標(biāo)題: Titlebook: Clinical Pharmacology in Psychiatry; Selectivity in Psych Svein G. Dahl (Professor of Pharmacology),Lars F. Conference proceedings 1987 Sp [打印本頁] 作者: FAULT 時(shí)間: 2025-3-21 19:20
書目名稱Clinical Pharmacology in Psychiatry影響因子(影響力)
書目名稱Clinical Pharmacology in Psychiatry影響因子(影響力)學(xué)科排名
書目名稱Clinical Pharmacology in Psychiatry網(wǎng)絡(luò)公開度
書目名稱Clinical Pharmacology in Psychiatry網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Clinical Pharmacology in Psychiatry被引頻次
書目名稱Clinical Pharmacology in Psychiatry被引頻次學(xué)科排名
書目名稱Clinical Pharmacology in Psychiatry年度引用
書目名稱Clinical Pharmacology in Psychiatry年度引用學(xué)科排名
書目名稱Clinical Pharmacology in Psychiatry讀者反饋
書目名稱Clinical Pharmacology in Psychiatry讀者反饋學(xué)科排名
作者: 音樂會 時(shí)間: 2025-3-21 21:25
Synthesis of New Peptides Based on Models of Receptor-Bound Conformations mediate a wide range of endocrine, motor, and behavioral responses (Snyder 1980; Krieger 1983). These substances control such diverse functions as growth, reproduction, digestion, metabolism, and the dynamics of the cardiovascular system. Immunostaining techniques have been used to visualize and m作者: comely 時(shí)間: 2025-3-22 03:50 作者: 宏偉 時(shí)間: 2025-3-22 04:56 作者: 箴言 時(shí)間: 2025-3-22 11:29
β-Carbolines: New Insights into the Clinical Pharmacology of Benzodiazepine Receptor Ligandsns with these binding sites. This major finding was followed by numerous biochemical, histological, and electrophysiological studies, which then showed that the benzodiazepine receptor is an allosteric modulatory site that is functionally coupled to, and located on, a subgroup of GABA receptors that作者: intangibility 時(shí)間: 2025-3-22 16:36 作者: intangibility 時(shí)間: 2025-3-22 19:11
Correlating Pharmacokinetics and Pharmacodynamics of Benzodiazepines: Problems and Assumptionsable knowledge of their pharmacokinetic properties in humans and in other species (Klotz et al. 1980; Guentert 1984; Greenblatt et al. 1983a,b; Greenblatt and Shader 1985 a). These data include the kinetic properties in healthy individuals, the influence of physiologic states and disease processes o作者: 領(lǐng)先 時(shí)間: 2025-3-22 23:36 作者: 碎石 時(shí)間: 2025-3-23 03:49 作者: Trigger-Point 時(shí)間: 2025-3-23 07:22
Abuse Liability of Triazolam: Experimental Measurements in Animals and Humans the untoward effects of abusing the drug). These two senses of abuse liability correspond directly to two major characteristics of drugs of abuse: (a) they have . (they have the capacity to maintain drug self-administration) and (b) they produce . (they have the capacity to harm the individual and/作者: Esophagus 時(shí)間: 2025-3-23 12:33
Clinical Studies of “Specific” Anxiolytics as Therapeutic Agentsh involved almost 10000 persons, estimated that 8.3% of the adult U. S. population had suffered from anxiety disorders during the past 6 months. The two next highest diagnostic categories were alcohol and drug abuse (6.4%) and depression (6.0%), followed by schizophrenia (1.0%). Interestingly, howev作者: 清楚 時(shí)間: 2025-3-23 14:32
Regulation of Beta Adrenergic and Serotonin-S2 Receptors in Brain by Electroconvulsive Shock and Sers of beta adrenergic receptors (Banerjee et al. 1977; Wolfe et al. 1978; Sarai et al. 1978; Bergstrom and Kellar 1979 a) and decreases in the number of serotonin-S2 (5-HT-2) receptors (Peroutka and Snyder 1980; Kellar et al. 1981 a). The decrease in the density of beta adrenergic receptors is associ作者: 縮短 時(shí)間: 2025-3-23 20:55 作者: 擔(dān)憂 時(shí)間: 2025-3-23 23:22 作者: 笨拙處理 時(shí)間: 2025-3-24 04:20
Selective Amine Oxidase Inhibitors: Basic to Clinical Studies and Backre all nonselective agents. They have marked effects on the metabolism of over 15 different monoamines, including major brain neurotransmitters (norepinephrine, dopamine, and serotonin) and on that of many other amines, which may act as co-transmitters, false transmitters, amine-releasing agents, or作者: 吹牛需要藝術(shù) 時(shí)間: 2025-3-24 09:10 作者: LEERY 時(shí)間: 2025-3-24 11:08
Redlicher Erwerb vom Nichtberechtigteninephrine, dopamine, and serotonin) and on that of many other amines, which may act as co-transmitters, false transmitters, amine-releasing agents, or neuromodulators (e.g., tryptamine, tyramine, octopamine, and phenylethylamine).作者: 繁殖 時(shí)間: 2025-3-24 16:09 作者: nautical 時(shí)間: 2025-3-24 22:58
Eigentum: Begriff, Inhalt, Artense correlations reflect the effective concentration of the drug in the critical biophase rather than the critical features necessary for bimolecular recognition. We would like to concentrate on what can be deduced regarding bimolecular recognition from structure-activity data.作者: 存心 時(shí)間: 2025-3-25 03:13
Molecular Modeling in Drug Designse correlations reflect the effective concentration of the drug in the critical biophase rather than the critical features necessary for bimolecular recognition. We would like to concentrate on what can be deduced regarding bimolecular recognition from structure-activity data.作者: Complement 時(shí)間: 2025-3-25 04:40
Einleitung in das Recht des Besitzesonged period of impairment for lorazepam (Seppala et al. 1976), although the elimination half-lives (t.) of diazepam and its active metabolite .-desmethyldiazepam (Mandelli et al. 1978) are over twice as long as that of lorazepam, which has no active metabolites.作者: Digitalis 時(shí)間: 2025-3-25 08:46
Comparative Pharmacodynamics of Benzodiazepinesonged period of impairment for lorazepam (Seppala et al. 1976), although the elimination half-lives (t.) of diazepam and its active metabolite .-desmethyldiazepam (Mandelli et al. 1978) are over twice as long as that of lorazepam, which has no active metabolites.作者: 必死 時(shí)間: 2025-3-25 12:37
Eigentum: Begriff, Inhalt, Artenap the distribution of peptides, in particular neuronal pathways. Many of these substances have also been shown to occur in peripheral regions, such as the gastrointestinal tract. The role of many of these agents is largely unknown, but their potential utility in therapy is great.作者: deriver 時(shí)間: 2025-3-25 15:52
Unmittelbarer Besitz; Erwerb und Verlust gate a chloride channel. The benzodiazepines’ primary target is thus located on neurons that are modulated by the GABAergic neurons containing the GABA-benzodiazepine receptor-chloride channel (GBC) complex. (For review see P. Skolnick et al., this volume.)作者: 沉默 時(shí)間: 2025-3-25 20:29
Schutz des unmittelbaren Besitzesn benzodiazepine disposition, and alterations in kinetics due to drug interactions. The study of benzodiazepine pharmacokinetics has elucidated much about the general mechanisms controlling the biotransformation of foreign chemicals, and factors influencing drug disposition.作者: 能量守恒 時(shí)間: 2025-3-26 01:32 作者: NATAL 時(shí)間: 2025-3-26 08:15 作者: Eulogy 時(shí)間: 2025-3-26 10:39 作者: Increment 時(shí)間: 2025-3-26 13:03 作者: 郊外 時(shí)間: 2025-3-26 20:50 作者: Insensate 時(shí)間: 2025-3-26 21:24
Correlating Pharmacokinetics and Pharmacodynamics of Benzodiazepines: Problems and Assumptionsn benzodiazepine disposition, and alterations in kinetics due to drug interactions. The study of benzodiazepine pharmacokinetics has elucidated much about the general mechanisms controlling the biotransformation of foreign chemicals, and factors influencing drug disposition.作者: bronchodilator 時(shí)間: 2025-3-27 02:40
Benzodiazepine-Serotonin Interactions in Manses that are more relevant to the clinical, anxiolytic/anticonvulsant effects than the sedative/anesthetic ones. For instance, Collinge et al. (1983) showed that low doses of BDZ reduced 5HT turnover in the rat. This effect persisted for at least 3 weeks.作者: 富饒 時(shí)間: 2025-3-27 05:49 作者: Pruritus 時(shí)間: 2025-3-27 11:12 作者: 靦腆 時(shí)間: 2025-3-27 17:18 作者: 反對 時(shí)間: 2025-3-27 19:30 作者: Commonwealth 時(shí)間: 2025-3-27 22:26
Clinical Studies of “Specific” Anxiolytics as Therapeutic Agents (5.1%). In this household survey it was again observed that only a relatively small percentage of those suffering from psychic distress and given a DSM III diagnosis as derived from the Hopkins Symptom Checklist criteria actually were treated for anxiety (Uhlenhuth et al. 1983).作者: 下邊深陷 時(shí)間: 2025-3-28 04:25
Regulation of Beta Adrenergic and Serotonin-S2 Receptors in Brain by Electroconvulsive Shock and Serahorski 1985). The decrease in serotonin-S. receptors may be linked to decreases in serotonin-mediated behavioral responses, but the high affinity of most of the antidepressants tested for the serotonin-S.-binding site in vitro and the possibility that the drugs block these receptors clouds this iss作者: 急急忙忙 時(shí)間: 2025-3-28 07:48 作者: 水槽 時(shí)間: 2025-3-28 14:09
Unmittelbarer Besitz; Erwerb und Verlustnal coupling of the recognition components of the benzo-diazepine-GABA receptor chloride ionophore complex (supramolecular complex) and summarize recent findings from our laboratory demonstrating that the “effector” component of this complex, the chloride ionophore, is rapidly altered by stress.作者: 才能 時(shí)間: 2025-3-28 14:59 作者: Occlusion 時(shí)間: 2025-3-28 22:09 作者: 消滅 時(shí)間: 2025-3-29 02:13
Eigentum: Begriff, Inhalt, Arten (5.1%). In this household survey it was again observed that only a relatively small percentage of those suffering from psychic distress and given a DSM III diagnosis as derived from the Hopkins Symptom Checklist criteria actually were treated for anxiety (Uhlenhuth et al. 1983).作者: 畫布 時(shí)間: 2025-3-29 03:32
Eigentum: Begriff, Inhalt, Artenahorski 1985). The decrease in serotonin-S. receptors may be linked to decreases in serotonin-mediated behavioral responses, but the high affinity of most of the antidepressants tested for the serotonin-S.-binding site in vitro and the possibility that the drugs block these receptors clouds this iss作者: 去掉 時(shí)間: 2025-3-29 08:14
Eigentum: Begriff, Inhalt, Artenstributed in the brain, particularly in the cortex. The possibility that α.-autoreceptor antagonism might lead to antidepressant properties has stimulated the development of a number of putative therapeutic agents, which vary widely in their potency and selectivity (Pinder 1985 a, b).作者: 別名 時(shí)間: 2025-3-29 12:51
0931-6795 nowned neuropsychopharmacologists to address the problem of selectivity in psychotropic drug action and to try to reconcile the amazing advances in basic precli978-3-642-71290-6978-3-642-71288-3Series ISSN 0931-6795 作者: Mitigate 時(shí)間: 2025-3-29 16:13 作者: Vaginismus 時(shí)間: 2025-3-29 22:59
Conference proceedings 1987 times not so subtle) organizational skills. Nevertheless, in Earl‘s memory the organizers proceeded to invite a group of internationally renowned neuropsychopharmacologists to address the problem of selectivity in psychotropic drug action and to try to reconcile the amazing advances in basic precli作者: 暫時(shí)中止 時(shí)間: 2025-3-30 02:30 作者: Canyon 時(shí)間: 2025-3-30 06:21
Eigentum: Begriff, Inhalt, Artens mediate a wide range of endocrine, motor, and behavioral responses (Snyder 1980; Krieger 1983). These substances control such diverse functions as growth, reproduction, digestion, metabolism, and the dynamics of the cardiovascular system. Immunostaining techniques have been used to visualize and m作者: 疲勞 時(shí)間: 2025-3-30 09:24
Einleitung und Grunds?tze des Sachenrechtsh the receptor sites, it is of primary importance to elucidate the characteristic structural and conformational features of these compounds. This can be accomplished by analysis of SAR data (structure-activity relationship) for different types of drugs and related compounds.作者: 愛國者 時(shí)間: 2025-3-30 13:25
Unmittelbarer Besitz; Erwerb und Verluste molecular pharmacology of benzodiazepines, barbiturates, and related compounds. Within the past 5 years it has become apparent that the benzodiazepine receptor is one component of a “supramolecular complex” consisting of multiple allosteric recognition sites which play a critical role in the regul作者: mechanism 時(shí)間: 2025-3-30 17:19 作者: FLAG 時(shí)間: 2025-3-30 23:36
Einleitung in das Recht des Besitzese extensive clinical experience with these drugs it is only in the past few years that we have developed any understanding of their underlying molceular mechanisms of action. It is now known that specific receptors for benzodiazepines are present in brain and that these receptors are functionally li作者: Gobble 時(shí)間: 2025-3-31 03:08 作者: cancellous-bone 時(shí)間: 2025-3-31 07:38 作者: 遺產(chǎn) 時(shí)間: 2025-3-31 11:21
Einleitung in das Recht des Besitzesal. 1983, 1985; Lader 1979; Ziegler et al. 1983). For diazepam the rapid onset of acute tolerance follows the peak behavioral effect; that is, impairment of performance in cognitive-neuromotor tests declines considerably faster than the corresponding serum drug concentration (Ellinwood et al. 1983, 作者: Headstrong 時(shí)間: 2025-3-31 16:39
Eigentumserwerb vom Berechtigten the untoward effects of abusing the drug). These two senses of abuse liability correspond directly to two major characteristics of drugs of abuse: (a) they have . (they have the capacity to maintain drug self-administration) and (b) they produce . (they have the capacity to harm the individual and/
