標(biāo)題: Titlebook: Cancer Drug Resistance; Overviews and Method Jose Rueff,António Sebasti?o Rodrigues Book 2016 Springer Science+Business Media New York 2016 [打印本頁(yè)] 作者: 可擴(kuò)大 時(shí)間: 2025-3-21 17:10
書(shū)目名稱(chēng)Cancer Drug Resistance影響因子(影響力)
書(shū)目名稱(chēng)Cancer Drug Resistance影響因子(影響力)學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance網(wǎng)絡(luò)公開(kāi)度
書(shū)目名稱(chēng)Cancer Drug Resistance網(wǎng)絡(luò)公開(kāi)度學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance被引頻次
書(shū)目名稱(chēng)Cancer Drug Resistance被引頻次學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance年度引用
書(shū)目名稱(chēng)Cancer Drug Resistance年度引用學(xué)科排名
書(shū)目名稱(chēng)Cancer Drug Resistance讀者反饋
書(shū)目名稱(chēng)Cancer Drug Resistance讀者反饋學(xué)科排名
作者: obsession 時(shí)間: 2025-3-21 20:29 作者: exigent 時(shí)間: 2025-3-22 03:35
Cancer Drug Resistance978-1-4939-3347-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 作者: 癡呆 時(shí)間: 2025-3-22 05:29
Yu. A. Izyumov,V. E. Naish,R. P. Ozerovthe patient’s genetic makeup or be acquired by tumors that are initially sensitive to cancer drugs. All in all, it may be responsible for treatment failure in over 90 % of patients with metastatic cancer. Cancer drug resistance, in particular acquired resistance, may stem from the micro-clonality/mi作者: 的是兄弟 時(shí)間: 2025-3-22 10:15 作者: 浪費(fèi)時(shí)間 時(shí)間: 2025-3-22 15:03 作者: 浪費(fèi)時(shí)間 時(shí)間: 2025-3-22 18:23 作者: 我們的面粉 時(shí)間: 2025-3-23 00:58
https://doi.org/10.1007/978-0-387-78693-3cquire multidrug resistance (MDR) and no longer respond to chemotherapy. Efflux transporters play a predominant role in mediating MDR. Cellular accumulation (uptake) and permeability studies serve as invaluable methods to detect drug efflux/transport mechanism. These methods are generally performed 作者: HACK 時(shí)間: 2025-3-23 01:50 作者: 廢墟 時(shí)間: 2025-3-23 07:47
Neutron Imaging for the Hydrogen Economyporters, and has been associated with drug resistance in eukaryotic cells. Multidrug resistance (MDR) is related to an increased expression and function of the ABCB1 (P-gp) efflux pump that often causes chemotherapeutic failure in cancer. Modulators of this efflux pump, such as the calcium channel b作者: diathermy 時(shí)間: 2025-3-23 10:52 作者: 原諒 時(shí)間: 2025-3-23 17:33
https://doi.org/10.1007/978-94-009-4636-1ding RNAs (20–22 nt in length) that bind imperfectly to the 3′-untranslated region of target mRNA, has been insistently implicated in several pathological conditions including cancer. Indeed, major hallmarks of cancer, such as cell differentiation, cell proliferation, cell cycle, cell survival, and 作者: 不真 時(shí)間: 2025-3-23 20:27
A. Denker,N. Kardjilov,B. Schr?der-Smeibidlatients alive 5-years after diagnosis. The therapeutic options for metastatic PDAC have changed in the past few years from single agent gemcitabine treatment to combination regimens. Nowadays, FOLFIRINOX or gemcitabine with nab-paclitaxel are new standard combinations in frontline metastatic setting作者: 草率女 時(shí)間: 2025-3-23 22:18 作者: 彎曲道理 時(shí)間: 2025-3-24 03:43 作者: Debility 時(shí)間: 2025-3-24 07:01
Neutron Activation Autoradiographyis, but also of resistance to therapy. Exosomes are small membrane vesicles of endocytic origin, which contain mRNAs, DNA fragments, and proteins, and are released by many different cell types, including cancer cells. Mounting evidence has shown that cancer-derived exosomes contribute to the recruit作者: duplicate 時(shí)間: 2025-3-24 14:08 作者: GOAT 時(shí)間: 2025-3-24 17:07 作者: Malleable 時(shí)間: 2025-3-24 22:27 作者: Cardiac 時(shí)間: 2025-3-25 02:20 作者: Autobiography 時(shí)間: 2025-3-25 05:37 作者: 嘲弄 時(shí)間: 2025-3-25 08:25 作者: Dignant 時(shí)間: 2025-3-25 14:58 作者: B-cell 時(shí)間: 2025-3-25 18:53
Yu. A. Izyumov,V. E. Naish,R. P. Ozerovs; role of epigenomics/epistasis by methylation, acetylation, and altered levels of microRNAs leading to alterations in upstream or downstream effectors; mutation of drug targets in targeted therapy and alterations in the cell cycle and checkpoints; and tumor microenvironment that are briefly reviewed.作者: Repatriate 時(shí)間: 2025-3-25 23:47
https://doi.org/10.1007/978-94-009-4636-1at tend to metastasize to distant organs. Hence, with this review, we aim to summarize the miRs that influence molecular pathways that are involved in cancer drug resistance, such as drug metabolism, drug influx/efflux, DNA damage response (DDR), epithelial-to-mesenchymal transition (EMT), and cancer stem cells.作者: Callus 時(shí)間: 2025-3-26 02:23 作者: arousal 時(shí)間: 2025-3-26 05:22 作者: aristocracy 時(shí)間: 2025-3-26 12:07 作者: 反復(fù)拉緊 時(shí)間: 2025-3-26 15:54 作者: TIA742 時(shí)間: 2025-3-26 19:06 作者: 憎惡 時(shí)間: 2025-3-27 00:13 作者: 煩擾 時(shí)間: 2025-3-27 04:37
Isolation and Characterization of Cancer Stem Cells from Primary Head and Neck Squamous Cell Carcintudies exploring the mechanisms underlying the role of these cells in chemoresistance. Here, we describe a method to isolate cancer stem cells from primary head and neck tumors and for the generation of orospheres.作者: Distribution 時(shí)間: 2025-3-27 08:07 作者: irritation 時(shí)間: 2025-3-27 11:54 作者: exostosis 時(shí)間: 2025-3-27 17:24 作者: 佛刊 時(shí)間: 2025-3-27 18:11 作者: 消極詞匯 時(shí)間: 2025-3-28 00:14
Applications of Elementary Diffusion Theorysignificant role to interpret this complex data into useful conclusions. In this chapter, the use of bioinformatics platforms, particularly CancerDR, in understanding the cancer drug resistance is described.作者: Mnemonics 時(shí)間: 2025-3-28 03:16 作者: 津貼 時(shí)間: 2025-3-28 06:34
Cancer Exosomes as Mediators of Drug Resistance,ug resistance will allow novel and better strategies to overcome drug resistance and treat cancer..Here, we describe a technique for exosome purification from cell culture, and fresh and frozen plasma, and further analysis by electron microscopy, NanoSight microscope, and Western blot.作者: 吸引力 時(shí)間: 2025-3-28 11:22 作者: 異常 時(shí)間: 2025-3-28 16:20
Managing Drug Resistance in Cancer: Role of Cancer Informatics,significant role to interpret this complex data into useful conclusions. In this chapter, the use of bioinformatics platforms, particularly CancerDR, in understanding the cancer drug resistance is described.作者: 元音 時(shí)間: 2025-3-28 19:39
Neutron Imaging for Aerospace Applications,o monitor DNA damage and repair capacity as well as the use of clonogenic and β-galactosidase staining assays to assess long-term cell fate after DNA-damaging treatment. Finally, we also present examples of these methods currently used in our laboratory for studying the role of FOXM1 in DNA damage-induced senescence and epirubicin resistance.作者: 注射器 時(shí)間: 2025-3-29 01:12
https://doi.org/10.1007/978-0-387-78693-3on transfected cells (e.g., MDCKII-MDR1, MDCKII-MRP2, and MDCKII-BCRP) or cells expressing high amount of intrinsic efflux transporters (Caco-2) utilizing specific inhibitors as positive controls. This chapter presents a method of performing uptake and permeability studies, including the preparation of various buffers required for the study.作者: micturition 時(shí)間: 2025-3-29 04:52 作者: ASSAY 時(shí)間: 2025-3-29 08:51
https://doi.org/10.1007/BFb0041485the response to NACT is a valuable indicator of long-term survival. In this work, the advantages and pitfalls of using NAST in BC for studying drug response and resistance for drug development and clinical trials are discussed as well as practical points on how to set up a NAST clinical trial in BC.作者: SLUMP 時(shí)間: 2025-3-29 14:19 作者: 知識(shí) 時(shí)間: 2025-3-29 19:26
Classical and Targeted Anticancer Drugs: An Appraisal of Mechanisms of Multidrug Resistance,ot only as a consequence of drug therapy but also by apoptosis induced by their microenvironment. Cell death can be mediated by host immune mechanisms and by nonimmune cells acting on so-called death receptors. The tumor cell proliferation rate is also important because it controls tumor regeneratio作者: 貪婪地吃 時(shí)間: 2025-3-29 23:39 作者: Negotiate 時(shí)間: 2025-3-30 00:33 作者: 松雞 時(shí)間: 2025-3-30 06:10 作者: mediocrity 時(shí)間: 2025-3-30 10:23 作者: Insulin 時(shí)間: 2025-3-30 13:58 作者: drusen 時(shí)間: 2025-3-30 18:19 作者: Tdd526 時(shí)間: 2025-3-30 20:55
Erratum to: In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic 作者: 使尷尬 時(shí)間: 2025-3-31 02:00 作者: 分解 時(shí)間: 2025-3-31 07:59 作者: HEED 時(shí)間: 2025-3-31 10:55
Neutron Imaging and Applicationseated with TKIs, more cases of resistance are expected and the discovery of biomarkers of resistance acquires a crucial clinical significance..We established a valuable in vitro experimental system that mimics the acquired resistance in the absence of mutations. It was developed by the continuous ex作者: Modicum 時(shí)間: 2025-3-31 14:51
Neutron Imaging for the Hydrogen Economyuse of ABCB1-transfected mouse T-lymphoma cell line to study the uptake/efflux of fluorescent probes like ethidium bromide (EB), rhodamine 123 (Rh-123), and carbocyanine dye DiOC., in the presence and absence of potential inhibitors, is currently used in our laboratories to evaluate the ability of a作者: Crohns-disease 時(shí)間: 2025-3-31 19:12
M. Arif,D.S. Hussey,D.L. Jacobson, PI3K/AKT/mTOR inhibitors, RAS/RAF/MEK/ERK/MAPK inhibitors, and antiangiogenic drugs. In spite of the many advances in controlling the division of BC cells and the progression of BC tumors these still remain the main cause of death among women in age range of 20–50 years requiring even more efforts作者: 狂怒 時(shí)間: 2025-3-31 21:54 作者: menopause 時(shí)間: 2025-4-1 04:01 作者: MARS 時(shí)間: 2025-4-1 07:45 作者: Anhydrous 時(shí)間: 2025-4-1 10:41
Classical and Targeted Anticancer Drugs: An Appraisal of Mechanisms of Multidrug Resistance, for more than 30 years. The identification of P-glycoprotein (P-gp), a drug efflux transporter protein with affinity for multiple therapeutic drugs, provided an important potential mechanism and further work, which identified other members of ATP-binding cassette (ABC) family that act as drug trans作者: GAVEL 時(shí)間: 2025-4-1 17:02
In Vitro Methods for Studying the Mechanisms of Resistance to DNA-Damaging Therapeutic Drugs, mechanism that enables cancer cells to survive through eliminating the damaged DNA lesions and thereby developing resistance to DNA-damaging agents. This chapter describes the four experimental approaches for studying DDR and genotoxic drug resistance, including the use of γ-H2AX and comet assays t
