作者: hallow 時(shí)間: 2025-3-22 00:17 作者: 責(zé)任 時(shí)間: 2025-3-22 01:42 作者: 不透明性 時(shí)間: 2025-3-22 05:20
K. Purvis,M. Parvinen,K. Gautvik,V. Hanssone CTC from cancer patients’ peripheral blood—the affinity-based enrichment of CTC. We briefly discuss the different technologies utilizing antibodies to capture CTC based on specific antigen expression. Then we address the downstream molecular and functional characterization of CTC by utilizing thes作者: Malleable 時(shí)間: 2025-3-22 11:37
Max H. Schreier,Theophil Staehelinancer management (Cristofanilli et al., N Engl J Med 351(8):781–791, 2004; Cohen et al., J Clin Oncol 26(19):3213–3221, 2008; de Bono et al., Clin Cancer Res, 14(19):6302–6309, 2008; Poveda et al., Gynecol Oncol, 122(3):567–572, 2011). However, the technical hurdle for studying CTCs is their rare pr作者: 箴言 時(shí)間: 2025-3-22 15:16 作者: 箴言 時(shí)間: 2025-3-22 17:30
https://doi.org/10.1007/978-1-4615-1651-4ls” (CSCs). These cells have the ability to self-renew and to generate heterogeneous populations that constitute the tumor bulk. Preclinical studies have demonstrated that CSCs mediate tumor metastasis and resistance to chemotherapy and radiation therapy. CSC biomarkers have been identified and both作者: Volatile-Oils 時(shí)間: 2025-3-22 21:13
Helge Gro?hans,Saibal Chatterjeecer recurrence remain poorly understood, failure to completely eliminate dormant micrometastases and solitary metastatic cells is believed to be a major contributor. Thus, while not of initial clinical concern, metastatic dormancy is still a significant clinical problem. The emerging use of circulat作者: lacrimal-gland 時(shí)間: 2025-3-23 02:26 作者: 無(wú)底 時(shí)間: 2025-3-23 07:19
https://doi.org/10.1007/978-4-431-65880-1ire the morphology of solitary migratory cells, has been implicated in the progression of carcinoma. EMT may contribute to the formation of cancer stem cells, evasion of immune surveillance, and induction of resistance to chemotherapeutics and targeted therapeutics. Metastasis is governed by a compl作者: 遷移 時(shí)間: 2025-3-23 13:23 作者: 填料 時(shí)間: 2025-3-23 17:34 作者: 阻擋 時(shí)間: 2025-3-23 19:53 作者: 內(nèi)行 時(shí)間: 2025-3-24 00:46
Luis Olmos,Ignacio J. Pérez-Arriagatting of metastatic disease CTC have the potential to reveal important insights into the biology and behavior of the cells undergoing the metastatic process and contributing to the resistance and progression of disease over time. In breast cancer the enumeration of CTC has been demonstrated to be a 作者: hypertension 時(shí)間: 2025-3-24 02:55 作者: 不規(guī)則 時(shí)間: 2025-3-24 06:56 作者: Density 時(shí)間: 2025-3-24 12:27
Regulation und künftige Technikentwicklungo center stage in diagnostic and translational research, largely owing to advances in isolation technology and increasing sensitivity of the various genomic, transcriptomic, and proteomic platforms. As we enter the era of personalized medicine, it is foreseeable that CTCs will become an integral com作者: Acupressure 時(shí)間: 2025-3-24 17:30
Significance of Studying Circulating Tumor Cellsxtensively studied only in the last decade or so. Understanding the biological and clinical impact of CTC is likely to reveal important information of the metastatic process and contribute to better management of cancer. We briefly discuss here the current clinical utility of CTC and their emerging clinical applications.作者: BET 時(shí)間: 2025-3-24 22:56 作者: 比喻好 時(shí)間: 2025-3-25 00:54 作者: 谷類 時(shí)間: 2025-3-25 04:48
Richard J. Cote,Ram H. DatarProvides a blueprint on how circulating tumor cells can be employed in the future.Features authors from diverse backgrounds in biology, biochemistry, and medical oncology?.Delivers a “one-stop” text t作者: palpitate 時(shí)間: 2025-3-25 11:10 作者: 主動(dòng) 時(shí)間: 2025-3-25 13:25
Helge Gro?hans,Saibal Chatterjeeard to metastasis biology and treatment. We also consider the clinical impact of monitoring for CTCs in the absence of symptomatic tumor recurrence and what is needed for such an approach to providing “actionable” information that will improve patient outcome.作者: 生銹 時(shí)間: 2025-3-25 17:38
microRNA Biogenesis and Function, regulated, both naturally in the body and therapeutically. A better understanding of mechanisms by which dormancy can be regulated may suggest new therapeutic approaches to either eliminate dormant cancer cells or promote the maintenance of dormancy.作者: Transfusion 時(shí)間: 2025-3-25 22:00 作者: elucidate 時(shí)間: 2025-3-26 01:46 作者: cultivated 時(shí)間: 2025-3-26 05:15 作者: PLUMP 時(shí)間: 2025-3-26 09:09 作者: hemoglobin 時(shí)間: 2025-3-26 15:27
K. Purvis,M. Parvinen,K. Gautvik,V. Hanssonto capture CTC based on specific antigen expression. Then we address the downstream molecular and functional characterization of CTC by utilizing these technologies. We also discuss the limitations of affinity-based CTC enrichment.作者: 摘要 時(shí)間: 2025-3-26 19:30 作者: Hippocampus 時(shí)間: 2025-3-26 23:57 作者: STIT 時(shí)間: 2025-3-27 02:04 作者: degradation 時(shí)間: 2025-3-27 08:52
Regulation of the Pharmaceutical Industrye as groundwork for future efforts in discovery and development of novel CTC-based genomic biomarkers. Further molecular profiling of CTCs may provide novel insights into mechanisms of disease progression and tumor evolution, and open new avenues for personalized treatment.作者: Heart-Attack 時(shí)間: 2025-3-27 13:19
Book 20161st editionhe basic concepts behind circulating tumor cells (CTCs), metastatic biology, and potential applications as to how CTCs can be used in diagnostic biomarkers..CTCs are cells that have detached from the primary tumor and circulate in the bloodstream. Such cells may become "seeds" for the growth of addi作者: 使人煩燥 時(shí)間: 2025-3-27 16:46 作者: 吸引力 時(shí)間: 2025-3-27 19:47
Significance of Studying Circulating Tumor Cellsxtensively studied only in the last decade or so. Understanding the biological and clinical impact of CTC is likely to reveal important information of the metastatic process and contribute to better management of cancer. We briefly discuss here the current clinical utility of CTC and their emerging 作者: airborne 時(shí)間: 2025-3-27 22:28 作者: CLAMP 時(shí)間: 2025-3-28 05:36
Size-Based and Non-Affinity Based Microfluidic Devices for Circulating Tumor Cell Enrichment and Chaancer management (Cristofanilli et al., N Engl J Med 351(8):781–791, 2004; Cohen et al., J Clin Oncol 26(19):3213–3221, 2008; de Bono et al., Clin Cancer Res, 14(19):6302–6309, 2008; Poveda et al., Gynecol Oncol, 122(3):567–572, 2011). However, the technical hurdle for studying CTCs is their rare pr作者: DEFER 時(shí)間: 2025-3-28 10:09 作者: interrupt 時(shí)間: 2025-3-28 10:55
Cancer Stem Cells and Circulating Tumor Cells: Molecular Markers, Isolation Techniques, and Clinicalls” (CSCs). These cells have the ability to self-renew and to generate heterogeneous populations that constitute the tumor bulk. Preclinical studies have demonstrated that CSCs mediate tumor metastasis and resistance to chemotherapy and radiation therapy. CSC biomarkers have been identified and both作者: 天賦 時(shí)間: 2025-3-28 15:22 作者: palette 時(shí)間: 2025-3-28 19:00
Prevention of Conversion of Tumor Dormancy into Proliferative Metastasesprimary tumor. Clinical tumor dormancy thus creates uncertainty for cancer patients and their physicians, who cannot be certain that their cancer will not recur. We have a poor understanding about which individual patients are at risk for cancer recurrence following a period of tumor dormancy. Thus,作者: 含水層 時(shí)間: 2025-3-28 23:01 作者: MAUVE 時(shí)間: 2025-3-29 03:27
CTC Analysis: FISH, ISH, Array-CGH, and Other Molecular Assaysciated with therapeutic failure and drug resistance, posing considerable clinical challenges to finding effective treatment modalities. Therefore, assessing tumor heterogeneity is clinically important for developing novel and efficient targeted therapy concepts. Molecular analysis of circulating tum作者: 要求比…更好 時(shí)間: 2025-3-29 10:33
Genome-Wide Gene Copy Number Analysis of Circulating Tumor Cellshese extremely rare cells. Despite these challenges, there is a pressing need to elucidate the molecular characteristics of these tumor cells. In this chapter, we highlight recent studies on genome-wide gene copy number analysis of CTCs and comparisons with primary tumors. These initial studies serv作者: 擴(kuò)大 時(shí)間: 2025-3-29 12:27
Perspectives on the Functional Characterization and In Vitro Maintenance of Circulating Tumor CellsCs in peripheral blood samples has been associated with poor survival outcomes in various cancer types. As a readily accessible source of tumor tissue there is a vast potential to develop CTCs as a biomarker to advance cancer diagnosis, prognosis and the development of novel and targeted therapies. 作者: 流利圓滑 時(shí)間: 2025-3-29 18:19
Prognostic Implications of CTC in Breast Cancertting of metastatic disease CTC have the potential to reveal important insights into the biology and behavior of the cells undergoing the metastatic process and contributing to the resistance and progression of disease over time. In breast cancer the enumeration of CTC has been demonstrated to be a 作者: 審問(wèn) 時(shí)間: 2025-3-29 22:14 作者: accrete 時(shí)間: 2025-3-30 00:38 作者: Entreaty 時(shí)間: 2025-3-30 07:37
CTCs for Biomarker and Companion Diagnostic Developmento center stage in diagnostic and translational research, largely owing to advances in isolation technology and increasing sensitivity of the various genomic, transcriptomic, and proteomic platforms. As we enter the era of personalized medicine, it is foreseeable that CTCs will become an integral com作者: innovation 時(shí)間: 2025-3-30 09:06 作者: 廚房里面 時(shí)間: 2025-3-30 13:57 作者: 剛毅 時(shí)間: 2025-3-30 19:18
https://doi.org/10.1007/978-1-4615-1651-4iopsies to assess CSCs is difficult. Studies suggest that circulating tumor cells (CTCs) contain a highly enriched proportion of CSCs and thus monitoring these cells in blood may provide a . for CSC assessment in solid tumors. In parallel with developments of efficient CTC isolation technologies, as作者: 范圍廣 時(shí)間: 2025-3-30 21:05
