標題: Titlebook: Computational Methods in Systems Biology; 15th International C Jér?me Feret,Heinz Koeppl Conference proceedings 2017 Springer International [打印本頁] 作者: BULB 時間: 2025-3-21 17:48
書目名稱Computational Methods in Systems Biology影響因子(影響力)
書目名稱Computational Methods in Systems Biology影響因子(影響力)學科排名
書目名稱Computational Methods in Systems Biology網絡公開度
書目名稱Computational Methods in Systems Biology網絡公開度學科排名
書目名稱Computational Methods in Systems Biology被引頻次
書目名稱Computational Methods in Systems Biology被引頻次學科排名
書目名稱Computational Methods in Systems Biology年度引用
書目名稱Computational Methods in Systems Biology年度引用學科排名
書目名稱Computational Methods in Systems Biology讀者反饋
書目名稱Computational Methods in Systems Biology讀者反饋學科排名
作者: 不吉祥的女人 時間: 2025-3-21 23:16
https://doi.org/10.1007/978-3-031-43666-6programming. The framework is based on Boolean control networks where the topological network actions are modelled by control parameters. We present a new algorithm using abductive reasoning principles inferring the minimal causal topological actions leading to an expected behavior at stable state. 作者: Dawdle 時間: 2025-3-22 00:54 作者: FRAUD 時間: 2025-3-22 04:59 作者: 血統(tǒng) 時間: 2025-3-22 09:04
Jenny B?ckstrand,Andréas Malmstedts which can serve as markers of presence or absence for implementing program control instructions in the cell and imperative programs. Then we start comparing our compiler-generated circuits to the natural circuit of the MAPK signaling network, which plays the role of an analog-digital converter in 作者: Free-Radical 時間: 2025-3-22 12:56 作者: Free-Radical 時間: 2025-3-22 17:36 作者: 一再煩擾 時間: 2025-3-23 00:40
Defining Solution Spaces for Customizationsvaluation of our robust AP design, demonstrating the potential of this approach, without explicit meal announcements, to support high carbohydrate disturbances and to regulate glucose levels in large clusters of virtual patients learned from population-wide survey data.作者: Annotate 時間: 2025-3-23 04:00
Lean Leadership in Production Ramp-Upations of signaling pathways when cells are treated with drugs targeting specific activities or protein states. We also explore ideas for conjecturing targets of unknown drugs. We illustrate the methods on phosphoproteomics data (RPPA) from SKMEL133 melanoma cancer cells treated with different drugs作者: 使殘廢 時間: 2025-3-23 07:49 作者: 能量守恒 時間: 2025-3-23 12:28 作者: 刻苦讀書 時間: 2025-3-23 17:26 作者: larder 時間: 2025-3-23 19:42
Probably Approximately Correct Learning of Regulatory Networks from Time-Series Datamonotone DNF formulae and learned actively with both activation samples and oracle calls. We consider Boolean traces and Boolean abstractions of stochastic simulation traces, and study the space-time tradeoff there is between the diversity of initial states and the length of the time horizon, and it作者: LARK 時間: 2025-3-23 23:57 作者: FAWN 時間: 2025-3-24 05:25 作者: 膽小懦夫 時間: 2025-3-24 06:40 作者: Terrace 時間: 2025-3-24 12:18
Detecting Toxicity Pathways with a Formal Framework Based on Equilibrium Changesribe qualitative equilibrium changes and the chaining of rules is controlled by constraints expressed in extended temporal logic. This higher abstraction level fosters the detection of toxicity pathways, as we will show through an example of endocrine disruption of the thyroid hormone system.作者: 龍蝦 時間: 2025-3-24 18:04
Data-Driven Robust Control for Type 1 Diabetes Under Meal and Exercise Uncertaintiesvaluation of our robust AP design, demonstrating the potential of this approach, without explicit meal announcements, to support high carbohydrate disturbances and to regulate glucose levels in large clusters of virtual patients learned from population-wide survey data.作者: GNAT 時間: 2025-3-24 22:38 作者: 商議 時間: 2025-3-25 01:26
Automated Property Synthesis of ODEs Based Bio-pathways Modelsbe unknown parameters. We classify a given model’s behavior as corresponding to one of these templates using a convolutional neural network. We then synthesize a concrete property from this template by estimating its parameters via a standard search procedure combined with statistical model checking作者: 長處 時間: 2025-3-25 06:31 作者: 刪減 時間: 2025-3-25 08:29
0302-9743 -performance computational?systems biology and parallel implementations; model inference from experimental?data; model integration from biological databases; multi-scale modeling and?analysis methods; and computational approaches for synthetic biology.978-3-319-67470-4978-3-319-67471-1Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: gonioscopy 時間: 2025-3-25 14:28 作者: 思考 時間: 2025-3-25 16:53 作者: TIA742 時間: 2025-3-25 22:57
https://doi.org/10.1007/978-3-319-99704-9bility results of the modeled system, e.g., concerning trap or no-return sets, can then be derived without enumerating and analyzing all models in the set. The close correspondence of the graph to similar objects for differential equations furthermore opens up ways to relate Boolean and continuous models.作者: Munificent 時間: 2025-3-26 04:10 作者: SOBER 時間: 2025-3-26 05:38
Temporal Reprogramming of Boolean Networksations) or only temporary, to achieve the existential or inevitable reachability of an arbitrary state of the system. We apply a prototype implementation on small models from the literature and show that we are able to derive temporal perturbations to achieve trans-differentiation.作者: TOM 時間: 2025-3-26 09:57 作者: 初次登臺 時間: 2025-3-26 15:54
Detecting Attractors in Biological Models with Uncertain Parametersconnected components (tSCCs). In this paper, we introduce a novel method for detecting tSCCs in parametrised graphs. The method is supplied with a parallel algorithm and evaluated on discrete abstractions of several non-linear biological models.作者: Engaged 時間: 2025-3-26 19:28
Bio-Curation for Cellular Signalling: The KAMI Projectation problem. The current state of the ongoing development of the . (.nowledge .ggregator & .odel .nstantiator) bio-curation tool, based on this approach, is detailed along with our plans for future development.作者: 有斑點 時間: 2025-3-26 22:55
https://doi.org/10.1007/978-3-642-16358-6connected components (tSCCs). In this paper, we introduce a novel method for detecting tSCCs in parametrised graphs. The method is supplied with a parallel algorithm and evaluated on discrete abstractions of several non-linear biological models.作者: grandiose 時間: 2025-3-27 01:46 作者: 發(fā)微光 時間: 2025-3-27 05:26 作者: Salivary-Gland 時間: 2025-3-27 11:00
Conference proceedings 2017stadt, Germany, in September 2017. The 15 full papers, 4 tool papersand 4 posters presented together with 1 invited talk were carefully reviewed and selected from 41 ?regular paper submissions. Topics of interest include formalisms for modeling ?biological processes; models?and their biological appl作者: Lethargic 時間: 2025-3-27 14:14
Melissa Marques-McEwan,Umit Sezer Bititciighborhood dependencies. We perform numerical analysis of the HMMs applied to bisulfite sequencing measurements and accurately predict wild-type data. In addition, we find evidence that the enzymes’ activities depend on the left 5’ neighborhood but not on the right 3’ neighborhood.作者: 炸壞 時間: 2025-3-27 18:16 作者: 密切關系 時間: 2025-3-28 00:55
https://doi.org/10.1007/978-3-319-67471-1formal methods; live and medical sciences; model checking; simulation and modeling uncertainty; quantifi作者: 展覽 時間: 2025-3-28 04:44 作者: 追逐 時間: 2025-3-28 07:53 作者: 冷漠 時間: 2025-3-28 10:47 作者: Obituary 時間: 2025-3-28 17:58
Computational Methods in Systems Biology978-3-319-67471-1Series ISSN 0302-9743 Series E-ISSN 1611-3349 作者: 匯總 時間: 2025-3-28 19:22
Xinghang Dai,Nada Matta,Guillaume Ducellierresented, based on rewriting in hierarchies of graphs, together with a specific instantiation of the methodology that addresses our particular bio-curation problem. The current state of the ongoing development of the . (.nowledge .ggregator & .odel .nstantiator) bio-curation tool, based on this appr作者: Harridan 時間: 2025-3-29 01:10 作者: GUILT 時間: 2025-3-29 05:43
https://doi.org/10.1007/978-3-642-16358-6ermine these attractors. Biological systems are usually described by highly parametrised dynamical models that can be represented as parametrised graphs typically constructed as discrete abstractions of continuous-time models. In such models, attractors are observed in the form of terminal strongly 作者: 大約冬季 時間: 2025-3-29 08:03 作者: Conserve 時間: 2025-3-29 13:45
https://doi.org/10.1007/978-3-031-43666-6ver, despite the spectacular progress of machine learning techniques in data analytics, classification, clustering and prediction making, learning dynamical models from data time-series is still challenging. In this paper we investigate the use of the Probably Approximately Correct (PAC) learning fr作者: FLUSH 時間: 2025-3-29 16:56 作者: Brochure 時間: 2025-3-29 19:44 作者: 可用 時間: 2025-3-30 03:18 作者: 帶子 時間: 2025-3-30 06:25
Felix Schulze,Patrick Dallasegaaccessible. However, reproducing published results, either experimental data or observations is often not viable. In this work, we propose a framework to overcome some of the issues of reproducing previous research, and to ensure re-usability of published information. We present here a framework tha作者: 易于交談 時間: 2025-3-30 12:03
Melissa Marques-McEwan,Umit Sezer Bititciitable changes in gene expression not encoded by the DNA sequence. The underlying mechanisms controlling DNA methylation are only partly understood and recently different mechanistic models of enzyme activities responsible for DNA methylation have been proposed. Here we extend existing Hidden Markov作者: 史前 時間: 2025-3-30 14:59
Jarle Nyberg,Sverre S?rbye Larsenurb. Most of computational methods focus on finding mutations to apply to the initial state in order to control which attractor the cell will reach. However, it has been shown, and is proved in this article, that waiting between the perturbations and using the transient dynamics of the system allow 作者: CURT 時間: 2025-3-30 19:08 作者: Clumsy 時間: 2025-3-30 20:43 作者: CBC471 時間: 2025-3-31 03:08
https://doi.org/10.1007/978-3-319-99704-9zing sets of models consistent with the available information. In this setting, methods not depending on consideration of every single model in the set are necessary for efficient analysis. Drawing from ideas developed in qualitative differential equation theory, we present an approach to analyze se作者: Subjugate 時間: 2025-3-31 06:18
Lean Leadership in Production Ramp-Upk. Each specific model system builds on a knowledge base of rules formalizing local process steps such as post translational modification. The Pathway Logic Assistant (PLA) is a collection of visualization and reasoning tools that allow users to derive specific executable models by specifying of an
