標(biāo)題: Titlebook: Cardiac Energy Metabolism in Health and Disease; Gary D. Lopaschuk,Naranjan S. Dhalla Book 2014 Springer Science+Business Media New York 2 [打印本頁] 作者: ARGOT 時間: 2025-3-21 19:18
書目名稱Cardiac Energy Metabolism in Health and Disease影響因子(影響力)
書目名稱Cardiac Energy Metabolism in Health and Disease影響因子(影響力)學(xué)科排名
書目名稱Cardiac Energy Metabolism in Health and Disease網(wǎng)絡(luò)公開度
書目名稱Cardiac Energy Metabolism in Health and Disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cardiac Energy Metabolism in Health and Disease被引頻次
書目名稱Cardiac Energy Metabolism in Health and Disease被引頻次學(xué)科排名
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書目名稱Cardiac Energy Metabolism in Health and Disease讀者反饋
書目名稱Cardiac Energy Metabolism in Health and Disease讀者反饋學(xué)科排名
作者: arrhythmic 時間: 2025-3-21 23:08
Lipoproteins: A Source of Cardiac Lipidshesized in the liver and they obtain their mature form following interaction with enzymes that are present in the circulation. Lipoprotein-derived fatty acids are released by lipoprotein lipase and are then taken up by cardiomyocytes either passively or via fatty acid receptors, such as CD36. Uptake作者: JUST 時間: 2025-3-22 01:28
Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heartnagement predisposes the patient to heart failure, which is the leading cause of diabetes related deaths. One instigator for this cardiac dysfunction is change in fuel utilization by the heart. Thus, following diabetes, when cardiac glucose utilization is impaired, the heart undergoes metabolic tran作者: 業(yè)余愛好者 時間: 2025-3-22 04:36
Control of Myocardial Fatty Acid Uptakel carbohydrate (glucose, lactate) uptake have been unraveled in detail in the 1990s, insight into fatty acid uptake originates from more recent studies. Fatty acid movement across the sarcolemma is facilitated by membrane-associated proteins, specifically CD36, membrane-associated fatty acid-binding作者: flimsy 時間: 2025-3-22 12:23 作者: 泥沼 時間: 2025-3-22 12:52 作者: 泥沼 時間: 2025-3-22 18:31
Relationship Between Substrate Metabolism and Cardiac Efficiencysm with efficient ATP generation and utilization. As ATP is primarily derived from mitochondrial oxidative phosphorylation, myocardial oxygen consumption (MVO.) can be used to measure the rate of energy expenditure of the heart. Although cardiac efficiency is an ambiguous term, it commonly embraces 作者: 不自然 時間: 2025-3-23 00:05 作者: certitude 時間: 2025-3-23 01:29 作者: 帶來的感覺 時間: 2025-3-23 07:34
The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heartnd energy utilising ATPases. It acts as an energy storage and transport mechanism and maintains favourable local ATP/ADP ratios, thereby supporting further energy production and high levels of free energy from ATP hydrolysis. Down-regulation of CK activity and myocardial creatine levels is a univers作者: 延期 時間: 2025-3-23 12:47
Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failurevelopment of pathological cardiac hypertrophy, a significant remodeling of metabolic pathways leads to a disruption in energy homeostasis, which contributes to the eventual heart failure. These changes include a shift of substrate preference from fatty acids to glucose, a reduction in the overall ox作者: Urea508 時間: 2025-3-23 16:27 作者: THROB 時間: 2025-3-23 20:11
The Role of AMPK in the Control of Cardiac Hypertrophyat can have profound detrimental consequences. AMP-activated protein kinase (AMPK), a well-studied mediator of cellular energy homeostasis, has been shown to be a regulator of cardiac hypertrophy via its influence on several key signaling pathways involved in cardiomyocyte growth control. Although t作者: 善于 時間: 2025-3-24 01:20 作者: micturition 時間: 2025-3-24 06:05
Metabolic Therapy for the Ischemic Heart flow limiting coronary stenosis is the main recognized pathological mechanism underlying this condition. While revascularization procedures are performed with the aim to remove the flow limiting stenosis, traditional medical therapy with hemodynamic agents aim at reducing oxygen demand of the myoca作者: 綁架 時間: 2025-3-24 07:37
Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patientsaltered in heart failure and has been considered a contributing factor in the impaired heart function observed in patients with heart failure. Emerging evidence demonstrates that correcting these changes in energy metabolism by modulating mitochondrial oxidative metabolism may be effective treatment作者: 因無茶而冷淡 時間: 2025-3-24 14:19 作者: narcissism 時間: 2025-3-24 18:03 作者: membrane 時間: 2025-3-24 21:11 作者: 大溝 時間: 2025-3-25 02:48 作者: 脫毛 時間: 2025-3-25 05:56 作者: 制定法律 時間: 2025-3-25 11:25 作者: 問到了燒瓶 時間: 2025-3-25 12:59 作者: 聯(lián)邦 時間: 2025-3-25 16:51
Nonparametric Functional Data Analysisnagement predisposes the patient to heart failure, which is the leading cause of diabetes related deaths. One instigator for this cardiac dysfunction is change in fuel utilization by the heart. Thus, following diabetes, when cardiac glucose utilization is impaired, the heart undergoes metabolic tran作者: ALOFT 時間: 2025-3-25 23:25
https://doi.org/10.1007/0-387-36620-2l carbohydrate (glucose, lactate) uptake have been unraveled in detail in the 1990s, insight into fatty acid uptake originates from more recent studies. Fatty acid movement across the sarcolemma is facilitated by membrane-associated proteins, specifically CD36, membrane-associated fatty acid-binding作者: 法律 時間: 2025-3-26 01:23
Small Ball Probabilities and Semi-metricsresult in dramatic alterations in cardiac energy metabolism, which can contribute to the progression of heart failure. Elevated rates of fatty acid oxidation and depressed rates of glucose oxidation characterize the cardiac metabolic profile in the setting of obesity-induced insulin resistance and d作者: Exterior 時間: 2025-3-26 07:55
Local Weighting of Functional Variablesthat a complex network of nuclear transcription factors is essential for the coordinated regulation of mitochondrial biogenesis, maturation and function. These transcription factors guide developmental changes in mitochondrial number, structure, and dynamics as well as respond to various physiologic作者: VEIL 時間: 2025-3-26 10:47
Nonparametric Functional Data Analysissm with efficient ATP generation and utilization. As ATP is primarily derived from mitochondrial oxidative phosphorylation, myocardial oxygen consumption (MVO.) can be used to measure the rate of energy expenditure of the heart. Although cardiac efficiency is an ambiguous term, it commonly embraces 作者: seroma 時間: 2025-3-26 14:12
https://doi.org/10.1007/0-387-36620-2 function. Non-enzymatic and enzymatic mechanisms appear to function in facilitating this modification of protein lysine residues. The functional role of protein acetylation was originally linked to lifespan regulation in simple organisms under the control of sirtuin deacetylase enzymes. In higher o作者: 南極 時間: 2025-3-26 17:47 作者: 變態(tài) 時間: 2025-3-26 21:43 作者: antiandrogen 時間: 2025-3-27 01:52
Nonparametric Functional Data Analysisvelopment of pathological cardiac hypertrophy, a significant remodeling of metabolic pathways leads to a disruption in energy homeostasis, which contributes to the eventual heart failure. These changes include a shift of substrate preference from fatty acids to glucose, a reduction in the overall ox作者: 你敢命令 時間: 2025-3-27 07:06 作者: 泄露 時間: 2025-3-27 12:45 作者: 失望未來 時間: 2025-3-27 17:11
Miklós Cs?rg?,Lajos Horváth,Paul Deheuvelsits associated dyslipidemia negatively affect the myocardium and lead to cardiac dysfunction. Current dogma suggests that obesity-associated dyslipidemia increases fatty acid delivery to the heart, which contributes to both excessive fatty acid uptake and subsequent fatty acid oxidation rates that u作者: Brocas-Area 時間: 2025-3-27 18:53 作者: 去掉 時間: 2025-3-28 00:47 作者: 洞穴 時間: 2025-3-28 02:57 作者: FUSE 時間: 2025-3-28 07:57
Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heartprotein lipase (LPL), the enzyme responsible for providing fat to the hearts. Either exaggeration or reduction in its activity following diabetes could lead to heart dysfunction. The objective of this article is to describe the biology of LPL during diabetes. By gaining more insight into the mechani作者: NOTCH 時間: 2025-3-28 14:26
Control of Myocardial Fatty Acid Uptakeof the intracellular cycling of CD36 underlies various cardiac metabolic diseases. As a result, the mechanism and regulation of myocardial glucose uptake by GLUT4 cycling and of fatty acid uptake by CD36 cycling are very similar. Likely, manipulation of the presence and/or activity of substrate tran作者: 緩解 時間: 2025-3-28 17:58
Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetesterventions that prevent or reverse the energy metabolic switch in the heart of obese and diabetic individuals, and/or the accumulation of fatty acid metabolites may lessen the severity of heart failure. These interventions include inhibiting myocardial fatty acid oxidation, stimulating glucose oxid作者: ALT 時間: 2025-3-28 18:46 作者: 大廳 時間: 2025-3-29 00:49
Relationship Between Substrate Metabolism and Cardiac Efficiencythe beneficial effect of metabolic therapies may also relate to improvement of cardiac efficiency. The focus in this chapter will therefore be on our current understanding of how myocardial substrate supply and/or utilization contribute to altered cardiac efficiency.作者: 開始發(fā)作 時間: 2025-3-29 06:03 作者: Commentary 時間: 2025-3-29 07:17
The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Hearty, however, recent evidence suggests that loss of creatine or CK is not detrimental in surgical models of chronic heart failure, providing the clearest evidence to date that such changes do not contribute to dysfunction. Despite this conclusion, over-expression of CK in mouse heart has been found to作者: 譏諷 時間: 2025-3-29 12:38 作者: 排名真古怪 時間: 2025-3-29 17:30 作者: laceration 時間: 2025-3-29 21:22
Metabolic Therapy for the Ischemic Heartch from one substrate to another according to substrate availability, nutritional status, and exercise level. Paradoxically, during prolonged and severe ischemia the myocardium continues to derive most of its energy (50–70 %) from β-oxidation, despite a high rate of lactate production. At this stage作者: Ventricle 時間: 2025-3-30 03:09 作者: Pageant 時間: 2025-3-30 06:41
Nonparametric Functional Data Analysisprotein lipase (LPL), the enzyme responsible for providing fat to the hearts. Either exaggeration or reduction in its activity following diabetes could lead to heart dysfunction. The objective of this article is to describe the biology of LPL during diabetes. By gaining more insight into the mechani作者: relieve 時間: 2025-3-30 11:08
https://doi.org/10.1007/0-387-36620-2of the intracellular cycling of CD36 underlies various cardiac metabolic diseases. As a result, the mechanism and regulation of myocardial glucose uptake by GLUT4 cycling and of fatty acid uptake by CD36 cycling are very similar. Likely, manipulation of the presence and/or activity of substrate tran作者: hieroglyphic 時間: 2025-3-30 12:39 作者: Pessary 時間: 2025-3-30 18:39
Local Weighting of Functional Variablesummarizes our current understanding of the perturbations in the gene regulatory pathways that occur during the development of heart failure. An appreciation of the role this regulatory circuitry serves in the regulation of cardiac energy metabolism may guide the development of novel therapeutic targ作者: 彎曲的人 時間: 2025-3-31 00:10 作者: 反饋 時間: 2025-3-31 01:30 作者: arthroscopy 時間: 2025-3-31 08:17 作者: 按等級 時間: 2025-3-31 09:53
Nonparametric Functional Data Analysisanelles with high concentrations of Ca.. These observations support the view that mitochondrial dysfunction with respect to energy production due to I/R injury, occurs as a result of oxidative stress and intracellular Ca.-overload. It is also evident that mitochondrial alterations in the I/R hearts 作者: PSA-velocity 時間: 2025-3-31 16:14 作者: 愚笨 時間: 2025-3-31 19:27
Ricardo Fraiman,Gonzalo Perez Iribarrench from one substrate to another according to substrate availability, nutritional status, and exercise level. Paradoxically, during prolonged and severe ischemia the myocardium continues to derive most of its energy (50–70 %) from β-oxidation, despite a high rate of lactate production. At this stage
