNA repair.Nucleotide.biological.biol [打印本頁(yè)] 作者: 營(yíng)養(yǎng)品 時(shí)間: 2025-3-21 16:18
書目名稱DNA Damage and Repair影響因子(影響力)
書目名稱DNA Damage and Repair影響因子(影響力)學(xué)科排名
書目名稱DNA Damage and Repair網(wǎng)絡(luò)公開(kāi)度
書目名稱DNA Damage and Repair網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱DNA Damage and Repair被引頻次
書目名稱DNA Damage and Repair被引頻次學(xué)科排名
書目名稱DNA Damage and Repair年度引用
書目名稱DNA Damage and Repair年度引用學(xué)科排名
書目名稱DNA Damage and Repair讀者反饋
書目名稱DNA Damage and Repair讀者反饋學(xué)科排名
作者: burnish 時(shí)間: 2025-3-21 21:09 作者: incontinence 時(shí)間: 2025-3-22 03:54
Vance T. Holliday,Nan A. Rothschilde effects of radiation on nucleic acids. Hollaender died on December 6, 1986, shortly before his 88th birthday on December 19. His pioneering work led to the identification of nucleic acids as genetic material and to the existence of recovery following irradiation long before DNA was known to be imp作者: Trigger-Point 時(shí)間: 2025-3-22 06:10 作者: 分貝 時(shí)間: 2025-3-22 12:15
Della A. Scott-Ireton,David Gaimstertabolism. The excision repair of DNA damage in yeast is a complex process, controlled by a number of different genes in the so-called . epistasis group. Mutations at any of approximately 12 independent loci in this epistasis group cause cells to become abnormally sensitive to killing by ultraviolet 作者: justify 時(shí)間: 2025-3-22 13:17
Pedro Paulo A. Funari,Maria Ximena Senatore types of lesions that have to be recognized and removed, the enormous size of the mammalian genome and the complex chromatin structure, that should undergo reversible alterations for repair to take place. The finding of preferential repair of expressed genes as recently uncovered by Hanawalt and co作者: justify 時(shí)間: 2025-3-22 20:11
Agustin Azkarate,Sergio Escribano-Ruizraction of dimers from their total DNA, dimers are efficiently removed from the transcriptionally active dihydrofolate reductase (DHFR) gene and poorly removed from a sequence near the gene (Bohr et al., 1985). (ii) In mouse cells which also remove only a small fraction of dimers from their total DN作者: palliative-care 時(shí)間: 2025-3-22 23:56 作者: 偶像 時(shí)間: 2025-3-23 05:22
Patricia Fournier,Roberto Junco Sanchezorder trichothiodystrophy (TTD) (Stefanini et al. 1986). Cells from these patients showed a reduced capacity to repair the UV-induced DNA damage similar to that present in individuals affected by xeroderma pigmentosum (XP) and the complementation analysis demonstrated that the repair defect was the 作者: Abnormal 時(shí)間: 2025-3-23 06:55 作者: Hallmark 時(shí)間: 2025-3-23 13:29
The Latin American Studies Book Seriesin providing a marker of exposure to carcinogenic agents at an individual level and secondly in providing an insight on the biological relevance of these adducts to the process of carcinogenesis. In addition, these measurements, particularly if they reflect long-term exposure to carcinogens could re作者: AUGUR 時(shí)間: 2025-3-23 14:15
Laura Miotti,Lucía Magnin,Enrique Terranovaing nitrogen atoms of DNA bases, and on oxygen atoms of the phosphate groups to generate a variety of adducts. Two major pathways for the repair of alkylation damage have been identified. The removal of O.-methylguanine (O.-meG) adducts proceeds . the transfer of the alkyl group to a cysteine residu作者: 變白 時(shí)間: 2025-3-23 18:34 作者: 膽小懦夫 時(shí)間: 2025-3-23 22:25
Christine S. VanPool,Todd L. VanPooling species. A small group of all HD patients eventually develop acute nonlymphocytic leukemia (ANLL) some years after therapy (t-ANLL). We therefore initiated a study of the O. methylguanine DNA methyltransferase (MT) activity in normal controls and in patients with HD, ANLL . or t-ANLL. As part of作者: 公社 時(shí)間: 2025-3-24 03:52
Christine S. VanPool,Todd L. VanPools such as alkylpyrimidines. Some of them are repaired by alkyl DNA transferase while others are repaired by DNA glycosylases which generate as products the free alkylated base and an apurinic site (AP-site). This is a secondary lesion which is harmful to the cell and is actively repaired. Alkylation作者: 范圍廣 時(shí)間: 2025-3-24 09:40 作者: indigenous 時(shí)間: 2025-3-24 12:29
Alan A. D. Peatfield,Christine Morrists. Misreplication or misrepair of DNA adducts can lead to mutations, which in turn can act as the genetic precursors of cancer and other genetic diseases. A problem in contemporary cancer biology has been to discern the mechanisms by which DNA adducts lead to mutations. This problem is complicated 作者: 連詞 時(shí)間: 2025-3-24 18:09 作者: separate 時(shí)間: 2025-3-24 20:36
Ethnoarchaeological and Historical Methods,ing sunlight exposure, as well as the ability of cells in skin to repair or circumvent such damage. Although repair has been studied extensively in procaryotic and eucaryotic cells—including human cells in culture—there are important differences between repair by human skin cells in culture and huma作者: ENDOW 時(shí)間: 2025-3-25 00:39
Luise Albrecht,Marina D?ring-Williamsids constructed to permit both replication in bacteria and utilization of human host cell enzymes for expression or replication were used. Plasmids were treated with UV . permitting precise quantification of the extent of damage and selective reversal of dimers by photolyase. The treated plasmids we作者: CAMP 時(shí)間: 2025-3-25 04:59 作者: 暫時(shí)休息 時(shí)間: 2025-3-25 08:53 作者: dragon 時(shí)間: 2025-3-25 13:23
Vance T. Holliday,Nan A. Rothschilde effects of radiation on nucleic acids. Hollaender died on December 6, 1986, shortly before his 88th birthday on December 19. His pioneering work led to the identification of nucleic acids as genetic material and to the existence of recovery following irradiation long before DNA was known to be important or its structure was known.作者: Cardioversion 時(shí)間: 2025-3-25 19:53
Julie M. Schablitsky,Nigel J. Hetheringtonf the plethora of new compounds introduced into modern societies it is unlikely that there will have been sufficient time to evolve new enzymes to accommodate to such environmental changes. Therefore, this repair system is without stringent substrate specificity and, as a consequence, is sensitive to a broad spectrum of DNA damage.作者: Medicare 時(shí)間: 2025-3-25 22:39
https://doi.org/10.1007/978-1-4757-5016-4DNA; DNA repair; Nucleotide; biological; biology; cell; cells; energy; methylation; molecular biology; mutatio作者: cognizant 時(shí)間: 2025-3-26 02:58 作者: 說(shuō)不出 時(shí)間: 2025-3-26 07:58 作者: arrogant 時(shí)間: 2025-3-26 08:58
Repair of Secondary Lesions Arising in DNA after Treatment with Alkylating Agents, of the N7 of guanine labilizes i) the glycosidic bond yielding an AP-site and ii) the imidazole ring leading to the corresponding formamidopyrimidine, another secondary lesion. We review the biological implications of AP-sites and the formamidopyrimidine lesion which may form following alkylation of DNA.作者: hemophilia 時(shí)間: 2025-3-26 16:35 作者: 親密 時(shí)間: 2025-3-26 17:12
DNA Damage and Repair in Human Skin ,,n skin ..: quantitative differences in rates of repair (B. Sutherland et al., 1980; D’Ambrosio et al., 1981a), as well as qualitative differences, including the presence or absence of repair mechanisms (B. Sutherland et al., 1980; D’Ambrosio et al., 1981b).作者: 鍵琴 時(shí)間: 2025-3-26 21:34 作者: Anecdote 時(shí)間: 2025-3-27 04:01 作者: ENACT 時(shí)間: 2025-3-27 05:38
Isolation and Characterization of Genes Involved in Mammalian Excision Repair,red by damage in the template. The very recent discovery that the yeast repair gene RAD6 encodes a ubiquitin conjugating enzyme specific for histons 2A and 2B (Jentsch et al. 1987) and thought to be implicated in chromatin remodelling adds to the picture of tight interactions of repair events and chromatin structure and dynamics.作者: 高射炮 時(shí)間: 2025-3-27 11:02
Inducible Repair of Alkylated Bases in Mammalian Cells,ase and a DNA ligase ( 3 ). Other alkylated residues (e.g. O. -MeGua, O. -MeThy ) are repaired by a transferase which transfers the methyl group from the alkylated base to one of its own cystein residues ( 4–5 ).作者: FRAUD 時(shí)間: 2025-3-27 14:19 作者: –FER 時(shí)間: 2025-3-27 20:14
Karime Castillo,Patricia Fournierr there has been undue reliance on guesswork and extrapolation. Only recently, with the cloning of bacterial DNA repair genes and the synthesis of gene products in substantial quantities, has it been possible to work out the details of excision repair in . — and, as we know, the conventional model has proven wrong.作者: 辭職 時(shí)間: 2025-3-28 01:34 作者: Multiple 時(shí)間: 2025-3-28 02:40
The Latin American Studies Book Seriesese adducts to the process of carcinogenesis. In addition, these measurements, particularly if they reflect long-term exposure to carcinogens could result in an increase in the specificity and sensitivity of epidemiological studies.作者: 敵手 時(shí)間: 2025-3-28 06:26
Book 1989Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include carcino- genesis, photobiology, radiation biology, aging, enzymology, genetics, and molecular biology. These individual fields have th作者: Acetabulum 時(shí)間: 2025-3-28 11:49 作者: moribund 時(shí)間: 2025-3-28 17:32
Selective DNA Repair in the Transcribed Strands of Active Genes in Mammalian Cells,ii) In repair proficient human cells, dimers are removed more rapidly from the active DHFR gene than from bulk DNA or from the nontranscribed repetitive alpha sequences (Mellon et al., 1986). This work was recently reviewed by Smith (1987).作者: 墊子 時(shí)間: 2025-3-28 20:34 作者: Charade 時(shí)間: 2025-3-29 02:23 作者: 熒光 時(shí)間: 2025-3-29 06:28
DNA Alkylation Adducts in Human Cells Attributable to Exposure to Alkylating Agents,ese adducts to the process of carcinogenesis. In addition, these measurements, particularly if they reflect long-term exposure to carcinogens could result in an increase in the specificity and sensitivity of epidemiological studies.作者: 領(lǐng)先 時(shí)間: 2025-3-29 08:42 作者: 辯論 時(shí)間: 2025-3-29 14:37
Alan A. D. Peatfield,Christine Morrisby the fact that DNA damaging agents usually form not one, but many DNA lesions. As a result, it is a challenging task to assess the relative contributions of individual DNA adducts to the biological endpoint of mutation.作者: 創(chuàng)新 時(shí)間: 2025-3-29 19:02 作者: magnate 時(shí)間: 2025-3-29 22:14
Della A. Scott-Ireton,David Gaimsterboratories to clone the yeast genes involved in excision repair, with particular emphasis on the 5 genes which appear to be absolutely required for this process. The cloned genes can then be used to overexpress and purify specific Rad proteins, and hence to attempt to understand the biochemistry of 作者: Talkative 時(shí)間: 2025-3-30 02:41
https://doi.org/10.1007/978-981-32-9248-2 XP cells a transient correction of the defect was accomplished by micro-injection of cell-free extracts from wild-type sources. Some properties of the factor correcting XP cells from complementation group A are described..Micro-injection was also used to introduce the yeast photo-reactivating enzym作者: 龍卷風(fēng) 時(shí)間: 2025-3-30 08:01
Laura Miotti,Lucía Magnin,Enrique Terranovaployed are the same in prokaryotes and eukaryotes. For example, an alkyltransferase which transfers in a stoichiometric fashion the methyl group from the oxygen 6 of guanine to a cysteine thiol in the protein has been identified. along with a glycosylase activity capable of excising alkyl groups fro作者: 癡呆 時(shí)間: 2025-3-30 10:28
The Latin American Studies Book Seriestation and cell death following exposure to alkylating agents and contrast these with more recent data obtained from mammalian cells. (Since the biological effects of the alkylating agents which add bulky groups onto DNA can be alleviated by the UV damage repair system, we will concentrate on the ef作者: 衰弱的心 時(shí)間: 2025-3-30 13:53 作者: 枯燥 時(shí)間: 2025-3-30 18:36 作者: 無(wú)關(guān)緊要 時(shí)間: 2025-3-30 23:13 作者: 試驗(yàn) 時(shí)間: 2025-3-31 02:18 作者: 人類 時(shí)間: 2025-3-31 07:14 作者: Debate 時(shí)間: 2025-3-31 09:21 作者: Conscientious 時(shí)間: 2025-3-31 15:58 作者: 我不怕?tīng)奚?nbsp; 時(shí)間: 2025-3-31 18:41
The Response of Human Cells to , Methylation Damage, ± 0.63; six recently diagnosed ANLL patients had MT values of 7.8 ± 1.72, and 13 ANLL patients in remission had MT activities of 9.3 ± 2.3. The differences in MT value between normal subjects and HD patients, between t-ANLL and normal subjects, and between ANLL . and t-ANLL groups are significant. 作者: 谷物 時(shí)間: 2025-4-1 00:07 作者: Cosmopolitan 時(shí)間: 2025-4-1 02:49
DNA Repair and Mutagenesis Induced by Dimer and Non-Dimer Photoproducts Measured with Plasmid Vectocteria by the harvested plasmid was used to assess the plasmid survival and mutation frequency. DNA sequencing was performed on mutated plasmids recovered. Both cyclobutane dimer and non-dimer photoproducts were found to be poorly repaired and to be mutagenic in xeroderma pigmentosum cells.作者: indigenous 時(shí)間: 2025-4-1 06:42
Book 1989ngress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo- lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en- dogenous oxidative damages. The Congress and its Proceed作者: Highbrow 時(shí)間: 2025-4-1 12:58
of the Congress, encompass the field of DNA damage and repair. They cover biological systems ranging from mo- lecules to humans and deal with damages and repair after treatment of cells with various types of radiations, chemicals, and exogenous and en- dogenous oxidative damages. The Congress and its Proceed978-1-4757-5018-8978-1-4757-5016-4作者: 假設(shè) 時(shí)間: 2025-4-1 16:42
Twenty Five Years of DNA Repair,e effects of radiation on nucleic acids. Hollaender died on December 6, 1986, shortly before his 88th birthday on December 19. His pioneering work led to the identification of nucleic acids as genetic material and to the existence of recovery following irradiation long before DNA was known to be imp作者: opalescence 時(shí)間: 2025-4-1 21:42
