標(biāo)題: Titlebook: Cardiac Drug Development Guide; Michael K. Pugsley Book 2003 Springer Science+Business Media New York 2003 [打印本頁(yè)] 作者: purulent 時(shí)間: 2025-3-21 16:12
書目名稱Cardiac Drug Development Guide影響因子(影響力)
書目名稱Cardiac Drug Development Guide影響因子(影響力)學(xué)科排名
書目名稱Cardiac Drug Development Guide網(wǎng)絡(luò)公開度
書目名稱Cardiac Drug Development Guide網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Cardiac Drug Development Guide被引頻次
書目名稱Cardiac Drug Development Guide被引頻次學(xué)科排名
書目名稱Cardiac Drug Development Guide年度引用
書目名稱Cardiac Drug Development Guide年度引用學(xué)科排名
書目名稱Cardiac Drug Development Guide讀者反饋
書目名稱Cardiac Drug Development Guide讀者反饋學(xué)科排名
作者: 小丑 時(shí)間: 2025-3-21 22:51
J. Brindley,A. V. Holden,A. PalmerMAPKs found in cardiac tissue include the extracellular signal-regulated kinases (ERKs), the stress-activated/c-Jun NH2-terminal kinases (SAPK/JNKs), p38-MAPK, and ERK5/big MAPK 1 (BMK1). The ERKs are strongly activated by mitogenic and growth factors and by physical stress, SAPK/JNKs and p38-MAPK c作者: PSA-velocity 時(shí)間: 2025-3-22 03:55
V. S. Letokhov,A. A. Makarov,E. A. Ryabov function, providing additional targets for drug development. However, clinical experience has shown that the therapeutic index for the existing potent platelet inhibitors is narrow, suggesting that new and novel approaches to impairing platelet function will be required.作者: photopsia 時(shí)間: 2025-3-22 06:23
V. S. Letokhov,A. A. Makarov,E. A. Ryabovdominance of NHE-1 in the myocardium is of some importance because pharmacological development of NHE inhibitors for cardiac therapeutics has concentrated specifically on those agents that are selective for NHE-1. These agents, as well as the earlier nonspecific amiloride derivatives have now been e作者: Preserve 時(shí)間: 2025-3-22 11:16 作者: BILE 時(shí)間: 2025-3-22 15:20
The Role of Cardiac Pacemaker Currents in Antiarrhythmic Drug Discoveryas been a subject of much puzzlement. By the 1970s, it was clear that to provide a slow depolarization, there must be a slow increase in net inward current, although it was not clear whether this came about as a consequence of the slow inactivation of an outward current (presumed to be a carried by 作者: BILE 時(shí)間: 2025-3-22 18:32 作者: Water-Brash 時(shí)間: 2025-3-22 21:29 作者: 行為 時(shí)間: 2025-3-23 03:41
The Sodium-Hydrogen Exchange System in the Heartdominance of NHE-1 in the myocardium is of some importance because pharmacological development of NHE inhibitors for cardiac therapeutics has concentrated specifically on those agents that are selective for NHE-1. These agents, as well as the earlier nonspecific amiloride derivatives have now been e作者: canonical 時(shí)間: 2025-3-23 08:26 作者: GUILT 時(shí)間: 2025-3-23 13:16
1557-2153 This book introduces topics in an easily understandable format for researchers in many varying disciplines by integrating and thereby simplifying concepts not usually discussed across a broad r978-1-4899-3828-2978-1-59259-404-7Series ISSN 1557-2153 Series E-ISSN 1940-6053 作者: MEN 時(shí)間: 2025-3-23 14:10 作者: 真繁榮 時(shí)間: 2025-3-23 19:45 作者: Cytology 時(shí)間: 2025-3-23 22:12 作者: Reverie 時(shí)間: 2025-3-24 05:06
Nonlinear Wave Processes in Excitable Media leakage from terminal oxidation and other enzymatic processes even under physiological conditions. Free radicals have unpaired electrons on their outer orbit, which makes these short-lived molecular fragments highly reactive with biomolecules, such as lipids, proteins, nucleic acids, and carbohydra作者: 不足的東西 時(shí)間: 2025-3-24 08:07
J. Brindley,A. V. Holden,A. Palmertems participating in the transduction of signal from the cell membrane to nuclear and other intracellular targets is the highly conserved mitogen-activated protein kinase (MAPK) superfamily. The members of MAPK family are involved in the regulation of a large variety of cellular processes, such as 作者: PANIC 時(shí)間: 2025-3-24 12:43
Quantum Localization of Dynamic Chaos before the age of 60, resulting in health expenditures of over $100 billion per year. Even though cardiovascular disease primarily affects people advanced in age, disease progression begins early. Initiation of atherogenesis via formation of fatty streaks can occur as early as infancy (.).作者: 背信 時(shí)間: 2025-3-24 17:47
V. S. Letokhov,A. A. Makarov,E. A. Ryabovdisease (.). Although considerable effort has been expended to associate augmented platelet function with arterial thrombosis, it is more likely that the formation of platelet thrombi simply represents normal platelet function in the wrong location. It follows then that a rational approach to treati作者: 愛哭 時(shí)間: 2025-3-24 21:45
V. S. Letokhov,A. A. Makarov,E. A. Ryabovns. There is now excellent evidence that stimulation of NHE contributes to paradoxical induction of cell injury. The mechanism for this is related to the fact that activation of the exchanger is closely coupled to sodium influx and, therefore, to elevation in intracellular calcium concentrations thr作者: 減弱不好 時(shí)間: 2025-3-25 00:25 作者: gait-cycle 時(shí)間: 2025-3-25 05:57 作者: itinerary 時(shí)間: 2025-3-25 09:01 作者: 比目魚 時(shí)間: 2025-3-25 15:15
Development of Anti-Inflammatory Drugs for Cardiovascular Disease before the age of 60, resulting in health expenditures of over $100 billion per year. Even though cardiovascular disease primarily affects people advanced in age, disease progression begins early. Initiation of atherogenesis via formation of fatty streaks can occur as early as infancy (.).作者: 墊子 時(shí)間: 2025-3-25 15:48
Michael K. PugsleyIncludes supplementary material: 作者: Affectation 時(shí)間: 2025-3-25 20:41 作者: 澄清 時(shí)間: 2025-3-26 02:40
Cardiac Drug Development Guide978-1-59259-404-7Series ISSN 1557-2153 Series E-ISSN 1940-6053 作者: Anticoagulant 時(shí)間: 2025-3-26 05:33
https://doi.org/10.1007/978-3-662-55725-90 US deaths per year, or nearly one-quarter of all cardiovascular-related deaths (.). The majority of such deaths, which have remained at a nearly constant ratio since the 1970s when cardiac drug development programs were formally being established within the pharmaceutical industry, are caused by ventricular fibrillation (VF; .).作者: 洞穴 時(shí)間: 2025-3-26 10:24
Quantum Localization of Dynamic Chaos before the age of 60, resulting in health expenditures of over $100 billion per year. Even though cardiovascular disease primarily affects people advanced in age, disease progression begins early. Initiation of atherogenesis via formation of fatty streaks can occur as early as infancy (.).作者: climax 時(shí)間: 2025-3-26 15:53
Cardiac Drug Development0 US deaths per year, or nearly one-quarter of all cardiovascular-related deaths (.). The majority of such deaths, which have remained at a nearly constant ratio since the 1970s when cardiac drug development programs were formally being established within the pharmaceutical industry, are caused by v作者: IOTA 時(shí)間: 2025-3-26 18:18 作者: Anthropoid 時(shí)間: 2025-3-27 00:11 作者: 直言不諱 時(shí)間: 2025-3-27 03:42
Mitogen-Activated Protein Kinases-Mediated Signaling in Cardiac Pathologytems participating in the transduction of signal from the cell membrane to nuclear and other intracellular targets is the highly conserved mitogen-activated protein kinase (MAPK) superfamily. The members of MAPK family are involved in the regulation of a large variety of cellular processes, such as 作者: Obituary 時(shí)間: 2025-3-27 09:13 作者: 火光在搖曳 時(shí)間: 2025-3-27 11:13
Development and Use of Platelet Glycoprotein Antagonists in Heart Diseasedisease (.). Although considerable effort has been expended to associate augmented platelet function with arterial thrombosis, it is more likely that the formation of platelet thrombi simply represents normal platelet function in the wrong location. It follows then that a rational approach to treati作者: convert 時(shí)間: 2025-3-27 15:34 作者: 紋章 時(shí)間: 2025-3-27 19:38
Nitric Oxide and Cardiac Ischemiaronary artery disease occurs, there is an abnormal diminished coronary blood supply relative to the myocardial oxygen demand known as hypoxia. The reduction in cardiac output is accompanied by increased systemic and pulmonary vascular resistance. These events are responsible for acute myocardial isc作者: arthroscopy 時(shí)間: 2025-3-28 01:39 作者: Obliterate 時(shí)間: 2025-3-28 02:08 作者: impale 時(shí)間: 2025-3-28 08:44
1557-2153 utting edge of scientific research and development around the world. This volume integrates basic and clinical cardiac pharmacology by c- bining, for the first time, both classical and molecular aspects of therapeutic drug development. The chapters comprise a broad spectrum of therapeutic areas and 作者: 稱贊 時(shí)間: 2025-3-28 12:52 作者: GOAD 時(shí)間: 2025-3-28 15:50 作者: puzzle 時(shí)間: 2025-3-28 20:40 作者: BIBLE 時(shí)間: 2025-3-29 00:14
Book 20011st editionr the long and often hard-earned experience of a number of researchers. Part III allows the reader to detect MMPs and TIMPs at both the protein and mRNA level, whereas Part IV gives the ability to assay MMP and TIMP activities in a wide variety of circumstances.作者: 恫嚇 時(shí)間: 2025-3-29 06:18 作者: 聲明 時(shí)間: 2025-3-29 07:52 作者: decipher 時(shí)間: 2025-3-29 14:11
https://doi.org/10.1007/978-981-19-5554-9data science practice; social data analytics research; evaluation science; social impact measurement; NG
