標題: Titlebook: Cancer Systems and Integrative Biology; Usha N. Kasid,Robert Clarke Book 2023 The Editor(s) (if applicable) and The Author(s), under exclu [打印本頁] 作者: audiogram 時間: 2025-3-21 19:01
書目名稱Cancer Systems and Integrative Biology影響因子(影響力)
書目名稱Cancer Systems and Integrative Biology影響因子(影響力)學科排名
書目名稱Cancer Systems and Integrative Biology網(wǎng)絡公開度
書目名稱Cancer Systems and Integrative Biology網(wǎng)絡公開度學科排名
書目名稱Cancer Systems and Integrative Biology被引頻次
書目名稱Cancer Systems and Integrative Biology被引頻次學科排名
書目名稱Cancer Systems and Integrative Biology年度引用
書目名稱Cancer Systems and Integrative Biology年度引用學科排名
書目名稱Cancer Systems and Integrative Biology讀者反饋
書目名稱Cancer Systems and Integrative Biology讀者反饋學科排名
作者: Contend 時間: 2025-3-21 22:53
Cancer Systems and Integrative Biology978-1-0716-3163-8Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 思想上升 時間: 2025-3-22 03:43
New Horizons for Asian Museums and Museologyerential gene expression between drug-resistant and sensitive cancers to identify genetic mediators of drug resistance. Here, we describe a comprehensive experimental and bioinformatic pipeline to isolate mRNA from human cell lines, prepare mRNA libraries for next-generation sequencing, and perform post-sequencing bioinformatics analyses.作者: confide 時間: 2025-3-22 05:19 作者: 挑剔小責 時間: 2025-3-22 09:54 作者: 開玩笑 時間: 2025-3-22 15:49
New Horizons for Asian Museums and Museology in cancer biology. Often focused on the use of large-scale, high-dimensional omics data for discovery in silico, integration with lower-dimensional data and lower-throughput wet laboratory studies allows for the development of a more mechanistic understanding of the control, execution, and operatio作者: 開玩笑 時間: 2025-3-22 18:12 作者: glucagon 時間: 2025-3-22 23:21 作者: 虛度 時間: 2025-3-23 03:07
New Horizons for Asian Museums and Museologyxchange mouse. Here we report the rationale for their development, the methods used to create them, and a brief summary of how MNX mice have been used to understand the contributions of mitochondrial DNA in multiple diseases, focusing on cancer metastasis. Polymorphisms in mtDNA which distinguish mo作者: 使腐爛 時間: 2025-3-23 09:16
Conference proceedings‘‘‘‘‘‘‘‘ 2016 for the culture medium. 3D-ACM enables tumor cells and/or tissues from an individual patient to proliferate in vitro. in a microenvironment that is very similar to their original, in vivo surroundings. The purpose is to maximally preserve in culture the native biological properties of a tumor. This作者: Acetaminophen 時間: 2025-3-23 11:41
New Horizons for Failing Heart Syndromeler (DSP, commercialized by nanoString) has become one of the dominant technologies in spatial transcriptomics and proteomics and has assisted in deconvoluting complex biological questions. Based on our practical experience in the past 3?years with DSP, we share here a detailed hands-on protocol and作者: cortisol 時間: 2025-3-23 17:40
https://doi.org/10.1007/978-4-431-66945-6nisms of drug resistance can lead to development of alternative therapies. One strategy is to subject drug-sensitive and drug-resistant variants to single-cell RNA-seq (scRNA-seq) and to subject the scRNA-seq data to network analysis to identify pathways associated with drug resistance. This protoco作者: galley 時間: 2025-3-23 20:47 作者: 休息 時間: 2025-3-24 01:14
Cardiac Utilization of the Momentum of Bloodetabolism. PPI are also considered to be involved in the pathogenesis and development of various diseases, including cancer. PPI phenomenon and their functions have been elucidated by gene transfection and molecular detection technologies. On the other hand, in histopathological analysis, although i作者: 黑豹 時間: 2025-3-24 02:35
New Horizons for Failing Heart Syndrome, metabolites) not captured via alternate genomic platforms. Unfortunately, downstream data analysis becomes complicated when attempting to evaluate and integrate measurements of different molecular classes and requires the aggregation of expertise from different relevant disciplines. This complexit作者: Bravura 時間: 2025-3-24 09:08
Cardiac Utilization of the Momentum of Bloodms cause human cancers to arise from a diverse set of specialized cell types and developmental states. Understanding these complex systems and their potential to drive cancer is critical for the development of immunotherapies and druggable targets. Pioneering single-cell?multi-omics technologies tha作者: 使糾纏 時間: 2025-3-24 12:16 作者: 鴕鳥 時間: 2025-3-24 15:30
Studies in Computational Intelligence increasingly important area of research is non-genetic cellular heterogeneity, a phenomenon that can be studied by assessing secretion of soluble effector proteins from single cells. This is particularly impactful for immune cells, as secreted proteins such as cytokines, chemokines, and growth fact作者: Amorous 時間: 2025-3-24 19:52
Rafael Burkhalter,Mario Bischof,Edy Portmanncarry cargo and target specific cells. Proper isolation, identification, and analytical strategy are required for evaluating their potential in diagnostics and therapeutics. Here, a method is detailed to isolate plasma EVs and analyze their proteomic profiling, combining EVtrap-based high-recovery E作者: hurricane 時間: 2025-3-25 00:32 作者: crescendo 時間: 2025-3-25 04:19
Studies in Computational Intelligenceaditional techniques such as immunohistochemistry, immunofluorescence, or flow cytometry limit the analysis of spatial data and cellular interactions within the TME, as they are restricted to colocalization of a small number of antigens or the loss of tissue architecture. Multiplex fluorescent immun作者: 侵害 時間: 2025-3-25 09:16
Dipankar Das,Prasanta Kumar Routular processes such as replication and transcription. To understand the specificity and biological consequences of DNA damage, it is essential to employ methods that are sensitive enough to detect damaged DNA bases at the level of single nucleotide resolution and genome-wide. Here we describe in det作者: opalescence 時間: 2025-3-25 14:45
https://doi.org/10.1007/978-3-319-21569-3uired to halt or reverse the progression of tumor growth. We intend to do this by utilizing a combinatorial approach in which CRISPR-directed gene editing is used to eliminate or significantly reduce the acquired resistance emerging from chemotherapy, radiation therapy, or immunotherapy. We will uti作者: Gourmet 時間: 2025-3-25 17:10
https://doi.org/10.1007/978-3-319-21569-3isease. According to the American Cancer Society, for all stages of pancreatic cancer combined, the 5-year survival rate is less than 10%. Genetic research on pancreatic cancer has generally been focused on familial pancreatic cancer, which is only 10% of all pancreatic cancer patients. This study f作者: 陳舊 時間: 2025-3-25 22:41 作者: Resistance 時間: 2025-3-26 03:46
978-1-0716-3165-2The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines作者: Antagonist 時間: 2025-3-26 05:10 作者: DEMN 時間: 2025-3-26 11:47 作者: 高度 時間: 2025-3-26 13:35
Cardiac Utilization of the Momentum of Blood SPaRTAN uses CITE-seq (cellular indexing of transcriptomes and epitopes by sequencing) data and cis-regulatory sites to model the effect of interactions between transcription factors and cell-surface receptors on gene expression. We demonstrate the pipeline for SPaRTAN using CITE-seq data from peripheral blood mononuclear cells.作者: finale 時間: 2025-3-26 20:38 作者: KIN 時間: 2025-3-26 21:22
Studies in Computational Intelligence (CF) lung epithelial cells using .[S] methionine or .[P] and the consequences of repair by gene therapy with [wildtype] CFTR. This novel antibody microarray-based technology identifies relevant, hidden proteins whose regulation by the CF genotype would never have been detected by simple measurements of total proteomic masses.作者: Epithelium 時間: 2025-3-27 01:48
https://doi.org/10.1007/978-3-319-21569-3onto this therapeutic approach. We envision delivering these molecules by direct injection into solid tumors for the treatment of squamous cell carcinomas of the lung, esophageal cancer, and head and neck cancer. We provide experimental details and methodology for utilizing CRISPR/Cas as a supplement to chemotherapy to destroy lung cancer cells.作者: 文件夾 時間: 2025-3-27 06:39 作者: 典型 時間: 2025-3-27 10:24 作者: Incumbent 時間: 2025-3-27 17:12
Discovery of a Hidden Proinflammatory Signaling Proteome Using a Large-Scale, Targeted Antibody Mic (CF) lung epithelial cells using .[S] methionine or .[P] and the consequences of repair by gene therapy with [wildtype] CFTR. This novel antibody microarray-based technology identifies relevant, hidden proteins whose regulation by the CF genotype would never have been detected by simple measurements of total proteomic masses.作者: Bridle 時間: 2025-3-27 21:13 作者: APEX 時間: 2025-3-28 01:52 作者: neuron 時間: 2025-3-28 02:17 作者: Protein 時間: 2025-3-28 08:45 作者: 小官 時間: 2025-3-28 13:44
New Horizons for Asian Museums and Museologyreactive oxygen species, altering the microbiota, and influencing immune responses to cancer cells. Although the focus of this report is cancer metastasis, MNX mice have proven to be valuable in studying mitochondrial contributions to other diseases as well.作者: 口訣法 時間: 2025-3-28 15:50
Dipankar Das,Prasanta Kumar Routs damaged bases and conversion of the damaged sites into double-strand breaks using specific DNA repair enzymes. Library sequencing of the opened circles yields the precise positions of the DNA lesions that are present. CD-seq can be adopted to various types of DNA damage as long as a specific cleavage scheme can be designed.作者: thalamus 時間: 2025-3-28 21:43
Generating Mitochondrial-Nuclear Exchange (MNX) Mice to Identify Mitochondrial Determinants of Cancreactive oxygen species, altering the microbiota, and influencing immune responses to cancer cells. Although the focus of this report is cancer metastasis, MNX mice have proven to be valuable in studying mitochondrial contributions to other diseases as well.作者: 水獺 時間: 2025-3-29 00:51 作者: 涂掉 時間: 2025-3-29 06:20 作者: 鉗子 時間: 2025-3-29 11:18 作者: APEX 時間: 2025-3-29 13:19
New Horizons for Failing Heart Syndromenvoluting complex biological questions. Based on our practical experience in the past 3?years with DSP, we share here a detailed hands-on protocol and key handling notes that will allow the broader community to optimize their work procedure.作者: semble 時間: 2025-3-29 17:29
Genome-Wide Analysis of Palindrome Formation with Next-Generation Sequencing (GAPF-Seq) and a Bioind replication forks, all of which are common adverse early events in cancer. Here, we describe the protocol for enriching palindromes from genomic DNA sources with low-input DNA amounts and detail a bioinformatics tool for assessing the enrichment and location of de novo palindrome formation from low-coverage whole-genome sequencing data.作者: Lumbar-Spine 時間: 2025-3-29 22:12 作者: 佛刊 時間: 2025-3-30 02:11 作者: Occipital-Lobe 時間: 2025-3-30 07:37
Integration of Single-Cell RNA-Sequencing and Network Analysis to Investigate Mechanisms of Drug Rel describes a computational analysis pipeline to study drug resistance by subjecting scRNA-seq expression data to Passing Attributes between Networks for Data Assimilation (PANDA), an integrative network analysis tool that incorporates protein–protein interactions (PPI) and transcription factor (TF)-binding motifs.作者: giggle 時間: 2025-3-30 11:14
Isolation and Identification of Plasma Extracellular Vesicles Protein Biomarkers,V isolation, phase-transfer surfactant method for protein extraction, and mass spectrometry qualitative and quantitative strategies for EV proteome characterization. The pipeline provides a highly effective EV-based proteome analysis technique that can be applied for EV characterization and evaluation of EV-based diagnosis and therapy.作者: OVERT 時間: 2025-3-30 13:33 作者: apiary 時間: 2025-3-30 17:29
Genome-Wide Analysis of Palindrome Formation with Next-Generation Sequencing (GAPF-Seq) and a Biointhat are identical to their reverse complements and often arise due to illegitimate repair of DNA double-strand breaks, fusion of telomeres, or stalled replication forks, all of which are common adverse early events in cancer. Here, we describe the protocol for enriching palindromes from genomic DNA作者: BALE 時間: 2025-3-30 22:15
Sample Preparation and Differential Gene Expression Analysis of Human Cancer Cell Lines by RNA Sequerential gene expression between drug-resistant and sensitive cancers to identify genetic mediators of drug resistance. Here, we describe a comprehensive experimental and bioinformatic pipeline to isolate mRNA from human cell lines, prepare mRNA libraries for next-generation sequencing, and perform 作者: 字形刻痕 時間: 2025-3-31 02:26 作者: 有特色 時間: 2025-3-31 05:22
3D-Autologous Culture Method for Precision Oncology, for the culture medium. 3D-ACM enables tumor cells and/or tissues from an individual patient to proliferate in vitro. in a microenvironment that is very similar to their original, in vivo surroundings. The purpose is to maximally preserve in culture the native biological properties of a tumor. This作者: 大吃大喝 時間: 2025-3-31 09:37 作者: alcohol-abuse 時間: 2025-3-31 14:01
Integration of Single-Cell RNA-Sequencing and Network Analysis to Investigate Mechanisms of Drug Renisms of drug resistance can lead to development of alternative therapies. One strategy is to subject drug-sensitive and drug-resistant variants to single-cell RNA-seq (scRNA-seq) and to subject the scRNA-seq data to network analysis to identify pathways associated with drug resistance. This protoco作者: nostrum 時間: 2025-3-31 17:35
Combination of Tissue Microarray Profiling and Multiplexed IHC Approaches to Investigate Transport py or in combination with other established anticancer or pharmacological agents. To date, nearly a dozen anticancer NAs are approved by the FDA, and several novel NAs are being tested in preclinical and clinical trials for future applications. However, improper delivery of NAs into tumor cells beca作者: 跟隨 時間: 2025-3-31 22:56 作者: Relinquish 時間: 2025-4-1 04:45 作者: 直覺沒有 時間: 2025-4-1 07:25
