標(biāo)題: Titlebook: Calorie Restriction, Aging and Longevity; Arthur V. Everitt,Suresh I. S. Rattan,Rafael Cabo Book 2010 Springer Science+Business Media B.V. [打印本頁] 作者: 底的根除 時間: 2025-3-21 16:23
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作者: 悄悄移動 時間: 2025-3-21 22:02
Food Intake, Life Style, Aging and Human Longevityithout malnutrition retards primary aging, delays the onset of age-related diseases and extends life by 20–50%. No life-long CR-survival studies exist in humans. However, Okinawans on 40% CR for half their adult life live 4 years longer than Americans. Overeating leading to obesity in middle age red作者: saphenous-vein 時間: 2025-3-22 01:58
Okinawa: A Naturally Calorie Restricted Population birth, life expectancy at older ages, centenarian prevalence and other measures of longevity. In order to examine the potential contribution of caloric restriction (CR) to this longevity phenomenon, we review the medical, epidemiologic and demographic evidence for CR in this population. Energy inta作者: 整潔漂亮 時間: 2025-3-22 07:24
Aging and the Effect of Calorie Restriction in Rhesus Monkeysand result in several health benefits in many short-lived species. Beginning about 20 years ago, well-controlled long-term studies initiated at both the National Institute on Aging and the Wisconsin National Primate Research Center have been investigating the effect of CR in long-lived rhesus monkey作者: 拔出 時間: 2025-3-22 12:44
Dietary Restriction and Aging in , nd the life span of a variety of organisms. . is ideally suited for experiments into the biological effects of DR and aging due to its short life span and thorough characterization at the molecular and genetic level. Furthermore, the simple sugar/yeast diet (corresponding to carbohydrate and protein作者: intrigue 時間: 2025-3-22 15:23 作者: intrigue 時間: 2025-3-22 19:48
The Nutritional Geometry of Agingrient effects are involved. Here it is shown how the development of state-space geometric models in nutrition (the Geometric Framework) has provided a new approach to separating the effects of calories and nutrients. We introduce the models and illustrate their use in three recent studies on insects作者: Cumulus 時間: 2025-3-22 21:20 作者: 積極詞匯 時間: 2025-3-23 02:46
Calorie Restriction Mimetics and Agingude resveratrol, catechins, quercetin and genistein. There is considerable overlap between these pathways and those activated by caloric restriction. The chemicals have therefore been termed “calorie restriction mimetics”. In both cases the response induced steels the cell to resist adverse or stres作者: 虛度 時間: 2025-3-23 06:04 作者: 愛管閑事 時間: 2025-3-23 12:32 作者: GULP 時間: 2025-3-23 14:56
Food Restriction, Hormones, Genes and Agings show that when young male Wistar rats aged 60 days are hypophysectomized (HYP) and receive 1?mg cortisone once per week and the same amount of food as food restricted (FR) rats they age more slowly than control (C) or FR rats. HYP rats have the slowest aging in collagen fibre strength, kidney base作者: Gesture 時間: 2025-3-23 21:25 作者: RUPT 時間: 2025-3-23 23:15 作者: 抗體 時間: 2025-3-24 04:47 作者: 哪有黃油 時間: 2025-3-24 09:39
, changes. Special emphasis is given to the first completed clinical studies which have investigated the effects of controlled, high-quality energy-restricted diets on both biomarkers of longevity and on risk factors for the development of chronic diseases of aging. Prolonged CR has been shown to ext作者: mechanism 時間: 2025-3-24 12:04
on health and life-span effects of Calorie Restriction.Cove.Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in heal作者: BUDGE 時間: 2025-3-24 17:20 作者: 緩解 時間: 2025-3-24 21:05 作者: Discrete 時間: 2025-3-24 23:39 作者: collagenase 時間: 2025-3-25 04:33
https://doi.org/10.1007/978-3-031-60183-5. Data from these organisms demonstrate that it is not calories per se that drives the relationship between diet and longevity, but rather the ratio of protein to non-protein energy ingested. It is argued that similar geometric analysis is required for mammalian model systems.作者: Senescent 時間: 2025-3-25 11:10 作者: bizarre 時間: 2025-3-25 14:22 作者: headway 時間: 2025-3-25 17:24
Neurocomputational Models of Time Perceptionderstanding of the effects of CR on learning and memory. As the reader will discern, the hypothesis that CR is beneficial to learning and memory in senescent animals is only partially supported by the current data.作者: Somber 時間: 2025-3-25 20:03
Thomas H. Rammsayer,Stefan J. Troche restriction appears to act via discrete cellular mechanisms such as sirtuin pathways that impact cellular bioenergetics, apoptosis and other cellular functions. The liver has as a pivotal coordinating role when dietary intake is reduced, therefore many of the effects of caloric restriction are mediated by the liver.作者: Synovial-Fluid 時間: 2025-3-26 01:16 作者: 心痛 時間: 2025-3-26 07:35
https://doi.org/10.1007/978-1-4615-8618-0. Also discussed are some of the possible caloric restriction-induced cellular mechanisms by which age-related vascular oxidative stress and inflammation can be delayed or reversed thereby improving cardiovascular health in the elderly.作者: surmount 時間: 2025-3-26 08:49 作者: 刺激 時間: 2025-3-26 12:55 作者: 血友病 時間: 2025-3-26 17:00
The Aging Liver and the Effects of Long Term Caloric Restriction restriction appears to act via discrete cellular mechanisms such as sirtuin pathways that impact cellular bioenergetics, apoptosis and other cellular functions. The liver has as a pivotal coordinating role when dietary intake is reduced, therefore many of the effects of caloric restriction are mediated by the liver.作者: 確定方向 時間: 2025-3-26 21:08 作者: 寬敞 時間: 2025-3-27 01:22
Caloric Restriction and Cardiovascular Disease. Also discussed are some of the possible caloric restriction-induced cellular mechanisms by which age-related vascular oxidative stress and inflammation can be delayed or reversed thereby improving cardiovascular health in the elderly.作者: 傻瓜 時間: 2025-3-27 08:31 作者: legislate 時間: 2025-3-27 10:10 作者: 雄偉 時間: 2025-3-27 15:18 作者: 魔鬼在游行 時間: 2025-3-27 20:46 作者: 圓錐 時間: 2025-3-27 21:56
https://doi.org/10.1007/978-3-031-60183-5nd the life span of a variety of organisms. . is ideally suited for experiments into the biological effects of DR and aging due to its short life span and thorough characterization at the molecular and genetic level. Furthermore, the simple sugar/yeast diet (corresponding to carbohydrate and protein作者: OCTO 時間: 2025-3-28 02:57
Hugo Merchant,Victor de Lafuente. is perhaps the simplest among the major model organisms established for studies of calorie restriction and aging since it is unicellular, easily manipulated genetically, amenable to a number of powerful genome/proteome-wide screening techniques, and the genes that regulates its life span play simi作者: 相信 時間: 2025-3-28 06:52
https://doi.org/10.1007/978-3-031-60183-5rient effects are involved. Here it is shown how the development of state-space geometric models in nutrition (the Geometric Framework) has provided a new approach to separating the effects of calories and nutrients. We introduce the models and illustrate their use in three recent studies on insects作者: Inoperable 時間: 2025-3-28 10:49
Neurobiology of Interval Timing vertebrate species. In spite of significant research effort however, the biochemical mechanism underlying this effect still remains to be resolved. Although a body of data supports the interpretation that DR feeding regimes reduce the intensity of oxidative stress and damage in tissues of older ani作者: Jogging 時間: 2025-3-28 15:16 作者: 表示向下 時間: 2025-3-28 19:40
Neurocomputational Models of Time Perception the brain and brain function are less well known and understood. In this chapter the effect of long-term CR on learning and memory in aging populations of laboratory rats and mice is evaluated. Included in this chapter is a discussion of the methodological issues that investigators must consider in作者: 阻撓 時間: 2025-3-29 00:50
Thomas H. Rammsayer,Stefan J. Trochel cell morphology. These changes are associated with significant impairment of many hepatic metabolic and detoxification activities. This has implications for systemic aging and age-related disease. For example the age-related impairment of the hepatic metabolism of lipoproteins predisposes to cardi作者: machination 時間: 2025-3-29 03:35 作者: buoyant 時間: 2025-3-29 08:16
Neurobiology of Interval Timingriction (CR) generally stimulates various maintenance and repair systems, hormesis has been considered as one of the possible mechanisms. The evidence in favour of the hormetic explanation for the beneficial effects of CR includes the induction of various stress responses including heat shock respon作者: 誹謗 時間: 2025-3-29 12:09
Catherine R. G. Jones,Marjan Jahanshahilemented is daily calorie restriction (CR), which involves decreasing energy intake by a certain percentage daily. Another dietary restriction regimen employed, although far less commonly, is alternate day fasting (ADF). ADF regimens include a “feed day” where food is consumed ad libitum, alternated作者: FLIC 時間: 2025-3-29 18:56
https://doi.org/10.1007/978-1-4615-8618-0ietary regimen known as caloric restriction, undernutrition without malnutrition, delays the onset of aging and extends lifespan in laboratory animal models. Evidence supporting the role of caloric restriction intervening in the cardiovascular aging process by preventing the development of cardiovas作者: 恃強(qiáng)凌弱的人 時間: 2025-3-29 21:49 作者: Finasteride 時間: 2025-3-30 01:18
https://doi.org/10.1007/978-90-481-8556-6Diabetes; Drosophila; Endoplasmatisches Reticulum; ageing; aging; cancer; nutrition; obesity; oxidative stre作者: Nausea 時間: 2025-3-30 06:11
978-94-007-9115-2Springer Science+Business Media B.V. 2010作者: 俗艷 時間: 2025-3-30 09:54 作者: Antagonism 時間: 2025-3-30 15:27
http://image.papertrans.cn/c/image/220935.jpg作者: 語言學(xué) 時間: 2025-3-30 20:00
shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this 978-94-007-9115-2978-90-481-8556-6作者: kyphoplasty 時間: 2025-3-30 21:44 作者: 沒有貧窮 時間: 2025-3-31 04:12
History of Caloric Restriction, Aging and Longevitynderlying the life extension is the reduction in energy intake; thus the term caloric restriction (CR) has been widely used when referring to this phenomenon. Over the years, CR has been reported to retard a spectrum of age-associated diseases and the aging of many physiological processes. Also, hyp作者: apiary 時間: 2025-3-31 07:10
Food Intake, Life Style, Aging and Human Longevityhealthy lifestyle of consuming a prudent diet (high in fruit, vegetables, whole grains and fish), maintaining a normal body weight, performing daily physical exercise and not smoking which leads to a 55% reduction in all-cause mortality over 24 years. During the twentieth century life expectancy at 作者: 脆弱么 時間: 2025-3-31 10:34
Aging and the Effect of Calorie Restriction in Rhesus Monkeysystems. More recently, work has focused on both behavioral and immune function alterations and thus this review emphasizes some of these findings and provides an update on female reproductive studies and sarcopenia.作者: Enteropathic 時間: 2025-3-31 13:40 作者: 阻礙 時間: 2025-3-31 17:40 作者: 舊式步槍 時間: 2025-4-1 01:38 作者: Polydipsia 時間: 2025-4-1 04:52
Food Restriction, Hormones, Genes and Agingone as well. Study of the interaction of mouse longevity genes with FR have revealed differential responses in endocrine mutants. In Ames dwarfs, FR produced further increases in insulin sensitivity and longevity. In contrast, identical regimen of FR in GHRKO mice did not further augment their insul作者: Clumsy 時間: 2025-4-1 06:28
