標題: Titlebook: Current and Future Immunosuppressive Therapies Following Transplantation; Mohamed H. Sayegh,Giuseppe Remuzzi Book 2001 Springer Science+Bu [打印本頁] 作者: 教條 時間: 2025-3-21 19:01
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation影響因子(影響力)
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation影響因子(影響力)學科排名
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書目名稱Current and Future Immunosuppressive Therapies Following Transplantation網(wǎng)絡公開度學科排名
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation被引頻次
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation被引頻次學科排名
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation年度引用
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation年度引用學科排名
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation讀者反饋
書目名稱Current and Future Immunosuppressive Therapies Following Transplantation讀者反饋學科排名
作者: MEET 時間: 2025-3-21 23:03 作者: 懲罰 時間: 2025-3-22 02:11
12 x 12 Schlüsselkonzepte zur Mathematikore selective and specific agents has become, in the past decade, one of the priorities for transplant medicine. Some of these compounds are now entering routine clinical practice: among them are tacrolimus, mycophenolate mofetil (MMF) and sirolimus.作者: 休息 時間: 2025-3-22 08:15
50 Schlüsselideen Wirtschaftswissenschaftsm of action of tacrolimus, and then go on to summarize its use as both primary immunosuppressive agent and as rescue agent in adult and pediatric sold organ transplantation (emphasizing the most recent multi-center and selected single center trial data), its dosage, its use in combination with othe作者: 下垂 時間: 2025-3-22 12:37
https://doi.org/10.1007/978-3-8274-2900-1he requirements for immunotherapy. For example, the risk of acute rejection is greater in children, African-Americans and in recipients who are sensitized to HLA [3]. Taken together, these observations have provided the rationale for the development of induction immunosuppressive strategies that min作者: infinite 時間: 2025-3-22 14:26
https://doi.org/10.1007/978-3-8274-2900-1T3, a murine anti-CD. monoclonal antibody, was introduced in 1986. The mechanism of action of OKT3 consists of T cell depletion and CD. modulation. While the polyclonal agents and OKT3 induce effective immunosuppression, they are also associated with opportunistic infections and post transplant lymp作者: infinite 時間: 2025-3-22 19:34
https://doi.org/10.1007/978-3-8274-2900-1ation of these molecules and activation events. Furthermore, biological processes have evolved to facilitate these processes in as much as the interaction between cognate antigen and the T cell receptor is a process that facilitates the expression of high affinity adhesion molecules; and disruption 作者: 萬花筒 時間: 2025-3-22 22:40 作者: Endemic 時間: 2025-3-23 05:11 作者: sleep-spindles 時間: 2025-3-23 06:19
Pharmacologic Monitoring of Immunosuppressive Drugsore selective and specific agents has become, in the past decade, one of the priorities for transplant medicine. Some of these compounds are now entering routine clinical practice: among them are tacrolimus, mycophenolate mofetil (MMF) and sirolimus.作者: Gourmet 時間: 2025-3-23 10:34 作者: EXPEL 時間: 2025-3-23 17:04 作者: 王得到 時間: 2025-3-23 20:40
Monoclonal Antibody Targeting of the Il-2R ComplexT3, a murine anti-CD. monoclonal antibody, was introduced in 1986. The mechanism of action of OKT3 consists of T cell depletion and CD. modulation. While the polyclonal agents and OKT3 induce effective immunosuppression, they are also associated with opportunistic infections and post transplant lymp作者: Instantaneous 時間: 2025-3-24 00:57 作者: 占線 時間: 2025-3-24 04:30 作者: 沙發(fā) 時間: 2025-3-24 09:03
Immunomodulatory Function of MHC Peptidesugh many diverse mechanisms including inhibition of cell cycle progresssion, altered signal transduction and the induction of apoptosis. The potential, therefore, exists that peptides, or compounds derived from them, may represent an exciting new form of immunotherapy.作者: Thrombolysis 時間: 2025-3-24 14:23 作者: 定點 時間: 2025-3-24 16:24 作者: CHASE 時間: 2025-3-24 19:39 作者: 尖酸一點 時間: 2025-3-25 01:27 作者: 禁令 時間: 2025-3-25 04:42
Quadratzahlen und Quadratwurzeln,anquisher of obstacles, was created by Shiva, who xenografted the head of an elephant onto the body of the child [1]. In the Iliad, Homer describes the Chimaera, a fabulous creature that is part lion, part goat, and part serpent. The writings of Lieh Tzu in 300 B.C. report the use of a “wonderful dr作者: 保守 時間: 2025-3-25 08:59
https://doi.org/10.1007/978-3-8274-2298-9e. The experimental design most appropriate for the comparison of therapeutic intervention is the randomized controlled clinical trial. These trials are designed to assess the efficacy of treatment in quantitative terms which are frequency of defined events (primary end-points) and time course of di作者: Grandstand 時間: 2025-3-25 15:00 作者: Eeg332 時間: 2025-3-25 18:01
https://doi.org/10.1007/978-3-8274-2379-5nt used for human kidney transplant recipients in the late 1950s. However, in 1951, Billingham et al demonstrated that steroids prevented rejection and prolonged the survival of skin grafts in rabbits [1]. The effectiveness of large doses of corticosteroids in suppressing and reversing human renal a作者: 擁護者 時間: 2025-3-25 20:31
https://doi.org/10.1007/978-3-8274-2379-5metabolites to be used in chronic immunosuppression protocols having been shown to be effective in renal transplantation in dogs [1] and subsequently in humans [2]. Azathioprine remained a mainstay of chronic immunosuppression protocols until the mid-1990s when it was shown in double-blind randomize作者: mercenary 時間: 2025-3-26 03:41 作者: hieroglyphic 時間: 2025-3-26 05:43 作者: 現(xiàn)暈光 時間: 2025-3-26 09:47 作者: Mercurial 時間: 2025-3-26 14:22 作者: 不斷的變動 時間: 2025-3-26 20:07 作者: Encoding 時間: 2025-3-26 22:36 作者: NOT 時間: 2025-3-27 03:33
https://doi.org/10.1007/978-3-8274-2900-1 rejection [1–3]. The initial rationale for these studies was the capacity of OKT3 to stain all mature peripheral T cells and to completely abolish both T cell proliferation and the generation of cytotoxic T cell effectors in . mixed lymphocyte cultures [4]. Interestingly enough, this occurred in 19作者: 微塵 時間: 2025-3-27 07:44
https://doi.org/10.1007/978-3-8274-2900-1block T cell responses at the time of antigen presentation following allograft transplantation in an effort to reorient the host immune response toward accommodation rather than rejection. The first biologic agents that were used for induction were polyclonal antilymphocyte preparations obtained fro作者: Hamper 時間: 2025-3-27 11:21
https://doi.org/10.1007/978-3-8274-2900-1n. Over the past few decades, multiple investigators have defined series of families of adhesion molecules that provide for intimate cell-cell contact and facilitate interactions among another series of activation molecules. To this end, the process of adhesion is intimately associated with activati作者: 四溢 時間: 2025-3-27 15:54 作者: 爆米花 時間: 2025-3-27 18:02 作者: 為寵愛 時間: 2025-3-27 23:38 作者: 咆哮 時間: 2025-3-28 04:37 作者: 統(tǒng)治人類 時間: 2025-3-28 09:53 作者: 良心 時間: 2025-3-28 14:08
https://doi.org/10.1007/978-94-010-1005-4T cell; clinical trial; gene therapy; immunology; immunosuppression; kidney; organ; organ transplantation; t作者: 使高興 時間: 2025-3-28 15:49
978-94-010-3876-8Springer Science+Business Media New York 2001作者: FACT 時間: 2025-3-28 22:24 作者: AWRY 時間: 2025-3-29 00:55
https://doi.org/10.1007/978-3-8274-2379-5llograft rejection was first reported in the early 1960s [2],[3]. Thereafter, combination of azathioprine and steroids became the conventional maintenance immunosuppression regimen in organ transplantation and remained so for almost two decades.作者: 浮雕 時間: 2025-3-29 04:18
https://doi.org/10.1007/978-3-8274-2379-5d trials that mycophenolate mofetil (MMF) had better efficacy for the prevention of acute rejection following renal transplantation [3–5]. Although MMF has replaced azathioprine in chronic immunosuppression protocols, many centers still use azathioprine, particularly in low-risk patients.作者: 壓倒性勝利 時間: 2025-3-29 10:05 作者: 同音 時間: 2025-3-29 11:50 作者: frenzy 時間: 2025-3-29 16:14
Entschlüsselung des genetischen Codesiver, pancreas, and lung transplants are possible. Cyclosporine is a cyclic polypeptide consisting of 11 aminoacids and molecular weight of approximately 1200 (C. H. N. 0.) The cyclic structure is necessary for its immunosuppressive effect.作者: capsule 時間: 2025-3-29 20:09
https://doi.org/10.1007/978-3-8274-2900-1till manufacture their own preparations for use in their own programs. It is conservatively estimated that between 300,000 and 400,00 transplant patients have been treated with various forms of ALG or ATG. Thus polyclonal antilymphocyte preparations have had and continue to have a significant impact in clinical transplantation.作者: 妨礙 時間: 2025-3-30 03:52 作者: 搏斗 時間: 2025-3-30 05:10
Ponyclonal Antilymphocyte Antibodiestill manufacture their own preparations for use in their own programs. It is conservatively estimated that between 300,000 and 400,00 transplant patients have been treated with various forms of ALG or ATG. Thus polyclonal antilymphocyte preparations have had and continue to have a significant impact in clinical transplantation.作者: Colonnade 時間: 2025-3-30 08:58 作者: Contend 時間: 2025-3-30 13:51 作者: febrile 時間: 2025-3-30 18:31
Clinical Trials in Transplant Immunosuppression: What Have We Learned?sease. Randomization minimizes selection bias and prevents bias in the comparison between study groups due to regression toward the mean. However, there is no guarantee that bias is entirely eliminated even in a prospective study with double blinding.作者: 不能強迫我 時間: 2025-3-30 23:31
Use of Corticosteroids in Kidney Transplantionllograft rejection was first reported in the early 1960s [2],[3]. Thereafter, combination of azathioprine and steroids became the conventional maintenance immunosuppression regimen in organ transplantation and remained so for almost two decades.作者: Ledger 時間: 2025-3-31 02:16
Mycophenolate Mofetil and Azathioprined trials that mycophenolate mofetil (MMF) had better efficacy for the prevention of acute rejection following renal transplantation [3–5]. Although MMF has replaced azathioprine in chronic immunosuppression protocols, many centers still use azathioprine, particularly in low-risk patients.作者: HACK 時間: 2025-3-31 06:18
Monoclonal Antibody Targeting of the T Cell Receptor Complex81, few years before it could be firmly established that the specific molecular target of OKT3 was one of the polypeptide chains included within the major T cell recognition element namely, the T cell antigen receptor (TCR)/CD3 complex.作者: Diastole 時間: 2025-3-31 12:09
Book 2001 the basic science mechanisms andclinical applicability of these strategies. The uniqueness of thisbook is the inclusion of up-to-date information on the basicmechanisms of actions of the immunosuppressive drugs as well as asummary of the clinical trials data and the potential use of thesedrugs in c作者: 聲音刺耳 時間: 2025-3-31 13:59 作者: inhumane 時間: 2025-3-31 20:33
Clinical Trials in Transplant Immunosuppression: What Have We Learned?e. The experimental design most appropriate for the comparison of therapeutic intervention is the randomized controlled clinical trial. These trials are designed to assess the efficacy of treatment in quantitative terms which are frequency of defined events (primary end-points) and time course of di