作者: magenta 時間: 2025-3-21 21:09
Primary Immunodeficiencies,Primary immunodeficiency diseases (PID) are a part of the growing field of inborn errors of immunity (IEI), sharing a raised susceptibility to infectious diseases and often associated to other features such as autoimmunity, autoinflammation, and lymphoproliferation and susceptibility to neoplastic disease and atopic diseases.作者: Irremediable 時間: 2025-3-22 03:28
Mario Milco D‘Elios,Cosima Tatiana Baldari,FrancesFeatures updated management and all the latest genetic sof cellular primary immunodeficiencies.Offers in-depth description of the basis of cellular immune responses.Valued companion to immunologists, 作者: 沒有希望 時間: 2025-3-22 06:25 作者: lanugo 時間: 2025-3-22 11:23 作者: 出生 時間: 2025-3-22 15:01 作者: 出生 時間: 2025-3-22 17:28
https://doi.org/10.1007/978-3-540-49761-5pecific MHC-associated antigen, T lymphocytes assemble a highly organized intercellular junction, referred to as the immune synapse, on which T cell activation, proliferation, and differentiation crucially depend. Immune synapse assembly and function are impaired in a subgroup of human immunodeficie作者: 拍翅 時間: 2025-3-22 22:51
https://doi.org/10.1007/978-3-540-49761-5anical and chemical means, they prevent invasion by pathogens. The mucosal immune system consists of an innate and acquired system that interact with each other in a complex way. The mucosal immune system also has the delicate task of differentiating between pathogens and non-pathogens. The T and B 作者: 地牢 時間: 2025-3-23 04:26 作者: Counteract 時間: 2025-3-23 07:31
Equipment, Instruments, and Materials,nogenic defects affecting phagocyte numbers and/or function have been described. A common hallmark of all congenital defects of phagocytes is an increased susceptibility to severe bacterial and fungal infections. Typical sites of infection are the skin, the oral mucosa and gingiva, lymph nodes, the 作者: 微塵 時間: 2025-3-23 11:46
Surgical Extraction of Impacted Teeth,mponents of innate immunity, not included in phagocyte defects or complement defects. It is a very diverse group of primary immunodeficiencies (PID) or inborn errors of immunity (IEI), both immunologically and clinically, but all share that (1) microbial susceptibility is usually very selective and 作者: 發(fā)牢騷 時間: 2025-3-23 14:04
Superconductivity and Superfluidity,, autoimmunity, and increased susceptibility to infections. They are caused by defects in genes involved in controlling when and how the immune system must turn on, which and how much cytokines release, which antigens should be eliminated and which neglected, and why and when the immune response has作者: follicle 時間: 2025-3-23 19:38
https://doi.org/10.1007/978-3-540-68008-6iagnosis techniques have deeply implemented the identification of new monogenic defects leading to an altered immune homeostasis. Regulatory T cells (Tregs) play an essential role in controlling immune response, and mutations affecting the transcription factor FOXP3 cause immune dysregulation, polye作者: Monolithic 時間: 2025-3-23 22:13 作者: 潰爛 時間: 2025-3-24 06:01
On Superconductivity and Superfluiditynment to a continuous contact with air and with the external world. Lung epithelium and lung connective tissue are protected by an articulated and pervasive immune system, which fights the external microbial and toxic threats while preserving respiratory function and blood oxygenation. The balance b作者: 擋泥板 時間: 2025-3-24 06:54 作者: 基因組 時間: 2025-3-24 13:13 作者: 巧辦法 時間: 2025-3-24 15:14
Needles, Sutures, and Instruments,missions is represented by primary immunodeficiencies (PID) and autoimmunity (AI), respectively. As such, PID and AI could be simplistically thought as mutually exclusive..However, over 25% of patients with PID present one or more autoimmune disease with organ- or non-organ-specific manifestations, 作者: Junction 時間: 2025-3-24 20:45 作者: Generic-Drug 時間: 2025-3-25 00:36
Principles of Vocal Fold Augmentation cell and/or B cell dysfunction. Hematopoietic stem cell transplantation (HSCT) represents a curative treatment in certain patients with cellular immunodeficiency; enzyme replacement therapy and gene therapy may be further options in very specific settings. Apart from disease-specific treatments, an作者: Pastry 時間: 2025-3-25 03:40
Operative Techniques in Laryngologyby vaccines is among the most effective healthcare measures mainly for these subjects. As in humoral immune deficiencies, . specific . be deepened. Firstly, response to vaccine is often seriously compromised in patients affected by cellular immunodeficiencies so that some vaccines result inefficacio作者: 槍支 時間: 2025-3-25 10:08
Operative Techniques in LaryngologyloHSCT). However, while this therapy is curative for many PIDs, the procedure requires a suitably matched donor and carries significant risks of morbidity and mortality from complications such as graft-versus-host disease (GVHD). Autologous gene therapy (GT) approaches using stem cells isolated from作者: 斷言 時間: 2025-3-25 12:07
Phenocopies of Primary Immunodeficiency Diseases,er, they are caused by somatic mutations or autoantibodies against cytokines rather than germline monogenic defects. They are classified as a separate group by the International Union of Immunological Societies (IUIS).作者: Chameleon 時間: 2025-3-25 18:05 作者: Feigned 時間: 2025-3-25 21:45
Cellular Primary Immunodeficiencies978-3-030-70107-9Series ISSN 2282-6505 Series E-ISSN 2283-6403 作者: Firefly 時間: 2025-3-26 01:16
https://doi.org/10.1007/978-3-540-49761-5er, they are caused by somatic mutations or autoantibodies against cytokines rather than germline monogenic defects. They are classified as a separate group by the International Union of Immunological Societies (IUIS).作者: 不適當 時間: 2025-3-26 07:54 作者: 牢騷 時間: 2025-3-26 11:44 作者: dandruff 時間: 2025-3-26 14:08
978-3-030-70109-3Springer Nature Switzerland AG 2021作者: CRASS 時間: 2025-3-26 19:21
Book 2021s; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth d作者: intrude 時間: 2025-3-26 21:44 作者: ineptitude 時間: 2025-3-27 04:34
https://doi.org/10.1007/978-3-540-49761-5ic responses, such as local IgA secretion. In this chapter, we will discuss in a non-exhaustive way the main components and mechanisms of innate and adaptive mucosal immunity and how this can be compromised in primary immunodeficiencies.作者: 防御 時間: 2025-3-27 09:17
Superconductivity and Superfluidity,n antigens, and finally to and/or hyperinflammation that damage cells and organs. The treatment of these disorders is often challenging, as it often requires immunosuppression in the presence of increased risk of infections.作者: 兩種語言 時間: 2025-3-27 12:06
Dysfunctional Immune Synapses in T Cell Immunodeficiencies,e immune synapse and describe how dysfunctional immune synapses can impinge on the pathogenesis of T cell immunodeficiencies, highlighting the reciprocal contribution of alterations at either side of the IS.作者: forthy 時間: 2025-3-27 16:58
Mucosal Immunity in Primary Immunodeficiencies,ic responses, such as local IgA secretion. In this chapter, we will discuss in a non-exhaustive way the main components and mechanisms of innate and adaptive mucosal immunity and how this can be compromised in primary immunodeficiencies.作者: 一加就噴出 時間: 2025-3-27 17:53
Diseases of Immune Dysregulation,n antigens, and finally to and/or hyperinflammation that damage cells and organs. The treatment of these disorders is often challenging, as it often requires immunosuppression in the presence of increased risk of infections.作者: vitrectomy 時間: 2025-3-28 00:47
Book 2021lular Primary Immunodeficiencies?.?will be of?high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students..作者: 軟膏 時間: 2025-3-28 04:32 作者: Arthr- 時間: 2025-3-28 06:28 作者: packet 時間: 2025-3-28 12:10
On Superconductivity and Superfluidityd lung complications (see Table .); lung complications (see Table .) in PID can be broadly divided in infections and chronic complications. In this chapter, we review the main clinical and epidemiological features associated with lung involvement in PID.作者: BLAND 時間: 2025-3-28 15:23
Needles, Sutures, and Instruments,estations associated with PID categorized as (i) SCID/CID, (ii) LOCID, (iii) APECED, (iv) IPEX, (v) hypogammaglobulinemias, (vi) immunodysregulation disorders, and (vii) ALPS, describing each prototypical molecular defect and delving into the mechanisms that contribute to the development of AI.作者: BINGE 時間: 2025-3-28 19:39 作者: travail 時間: 2025-3-29 02:55
IPEX Syndrome and IPEX-Related Disorders,gs biology or Tregs unrelated, and acting at different levels during immune response regulation. The clinical similarities and differences between these inborn errors of immunity, along with their molecular cause, diagnosis, and treatment options, will be discussed.作者: 自負的人 時間: 2025-3-29 05:17
Lung in Cellular Immunodeficiencies,d lung complications (see Table .); lung complications (see Table .) in PID can be broadly divided in infections and chronic complications. In this chapter, we review the main clinical and epidemiological features associated with lung involvement in PID.作者: 蔓藤圖飾 時間: 2025-3-29 07:33
Autoimmunity in Cellular Immunodeficiencies,estations associated with PID categorized as (i) SCID/CID, (ii) LOCID, (iii) APECED, (iv) IPEX, (v) hypogammaglobulinemias, (vi) immunodysregulation disorders, and (vii) ALPS, describing each prototypical molecular defect and delving into the mechanisms that contribute to the development of AI.作者: constellation 時間: 2025-3-29 12:56 作者: 清楚 時間: 2025-3-29 17:14 作者: 商業(yè)上 時間: 2025-3-29 19:58
Phenocopies of Primary Immunodeficiency Diseases,er, they are caused by somatic mutations or autoantibodies against cytokines rather than germline monogenic defects. They are classified as a separate group by the International Union of Immunological Societies (IUIS).作者: 軍火 時間: 2025-3-29 23:55
Dysfunctional Immune Synapses in T Cell Immunodeficiencies,pecific MHC-associated antigen, T lymphocytes assemble a highly organized intercellular junction, referred to as the immune synapse, on which T cell activation, proliferation, and differentiation crucially depend. Immune synapse assembly and function are impaired in a subgroup of human immunodeficie作者: 屈尊 時間: 2025-3-30 06:58
Mucosal Immunity in Primary Immunodeficiencies,anical and chemical means, they prevent invasion by pathogens. The mucosal immune system consists of an innate and acquired system that interact with each other in a complex way. The mucosal immune system also has the delicate task of differentiating between pathogens and non-pathogens. The T and B 作者: geriatrician 時間: 2025-3-30 11:42
Combined Immunodeficiencies, due to several genetic variants. In contrast to severe combined immunodeficiencies (SCID), CID are typically milder diseases and can have a delayed onset. Patients with CID may present with recurrent, often severe, viral, bacterial, mycobacterial, fungal, and protozoan infections, mainly affecting 作者: 貿(mào)易 時間: 2025-3-30 15:35 作者: gorgeous 時間: 2025-3-30 17:07
Defects in Intrinsic and Innate Immunity,mponents of innate immunity, not included in phagocyte defects or complement defects. It is a very diverse group of primary immunodeficiencies (PID) or inborn errors of immunity (IEI), both immunologically and clinically, but all share that (1) microbial susceptibility is usually very selective and 作者: collagenase 時間: 2025-3-31 00:19
Diseases of Immune Dysregulation,, autoimmunity, and increased susceptibility to infections. They are caused by defects in genes involved in controlling when and how the immune system must turn on, which and how much cytokines release, which antigens should be eliminated and which neglected, and why and when the immune response has作者: 收到 時間: 2025-3-31 01:07 作者: 權(quán)宜之計 時間: 2025-3-31 05:15 作者: Handedness 時間: 2025-3-31 10:12
Lung in Cellular Immunodeficiencies,nment to a continuous contact with air and with the external world. Lung epithelium and lung connective tissue are protected by an articulated and pervasive immune system, which fights the external microbial and toxic threats while preserving respiratory function and blood oxygenation. The balance b作者: Retrieval 時間: 2025-3-31 13:28 作者: chandel 時間: 2025-3-31 19:23
Malignancies in Cellular Immunodeficiencies, which is a predisposition to severe, unusual or recurrent infections. In addition, there are frequently accompanying features of immune dysregulation and an increased risk of hematopoietic and other malignancies. Although several forms of PID are associated with an increased risk of malignancy, thi作者: Alopecia-Areata 時間: 2025-4-1 00:51 作者: Cholecystokinin 時間: 2025-4-1 04:52 作者: mettlesome 時間: 2025-4-1 09:04
Management of Cellular Immunodeficiencies, cell and/or B cell dysfunction. Hematopoietic stem cell transplantation (HSCT) represents a curative treatment in certain patients with cellular immunodeficiency; enzyme replacement therapy and gene therapy may be further options in very specific settings. Apart from disease-specific treatments, an作者: 商談 時間: 2025-4-1 10:25
Vaccines in Cellular Immunodeficiencies,by vaccines is among the most effective healthcare measures mainly for these subjects. As in humoral immune deficiencies, . specific . be deepened. Firstly, response to vaccine is often seriously compromised in patients affected by cellular immunodeficiencies so that some vaccines result inefficacio作者: 有發(fā)明天才 時間: 2025-4-1 15:31
Gene Therapy in Cellular Immunodeficiencies,loHSCT). However, while this therapy is curative for many PIDs, the procedure requires a suitably matched donor and carries significant risks of morbidity and mortality from complications such as graft-versus-host disease (GVHD). Autologous gene therapy (GT) approaches using stem cells isolated from作者: Postulate 時間: 2025-4-1 20:05
2282-6505 rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students..978-3-030-70109-3978-3-030-70107-9Series ISSN 2282-6505 Series E-ISSN 2283-6403
