標(biāo)題: Titlebook: Cholesterol Transport Systems and Their Relation to Atherosclerosis; Armin Steinmetz,Hans Kaffarnik,Jürgen Schneider Conference proceeding [打印本頁(yè)] 作者: Spouse 時(shí)間: 2025-3-21 19:53
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis影響因子(影響力)
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis影響因子(影響力)學(xué)科排名
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis網(wǎng)絡(luò)公開度
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis被引頻次
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis被引頻次學(xué)科排名
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis年度引用
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis年度引用學(xué)科排名
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis讀者反饋
書目名稱Cholesterol Transport Systems and Their Relation to Atherosclerosis讀者反饋學(xué)科排名
作者: 爭(zhēng)吵 時(shí)間: 2025-3-21 22:40 作者: 貞潔 時(shí)間: 2025-3-22 04:03
https://doi.org/10.1007/978-3-642-75092-2 experimentally to manipulate the proportion of molecules degraded or recycled [5, 6]. With the fundamental properties of receptor-mediated endocytosis in mind, we examined the HDL pathway using as the ligands HDL and an apo A-I containing hybrid protein constructed using recombinant DNA techniques.作者: 飛來(lái)飛去真休 時(shí)間: 2025-3-22 06:40 作者: happiness 時(shí)間: 2025-3-22 10:05
An Apo A-I Protein A Hybrid Used for the Study of HDL Receptor Binding and Endocytosis experimentally to manipulate the proportion of molecules degraded or recycled [5, 6]. With the fundamental properties of receptor-mediated endocytosis in mind, we examined the HDL pathway using as the ligands HDL and an apo A-I containing hybrid protein constructed using recombinant DNA techniques.作者: 小隔間 時(shí)間: 2025-3-22 13:13 作者: 小隔間 時(shí)間: 2025-3-22 20:16 作者: Excitotoxin 時(shí)間: 2025-3-22 21:31
Regulation of Macrophage Cholesterol HomeostasisThe occurence of receptor defects [1] or structural defects of apolipoproteins [2] prevent a normal lipoprotein-receptor interaction. The abnormal lipoprotein particles thus formed are enriched with cholesteryl esters and are catabolized via a separate, so-called scavenger pathway in the macrophage system.作者: 現(xiàn)暈光 時(shí)間: 2025-3-23 04:51 作者: 致敬 時(shí)間: 2025-3-23 05:39 作者: 魅力 時(shí)間: 2025-3-23 12:22 作者: 與野獸博斗者 時(shí)間: 2025-3-23 16:18
Conference proceedings 1989 E polymorphism in cholesterol homeostasis. The combination of general outline form and very specific aspects of cholesterol transport will interest those in other disciplines following developments in the field, as well as those directly involved in lipoprotein research.作者: GULP 時(shí)間: 2025-3-23 18:57 作者: 寬容 時(shí)間: 2025-3-24 00:42 作者: CUMB 時(shí)間: 2025-3-24 03:04 作者: 歡呼 時(shí)間: 2025-3-24 10:10 作者: meritorious 時(shí)間: 2025-3-24 12:30
https://doi.org/10.1007/978-3-642-82074-8sma lipoproteins may also bind to the extracellular matrix of the arterial wall. Both processes are dependent on the concentration of lipoproteins in the intima, which is influenced by the plasma lipoprotein level, the permeability of the lining of endothelial cells, and blood pressure.作者: 大氣層 時(shí)間: 2025-3-24 15:29
https://doi.org/10.1007/978-3-642-75092-2CAT), an enzyme which catalyzes the esterification of free cholesterol, and, secondly, plasma lipid transfer protein(s) (LTPs), which are involved in the exchange and transfer of CE, triacylglycerols (TG), and phospholipids between the lipoproteins.作者: Project 時(shí)間: 2025-3-24 21:01
1431-7567 sk factors for the development of atherosclerosis and coronary heart disease. This volume examines the state of the art of lipoprotein subclass metabolism and its relation to these diseases. The authors also report on new developments concerning the role of lipoprotein recptors, macrophages and apol作者: 極少 時(shí)間: 2025-3-25 01:39
,Gestalt?nderung technischer Gebilde,e. These polymorphisms can be used as neutral markers to genotype individuals and to follow the inheritance of the LDL receptor gene in families. About 80% of individuals are heterozygous for at least one of these RFLPs, and they are therefore potentially informative for DNA diagnosis.作者: In-Situ 時(shí)間: 2025-3-25 03:32
https://doi.org/10.1007/978-3-322-87681-2oth observations led to the implication that lipid peroxides may play a dual role in atherogenesis [5]. Thus, the influx of LDL into the aortic wall and its oxidative modification by the aortic cells may be important in early atherogenesis.作者: 使隔離 時(shí)間: 2025-3-25 09:29 作者: CURL 時(shí)間: 2025-3-25 12:24 作者: Popcorn 時(shí)間: 2025-3-25 16:13
Situation der Arbeitsplatzgestaltung,d/or low-density lipoproteins (LDL). Since the initial description of FCHL, many investigators have noted the occurrence of multiple lipoprotein phenotypes in single families, usually those in which there is a high frequency of premature vascular complications.作者: 全國(guó)性 時(shí)間: 2025-3-25 20:43 作者: Texture 時(shí)間: 2025-3-26 02:37
Verfahrensbeschreibung Tiefziehen,Different immunological methods are available to measure these particles and consist in evaluation of apo A-I not associated with apo A-II containing lipoproteins immunoaffinity chromatography [4, 5], gel electroimmunodiffusion [6], immunoprecipitation in free solution [2], and enzyme-linked immunosorbent assay [7].作者: Pedagogy 時(shí)間: 2025-3-26 06:44 作者: dominant 時(shí)間: 2025-3-26 09:54 作者: 食物 時(shí)間: 2025-3-26 15:46
Lipoproteins and Atherosclerosis: Lessons from an Animal Model for Familial Hypercholesterolemiamber of hepatic LDL receptors decreases due to dietary factors such as casein [6], cholesterol [7], or animal fats [8], the serum level of cholesterol (LDL cholesterol) increases in experimental animals or even in the normal population [2], and atherosclerosis develops.作者: byline 時(shí)間: 2025-3-26 17:44
Antiatherogenic Effect of Apolipoprotein A-I Containing LipoproteinsDifferent immunological methods are available to measure these particles and consist in evaluation of apo A-I not associated with apo A-II containing lipoproteins immunoaffinity chromatography [4, 5], gel electroimmunodiffusion [6], immunoprecipitation in free solution [2], and enzyme-linked immunosorbent assay [7].作者: GLEAN 時(shí)間: 2025-3-26 23:32
Role of Apolipoprotein A-IV in Reverse Cholesterol Transportis of apo A-IV, the intestinal induction of this apoprotein has been studied in more detail. In primary cultures of nonproliferating rat hepatocytes dexamethasone and insulin increased apo A-IV mRNA substantially and could be shown to act synergistically when applied simultaneously [13].作者: 形容詞 時(shí)間: 2025-3-27 02:34
https://doi.org/10.1007/978-3-662-09700-7 and specific amphipathic proteins (see [1] for review). The latter, the apolipoproteins, not only are responsible for maintaining the structure of the particle but also act as recognition signals for cell membrane receptors which trigger lipoprotein endocytosis [2]. The “classical” lipoprotein rece作者: Brochure 時(shí)間: 2025-3-27 08:56
Analyse der Automatisierungsaufgabe,abolized by a complex process that is regulated by a number of different factors [1]. These include the assembly and secretion of triglyceride-rich apo B containing lipoprotein particles, intravascular lipolysis of the triglycerides, exchange of lipids and proteins between lipoprotein particles, and作者: tackle 時(shí)間: 2025-3-27 13:14
https://doi.org/10.1007/978-3-642-52219-2 lipoproteins which are then internalized by the cells. Insofar as lipoprotein receptors affect the concentration of lipoproteins in the plasma and may play a role in lipoprotein accumulation in arterial cells, they have both a direct and an indirect influence on the progression of atherosclerosis. 作者: palette 時(shí)間: 2025-3-27 15:55
Situation der Arbeitsplatzgestaltung,FCHL) was first used by Joseph Goldstein and associates at the University of Washington to designate families exhibiting multiple lipoprotein phenotypes. At the same time, similar families were described by Esko Nikkil? in Helsinki and Herbert Rose in New York. Affected members of families with FCHL作者: 符合你規(guī)定 時(shí)間: 2025-3-27 20:52
Hans-Friedrich Peters,Rudolf Kollerurveys conducted in many countries over the past 30 years have uniformly shown that atherosclerosis becomes more severe as the mean level of low-density lipoprotein (LDL) cholesterol rises in a population [2, 3]. Especially in patients with familial hypercholesterolemia (FH), there are elevations of作者: Adherent 時(shí)間: 2025-3-27 22:09
,Gestalt?nderung technischer Gebilde,ata in some cases, and increased risk of myocardial infarction [5]. The genetic basis of FH was analysed by Brown and Goldstein et al. in 1983, who demonstrated that FH is caused by mutation in the LDL receptor gene, and that the defective gene is inherited as an autosomal dominant disorder [6]. The作者: BIPED 時(shí)間: 2025-3-28 02:33
https://doi.org/10.1007/978-3-642-81905-6 to be associated with a specific lipoprotein fraction that is now commonly termed Lp(a) (for recent review see [2]). This lipoprotein has pre-β-mobility on zone electrophoresis as opposed to the β-mobility of LDL, and it has a higher hydrated density of 1.06–1.12 g/ml.作者: 運(yùn)動(dòng)性 時(shí)間: 2025-3-28 06:25 作者: 進(jìn)入 時(shí)間: 2025-3-28 13:48
https://doi.org/10.1007/978-3-322-87681-2e early atherosclerotic lesion [1]. Monocytes/macrophages invade the aortic wall through an intact endothelial layer early after induction of a hypercholesterolemic state in humans and various experimental animal systems [2–4]. The underlying mechanisms stimulating the cell migration are still unkno作者: 行乞 時(shí)間: 2025-3-28 15:16
https://doi.org/10.1007/978-3-322-87681-2vel must either decrease the rate of LDL formation or speed up the rate of its clearance from the plasma. The latter can be effected by increasing the specific LDL (or apo B, E) receptor activity in the liver, as is actually brought about by administration of bile acid sequestrants [3] and/or compac作者: Conserve 時(shí)間: 2025-3-28 20:36 作者: Pageant 時(shí)間: 2025-3-28 23:30
Verfahrensbeschreibung Tiefziehen,own that half of apo A-I is associated with apo A-II while the rest occurs in lipoproteins which contain no apo A-II [1, 2]. These two types of lipoprotein particles, present in vivo, were described by numerous authors and have been suggested to represent metabolically distinct entities [1–6]. Both 作者: FELON 時(shí)間: 2025-3-29 06:30 作者: 惡意 時(shí)間: 2025-3-29 10:23
https://doi.org/10.1007/978-3-642-75092-2ir capacity to donate cholesteryl ester (CE) to other lipoproteins [1]. These two processes are fundamental to the uptake of cholesterol by tissues and to the removal of cholesterol from tissues. Various plasma proteins are involved in these processes firstly, lecithin cholesterol acyltransferase (L作者: 雀斑 時(shí)間: 2025-3-29 12:57 作者: lymphoma 時(shí)間: 2025-3-29 17:33
Cholesterol Transport Systems and Their Relation to Atherosclerosis978-3-642-83665-7Series ISSN 1431-7567 作者: paleolithic 時(shí)間: 2025-3-29 20:48 作者: 過(guò)分 時(shí)間: 2025-3-30 03:29
https://doi.org/10.1007/978-3-322-87681-2vel must either decrease the rate of LDL formation or speed up the rate of its clearance from the plasma. The latter can be effected by increasing the specific LDL (or apo B, E) receptor activity in the liver, as is actually brought about by administration of bile acid sequestrants [3] and/or compactin or mevinolin [4].作者: 后天習(xí)得 時(shí)間: 2025-3-30 06:40
https://doi.org/10.1007/978-3-642-83665-7Lipoprotein; atherosclerosis; heart; high-density lipoprotein (HDL); homeostasis; metabolism; protein; meta作者: HILAR 時(shí)間: 2025-3-30 09:40 作者: 輕觸 時(shí)間: 2025-3-30 14:52 作者: 防止 時(shí)間: 2025-3-30 19:50 作者: 颶風(fēng) 時(shí)間: 2025-3-31 00:02
Removal of Low-Density Lipoproteins by Alternative Pathwaysvel must either decrease the rate of LDL formation or speed up the rate of its clearance from the plasma. The latter can be effected by increasing the specific LDL (or apo B, E) receptor activity in the liver, as is actually brought about by administration of bile acid sequestrants [3] and/or compactin or mevinolin [4].作者: 出處 時(shí)間: 2025-3-31 01:25
Receptors in the Regulation of Cholesterol Metabolism and specific amphipathic proteins (see [1] for review). The latter, the apolipoproteins, not only are responsible for maintaining the structure of the particle but also act as recognition signals for cell membrane receptors which trigger lipoprotein endocytosis [2]. The “classical” lipoprotein rece
