標(biāo)題: Titlebook: Centromeres and Kinetochores; Discovering the Mole Ben E. Black Book 2017 Springer International Publishing AG 2017 centomeres.kinetochores [打印本頁(yè)] 作者: 熱愛(ài) 時(shí)間: 2025-3-21 20:03
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作者: Missile 時(shí)間: 2025-3-22 00:09 作者: meritorious 時(shí)間: 2025-3-22 01:36
The Power of , Egg Extract for Reconstitution of Centromere and Kinetochore Functiontro reconstitution studies are beginning to uncover how the kinetochore is assembled upon the underlying centromere, how the kinetochore couples chromosome movement to microtubule dynamics, and how cells ensure the site of kinetochore assembly is maintained from one generation to the next. Here we g作者: 百科全書 時(shí)間: 2025-3-22 06:46
Centrochromatin of Fungile microtubules during chromosome segregation. Research over the last decades demonstrated that centromeres are defined by a combination of genetic and epigenetic factors. Recent work showed that centromeres are quite diverse and flexible and that many types of centromere sequences and centromeric c作者: GLEAN 時(shí)間: 2025-3-22 12:05
Evolutionary Lessons from Species with Unique Kinetochoresnt to spindle microtubules. Kinetochore research over the last several decades has been focused on a few animal and fungal model organisms, which revealed a detailed understanding of the composition and organization of their kinetochores. Yet, these traditional model organisms represent only a small作者: 手榴彈 時(shí)間: 2025-3-22 16:20
Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to t of a strong self-templating epigenetic mechanism that renders centromeres heritable. We review how specific quantitative microscopy approaches have contributed to the determination of the copy number, architecture, size, and dynamics of centromeric chromatin and its associated centromere complex a作者: 手榴彈 時(shí)間: 2025-3-22 20:34
Orchestrating the Specific Assembly of Centromeric Nucleosomescanonical histone H3 variant is replaced by Centromere Protein A (CENP-A). Therefore, the assembly and propagation of centromeric nucleosomes are critical for maintaining centromere identify and ensuring genomic stability. Centromeres direct chromosome segregation (during mitosis and meiosis) by rec作者: ADJ 時(shí)間: 2025-3-22 23:30 作者: DEAF 時(shí)間: 2025-3-23 04:42 作者: GET 時(shí)間: 2025-3-23 05:53
Centromere Silencing Mechanismses as the site of centromere formation and kinetochore assembly. Decades of research have defined the DNA sequence and protein components of functional centromeres, and the interdependencies of specific protein complexes for proper centromere assembly. Less is known about how centromeres are disasse作者: deface 時(shí)間: 2025-3-23 11:54
Centromere Transcription: ,d for centromere identity, assembly and stable transgenerational inheritance. Research over the past 20?years has challenged the classical descriptions of a centromere as a stable, unmutable, and transcriptionally silent chromosome component. Instead, based on studies from a broad range of eukaryoti作者: 秘傳 時(shí)間: 2025-3-23 16:44
The Promises and Challenges of Genomic Studies of Human Centromeresthough the biological importance of centromeres in genome stability, and ultimately, cell viability are well understood, the complete sequence content and organization in these multi-megabase-sized regions remains unknown. The lack of a high-resolution reference assembly inhibits standard bioinforma作者: Density 時(shí)間: 2025-3-23 20:34 作者: 祖?zhèn)髫?cái)產(chǎn) 時(shí)間: 2025-3-23 23:37 作者: 乞討 時(shí)間: 2025-3-24 05:15
Centromere Dynamics in Male and Female Germ Cellsthat divide asymmetrically to generate gonial pre-cursors, which are amplified in number by mitotic divisions, undergo meiosis and eventually differentiate into mature gametes (haploid eggs and sperm). Information transmitted with gametes is inherited by offspring, and potentially by subsequent gene作者: PHON 時(shí)間: 2025-3-24 10:07
Centromeres and Kinetochores978-3-319-58592-5Series ISSN 0079-6484 Series E-ISSN 2197-8484 作者: 經(jīng)典 時(shí)間: 2025-3-24 12:36 作者: BIDE 時(shí)間: 2025-3-24 17:48 作者: 填滿 時(shí)間: 2025-3-24 21:06
https://doi.org/10.1007/978-3-319-58592-5centomeres; kinetochores; chromatin; chromosome segregation; epigenetics; mitosis; Cell Cycle Analysis作者: 死貓他燒焦 時(shí)間: 2025-3-25 00:03 作者: 來(lái)就得意 時(shí)間: 2025-3-25 04:36 作者: 矛盾 時(shí)間: 2025-3-25 10:02 作者: persistence 時(shí)間: 2025-3-25 13:47
Umweltschutz und Ziele der Unternehmungtro reconstitution studies are beginning to uncover how the kinetochore is assembled upon the underlying centromere, how the kinetochore couples chromosome movement to microtubule dynamics, and how cells ensure the site of kinetochore assembly is maintained from one generation to the next. Here we g作者: Abbreviate 時(shí)間: 2025-3-25 17:34
Umweltschutz und Ziele der Unternehmungle microtubules during chromosome segregation. Research over the last decades demonstrated that centromeres are defined by a combination of genetic and epigenetic factors. Recent work showed that centromeres are quite diverse and flexible and that many types of centromere sequences and centromeric c作者: 散開 時(shí)間: 2025-3-25 21:34
Umweltbezogene Unternehmungsstrategiennt to spindle microtubules. Kinetochore research over the last several decades has been focused on a few animal and fungal model organisms, which revealed a detailed understanding of the composition and organization of their kinetochores. Yet, these traditional model organisms represent only a small作者: 發(fā)炎 時(shí)間: 2025-3-26 03:32 作者: 鉆孔 時(shí)間: 2025-3-26 06:45 作者: 沙文主義 時(shí)間: 2025-3-26 09:17 作者: GENRE 時(shí)間: 2025-3-26 13:32
The Analysis of Spatial Orientation, in diverse diseases. Covalent post-translational modifications of histones are a prominent way to regulate chromatin structure and different chromatin regions bear their specific signature of histone modifications. The composition of centromeric chromatin is significantly different from other chrom作者: 大量殺死 時(shí)間: 2025-3-26 18:16 作者: Sinus-Node 時(shí)間: 2025-3-26 23:01 作者: EPT 時(shí)間: 2025-3-27 02:17 作者: SNEER 時(shí)間: 2025-3-27 05:45 作者: 造反,叛亂 時(shí)間: 2025-3-27 12:41 作者: misshapen 時(shí)間: 2025-3-27 13:54
Organisation der Forschungsuniversit?tthat divide asymmetrically to generate gonial pre-cursors, which are amplified in number by mitotic divisions, undergo meiosis and eventually differentiate into mature gametes (haploid eggs and sperm). Information transmitted with gametes is inherited by offspring, and potentially by subsequent gene作者: 上下連貫 時(shí)間: 2025-3-27 19:02 作者: chemical-peel 時(shí)間: 2025-3-27 22:04
https://doi.org/10.1007/978-3-642-99771-6expression cloning methods, which allowed antibodies to lead to cDNA clones. Next, functional screens for kinetochore proteins were made possible by the isolation of yeast centromeric DNAs. Ultimately, the completion of genome sequences for humans and model organisms permitted the coupling of bioche作者: Cupping 時(shí)間: 2025-3-28 02:24 作者: Flatter 時(shí)間: 2025-3-28 06:47
Umweltbezogene Unternehmungsstrategienlar localization of kinetochores has changed from the nucleoplasm to the nuclear membrane. Finally, we speculate on the organization of the chromosome segregation machinery in an early eukaryotic ancestor to gain insights into fundamental principles of the chromosome segregation machinery, which are作者: 實(shí)現(xiàn) 時(shí)間: 2025-3-28 10:35
Kerstin Cuhls,Terutaka Kuwaharaly in early G1, into pre-existing chromatin, and several additional chromatin-associated complexes regulate CENP-A nucleosome deposition and stability. Here we review the current knowledge on how new CENP-A nucleosomes are assembled selectively at the existing centromere in different species and how作者: 豪華 時(shí)間: 2025-3-28 16:17 作者: addict 時(shí)間: 2025-3-28 21:59 作者: NOCT 時(shí)間: 2025-3-29 00:52
https://doi.org/10.1007/978-3-658-00133-9y and function. To illustrate the transcriptional landscape of centromeres across eukaryotes, we focus this review on how transcripts interact with centromere proteins, when in the cell cycle centromeric transcription occurs, and what types of sequences are being transcribed. Utilizing data from bro作者: 低能兒 時(shí)間: 2025-3-29 05:56 作者: Gnrh670 時(shí)間: 2025-3-29 10:39 作者: 得罪人 時(shí)間: 2025-3-29 13:39
Use of Mass Spectrometry to Study the Centromere and Kinetochoreexpression cloning methods, which allowed antibodies to lead to cDNA clones. Next, functional screens for kinetochore proteins were made possible by the isolation of yeast centromeric DNAs. Ultimately, the completion of genome sequences for humans and model organisms permitted the coupling of bioche作者: MEAN 時(shí)間: 2025-3-29 15:55
Centrochromatin of Fungiment options against fungal infection, and biotechnologies based on fungi. This review summarizes the current knowledge of fungal centromeres and centrochromatin, including an outlook for future research.作者: 特別容易碎 時(shí)間: 2025-3-29 23:21
Evolutionary Lessons from Species with Unique Kinetochoreslar localization of kinetochores has changed from the nucleoplasm to the nuclear membrane. Finally, we speculate on the organization of the chromosome segregation machinery in an early eukaryotic ancestor to gain insights into fundamental principles of the chromosome segregation machinery, which are作者: 心胸狹窄 時(shí)間: 2025-3-30 02:44 作者: deactivate 時(shí)間: 2025-3-30 07:46
Artificial Chromosomes and Strategies to Initiate Epigenetic Centromere Establishmentenome to dissect the role of many centromere-associated proteins and chromatin modifiers for centromere inheritance and function. Together, these studies showed that chromatin context matters, particularly proximity to heterochromatin or repetitive DNA sequences. Moreover, despite the important cont作者: Peristalsis 時(shí)間: 2025-3-30 10:09 作者: thyroid-hormone 時(shí)間: 2025-3-30 15:29 作者: 噱頭 時(shí)間: 2025-3-30 19:32
The Unique DNA Sequences Underlying Equine Centromerese-less configuration of centromeres is common in this group which has undergone particularly rapid karyotype evolution. These features have established the equids as a new mammalian system in which to investigate the molecular organization, dynamics and evolutionary behaviour of centromeres.作者: CODA 時(shí)間: 2025-3-30 21:12
Centromere Dynamics in Male and Female Germ Cellslogous chromosomes (at leptotene and zygotene), crossing-over (at pachytene), and the appearance of chiasmata (at diplotene/diakinesis). Another unique feature of meiosis is the altered centromere/kinetochore geometry at metaphase I, such that sister kinetochores face the same spindle pole (mono-ori