標題: Titlebook: Cancer, Complexity, Computation; Igor Balaz,Andrew Adamatzky Book 2022 The Editor(s) (if applicable) and The Author(s), under exclusive li [打印本頁] 作者: 技巧 時間: 2025-3-21 18:29
書目名稱Cancer, Complexity, Computation影響因子(影響力)
作者: 冥想后 時間: 2025-3-21 21:29 作者: 熄滅 時間: 2025-3-22 01:47
https://doi.org/10.1007/978-3-7908-1762-1ver, cancers exhibit an inherent evolving heterogeneity that requires an individual approach based on rigorous and precise predictions of cancer growth and treatment response. To this end, we advocate the use of quantitative in vivo imaging data to calibrate mathematical models for the personalized 作者: Bph773 時間: 2025-3-22 05:11 作者: Iniquitous 時間: 2025-3-22 10:30 作者: 鴿子 時間: 2025-3-22 13:47
https://doi.org/10.1007/978-3-319-38915-8he network, regulated by p300 and HDAC1, is modeled by a system of 14 ordinary differential equations. Based on this model, an oncogenic condition of Mdm2 overexpression is derived and the functional suppression of p53 is simulated as one possible carcinogenic behavior. Then, control action is intro作者: 鴿子 時間: 2025-3-22 20:45
H?vard Haarstad,Cecilia Camperoions in tumour system to timing and dosage of new treatments testing. When properly calibrated and validated, models can significantly improve our knowledge and contribute to narrowing clinical trials. In this study, we used the ODE model that includes only stem cells (wild and mutated) and differen作者: nonchalance 時間: 2025-3-23 01:16
https://doi.org/10.1007/BFb0043058e small number of clinically approved nanoparticles. Nanoparticle design is evolving in complexity, yet most experimental methods cannot keep up since they lack the proper resolution for accurate characterization and testing necessary for clinical approval. The computational approach can advance res作者: commensurate 時間: 2025-3-23 03:01
Telechelic oligomers by radical reactions,t differs from all previous known work using diploid representations. A form of the Baldwin effect has been identified as inherent to the evolutionary mechanisms of eukaryotes and a simplified version is presented here which maintains such behaviour. Using a well-known abstract tuneable model, it is作者: 秘密會議 時間: 2025-3-23 08:20 作者: 集合 時間: 2025-3-23 10:47
Alternative Aspects of Polythiophenesle the use of nanomedicines has increased in the clinic dramatically, problems persist over the lack of an agreed definition, creating difficulties for safety (including toxicity profiles), governance and transparency. This review assesses the utility of nanomedicines in healthcare, clarifying key c作者: nettle 時間: 2025-3-23 14:55 作者: blithe 時間: 2025-3-23 21:47 作者: Peculate 時間: 2025-3-23 23:41
Igor Balaz,Andrew AdamatzkyGives an unequivocal slice of all areas that relate to a quest for understanding cancer.Appeals to medical scientists, computer scientists, biologists, and mathematicians.Presents attractive reading f作者: Comprise 時間: 2025-3-24 04:07 作者: 刺耳 時間: 2025-3-24 10:18
https://doi.org/10.1057/9781137073723In modern society, with the constantly growing economy and demanding working and living conditions, a large portion of the population is facing stressful life that triggers chronic health problems like cancer, cardiovascular or neurological diseases.作者: stroke 時間: 2025-3-24 13:44 作者: GEM 時間: 2025-3-24 17:29 作者: 漂白 時間: 2025-3-24 21:37 作者: 花爭吵 時間: 2025-3-24 23:33 作者: FIN 時間: 2025-3-25 04:48 作者: OCTO 時間: 2025-3-25 08:12
,Pinning Control to?Regulate Cellular Response in?Cancer for?the?p53-Mdm2 Genetic Regulatory Networkduced to induce an increased expression of p53 levels and downregulation of Mdm2 and p53 activation using only three controlled states (pinned nodes) of the network for the first case and two states for the second case, respectively. The analytic results are simulated, which illustrate the feasibility of the proposed control scheme.作者: ALOFT 時間: 2025-3-25 14:32
A Haploid-Diploid Evolutionary Algorithm Optimizing Nanoparticle Based Cancer Treatments, shown that varying fitness landscape ruggedness varies the benefit of haploid-diploid algorithms. Moreover, the methodology is applied to optimise the targeted delivery of a therapeutic compound utilizing nano-particles to cancerous tumour cells with the multicellular simulator PhysiCell.作者: 謊言 時間: 2025-3-25 16:30 作者: Obsequious 時間: 2025-3-25 22:05
https://doi.org/10.1007/978-3-319-38915-8duced to induce an increased expression of p53 levels and downregulation of Mdm2 and p53 activation using only three controlled states (pinned nodes) of the network for the first case and two states for the second case, respectively. The analytic results are simulated, which illustrate the feasibility of the proposed control scheme.作者: 扔掉掐死你 時間: 2025-3-26 01:29 作者: 嘲笑 時間: 2025-3-26 05:26
2194-7287 biologists, and mathematicians.Presents attractive reading f.This book presents unique compendium of groundbreaking ideas where scientists from many different backgrounds are united in their interest in interdisciplinary approaches towards origins and development of cancers, innovative ways of searc作者: 征稅 時間: 2025-3-26 10:42 作者: cornucopia 時間: 2025-3-26 16:06 作者: 首創(chuàng)精神 時間: 2025-3-26 17:24
,Modeling Tumour Growth with?a?Modulated Game of?Life Cellular Automaton Under Global Coupling, only two free parameters. Parameter . governs the strength of a global coupling of the cells due to the confinement pressure. Parameter . governs the strength of the intercellular coupling which modulates the local dynamic rules of Conway’s Game of Life.作者: 口音在加重 時間: 2025-3-27 00:01
Drawbacks of Bench to Bed Translation of Nanomedicines for Cancer Treatment,n terms of reduced adverse effects and overcome?resistance of the chemotherapeutical drugs. Even though the potential of nanomedicines, its clinical translation still suboptimal. A new focus and new paradigm of this prospective scientific field is thus urgently needed.作者: Adulate 時間: 2025-3-27 04:17 作者: fructose 時間: 2025-3-27 06:20 作者: 預測 時間: 2025-3-27 12:53 作者: 合并 時間: 2025-3-27 15:17
,Quantitative In Vivo Imaging to?Enable Tumour Forecasting and?Treatment Optimization,nal methods designed to solve these models, thereby enabling their use for producing personalized tumour forecasts in silico, which, ultimately, can be used to not only predict response, but also optimize treatment. Finally, we discuss the main barriers to making the above paradigm a clinical reality.作者: 粗語 時間: 2025-3-27 18:30
The Effect of Over-Feeding in a Computational Model of Tumour Growth,th. On investigation it was ascertained that a single model parameter had been mistyped and that the nutrient supply had been set at a supra-physiological level. This study expands on this chance finding to explore the impact of over-feeding on tumour growth dynamics and its relation to response to cytotoxic treatment.作者: 磨坊 時間: 2025-3-28 00:59
Local Quantitative and Qualitative Sensitivity Analysis of CSC Dynamical Simulation,ata for breast tumour tissue. Obtained results indicate that even slight variations in initial values of signaling parameters can lead to considerable differences in tumour size over the course of 250?days. The model exerted the highest sensitivity to self-renewal probability for initial values above 0.5.作者: Chivalrous 時間: 2025-3-28 04:37 作者: 貿(mào)易 時間: 2025-3-28 09:12
What Cancer Is,e valid in all possible worlds in which cancer could logically exist. The grounds of cancer are then examined and elucidated. Two grounding cancer properties are identified and discussed: symmetry-breaking and computational intelligence. Each examination leads to concrete conclusions for novel thera作者: 確定方向 時間: 2025-3-28 11:33 作者: cocoon 時間: 2025-3-28 17:26 作者: seduce 時間: 2025-3-28 20:26
The Effect of Over-Feeding in a Computational Model of Tumour Growth,umour Growth (NEATG) model is a platform that has previously been used to explore aspects of tumour regrowth following cytotoxic treatment and the impact of tissue-cell communicative breakdown (anakoinosis) [.]. The model has been shown to recapitulate real-world tumour growth dynamics and display e作者: AMPLE 時間: 2025-3-29 01:29 作者: geriatrician 時間: 2025-3-29 03:06
,Pinning Control to?Regulate Cellular Response in?Cancer for?the?p53-Mdm2 Genetic Regulatory Networkhe network, regulated by p300 and HDAC1, is modeled by a system of 14 ordinary differential equations. Based on this model, an oncogenic condition of Mdm2 overexpression is derived and the functional suppression of p53 is simulated as one possible carcinogenic behavior. Then, control action is intro作者: Proclaim 時間: 2025-3-29 08:40
Local Quantitative and Qualitative Sensitivity Analysis of CSC Dynamical Simulation,ions in tumour system to timing and dosage of new treatments testing. When properly calibrated and validated, models can significantly improve our knowledge and contribute to narrowing clinical trials. In this study, we used the ODE model that includes only stem cells (wild and mutated) and differen作者: Virtues 時間: 2025-3-29 14:55
,The Role of?Molecular Dynamics Simulations in?Multiscale Modeling of?Nanocarriers for?Cancer Treatme small number of clinically approved nanoparticles. Nanoparticle design is evolving in complexity, yet most experimental methods cannot keep up since they lack the proper resolution for accurate characterization and testing necessary for clinical approval. The computational approach can advance res作者: 合唱團 時間: 2025-3-29 19:17
A Haploid-Diploid Evolutionary Algorithm Optimizing Nanoparticle Based Cancer Treatments,t differs from all previous known work using diploid representations. A form of the Baldwin effect has been identified as inherent to the evolutionary mechanisms of eukaryotes and a simplified version is presented here which maintains such behaviour. Using a well-known abstract tuneable model, it is作者: 歹徒 時間: 2025-3-29 20:44 作者: Chameleon 時間: 2025-3-30 03:07 作者: flourish 時間: 2025-3-30 07:05 作者: 谷物 時間: 2025-3-30 08:57 作者: 粘土 時間: 2025-3-30 16:08 作者: 使成核 時間: 2025-3-30 19:19 作者: Surgeon 時間: 2025-3-30 22:21
Correction to: The Immune System in Health and Disease: The Need for Personalised Longitudinal Moni作者: incubus 時間: 2025-3-31 01:38 作者: DOTE 時間: 2025-3-31 05:31 作者: 脆弱么 時間: 2025-3-31 09:44
Swarms: The Next Frontier for Cancer Nanomedicine,has now advanced to the point of being a useful tool for selecting nanoparticles that optimize treatment outcomes. We need to understand what the first-in-human clinical trial of nanoswarms should/will look like, and anticipate the associated ethical questions that may arise. To aid clinical adoptio作者: Narcissist 時間: 2025-3-31 16:47
Study of Tumour Induced Vessel Displacement in the Tumour Progression Rate with Advanced Bioinspireg to tumour growth, that heavily affect the aforementioned distribution of glucose?and oxygen?and, consequently and in turn, affect the tumour growth itself. The growth of a large number of tumours that initiated at various distances from a vessel, for the same number of time steps has been successf作者: opinionated 時間: 2025-3-31 21:04
Complexities of Drug Resistance in Cancer: An Overview of Strategies and Mathematical Models,nactivation, enhanced DNA repair, failure of apoptosis and modifications to tumour microenvironment. Several mathematical models have been proposed to describe the cellular heterogeneity of cancer in order to optimize the development of anti-cancer treatment. These models are based on differential e作者: 發(fā)牢騷 時間: 2025-3-31 23:20
2194-7287 cal and experimental results, concepts and paradigms...Distinctive features..The book advances widely popular topics of? cancer origin, treatment and understanding of its progress..The book is comprised of uniq978-3-031-04381-9978-3-031-04379-6Series ISSN 2194-7287 Series E-ISSN 2194-7295
