標(biāo)題: Titlebook: Circadian Rhythms in Bacteria and Microbiomes; Carl Hirschie Johnson,Michael Joseph Rust Book 2021 The Editor(s) (if applicable) and The A [打印本頁] 作者: 航天飛機 時間: 2025-3-21 17:05
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作者: mechanism 時間: 2025-3-21 22:20 作者: Foam-Cells 時間: 2025-3-22 03:19 作者: Alcove 時間: 2025-3-22 06:20 作者: 無法治愈 時間: 2025-3-22 09:00 作者: precede 時間: 2025-3-22 15:16
https://doi.org/10.1007/978-3-658-11328-5poorly understood. The cyanobacterial circadian clock exerts global gene regulations and oscillates intracellular metabolism. Manipulation of the circadian clock genes has proven to be an effective strategy for modulating the expression patterns of both endogenous and exogenous genes, driving either作者: precede 時間: 2025-3-22 21:03
g from cyanobacteria and circadian phenomena in other kinds of bacteria, to microbiomes has now given the field another major boost..This book is aimed at junior and senior researchers alike. Students978-3-030-72160-2978-3-030-72158-9作者: entail 時間: 2025-3-22 22:06 作者: Commodious 時間: 2025-3-23 03:55 作者: Mendicant 時間: 2025-3-23 06:18 作者: 緩解 時間: 2025-3-23 10:12
Diversity of Timing Systems in Cyanobacteria and Beyondhown. Moreover, homologs of cyanobacterial clock proteins are present in some Bacteria and Archaea, opening questions about the evolution of circadian rhythmicity in prokaryotes. In this chapter, we will highlight common aspects and key differences of timing systems that are based on Kai proteins.作者: Consensus 時間: 2025-3-23 14:44
An In Vitro Approach to Elucidating Clock-Modulating Metabolites and generated a phase advance and delay respectively, in agreement with the in vivo data. Additionally, magnesium showed a role in inhibiting the KaiC phosphorylation in vitro. A possible history of clock evolution can be suggested from this finding since magnesium could directly modulate the KaiC-作者: headway 時間: 2025-3-23 21:33 作者: grudging 時間: 2025-3-24 01:19 作者: 經(jīng)典 時間: 2025-3-24 06:22 作者: 騷擾 時間: 2025-3-24 08:48
https://doi.org/10.1007/978-3-663-02890-1 detrimental effects on health and have been implicated in metabolic syndrome, gastrointestinal and metabolic diseases, and cancer. In this chapter, we will cover the importance of the bi-directional relationship between circadian rhythms and the intestinal microbiota on host health and disease.作者: 演繹 時間: 2025-3-24 14:02
ights modeling approaches and biotech applications.This book addresses multiple aspects of biological clocks in prokaryotes.. The first part of the book deals with the circadian clock system in cyanobacteria, i.e. the pioneer of bacterial clocks. Starting with the history and background of cyanobact作者: homocysteine 時間: 2025-3-24 15:00
https://doi.org/10.1007/978-3-642-66996-5C 7942 established a model system that ultimately led to the best characterized circadian clockwork at a molecular level. The conclusion of this chapter lists references to the seminal discoveries that have come from the study of cyanobacterial circadian clocks.作者: Ondines-curse 時間: 2025-3-24 23:05
https://doi.org/10.1007/978-3-642-69822-4a-molecular-scale slowness comes from structural regulations of steric hindrance, water molecules, and .-to-. peptide isomerization in KaiC, being related on one-to-one correspondence not only to the frequency of inter-molecular-scale rhythm of KaiA/KaiB/KaiC oscillator, but also to the frequency of cellular-scale rhythms.作者: Bumptious 時間: 2025-3-25 02:48 作者: VOC 時間: 2025-3-25 05:30
Reasons for Seeking Information on the Molecular Structure and Dynamics of Circadian Clock Componenta-molecular-scale slowness comes from structural regulations of steric hindrance, water molecules, and .-to-. peptide isomerization in KaiC, being related on one-to-one correspondence not only to the frequency of inter-molecular-scale rhythm of KaiA/KaiB/KaiC oscillator, but also to the frequency of cellular-scale rhythms.作者: Benign 時間: 2025-3-25 09:49 作者: Demonstrate 時間: 2025-3-25 15:42 作者: placebo 時間: 2025-3-25 16:52
Insights from Mathematical Modeling/Simulations of the In Vitro KaiABC Clockic complexes and protein-protein interactions, and direct numerical simulations of biochemical reactions which incorporate thousands of combinatorial states and their transitions, including the effects of stochasticity (noise) on the simulated dynamics.作者: 審問,審訊 時間: 2025-3-25 22:40
Basic Biology of Rhythms and the Microbiome its environment, and how commensals diurnally modulate host biology in health and disease. Finally, current challenges, open questions, and perspectives in this exciting new field of chronobiology are discussed.作者: Mucosa 時間: 2025-3-26 03:31 作者: 星球的光亮度 時間: 2025-3-26 05:20 作者: FIS 時間: 2025-3-26 11:04 作者: 想象 時間: 2025-3-26 13:03 作者: implore 時間: 2025-3-26 19:09 作者: sorbitol 時間: 2025-3-26 22:48
Zusammenfassung und Schlussfolgerungen,oscillators have not received substantial chronobiological analyses, our findings suggest that the circadian clock can easily transform into a damped oscillator by environmental or genetic perturbation and might function as a semi-clock system.作者: 流浪者 時間: 2025-3-27 02:46
A Retrospective: On Disproving the Transcription–Translation Feedback Loop Model in Cyanobacteriabe recorded by those who remain and is always subject to bias. If this same topic was recalled by, e.g., Takao Kondo, Carl Johnson, or anyone else who was engaged in the same events, it would probably be described completely differently. I would appreciate it if you read this chapter with that perspective in mind.作者: muster 時間: 2025-3-27 08:18
Mechanistic Aspects of the Cyanobacterial Circadian Clock chapter include the following: (1) coordination of moving clock components is achieved through long-range allostery mediated by changes in structure and dynamics such that the clock runs clockwise and not counterclockwise, and (2) the fold-switching behavior of a clock protein underpins circadian rhythms of gene expression.作者: abject 時間: 2025-3-27 10:25
Mechanism of the Cyanobacterial Circadian Clock Protein KaiC to Measure 24 Hoursh has been assumed so far for prokaryotic and eukaryotic organisms. In this chapter, we describe a model for the cyanobacterial circadian clock system that we have derived from our analyses of KaiC ATPase activity.作者: 合同 時間: 2025-3-27 14:23 作者: NOT 時間: 2025-3-27 20:07
Insights into the Evolution of Circadian Clocks Gleaned from Bacterianally, we explain how studying bacteria can generate a greater appreciation and understanding for the?general principles of the?adaptive value of circadian clocks not only towards the daily cycle but also for the seasonal cycle, from both a past and future evolutionary perspective.作者: 車床 時間: 2025-3-28 01:56 作者: RENAL 時間: 2025-3-28 02:37
Book 2021acteria, i.e. the pioneer of bacterial clocks. Starting with the history and background of cyanobacteria and circadian rhythms in microorganisms, the topics range from the molecular basis, structure and evolution of the circadian clock to modelling approaches, Kai systems in cyanobacteria and biotec作者: 鉆孔 時間: 2025-3-28 08:33
The Bacterial Perspective on Circadian Clocks, that dogma and showed that these bacteria could fulfill the criteria for circadian rhythmicity. Development of a luminescence reporter strain of . PCC 7942 established a model system that ultimately led to the best characterized circadian clockwork at a molecular level. The conclusion of this chapt作者: ENACT 時間: 2025-3-28 11:04
Around the Circadian Clock: Review and Previewg’s textbook and Dr. Oota’s lecture on entrainment model of Dr. Pittendrigh’s Drosophila circadian clock. It has been a lot of fun. It took me a long way, but I finally found what I was looking for. My research life can be divided into three periods: the era of duckweed, the era of cyanobacteria, an作者: prodrome 時間: 2025-3-28 17:50
A Retrospective: On Disproving the Transcription–Translation Feedback Loop Model in Cyanobacteria has defied this influential model and set a milestone in chronobiology with the establishment of the in vitro reconstituted oscillator system. As a researcher who had the good fortune to witness this turning point, I would like to review the process from a very personal perspective. I have been str作者: 徹底明白 時間: 2025-3-28 20:20
Mechanistic Aspects of the Cyanobacterial Circadian Clockvariety of mechanisms arose throughout the evolutionary tree as an adaptation to predictable daily swings in ambient light and temperature. In this chapter we will focus exclusively on the circadian clock shared by the cyanobacteria . and ., with a noncomprehensive scope that emphasizes mechanism. A作者: languor 時間: 2025-3-29 00:28
Mechanism of the Cyanobacterial Circadian Clock Protein KaiC to Measure 24 HoursiC shows a circadian rhythm. The major component KaiC is a typical adenosine triphosphatase (ATPase). Although ATPase activity of KaiC is extremely low, the ATPase activity of KaiC by itself shows temperature compensation and correlates with the rate of circadian rhythm (oscillation frequency), indi作者: 苦惱 時間: 2025-3-29 05:57
Oscillation and Input Compensation in the Cyanobacterial Kai Proteinshe phenomenology of this system with a focus on how the Kai oscillator is special compared to generic biochemical oscillators. A key feature is that many external perturbations couple much more strongly to the amplitude than to the period of oscillations. This property is the basis of the ability of作者: 傲慢物 時間: 2025-3-29 11:08 作者: FRET 時間: 2025-3-29 13:44 作者: ingrate 時間: 2025-3-29 18:09 作者: Immunoglobulin 時間: 2025-3-29 22:37 作者: 善變 時間: 2025-3-30 01:32
An In Vitro Approach to Elucidating Clock-Modulating Metabolites turned out to be affected by metabolites that reflect photosynthetic activity. Reconstituting the bacterial timekeeper in a test tube containing only KaiA, KaiB, KaiC, ATP, and magnesium enabled a detailed functional analysis of the circadian clock. Here we added CikA, which competes with KaiA for 作者: dowagers-hump 時間: 2025-3-30 04:50
Damped Oscillation in the Cyanobacterial Clock Systemrial circadian system. First, low temperature transformed the self-sustained KaiC phosphorylation rhythm into damped oscillations. Second, deletion of the . gene showed damped oscillation in the bioluminescent rhythm. These damped rhythms resonated with periodical environmental changes and then reco作者: 摘要 時間: 2025-3-30 08:42
Roles of Phosphorylation of KaiC in the Cyanobacterial Circadian Clockby mixing three clock proteins, KaiA, KaiB, KaiC, and ATP, in which the phosphorylation state of KaiC exhibits robust circadian rhythm. In contrast to eukaryotic clock proteins, sometimes containing tens of phosphorylation sites, KaiC has only two phosphorylation sites, serine 431 and threonine 432,作者: Adenocarcinoma 時間: 2025-3-30 13:36 作者: CLAM 時間: 2025-3-30 20:18
Insights from Mathematical Modeling/Simulations of the In Vitro KaiABC Clockempts by different groups to reproduce various experimental properties of observed clock dynamics. It is separated into a discussion of modeling the dynamics of population phosphoform state transitions to generate limit cycles, and in simulating the dynamics of KaiC hexamers and protein-protein inte作者: 白楊 時間: 2025-3-30 22:30
Basic Biology of Rhythms and the Microbiomeional signals. These diurnal oscillations, in turn, impact the host’s transcriptome and multiple other physiologic functions. Emerging evidence has begun to uncover the molecular mechanisms that underlie the coordinated meta-organismal diurnal rhythmicity with crucial implications for homeostasis an作者: 最后一個 時間: 2025-3-31 01:22
Disease Implications of the Circadian Clocks and Microbiota Interfacevidence has shown that there is an interplay between host circadian rhythms and the gut microbiota. Host circadian rhythm impacts the structure and function of gut microbial community, while in turn the microbiota regulates the host circadian clock and metabolism. Disruption of host rhythms can have作者: 憂傷 時間: 2025-3-31 08:36
Carl Hirschie Johnson,Michael Joseph RustA comprehensive overview on circadian clock systems in prokaryotes.Reviews the circadian clock system in cyanobacteria - including Kai.Highlights modeling approaches and biotech applications作者: 無孔 時間: 2025-3-31 10:45 作者: 不能約 時間: 2025-3-31 17:08 作者: 我吃花盤旋 時間: 2025-3-31 20:52 作者: separate 時間: 2025-3-31 23:25
