標(biāo)題: Titlebook: Clinical Applications of Immunotoxins; Arthur E. Frankel (Associate Professor of Medicine Book 1998 The Editor(s) (if applicable) and The [打印本頁(yè)] 作者: vitamin-D 時(shí)間: 2025-3-21 18:10
書目名稱Clinical Applications of Immunotoxins影響因子(影響力)
書目名稱Clinical Applications of Immunotoxins影響因子(影響力)學(xué)科排名
書目名稱Clinical Applications of Immunotoxins網(wǎng)絡(luò)公開(kāi)度
書目名稱Clinical Applications of Immunotoxins網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書目名稱Clinical Applications of Immunotoxins被引頻次
書目名稱Clinical Applications of Immunotoxins被引頻次學(xué)科排名
書目名稱Clinical Applications of Immunotoxins年度引用
書目名稱Clinical Applications of Immunotoxins年度引用學(xué)科排名
書目名稱Clinical Applications of Immunotoxins讀者反饋
書目名稱Clinical Applications of Immunotoxins讀者反饋學(xué)科排名
作者: 法律的瑕疵 時(shí)間: 2025-3-21 20:44
The Emerging Role of Ricin A-Chain Immunotoxins in Leukemia and Lymphoma,timately die of their disease. The major reason for this poor outcome is the persistence or selection of cells which are refractory to conventional treatment. These cells might be eradicated by new immunotherapeutic agents with different modes of action. In this regard, monoclonal antibodies (Moabs)作者: 脫離 時(shí)間: 2025-3-22 04:15
Clinical Trials with Blocked Ricin Immunotoxins,unately, even with the development of innovative multi-drug treatment regimens and the increasing availability of both autologous bone marrow transplantation (ABMT) and peripheral blood stem cell transplantation (PBSCT), the clinician lacks the necessary tools to successfully combat the progression 作者: 油氈 時(shí)間: 2025-3-22 06:07 作者: invade 時(shí)間: 2025-3-22 10:03
Diphtheria Toxin Fusion Proteins,ting of monoclonal antibodies chemically linked through a disulfide bond to a plant or bacterial toxin or radionuclide. Instability of the chemical conjugation of some of the earlier immunotoxins led to the concept of using protein engineering and recombinant DNA to assemble fusion genes combining t作者: Trigger-Point 時(shí)間: 2025-3-22 14:10 作者: Trigger-Point 時(shí)間: 2025-3-22 17:34 作者: 北極人 時(shí)間: 2025-3-22 23:04 作者: 絕食 時(shí)間: 2025-3-23 04:54 作者: NOTCH 時(shí)間: 2025-3-23 09:12
T. E. Cooke,J. Matatko,D. C. Staffordon of so many colleagues in this field in this book has been a reflection both of the kindness and friendliness of the individuals as well as their commitment to working together to develop a new class of human therapeutics.作者: 名字的誤用 時(shí)間: 2025-3-23 11:35
Clinical Trials with Blocked Ricin Immunotoxins,of malignancy in the majority of patients. Furthermore, substantial morbidity and potential mortality is associated with the use of these aggressive treatment programs. New anti-tumor agents ideally should circumvent the two major limitations of current therapy: devastating nonspecific side effects and tumor cell resistance.作者: 燈絲 時(shí)間: 2025-3-23 14:33 作者: Glower 時(shí)間: 2025-3-23 19:13
T. E. Cooke,J. Matatko,D. C. Stafford as growth factors or monoclonal antibodies, can be linked to protein toxins by random chemical modification of lysine or sulfhydral residues (. et al. 1987) or by fusion of the new protein domains at the COOH- or NH.-terminal of the protein by molecular biology techniques (. et al. 1986).作者: 全等 時(shí)間: 2025-3-23 22:45
Immunotoxins for Brain Tumor Therapy, as growth factors or monoclonal antibodies, can be linked to protein toxins by random chemical modification of lysine or sulfhydral residues (. et al. 1987) or by fusion of the new protein domains at the COOH- or NH.-terminal of the protein by molecular biology techniques (. et al. 1986).作者: 拾落穗 時(shí)間: 2025-3-24 03:07
Jocelyn Spence,Stuart Andrews,David Frohlichften linked to radioisotopes or toxins to increase their toxicity. Immunotoxins (ITs) are constructed by chemically or genetically linking the antibody moiety to a potent bacterial or plant toxin. To date, the most widely used toxin is ricin, which is derived from the seeds of . (castor bean).作者: hieroglyphic 時(shí)間: 2025-3-24 07:11 作者: 刺穿 時(shí)間: 2025-3-24 12:42 作者: 漂浮 時(shí)間: 2025-3-24 15:15
Jocelyn Spence,Stuart Andrews,David Frohlichins that act catalytically to kill cells, bacterial and plant toxins are often employed as the cell-killing component of immunotoxins. Here we provide background information into the structure-function relationships of toxins and discuss how they can be combined with cell-binding antibodies or other ligands to generate immunotoxins.作者: 有斑點(diǎn) 時(shí)間: 2025-3-24 22:03
Introduction,ins that act catalytically to kill cells, bacterial and plant toxins are often employed as the cell-killing component of immunotoxins. Here we provide background information into the structure-function relationships of toxins and discuss how they can be combined with cell-binding antibodies or other ligands to generate immunotoxins.作者: AGATE 時(shí)間: 2025-3-25 02:49
Book 1998 . . . . . . . . . . . . . . . . . . . . 2 2. 2 Binding. . . . . . . . . . . . . . . . . . . . . . . . . 3 3 Intracellular Processing - Cleavage and Reduction . . . . . . 4 3. 1 Cytosolic Activity . . . . . . . . . . . . . . . . 5 4 Immunotoxin Design and Testing. 6 5 Conclusion. . 8 References. . .作者: Calculus 時(shí)間: 2025-3-25 04:09
Tax Effects in Gilt-edged Security Valuationorin, by contrast, is a single chain, ribosome inactivating protein (rip) which consequently has no lectin-like binding activity and moreover is not glycosylated in the native form (. et al. 1983). Saporin is therefore very considerably safer to handle and can be used in its native form without the 作者: Sarcoma 時(shí)間: 2025-3-25 11:25 作者: 無(wú)聊的人 時(shí)間: 2025-3-25 14:03 作者: 占卜者 時(shí)間: 2025-3-25 16:23
Saporin Immunotoxins,orin, by contrast, is a single chain, ribosome inactivating protein (rip) which consequently has no lectin-like binding activity and moreover is not glycosylated in the native form (. et al. 1983). Saporin is therefore very considerably safer to handle and can be used in its native form without the 作者: INCH 時(shí)間: 2025-3-25 21:22 作者: 不可磨滅 時(shí)間: 2025-3-26 04:02 作者: ANT 時(shí)間: 2025-3-26 05:20 作者: Aspiration 時(shí)間: 2025-3-26 10:40
Book 1998oxins. Here we provide background information into the structure-func- tion relationships of toxins and discuss how they can be combined with cell-binding antibodies or other ligands to generate immunotoxins. Bacterial and plant toxins (e. g. , diphtheria toxin, Pseudomonas exotoxin and ricin) are a作者: 受人支配 時(shí)間: 2025-3-26 15:45
0070-217X h cell-binding antibodies or other ligands to generate immunotoxins. Bacterial and plant toxins (e. g. , diphtheria toxin, Pseudomonas exotoxin and ricin) are a978-3-642-72155-7978-3-642-72153-3Series ISSN 0070-217X Series E-ISSN 2196-9965 作者: Excise 時(shí)間: 2025-3-26 17:27 作者: 擔(dān)心 時(shí)間: 2025-3-26 21:03 作者: Introvert 時(shí)間: 2025-3-27 01:06
Jocelyn Spence,Stuart Andrews,David Frohlich spread and deprivation of key nutrients, the goal of immunotoxin treatment is the direct killing of malignant cells. Because they are enzymatic proteins that act catalytically to kill cells, bacterial and plant toxins are often employed as the cell-killing component of immunotoxins. Here we provide作者: interior 時(shí)間: 2025-3-27 08:32
Jocelyn Spence,Stuart Andrews,David Frohlichtimately die of their disease. The major reason for this poor outcome is the persistence or selection of cells which are refractory to conventional treatment. These cells might be eradicated by new immunotherapeutic agents with different modes of action. In this regard, monoclonal antibodies (Moabs)作者: 假裝是你 時(shí)間: 2025-3-27 10:53 作者: 植物群 時(shí)間: 2025-3-27 16:05 作者: 變化無(wú)常 時(shí)間: 2025-3-27 17:47
Tax Effects in Gilt-edged Security Valuationting of monoclonal antibodies chemically linked through a disulfide bond to a plant or bacterial toxin or radionuclide. Instability of the chemical conjugation of some of the earlier immunotoxins led to the concept of using protein engineering and recombinant DNA to assemble fusion genes combining t作者: 連詞 時(shí)間: 2025-3-27 22:37 作者: squander 時(shí)間: 2025-3-28 02:18
T. E. Cooke,J. Matatko,D. C. Staffordbacterial proteins with the tumor-specific binding capacity of monoclonal antibodies. Toxins such as ricin and diphtheria toxin have been linked to new cell surface binding moieties in order to target tumor cells for destruction. To the extent that tumor cells have cell surface receptors that distin作者: limber 時(shí)間: 2025-3-28 07:28 作者: 吝嗇性 時(shí)間: 2025-3-28 12:53
https://doi.org/10.1007/978-3-642-72153-3Bakterium; bacteria; clinical trial; clinical trials; immunotherapy; leukemia; lymphoma; pharmacology; poiso作者: 碎石 時(shí)間: 2025-3-28 17:48
978-3-642-72155-7The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
