作者: 專橫 時間: 2025-3-21 23:37 作者: 起波瀾 時間: 2025-3-22 02:15 作者: 伸展 時間: 2025-3-22 05:49
The Na+/Ca2+ Exchanger: Structural Aspects, Function and Regulation,diated by the calmodulin-dependent protein phosphatase calcineurin. The regulatory mechanisms of autoinhibition and activation by Ca. and ATP are linked to domains in the large central cytosolic loop of the protein.作者: LURE 時間: 2025-3-22 10:01
https://doi.org/10.1007/978-3-642-87673-8 distributions, as well as by differing affinities and binding rates of calcium-modulated proteins. The focus of this review is to summarize the characteristics of the 66 known subfamilies of EF-hand proteins and to suggest general patterns of their evolution.作者: projectile 時間: 2025-3-22 13:03 作者: projectile 時間: 2025-3-22 19:10 作者: MOAT 時間: 2025-3-23 00:04
https://doi.org/10.1007/978-3-642-81964-3diated by the calmodulin-dependent protein phosphatase calcineurin. The regulatory mechanisms of autoinhibition and activation by Ca. and ATP are linked to domains in the large central cytosolic loop of the protein.作者: MOCK 時間: 2025-3-23 04:47 作者: 終點 時間: 2025-3-23 08:22 作者: 橢圓 時間: 2025-3-23 11:20
https://doi.org/10.1007/978-3-642-81964-3ferent substrates. CaMkinases are involved in the regulation of many different cellular processes such as neurotransmitter release, muscle contraction, cell proliferation, gene expression, and long term potentiation and depression. Their participation in these different regulatory pathways are evaluated.作者: jabber 時間: 2025-3-23 17:21
https://doi.org/10.1007/978-3-642-81964-3urements, mutational analysis and structural studies have produced a considerable body of information on this system. That information is discussed here in order to unveil relationships of structure and function within the ATPase protein, and to clarify the coupling mechanism of ATP hydrolysis and Ca. transport at the molecular level.作者: patriot 時間: 2025-3-23 20:05
Calcium Homeostasis and Its Evolution, balance and of the environment are stressed. Homeostasis can only be managed by the continuous use of energy and, for any one element, here calcium, has to depend on the balanced flow of many others.作者: 礦石 時間: 2025-3-24 01:07
Calmodulin-Dependent Protein Kinases,ferent substrates. CaMkinases are involved in the regulation of many different cellular processes such as neurotransmitter release, muscle contraction, cell proliferation, gene expression, and long term potentiation and depression. Their participation in these different regulatory pathways are evaluated.作者: Basal-Ganglia 時間: 2025-3-24 03:08 作者: 流眼淚 時間: 2025-3-24 08:43
1437-7993 (s) are also described. The volume is a valuable source of information for graduate students and researchers who want to acquaint themselves with various aspects extracellular calcium. .978-3-642-63532-8978-3-642-58306-3Series ISSN 1437-7993 作者: 帶來墨水 時間: 2025-3-24 12:19 作者: 放棄 時間: 2025-3-24 18:23
https://doi.org/10.1007/978-3-642-87673-8cidated. This review presents the latest advances in the field of calmodulin and its target proteins, with particular emphasis on the structural basis underlying multi-target recognition processes conducted by this Ca.-dependent cellular activator.作者: 恩惠 時間: 2025-3-24 19:33 作者: collagen 時間: 2025-3-24 23:44
Calmodulin Target Recognition: Common Mechanism and Structural Diversity,cidated. This review presents the latest advances in the field of calmodulin and its target proteins, with particular emphasis on the structural basis underlying multi-target recognition processes conducted by this Ca.-dependent cellular activator.作者: 一小塊 時間: 2025-3-25 04:12 作者: AVOID 時間: 2025-3-25 10:13 作者: 懶惰民族 時間: 2025-3-25 15:14
Ernesto Carafoli,Joachim KrebsThe companion book series to the "Journal of Biological Inorganic Chemistry".Includes supplementary material: 作者: 就職 時間: 2025-3-25 16:45 作者: Aggressive 時間: 2025-3-25 22:01 作者: 枕墊 時間: 2025-3-26 03:40
978-3-642-63532-8Springer-Verlag Berlin Heidelberg 2000作者: STEER 時間: 2025-3-26 05:30
,Steuersysteme für Fertigungseinrichtungen, described before a description of the systems in particular classes of organism. The organisms are treated in the sequence: prokaryotes, single-cell eukaryotes and, lastly, multicellular organisms reaching up to man. The importance of local homeostasis in compartments contributing to the whole flow作者: Solace 時間: 2025-3-26 09:54
https://doi.org/10.1007/978-3-642-87673-8and is about thirty amino acids long and consists of an α-helix (.), loop, and second α-helix (F). Usually a Ca. ion is bound in the loop under physiological conditions; however, 30% of all known EF-hands do not bind calcium. With only a few exceptions all EF-hand-containing proteins are found in th作者: 相反放置 時間: 2025-3-26 15:59
https://doi.org/10.1007/978-3-642-87673-8sphatases, and ion transporters. During the past decade, three-dimensional structures of calmodulin in forms of various target complexes have been elucidated. This review presents the latest advances in the field of calmodulin and its target proteins, with particular emphasis on the structural basis作者: 無法取消 時間: 2025-3-26 18:08
,Steuersysteme für Fertigungseinrichtungen,a number of inherited diseases caused by missense mutations within the domain. It is characterised by six cysteine residues which normally disulphide bond in a 1–3, 2–4, 5–6 pattern and a calcium-binding consensus D/N-x-D/N-E/Q-x.-D/ N*-x.-Y/F (where m and n are variables and * indicates possible β-作者: 改變立場 時間: 2025-3-26 21:29
https://doi.org/10.1007/978-3-642-81964-3ependent on changes of the intracellular concentrations of the second messenger Ca.. In this chapter the structural and functional properties of CaMkinases are summarized. The different kinases known to date can be either monospecific for one substrate or multifunctional, recognizing a number of dif作者: 解決 時間: 2025-3-27 02:21
https://doi.org/10.1007/978-3-642-81964-3d a major problem in biology at the molecular level: how are external signals acting on plasma membrane receptors transmitted to the nucleus. The specific inhibition by immunosuppressive drugs, complexed with their binding proteins, of the Ca./ calmodulin-dependent protein phosphatase, calcineurin, 作者: 鋪子 時間: 2025-3-27 06:32
https://doi.org/10.1007/978-3-642-81964-3sport across intracellular membranes. Coupling of ATP hydrolysis and Ca. transport is based on an intramolecular long-range linkage between ATP hydrolysis within the cytosolic region, and vectorial displacement of bound Ca. within the membrane-bound region of the ATPase. Equilibrium and kinetic meas作者: Lobotomy 時間: 2025-3-27 12:24
https://doi.org/10.1007/978-3-642-81964-3 has been found not only in all mammalian cells, but also in varieties of invertebrates and in yeast. So far no PMCA genes have been found in bacteria. The biochemical and biophysical properties of the pump have been primarily studied on the enzyme purified from the membrane of the red blood cells b作者: exacerbate 時間: 2025-3-27 16:40
https://doi.org/10.1007/978-3-642-81964-3ularly important to excitable tissues. Three homologous exchanger gene products (NCX1, 2, 3) are differently expressed in heart, brain and kidney. Hydropathy analysis has indicated 11 hydrophobic segments with highly conserved regions that have been suggested to play a role in ion transport (α-repea作者: 土產 時間: 2025-3-27 21:03
Calcium Homeostasis978-3-642-58306-3Series ISSN 1437-7993 作者: amenity 時間: 2025-3-27 23:18
Calcium Homeostasis and Its Evolution, described before a description of the systems in particular classes of organism. The organisms are treated in the sequence: prokaryotes, single-cell eukaryotes and, lastly, multicellular organisms reaching up to man. The importance of local homeostasis in compartments contributing to the whole flow作者: Excitotoxin 時間: 2025-3-28 06:09 作者: 大量殺死 時間: 2025-3-28 09:48 作者: 祖?zhèn)?nbsp; 時間: 2025-3-28 11:32
Calcium-Binding EGF-like Domains,a number of inherited diseases caused by missense mutations within the domain. It is characterised by six cysteine residues which normally disulphide bond in a 1–3, 2–4, 5–6 pattern and a calcium-binding consensus D/N-x-D/N-E/Q-x.-D/ N*-x.-Y/F (where m and n are variables and * indicates possible β-作者: Atheroma 時間: 2025-3-28 15:46
Calmodulin-Dependent Protein Kinases,ependent on changes of the intracellular concentrations of the second messenger Ca.. In this chapter the structural and functional properties of CaMkinases are summarized. The different kinases known to date can be either monospecific for one substrate or multifunctional, recognizing a number of dif