標(biāo)題: Titlebook: Cholesterol and PI(4,5)P2 in Vital Biological Functions; From Coexistence to Avia Rosenhouse- Dantsker Book 2023 The Editor(s) (if applica [打印本頁(yè)] 作者: Inveigle 時(shí)間: 2025-3-21 17:24
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書目名稱Cholesterol and PI(4,5)P2 in Vital Biological Functions影響因子(影響力)學(xué)科排名
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書目名稱Cholesterol and PI(4,5)P2 in Vital Biological Functions讀者反饋
書目名稱Cholesterol and PI(4,5)P2 in Vital Biological Functions讀者反饋學(xué)科排名
作者: irradicable 時(shí)間: 2025-3-21 23:02 作者: 滲透 時(shí)間: 2025-3-22 02:29 作者: micronized 時(shí)間: 2025-3-22 05:18 作者: 改變 時(shí)間: 2025-3-22 09:16 作者: 價(jià)值在貶值 時(shí)間: 2025-3-22 15:51 作者: 價(jià)值在貶值 時(shí)間: 2025-3-22 19:44
Regulation of ThermoTRP Channels by PIP2 and Cholesterolre of the ion channel or through indirect mechanisms, which can include modifying membrane properties, such as curvature and rigidity, by regulating their expression or by modulating the actions of other molecules or signaling pathways that affect the physiology of ion channels. Here, we summarize t作者: monogamy 時(shí)間: 2025-3-22 22:24 作者: 預(yù)防注射 時(shí)間: 2025-3-23 03:44 作者: jabber 時(shí)間: 2025-3-23 09:30 作者: 免費(fèi) 時(shí)間: 2025-3-23 09:56 作者: 集中營(yíng) 時(shí)間: 2025-3-23 15:55
Ca2+ and Annexins – Emerging Players for Sensing and Transferring Cholesterol and Phosphoinositides amics but is also critical in autophagy. Cholesterol is highly concentrated at the PM and enriched in recycling endosomes and Golgi membranes. MCS-mediated cholesterol transfer is intensely researched, identifying MCS dysfunction or altered MCS partnerships to correlate with de-regulated cellular ch作者: interference 時(shí)間: 2025-3-23 18:58
Book 2023uces the reader to cholesterol and PI(4,5)P.2.. The second section demonstrates the mutual influence of these two critical lipids on their levels. The third section, divided into two parts, describes the co-modulation of protein function by cholesterol and PI(4,5)P.2.. The first part focuses on ion 作者: 關(guān)心 時(shí)間: 2025-3-23 22:41 作者: 不易燃 時(shí)間: 2025-3-24 04:02
https://doi.org/10.1007/978-3-8349-9776-0 to regulate lysosomal decay of the low-density lipoprotein receptor (LDLR), the primary receptor for hepatic LDL uptake. Section . will discuss how PI(4,5)P. interacts with apolipoprotein A-I (apoA1), the key apolipoprotein on HDL. In addition to direct mechanisms of PI(4,5)P. action on circulating作者: 圣歌 時(shí)間: 2025-3-24 08:20
Zwecke und Konzeptionen der Rechnungslegung,and their role in cholesterol transport. It then continues to describe the modulation of cholesterol efflux in NPC disease. The chapter concludes with a summary of findings related to the functional consequences of perturbations in phosphoinositides in this fatal disease.作者: Lethargic 時(shí)間: 2025-3-24 13:10
Physica-Schriften zur Betriebswirtschaftol in the modulation of the ubiquitously expressed Kir2.1 channel and the synergy between these two lipids in the modulation of the Kir3.4 channel, which is primarily expressed in the heart. Additionally, we demonstrate that there is also synergy in the modulation of Kir3.2 channels, which are expre作者: dragon 時(shí)間: 2025-3-24 15:48 作者: 解脫 時(shí)間: 2025-3-24 21:02
https://doi.org/10.1007/978-3-322-96478-6nding sites. This modular structure suggested that PI(4,5)P2 and calcium cooperate to maintain the conductive state in TMEM16A. Cholesterol, the second-largest constituent of the plasma membrane, also regulates TMEM16A though the mechanism, functional outcomes, binding site(s), and effects on TMEM16作者: crockery 時(shí)間: 2025-3-25 01:58 作者: athlete’s-foot 時(shí)間: 2025-3-25 04:44
Joachim K?lschbach,Stefan Engel?nderrol removal from artery plaques, via an athero-protective reverse cholesterol transport (RCT) pathway, can dampen inflammation. Phosphatidylinositol 4,5-bisphosphate (PIP2) plays a role in RCT by promoting adenosine triphosphate (ATP)-binding cassette transporter A1 (ABCA1)-mediated cholesterol effl作者: Palate 時(shí)間: 2025-3-25 10:06 作者: TIGER 時(shí)間: 2025-3-25 15:40 作者: 儀式 時(shí)間: 2025-3-25 18:19
Book 2023the most abundant membrane phosphoinositide. Both lipids play key roles in a variety of cellular functions including as signalling molecules and major regulators of protein function. Studies on these important lipids have traditionally focused on the effect of each lipid individually. Accumulating e作者: ciliary-body 時(shí)間: 2025-3-25 21:58 作者: AGGER 時(shí)間: 2025-3-26 02:45 作者: 憤憤不平 時(shí)間: 2025-3-26 04:23 作者: 主動(dòng)脈 時(shí)間: 2025-3-26 11:39
Role of Lysosomal Cholesterol in Regulating PI(4,5)P2-Dependent Ion Channel Functionr will introduce the biosynthetic pathways of cholesterol and PI(4,5)P., discuss the molecular mechanisms through which each lipid distinctly regulates ion channels, and consider the interdependence of these lipids in the control of ion channel function.作者: instill 時(shí)間: 2025-3-26 13:19
0065-2598 merging relationship between cholesterol and PI(4,5).Discuss.Cholesterol is an essential component of the plasma membrane. Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P.2.), although a minor phospholipid, is the most abundant membrane phosphoinositide. Both lipids play key roles in a variety of ce作者: 甜得發(fā)膩 時(shí)間: 2025-3-26 17:50
Zwecke und Konzeptionen der Rechnungslegung,ding rigidity of lipid membranes. Fundamental structure–property relations of molecular self-assembly are illuminated and point toward a length and time-scale dependence of cell membrane mechanics, with significant implications for biological activity and membrane lipid–protein interactions.作者: entail 時(shí)間: 2025-3-26 22:16
,Eigenkapitalver?nderungsrechnung,ing of positively charged residues (Arg., Lys., Lys.) immediately after S6, respectively. A model that could explain the modulation of BK. activity by cholesterol and/or PIP. is hypothesized. The roles of additional sites, whether in slo1 or BK. regulatory subunits, for PIP. and/or cholesterol to modulate BK. function are also discussed.作者: 慌張 時(shí)間: 2025-3-27 01:45
https://doi.org/10.1007/978-3-322-91148-3e unique role of phosphoinositides (PPIns), and phosphatidylinositol 4-phosphate (PI4P) in particular, for the control of non-vesicular Chol transport. In this chapter, we will review the emerging connection between Chol, PPIns, and lipid transfer proteins that include the important family of oxysterol-binding protein related proteins, or ORPs.作者: 充足 時(shí)間: 2025-3-27 07:53 作者: 畏縮 時(shí)間: 2025-3-27 12:58
Cholesterol and PIP2 Modulation of BKCa Channelsing of positively charged residues (Arg., Lys., Lys.) immediately after S6, respectively. A model that could explain the modulation of BK. activity by cholesterol and/or PIP. is hypothesized. The roles of additional sites, whether in slo1 or BK. regulatory subunits, for PIP. and/or cholesterol to modulate BK. function are also discussed.作者: Genome 時(shí)間: 2025-3-27 16:54
Roles of Phosphatidylinositol 4-Phosphorylation in Non-vesicular Cholesterol Traffickinge unique role of phosphoinositides (PPIns), and phosphatidylinositol 4-phosphate (PI4P) in particular, for the control of non-vesicular Chol transport. In this chapter, we will review the emerging connection between Chol, PPIns, and lipid transfer proteins that include the important family of oxysterol-binding protein related proteins, or ORPs.作者: Indebted 時(shí)間: 2025-3-27 20:33
https://doi.org/10.1007/978-3-8349-9776-0ma membrane (PM). Both lipids play key roles in a variety of cellular functions including as signaling molecules and major regulators of protein function. This chapter provides an overview of these two important lipids. Starting from a brief description of their structure, synthesis, and regulation,作者: 改進(jìn) 時(shí)間: 2025-3-28 01:13 作者: Retrieval 時(shí)間: 2025-3-28 05:17 作者: 痛苦一下 時(shí)間: 2025-3-28 09:46 作者: 厚顏 時(shí)間: 2025-3-28 11:57 作者: Allege 時(shí)間: 2025-3-28 17:41 作者: 休戰(zhàn) 時(shí)間: 2025-3-28 22:36
https://doi.org/10.1007/978-3-642-99764-8 of functions include the regulation of cell growth, gene regulation, metabolic signaling, cell migration, and cell death. In this chapter, we detail how another of the lysosome’s crucial roles, cholesterol transport, plays a vital role in the control of ion channel function and neuronal excitabilit作者: opprobrious 時(shí)間: 2025-3-29 00:30 作者: Engaging 時(shí)間: 2025-3-29 05:58
Anne Schurbohm-Ebneth,Hans Liecke channels are polymodal and are activated by several stimuli. Among TRPs, some members of this family of channels respond to changes in ambient temperature and are known as thermoTRPs. These proteins respond to heat or cold in the noxious range and some of them to temperatures considered innocuous,作者: 不透明 時(shí)間: 2025-3-29 10:21
https://doi.org/10.1007/978-3-322-96478-6, fluid and electrolyte secretion, pain sensation, sensory transduction, and neuronal and muscle excitability. Their gating depends on the voltage-dependent binding of two intracellular calcium ions to a high-affinity site formed by acidic residues from α-helices 6–8 in each monomer. Phosphatidylino作者: 粗魯性質(zhì) 時(shí)間: 2025-3-29 12:48
,Eigenkapitalver?nderungsrechnung,gulatory mechanisms in the entire organism. One process mediating calcium signaling involves hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P.) by the phospholipase-C (PLC). Thus, calcium and PtdIns(4,5)P. are intimately intertwined two second-messenger cascades that often depend on作者: 弄污 時(shí)間: 2025-3-29 16:53
https://doi.org/10.1007/978-3-322-91148-3brane proteins. Chol is synthesized in the ER, but it is selectively enriched within the plasma membrane (PM) and other endomembranes, which requires Chol to cross the aqueous phase of the cytoplasm. In addition to the classical vesicular trafficking pathways that are known to facilitate the bulk tr作者: 廚師 時(shí)間: 2025-3-29 21:17 作者: 搖晃 時(shí)間: 2025-3-30 02:51
https://doi.org/10.1007/9978-3-8349-9433-2racellular medium. To circumvent the hydrophobic barrier formed by the acyl chains of the lipid bilayer, protein channels and transporters are key players in the exchange of small hydrophilic compounds such as ions or nutrients, but they hardly account for the transport of larger biological molecule作者: Blasphemy 時(shí)間: 2025-3-30 05:29
https://doi.org/10.1007/9978-3-8349-9433-2ynthesized in the endoplasmic reticulum (ER) and require delivery to other organelles. In this scenario, formation of membrane contact sites (MCS) between neighbouring organelles has emerged as a novel non-vesicular lipid transport mechanism. Dissecting the molecular composition of MCS identified ph作者: Foregery 時(shí)間: 2025-3-30 12:17 作者: 尾巴 時(shí)間: 2025-3-30 16:06 作者: comely 時(shí)間: 2025-3-30 16:56 作者: 飛行員 時(shí)間: 2025-3-30 23:53 作者: CREST 時(shí)間: 2025-3-31 03:10
Cholesterol and PI(4,5)P2 in Vital Biological Functions978-3-031-21547-6Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: Countermand 時(shí)間: 2025-3-31 05:07
PI(4,5)P2 and Cholesterol: Synthesis, Regulation, and Functionsma membrane (PM). Both lipids play key roles in a variety of cellular functions including as signaling molecules and major regulators of protein function. This chapter provides an overview of these two important lipids. Starting from a brief description of their structure, synthesis, and regulation,作者: libertine 時(shí)間: 2025-3-31 11:35 作者: 鍍金 時(shí)間: 2025-3-31 15:57
