標(biāo)題: Titlebook: Computational Design of Membrane Proteins; Irina S. Moreira,Miguel Machuqueiro,Joana Mour?o Book 2021 Springer Science+Business Media, LLC [打印本頁(yè)] 作者: 動(dòng)詞 時(shí)間: 2025-3-21 19:45
書目名稱Computational Design of Membrane Proteins影響因子(影響力)
書目名稱Computational Design of Membrane Proteins影響因子(影響力)學(xué)科排名
書目名稱Computational Design of Membrane Proteins網(wǎng)絡(luò)公開度
書目名稱Computational Design of Membrane Proteins網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Computational Design of Membrane Proteins被引頻次
書目名稱Computational Design of Membrane Proteins被引頻次學(xué)科排名
書目名稱Computational Design of Membrane Proteins年度引用
書目名稱Computational Design of Membrane Proteins年度引用學(xué)科排名
書目名稱Computational Design of Membrane Proteins讀者反饋
書目名稱Computational Design of Membrane Proteins讀者反饋學(xué)科排名
作者: 榮幸 時(shí)間: 2025-3-22 00:02 作者: 整體 時(shí)間: 2025-3-22 00:57 作者: Lignans 時(shí)間: 2025-3-22 04:50
Engineering of Biological Pathways: Complex Formation and Signal Transduction systems—the artificial rewiring of biological pathways. Here we describe the three-dimensional structure-based design of “rewiring” mutations using the FoldX force field. Specifically, we provide the protocol for the design and selection of interface mutations in three Ras-effector complex structur作者: ANIM 時(shí)間: 2025-3-22 11:13
Homology Modeling of Class A G-Protein-Coupled Receptors in the Age of the Structure Boome target of about 30% of presently available pharmaceutical drugs. The recent boom in GPCR structures led to the structural resolution of 57 unique receptors in different states (39 receptors in inactive state only, 2 receptors in active state only and 16 receptors in different activation states). I作者: 密切關(guān)系 時(shí)間: 2025-3-22 16:52
Interface Prediction for GPCR Oligomerization Between Transmembrane Helicescourse of molecular evolution. The mechanisms of GPCR interactions and the reason why GPCRs interact between themselves have remained elusive. Accurate interface prediction is useful to generate guidelines for mutation and inhibition experiments and would accelerate investigations of the molecular m作者: 密切關(guān)系 時(shí)間: 2025-3-22 19:10 作者: calamity 時(shí)間: 2025-3-22 23:30 作者: 接觸 時(shí)間: 2025-3-23 05:28
In Silico Prediction of the Binding, Folding, Insertion, and Overall Stability of Membrane-Active Peelivery, gene delivery, and antimicrobials and antibiotics. The broad appeal of MAPs is that they are infinitely variable, relatively low cost, and biocompatible. However, experimentally characterizing the specific properties of a MAP or its many variants is a low-resolution and potentially time-con作者: 尊重 時(shí)間: 2025-3-23 06:18 作者: detach 時(shí)間: 2025-3-23 10:56 作者: inferno 時(shí)間: 2025-3-23 15:13 作者: Trochlea 時(shí)間: 2025-3-23 18:20 作者: cultivated 時(shí)間: 2025-3-23 23:57
In Silico Prediction of the Binding, Folding, Insertion, and Overall Stability of Membrane-Active Peations: prior knowledge of the system, understanding the strengths and weaknesses of molecular mechanics force fields, proper construction and equilibration of the system, realistically estimating both experimental and computational timescales, and leveraging analysis to make direct comparisons to e作者: 頂點(diǎn) 時(shí)間: 2025-3-24 06:23 作者: Geyser 時(shí)間: 2025-3-24 10:13 作者: Generic-Drug 時(shí)間: 2025-3-24 14:21 作者: BILIO 時(shí)間: 2025-3-24 18:27
https://doi.org/10.1007/978-3-663-13026-0on protocols for preparing routine biomolecular systems containing proteins, including both a globular protein in aqueous solvent and a transmembrane model peptide in a phospholipid bilayer. Details and example input files are provided for preparation of the simulation system using CHARMM, performin作者: 變色龍 時(shí)間: 2025-3-24 22:39 作者: debble 時(shí)間: 2025-3-25 01:03
Irina S. Moreira,Miguel Machuqueiro,Joana Mour?oIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts作者: PIZZA 時(shí)間: 2025-3-25 06:37
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/232232.jpg作者: mediocrity 時(shí)間: 2025-3-25 07:32
Computational Design of Membrane Proteins978-1-0716-1468-6Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: Hemiplegia 時(shí)間: 2025-3-25 15:27
Steuerarbitrage mit Wertpapieren,utical drug targets, their structural and functional information is still very scarce. Over the last years, in silico analysis and algorithm development were essential to characterize MPs and overcome some limitations of experimental approaches. The optimization and improvement of these methods rema作者: 止痛藥 時(shí)間: 2025-3-25 16:01 作者: Goblet-Cells 時(shí)間: 2025-3-25 23:34 作者: Watemelon 時(shí)間: 2025-3-26 00:21
https://doi.org/10.1007/978-3-662-66628-9 systems—the artificial rewiring of biological pathways. Here we describe the three-dimensional structure-based design of “rewiring” mutations using the FoldX force field. Specifically, we provide the protocol for the design and selection of interface mutations in three Ras-effector complex structur作者: 靦腆 時(shí)間: 2025-3-26 08:15
Steuerbegünstigte Kapitalanlagene target of about 30% of presently available pharmaceutical drugs. The recent boom in GPCR structures led to the structural resolution of 57 unique receptors in different states (39 receptors in inactive state only, 2 receptors in active state only and 16 receptors in different activation states). I作者: EVADE 時(shí)間: 2025-3-26 10:24 作者: 新奇 時(shí)間: 2025-3-26 14:42
,Der wirtschaftliche Gesch?ftsbetrieb,ocated protein molecules, the method outputs a list of potential complexes sorted by energy criteria. The program includes three steps: docking, refinement, and re-ranking of the results. All three docking steps have been customized to the membrane environment in order to improve performance and red作者: Ligneous 時(shí)間: 2025-3-26 16:57
Abhandlungen zur Mittelstandsforschungof lipid-modified proteins in model membranes. After outlining some key practical considerations when planning such simulations, we survey resources and techniques to obtain force field parameters for nonconventional amino acids, such as posttranslationally lipid-modified amino acids that are unique作者: adulterant 時(shí)間: 2025-3-26 22:30 作者: 描繪 時(shí)間: 2025-3-27 03:09
Steuerberaterprüfung - Schwerpunkt "Recht" protein surface. A very effective way to quantify these changes is by calculating the p.. values of the protein’s titratable residues, which can be regarded as electrostatic probes. To achieve this, we need to take advantage of the fast and reliable p.. calculators developed for globular proteins a作者: GNAW 時(shí)間: 2025-3-27 07:50 作者: concubine 時(shí)間: 2025-3-27 10:50
https://doi.org/10.1007/978-3-663-13026-0. The increasing emergence of these simulations is a result of continual refinement against a range of theoretical and empirical target data, optimization of software algorithms for higher performance, and availability of graphical processing unit hardware to further accelerate the simulations. Pola作者: 生命層 時(shí)間: 2025-3-27 14:28 作者: Eclampsia 時(shí)間: 2025-3-27 18:44 作者: 頌揚(yáng)國(guó)家 時(shí)間: 2025-3-27 22:33 作者: gonioscopy 時(shí)間: 2025-3-28 03:39 作者: TRAWL 時(shí)間: 2025-3-28 09:18 作者: bypass 時(shí)間: 2025-3-28 11:04
Membrane Protein Engineering with Rosettaware: (1) ΔΔ. calculations for single point mutations and (2) sequence optimization in different membrane lipid compositions. These modular protocols are easily adaptable for more complex problems and serve as a foundation for efficient membrane protein engineering calculations.作者: 言行自由 時(shí)間: 2025-3-28 17:10
Memdock: An α-Helical Membrane Protein Docking Algorithmuce program run-time. In this chapter, we describe the application of our web server, referred to as Memdock, for prediction of the docking complex for a pair of input membrane protein structures. Memdock is freely available for academic?users without registration at ..作者: anus928 時(shí)間: 2025-3-28 22:42 作者: 冷峻 時(shí)間: 2025-3-29 00:42 作者: forager 時(shí)間: 2025-3-29 03:48 作者: Panther 時(shí)間: 2025-3-29 09:02
,Der wirtschaftliche Gesch?ftsbetrieb,uce program run-time. In this chapter, we describe the application of our web server, referred to as Memdock, for prediction of the docking complex for a pair of input membrane protein structures. Memdock is freely available for academic?users without registration at ..作者: fibula 時(shí)間: 2025-3-29 11:46
Steuerberaterprüfung - Schwerpunkt "Recht"nd adapt them to include the explicit effects of membranes. Here, we provide a detailed linear response approximation protocol that uses our own software (PypKa) to calculate reliable p.. values from short MD simulations of membrane proteins.作者: Hippocampus 時(shí)間: 2025-3-29 18:58 作者: 占線 時(shí)間: 2025-3-29 20:21 作者: 確定的事 時(shí)間: 2025-3-30 01:18 作者: 使顯得不重要 時(shí)間: 2025-3-30 07:37 作者: ordain 時(shí)間: 2025-3-30 10:20
Molecular Dynamics Simulation of Lipid-Modified Signaling Proteinsteins will be provided, using RAS proteins as illustrative examples. Throughout the chapter, we highlight the main advantages and limitations of simulating RAS and related lipid-modified G-proteins in biomimetic membranes.作者: 責(zé)任 時(shí)間: 2025-3-30 13:55
Poor Person’s pH Simulation of Membrane Proteinss of structure and function are provided using two case studies, namely those of bioenergetic complexes: NADH dehydrogenase (complex I) and V. domain of V-type ATPase. The hybrid MCCE-MD pipeline has allowed the discovery of hydrogen bond networks, ligand binding pathways, and disease-causing mutations.
