標(biāo)題: Titlebook: Cytoskeleton of the Nervous System; Ralph A. Nixon,Aidong Yuan Book 2011 Springer Science+Business Media, LLC 2011 [打印本頁(yè)] 作者: 怕跛行他有限 時(shí)間: 2025-3-21 18:58
書(shū)目名稱Cytoskeleton of the Nervous System影響因子(影響力)
書(shū)目名稱Cytoskeleton of the Nervous System影響因子(影響力)學(xué)科排名
書(shū)目名稱Cytoskeleton of the Nervous System網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱Cytoskeleton of the Nervous System網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱Cytoskeleton of the Nervous System被引頻次
書(shū)目名稱Cytoskeleton of the Nervous System被引頻次學(xué)科排名
書(shū)目名稱Cytoskeleton of the Nervous System年度引用
書(shū)目名稱Cytoskeleton of the Nervous System年度引用學(xué)科排名
書(shū)目名稱Cytoskeleton of the Nervous System讀者反饋
書(shū)目名稱Cytoskeleton of the Nervous System讀者反饋學(xué)科排名
作者: 有效 時(shí)間: 2025-3-22 00:07
Tauopathy and Brain Aging,ion, and NFTs can be thought of as a tombstone of neuronal dysfunction. Changes in tau may be involved in brain aging and may consequently lead to the formation of NFTs in the entorhinal cortex. This chapter introduces the mechanisms underlying neurodegeneration and brain aging that occur through ta作者: 承認(rèn) 時(shí)間: 2025-3-22 01:24 作者: 貞潔 時(shí)間: 2025-3-22 04:48
Structure of Neural Intermediate Filaments,ural IF can also be deduced, primarily from the pattern of cross-links induced between molecules. Using scanning transmission electron microscopy (STEM) and cryo-tomographic data, the neural IF are likely to have a four-protofibril structure containing 32 chains in section. Assembly occurs through a作者: Eviction 時(shí)間: 2025-3-22 12:34 作者: myriad 時(shí)間: 2025-3-22 13:57 作者: myriad 時(shí)間: 2025-3-22 19:32 作者: 通情達(dá)理 時(shí)間: 2025-3-22 23:32 作者: NAG 時(shí)間: 2025-3-23 04:13
Neurofilament Changes in Multiple Sclerosis,or protein within the axon. Mechanisms of axonal pathology in multiple sclerosis remain unknown, but inflammation in the acute disease phases is likely to cause significant damage. There is also evidence that axonal loss may continue even in the absence of inflammation. It has been postulated that a作者: 不理會(huì) 時(shí)間: 2025-3-23 09:25 作者: 蓋他為秘密 時(shí)間: 2025-3-23 12:19
Tropomyosins in Neuronal Morphogenesis and Development,ses controlling neuronal morphogenesis and development. Tm isoforms each have specific spatial distributions across tissue, cells and subcellular compartments. These distributions are temporally regulated, with expression levels and localisation of Tms changing throughout development. In brain, the 作者: 我正派 時(shí)間: 2025-3-23 15:33
2190-5215 e further development of unifying principles and stimulate new conceptual and technical approaches toward a better understanding of cytoskeleton functions in health and disease.978-1-4939-5142-0978-1-4419-6787-9Series ISSN 2190-5215 Series E-ISSN 2190-5223 作者: Flinch 時(shí)間: 2025-3-23 21:07
An?sthesie in Frage und Antwortstem. These aspects include the initial growth of the axon, the pathfinding mechanisms by which the axon locates the proper target, elimination of axonal connections to ensure the correct axon-to-target balance, and maturation of the axons to ensure proper transmission of signal, as well as the susc作者: Hiatal-Hernia 時(shí)間: 2025-3-23 23:56 作者: 好色 時(shí)間: 2025-3-24 05:10
überwachung w?hrend der Narkose promotes their elongation, and the tail region may contribute to the proper folding of the molecule. Isoforms of MAP4 are produced from the single MAP4 gene by alternative RNA splicing, thereby five isoforms, with a deletion in the Pro-rich region or the repeat region, are expressed. The expression作者: 扔掉掐死你 時(shí)間: 2025-3-24 06:51
https://doi.org/10.1007/978-3-662-05721-6ural IF can also be deduced, primarily from the pattern of cross-links induced between molecules. Using scanning transmission electron microscopy (STEM) and cryo-tomographic data, the neural IF are likely to have a four-protofibril structure containing 32 chains in section. Assembly occurs through a作者: 健談的人 時(shí)間: 2025-3-24 11:19
Intraoperative Flüssigkeitstherapiemponent of the major pathologic hallmarks of both familial and sporadic ALS – intracellular aggregates – and is found upregulated and abnormally spliced in areas of disease. Moreover, peripherin mutations have been associated with sporadic ALS cases, and transgenic overexpression of peripherin in mi作者: Mets552 時(shí)間: 2025-3-24 14:50 作者: NOMAD 時(shí)間: 2025-3-24 20:53
überwachung der Herz-Kreislauf-Funktiontangles (NFTs). NFTs are composed mainly of hyperphosphorylated Tau aggregates, the pathological hallmarks of neurodegenerative tauopathies and Alzheimer’s disease (AD). Cdk5, by phosphorylating neuronal cytoskeletal proteins, such as Tau and neurofilaments (NFs), plays a critical role in neurodegen作者: Truculent 時(shí)間: 2025-3-25 00:26 作者: enmesh 時(shí)間: 2025-3-25 05:41 作者: semiskilled 時(shí)間: 2025-3-25 10:47
Herz-Lungen-Maschine: An?sthesiemanagementne and to organelles, including the nucleus. Within the nucleus, IFs play a ubiquitously important role in structuring the nuclear envelope and help to regulate gene expression. Nuclear IF protein function is mediated through interactions with both large structural proteins and small regulatory prot作者: 挫敗 時(shí)間: 2025-3-25 15:20 作者: 無(wú)畏 時(shí)間: 2025-3-25 18:18 作者: ANTIC 時(shí)間: 2025-3-25 21:56
Georg Petroianu,Peter Michael Osswalde place at tyrosine residues, and the dephosphorylation of the modified residues by tau phosphatases. In addition, we will comment on the toxicity of phosphotau in disorders such as Alzheimer’s disease and the development of possible therapies to prevent tau phosphorylation.作者: debble 時(shí)間: 2025-3-26 03:22
R. Larsen,H. Sonntag,D. Kettler of a single intermediate filament and can now be considered to be a fourth subunit of NF in the adult CNS. Its role as a subunit of CNS NF explains the close relationship of α-internexin with the pathology of CNS diseases associated with NF accumulation.作者: albuminuria 時(shí)間: 2025-3-26 04:29
https://doi.org/10.1007/978-3-642-28291-1ng evidence for the involvement of neurofilaments in a number of neurodegenerative disorders such as amyotrophic lateral sclerosis, hereditary spastic paraplegia, Charcot–Marie–Tooth disease, and Alzheimer’s disease. Disrupted neurofilament transport is thought to be a common mechanism in some or all of these disorders.作者: 延期 時(shí)間: 2025-3-26 10:34
Intensivbehandlung nach Herzoperationenf neurofilament carboxy terminal phosphorylation in establishing axonal diameter. In this review, the contribution of each neurofilament gene-targeted mouse to our current understanding of the role of neurofilaments and neurofilament phosphorylation in radial axonal growth is discussed.作者: 有危險(xiǎn) 時(shí)間: 2025-3-26 15:11
https://doi.org/10.1007/978-3-662-52987-4l argue that coordinated activity of these molecular events determines the speed and direction of axon growth, with particular emphasis on how Ca. signals control the driving machinery for growth cone navigation.作者: GRAZE 時(shí)間: 2025-3-26 18:09
Tau Phosphorylation,e place at tyrosine residues, and the dephosphorylation of the modified residues by tau phosphatases. In addition, we will comment on the toxicity of phosphotau in disorders such as Alzheimer’s disease and the development of possible therapies to prevent tau phosphorylation.作者: ostracize 時(shí)間: 2025-3-26 22:57 作者: Obstruction 時(shí)間: 2025-3-27 05:07
Neurofilament Transport,ng evidence for the involvement of neurofilaments in a number of neurodegenerative disorders such as amyotrophic lateral sclerosis, hereditary spastic paraplegia, Charcot–Marie–Tooth disease, and Alzheimer’s disease. Disrupted neurofilament transport is thought to be a common mechanism in some or all of these disorders.作者: 凝結(jié)劑 時(shí)間: 2025-3-27 07:08 作者: biopsy 時(shí)間: 2025-3-27 10:19
The Driving Machinery for Growth Cone Navigation,l argue that coordinated activity of these molecular events determines the speed and direction of axon growth, with particular emphasis on how Ca. signals control the driving machinery for growth cone navigation.作者: Estrogen 時(shí)間: 2025-3-27 17:09
2190-5215 ctin and its binding proteins, and glial fibrillary acidic pThis monograph begins with a general description of the cytoskeleton in axonal development and pathology and then moves to more detailed descriptions of particular components, including microtubules and associated proteins, neurofilaments a作者: BUMP 時(shí)間: 2025-3-27 21:51 作者: ONYM 時(shí)間: 2025-3-27 22:52
Technische Vorbereitungen für die Narkosezheimer’s disease and in several neurologic disorders – the so-called tauopathies. In animal models, overexpression of mutated tau proteins is often used to induce a tau pathology leading to motor and/or cognitive dysfunction. Tau pathology is certainly a good therapeutic target, but untangling tau remains a major therapeutic challenge.作者: 胖人手藝好 時(shí)間: 2025-3-28 04:32 作者: AV-node 時(shí)間: 2025-3-28 08:09 作者: 富足女人 時(shí)間: 2025-3-28 12:57 作者: corpus-callosum 時(shí)間: 2025-3-28 14:46 作者: FER 時(shí)間: 2025-3-28 19:01 作者: Vital-Signs 時(shí)間: 2025-3-29 00:04
Ralph A. Nixon,Aidong YuanDescribes cytoskeleton in axonal development and pathology, microtubules and associated proteins, neurofilaments and interacting proteins, actin and its binding proteins, and glial fibrillary acidic p作者: 個(gè)人長(zhǎng)篇演說(shuō) 時(shí)間: 2025-3-29 05:52
Advances in Neurobiologyhttp://image.papertrans.cn/d/image/242687.jpg作者: 曲解 時(shí)間: 2025-3-29 10:47 作者: arrogant 時(shí)間: 2025-3-29 14:07 作者: Precursor 時(shí)間: 2025-3-29 19:19 作者: impale 時(shí)間: 2025-3-29 21:21 作者: growth-factor 時(shí)間: 2025-3-30 00:02
Technische Vorbereitungen für die Narkoseon of this degenerating process along neuronal circuitry. Tau proteins belong to the family of microtubule-associated proteins. They are essential for the assembly of tubulin dimers into microtubules and their parallel-ordered organization. Tau is strongly expressed in neurons, localized in the axon作者: exhilaration 時(shí)間: 2025-3-30 04:56 作者: Palpable 時(shí)間: 2025-3-30 10:56
überwachung w?hrend der Narkosebulin polymerization and stabilizes polymerized-microtubules as do neural MAPs. Because MAP2, MAP4, and tau are structurally similar, the three MAPs are considered to constitute a superfamily. The architecture of the superfamily proteins consists of an amino-terminal projection domain and a carboxyl作者: 場(chǎng)所 時(shí)間: 2025-3-30 14:44
https://doi.org/10.1007/978-3-662-05721-6pecific and fully functional IF. It has been established that the IF molecule is a dimer and that its two constituent chains lie parallel to each other and in axial register. The molecule has a tripartite structure with a central, α-helical, coiled-coil–rich region (the rod domain) separating the he作者: 拖網(wǎng) 時(shí)間: 2025-3-30 18:41 作者: Nmda-Receptor 時(shí)間: 2025-3-30 22:51 作者: 鞏固 時(shí)間: 2025-3-31 02:49
https://doi.org/10.1007/978-3-662-50444-4mately 10?nm diameter. Among intermediate filaments, NFs have unique chemical and structural properties. They are composed of three distinctly different proteins called . (NF-L, NF-M, and NF-H) and are constituted morphologically of two distinct domains in vivo: core filaments and cross-bridges late作者: 我邪惡 時(shí)間: 2025-3-31 08:11
https://doi.org/10.1007/978-3-642-28291-1n the soma and transported into axonal and dendritic processes. Neurofilaments are transported by the process of slow axonal transport, which arises from fast transport interrupted by extended pauses. Some of the mechanisms regulating neurofilament assembly and transport have been identified. It is 作者: instulate 時(shí)間: 2025-3-31 11:38
überwachung der Herz-Kreislauf-Funktione last 15 years, the gene targeting technique has been widely used to investigate the role of NF proteins in neuronal function. Gene knockout studies have demonstrated that NFs are crucial to expand the caliber of myelinated axons and consequently to increase their conduction velocity. However, the 作者: 沐浴 時(shí)間: 2025-3-31 14:50
Intensivbehandlung nach Herzoperationenlong the axon. Prior to the development of neurofilament gene-targeted mice, it was thought that radial growth was mediated by myelin-dependent phosphorylation of neurofilament heavy and neurofilament medium within the axon. The systematic analysis of gene-targeted mice has furthered our understandi作者: Traumatic-Grief 時(shí)間: 2025-3-31 20:38
überwachung der Herz-Kreislauf-Funktionpendent kinase 5 (Cdk5), Glycogen synthase kinase 3β (GSK3β) and MAPKs have been implicated in their direct involvement in neuronal cytoskeletal protein phosphorylation. Cdk5 and GSK3β have been identified as prime candidates for pathogenesis. Cdk5 is a proline-directed serine/threonine protein kina作者: 天然熱噴泉 時(shí)間: 2025-4-1 01:14 作者: 譏笑 時(shí)間: 2025-4-1 05:11 作者: 蜿蜒而流 時(shí)間: 2025-4-1 06:41
Herz-Lungen-Maschine: An?sthesiemanagementd the central and peripheral nervous systems. In general, their properties suggest that IFs play important roles in maintaining the mechanical stability of tissues undergoing severe mechanical stress. However, the lack of cytoplasmic IFs in the nervous system of some animals and the lack of phenotyp作者: 隱語(yǔ) 時(shí)間: 2025-4-1 13:58
überwachung der Herz-Kreislauf-Funktion18.2 a detailed description of the expression patterns of these isoforms throughout development in neurons and the brain, Section?18.3 summarises the actin binding proteins (ABPs) which are localised in neurons and which interact with these Tm isoforms, Section?18.4 discusses the growth cone, and ho作者: 密碼 時(shí)間: 2025-4-1 14:18
https://doi.org/10.1007/978-3-662-52987-4ssociated motors generate traction force that is transmitted to the surrounding environment via cell adhesion molecules. The force transmission can be spatiotemporally controlled by a molecular clutch that mediates mechanical coupling of cell adhesion molecules and the actin cytoskeleton. Furthermor作者: agenda 時(shí)間: 2025-4-1 19:19
978-1-4939-5142-0Springer Science+Business Media, LLC 2011
