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標(biāo)題: Titlebook: Cholesterol Transporters of the START Domain Protein Family in Health and Disease; START Proteins - Str Barbara J. Clark,Douglas‘M. Stocco [打印本頁]

作者: HBA1C    時(shí)間: 2025-3-21 19:51
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作者: Infect    時(shí)間: 2025-3-22 00:04
The Steroidogenic Acute Regulatory Protein (StAR),al and gonads following tropic hormone stimulation. StAR synthesis is required for the first and rate-limiting step in steroid hormone biosynthesis, cholesterol transport into mitochondria. It was a long journey to finding the acute regulator of steroidogenesis, and this chapter provides a historica
作者: 噴油井    時(shí)間: 2025-3-22 04:17

作者: 是限制    時(shí)間: 2025-3-22 06:35

作者: Gleason-score    時(shí)間: 2025-3-22 11:43

作者: 領(lǐng)帶    時(shí)間: 2025-3-22 16:25

作者: 領(lǐng)帶    時(shí)間: 2025-3-22 21:02

作者: 大門在匯總    時(shí)間: 2025-3-22 21:39

作者: GIBE    時(shí)間: 2025-3-23 02:10
Book 2014es directed at soluble cholesterol transport proteins indicate that aberrant expression of the START proteins may contribute to disease states associated with disorders in cholesterol homeostasis. This is an exciting new direction in the field and the purpose of this book will be to highlight the cu
作者: 大雨    時(shí)間: 2025-3-23 08:24

作者: 背信    時(shí)間: 2025-3-23 13:23
,Abkürzungen, Bezeichnungen und Symbole, led to our current understanding of the cyclic adenosine-3′,5′-monophosphate (cAMP)-protein kinase A-dependent mechanisms that control StAR expression at the transcriptional and post-transcriptional levels in steroidogenic tissues.
作者: Explosive    時(shí)間: 2025-3-23 17:06
The Steroidogenic Acute Regulatory Protein (StAR), led to our current understanding of the cyclic adenosine-3′,5′-monophosphate (cAMP)-protein kinase A-dependent mechanisms that control StAR expression at the transcriptional and post-transcriptional levels in steroidogenic tissues.
作者: 財(cái)主    時(shí)間: 2025-3-23 19:37

作者: 切掉    時(shí)間: 2025-3-24 01:36
An Introduction to the Steroidogenic Acute Regulatory Protein (StAR)-Related Lipid Transfer Domain n START family members, e.g., STARD1, STARD11, and STARD2 are well characterized for their roles in cholesterol, ceramide, and phosphatidylcholine transfer, respectively, while much remains to be learned about the remaining family members. The purpose of this book is to present a compendium of the h
作者: Canyon    時(shí)間: 2025-3-24 04:02
START Domain Protein Structure and Ligand Specificity,RD11) binding have conserved residues that play a structural role in the formation of a cavity that fits the shape of their specific ligands. We also expose a correlation between structural fluctuations reported to occur in secondary and tertiary structure elements of START domains and we suggest co
作者: anthropologist    時(shí)間: 2025-3-24 10:23

作者: altruism    時(shí)間: 2025-3-24 11:50
Steroidogenic Acute Regulatory Protein (StAR) and Atherogenesis,fflux process mediated by adenosine triphosphate (ATP)-binding cassette transporters (ABCA1/G1) and apolipoprotein acceptors, and inhibits nuclear factor-κB signalling, resulting in repression of an array of inflammatory genes. Thus, StAR/STARD1 may represent a novel target for treatment of atherosc
作者: 來自于    時(shí)間: 2025-3-24 15:30
STARD3: A Lipid Transfer Protein in Breast Cancer and Cholesterol Trafficking,main spanning the amino-terminal half of the protein that we named the MLN64-N-terminal (MENTAL) domain. This domain contains most of the functional properties that have been attributed to STARD3. This chapter will present our current understanding of STARD3 function in cancer, cell biology, and cho
作者: allergy    時(shí)間: 2025-3-24 22:31

作者: 縮減了    時(shí)間: 2025-3-24 23:40

作者: 連系    時(shí)間: 2025-3-25 06:20

作者: 調(diào)味品    時(shí)間: 2025-3-25 08:24
Cholesterol Transporters of the START Domain Protein Family in Health and Disease978-1-4939-1112-7
作者: nurture    時(shí)間: 2025-3-25 13:39

作者: triptans    時(shí)間: 2025-3-25 18:27
,Abkürzungen, Bezeichnungen und Symbole,n START family members, e.g., STARD1, STARD11, and STARD2 are well characterized for their roles in cholesterol, ceramide, and phosphatidylcholine transfer, respectively, while much remains to be learned about the remaining family members. The purpose of this book is to present a compendium of the h
作者: Contend    時(shí)間: 2025-3-25 23:33
https://doi.org/10.1007/978-3-642-81608-6RD11) binding have conserved residues that play a structural role in the formation of a cavity that fits the shape of their specific ligands. We also expose a correlation between structural fluctuations reported to occur in secondary and tertiary structure elements of START domains and we suggest co
作者: Vital-Signs    時(shí)間: 2025-3-26 00:15
,Hydrostatische Anlagen — Stand der Technik,of its action remains unclear. Lipoid CAH is caused by StAR mutations and is thus the StAR knockout experiment of nature. Recent work has shown that P450scc mutations cause a disease that is a phenocopy of lipoid CAH. The discovery of StAR led to the discovery of the broader family of structurally r
作者: Deadpan    時(shí)間: 2025-3-26 08:12
https://doi.org/10.1007/978-3-642-81608-6fflux process mediated by adenosine triphosphate (ATP)-binding cassette transporters (ABCA1/G1) and apolipoprotein acceptors, and inhibits nuclear factor-κB signalling, resulting in repression of an array of inflammatory genes. Thus, StAR/STARD1 may represent a novel target for treatment of atherosc
作者: euphoria    時(shí)間: 2025-3-26 10:42

作者: inquisitive    時(shí)間: 2025-3-26 13:41
Struktursynthese hydrostatischer Anlagen,loosely with specific subcellular membranes. (4) STARD4 can bind cholesterol and efficiently transfer it between membranes. (5) STARD4 can mediate transfer of cholesterol to the ER resident enzyme acyl-coenzyme A cholesterol acyltransferase (ACAT) for esterification. (6) STARD5 does not have these A
作者: Neuropeptides    時(shí)間: 2025-3-26 18:36

作者: 頭盔    時(shí)間: 2025-3-27 00:27

作者: 原告    時(shí)間: 2025-3-27 03:37
,Abkürzungen, Bezeichnungen und Symbole,al and gonads following tropic hormone stimulation. StAR synthesis is required for the first and rate-limiting step in steroid hormone biosynthesis, cholesterol transport into mitochondria. It was a long journey to finding the acute regulator of steroidogenesis, and this chapter provides a historica
作者: 磨碎    時(shí)間: 2025-3-27 06:46
https://doi.org/10.1007/978-3-642-81608-6ids that binds a broad variety of lipids and sterols. START domain proteins have various expression patterns and cellular localizations and are involved in lipid metabolism, lipid transfer, and cell signalling. The α-helix/β-grip tertiary structure delimits an internal cavity forming the binding sit
作者: Frequency-Range    時(shí)間: 2025-3-27 13:30
,Hydrostatische Anlagen — Stand der Technik,chanisms by which cholesterol is delivered to cellular destinations remains under investigation. Steroidogenic cells must transport large amounts of cholesterol to, and then into, the mitochondria, where the cholesterol side-chain cleavage enzyme, P450scc, resides. P450scc is the first enzyme in ste
作者: Rheumatologist    時(shí)間: 2025-3-27 16:49

作者: Iniquitous    時(shí)間: 2025-3-27 17:57

作者: 2否定    時(shí)間: 2025-3-27 22:47
Struktursynthese hydrostatischer Anlagen,which share ~?30?% amino acid identity with each other, ~?20?% with the StAR/STARD1 and STARD3/metastatic lymph node clone 64 (MLN64) START domains, and ~?15?% with other START domains. All three have no other protein domains besides START. Since their initial discovery, they were proposed to serve
作者: escalate    時(shí)間: 2025-3-28 04:59
https://doi.org/10.1007/978-3-642-81608-6o maintain the proper sterol and lipid distribution. The steroidogenic acute regulatory protein-related lipid transfer (START) domain family are defined by a conserved 210 amino acid sequence that folds into an α/β helix-grip structure containing a hydrophobic pocket for ligand binding. The mammalia
作者: 原諒    時(shí)間: 2025-3-28 07:49

作者: 背帶    時(shí)間: 2025-3-28 11:40

作者: 脫水    時(shí)間: 2025-3-28 14:38
https://doi.org/10.1007/978-1-4939-1112-7cholesterol homeostasis; cholesterol transport; endocrinology; start transporters
作者: GORGE    時(shí)間: 2025-3-28 20:56
978-1-4939-5403-2Springer Science+Business Media New York 2014




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