標(biāo)題: Titlebook: CCN proteins in health and disease; An overview of the F Annick Perbal,Masaharu Takigawa,Bernard Perbal Book 2010 Springer Science+Business [打印本頁] 作者: AMASS 時間: 2025-3-21 19:38
書目名稱CCN proteins in health and disease影響因子(影響力)
書目名稱CCN proteins in health and disease影響因子(影響力)學(xué)科排名
書目名稱CCN proteins in health and disease網(wǎng)絡(luò)公開度
書目名稱CCN proteins in health and disease網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱CCN proteins in health and disease被引頻次
書目名稱CCN proteins in health and disease被引頻次學(xué)科排名
書目名稱CCN proteins in health and disease年度引用
書目名稱CCN proteins in health and disease年度引用學(xué)科排名
書目名稱CCN proteins in health and disease讀者反饋
書目名稱CCN proteins in health and disease讀者反饋學(xué)科排名
作者: Anhydrous 時間: 2025-3-21 21:52
Asking the Right Questions: What Can the Structure of the CCN Protein Domains Tell Us?, a CT domain. These domains give a broad repertoire of functions to the CCN family including angiogenesis, skeletal development tumourigenesis, wound healing, cell proliferation, adhesion and survival. These wide variety of biological functions are enabled due to the multi-domain nature of the prote作者: Orchiectomy 時間: 2025-3-22 03:37
Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of , mRNA, of . is tightly regulated to confer a maximal level at prehypertrophic – hypertrophic stages, in which the 3‘-untranslated region (UTR) of the mRNA is critically involved in mediating its post-transcriptional regulation. In our previous studies, we found that a 40-kDa protein binding specifically t作者: obeisance 時間: 2025-3-22 05:17
,The CCN Genes as the “Master” Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Difand pathological states and for engineering functional tissue constructs in vitro. Similarly, embryonic and fetal development of a variety of tissues is, at least in part, orchestrated by mechanical cues although such influence is seldom acknowledged because it is difficult to elaborate experimental作者: Strength 時間: 2025-3-22 11:07 作者: 做方舟 時間: 2025-3-22 15:47 作者: 做方舟 時間: 2025-3-22 19:24 作者: Granular 時間: 2025-3-22 22:23 作者: 錫箔紙 時間: 2025-3-23 04:27
Role of Connective Tissue Growth Factor in Cardiac Fibrosis,triggered by a number of signaling pathways that result in excessive production and deposition of extracellular matrix (ECM). Connective Tissue Growth factor (CTGF, CCN2), a member of CCN (.yr61, .tgf, .ov) family, is a multifunctional protein that is expressed in both cardiac myocytes and fibroblas作者: 最有利 時間: 2025-3-23 08:43
Gene Expression of CCN Family Members in Young and Aged Human Skin In Vivo,tracellular matrix production. Altered expression of CCN family members are associated with several pathological states, including tissue fibrosis, inflammation, and cancer. We have previously reported that CCN1 and CCN2 are predominantly expressed in dermal fibroblasts, and are involved in aberrant作者: Visual-Field 時間: 2025-3-23 13:19
Global Expression Profiling Reveals a Role for CTGF/CCN2 in Lactogenic Differentiation of Mouse Mamand apoptosis. HC11 mouse mammary epithelial cells, which are capable of lactogen-induced differentiation in cell culture, were used to follow the changes in gene expression during this process. The expression profiles of over 20,000 genes were compared in HC11 cells undergoing lactogenic differenti作者: 摘要 時間: 2025-3-23 16:38 作者: faucet 時間: 2025-3-23 19:05
Inhibitors of Connective Tissue Growth Factor (CCN2)-Mediated Fibrogenesis: Underlying Mechanisms aeam of transforming growth factor beta (TGF-β)-mediated intracellular signaling. In recent years the role of CCN2 in fibrogenic pathways has been explored by experimentally attenuating its production or action through the use of pharmacological inhibitors, neutralizing antibodies, antisense oligonuc作者: condescend 時間: 2025-3-24 00:32 作者: 表否定 時間: 2025-3-24 02:31 作者: 抗原 時間: 2025-3-24 08:58
CCN6 Regulates Breast Cancer Growth and Invasion Through Modulation of IGF Signaling and Epithelialhomeostatic biological processes. Matricellular proteins, which include the CCN family of proteins, have the ability to coordinate the extracellular and intracellular signaling pathways and thus modulate the cross-talk between the microenvironment, epithelial and mesenchymal cells. Our laboratory ha作者: 誹謗 時間: 2025-3-24 11:56 作者: 共同給與 時間: 2025-3-24 16:38 作者: 諷刺滑稽戲劇 時間: 2025-3-24 21:44
https://doi.org/10.1007/978-3-8350-5541-4CN2 gene transcription exclusively in tubular epithelial cells stimulated with TGF-β1. Although further studies are necessary, the regulatory PARP-1/PBE complex seems to be a promising target for anti-fibrotic therapy.作者: 使乳化 時間: 2025-3-24 23:32
Gunda Huskobla,Matthias Jakob,J?rg Neumannat CCN3 downregulates osteogenesis by two different pathways: suppression of BMP and stimulation of Notch. This effect was also transmitted to osteoblasts in separate cultures, which indicates the paracrine manner of CCN3 activity. CCN3 may also affect the extracellular environment of the niche for hematopoietic stem cells.作者: 射手座 時間: 2025-3-25 04:03 作者: biopsy 時間: 2025-3-25 10:23 作者: Cpap155 時間: 2025-3-25 14:01 作者: 雜色 時間: 2025-3-25 19:38
The Role of CCN3 in Mesenchymal Stem Cells,at CCN3 downregulates osteogenesis by two different pathways: suppression of BMP and stimulation of Notch. This effect was also transmitted to osteoblasts in separate cultures, which indicates the paracrine manner of CCN3 activity. CCN3 may also affect the extracellular environment of the niche for hematopoietic stem cells.作者: FLASK 時間: 2025-3-25 23:36
Inhibitors of Connective Tissue Growth Factor (CCN2)-Mediated Fibrogenesis: Underlying Mechanisms aut the mechanisms by which CCN2 production is regulated, have definitively established a role for CCN2 in contributing to fibrotic pathologies, and have provided proof of principle for targeting CCN2 as an anti-fibrotic strategy.作者: urethritis 時間: 2025-3-26 01:40 作者: Dorsal 時間: 2025-3-26 08:07
e., Cyr61/CCN1; ctgf/CCN2; Nov/CCN3; WISP1/CCN4; WISP2/CCN5, and WISP3/CCN6) showing a strikingly conserved primary structure, with four modules sharing partial identity with IGF binding proteins, Von Willebrand protein, thrombospondin and several matricellular proteins and growth factors. ..The cur作者: excursion 時間: 2025-3-26 09:32 作者: syring 時間: 2025-3-26 13:05 作者: palliate 時間: 2025-3-26 17:31
Anwendung in der Nachwuchsf?rderungin allowing interactions with an extensive range of ligands and effectors and the possibility of multiple domains acting in concert. A closer look at each domain from a biological and structural perspective could give insights into their function.作者: 過剩 時間: 2025-3-27 00:54
https://doi.org/10.1007/978-3-8350-5541-4n the CCN field to present and exchange ideas. The CCN family of regulatory proteins play key roles in both normal cell development and a wide range of pathologies. This was reflected in the breadth of basic cell biology and translational studies presented at the conference. Exciting new in vitro an作者: figure 時間: 2025-3-27 02:22 作者: PHAG 時間: 2025-3-27 06:44
Anwendung in der Nachwuchsf?rderung of . is tightly regulated to confer a maximal level at prehypertrophic – hypertrophic stages, in which the 3‘-untranslated region (UTR) of the mRNA is critically involved in mediating its post-transcriptional regulation. In our previous studies, we found that a 40-kDa protein binding specifically t作者: Left-Atrium 時間: 2025-3-27 09:49
Anwendung in der Nachwuchsf?rderungand pathological states and for engineering functional tissue constructs in vitro. Similarly, embryonic and fetal development of a variety of tissues is, at least in part, orchestrated by mechanical cues although such influence is seldom acknowledged because it is difficult to elaborate experimental作者: 上流社會 時間: 2025-3-27 16:58 作者: AVID 時間: 2025-3-27 20:05 作者: 劇本 時間: 2025-3-27 22:56 作者: Acclaim 時間: 2025-3-28 05:56 作者: 圓柱 時間: 2025-3-28 08:00
https://doi.org/10.1007/978-3-642-41257-8triggered by a number of signaling pathways that result in excessive production and deposition of extracellular matrix (ECM). Connective Tissue Growth factor (CTGF, CCN2), a member of CCN (.yr61, .tgf, .ov) family, is a multifunctional protein that is expressed in both cardiac myocytes and fibroblas作者: RALES 時間: 2025-3-28 12:43 作者: 易受刺激 時間: 2025-3-28 18:04
Gunda Huskobla,Matthias Jakob,J?rg Neumannand apoptosis. HC11 mouse mammary epithelial cells, which are capable of lactogen-induced differentiation in cell culture, were used to follow the changes in gene expression during this process. The expression profiles of over 20,000 genes were compared in HC11 cells undergoing lactogenic differenti作者: 發(fā)炎 時間: 2025-3-28 20:08 作者: Amenable 時間: 2025-3-29 02:43 作者: ETCH 時間: 2025-3-29 06:03
https://doi.org/10.1007/978-3-322-94188-6short-term cultures from 50 melanoma lesions revealed a heterogeneous expression of the 46?kDa full-length protein and the 32?kDa truncated form. In fact, some melanomas were negative for CCN3 expression, while others expressed both isoforms at the cellular level and secreted in the culture medium. 作者: 金絲雀 時間: 2025-3-29 08:53
https://doi.org/10.1007/978-3-476-02712-2ation between chromosomes 9 and 22 resulting in the production of the BCR-ABL protein tyrosine kinase. Expression of BCR-ABL in stem cells of the myeloid blood cell population has been shown to be directly responsible for malignant transformation. We identified down-regulation of the negative growth作者: BINGE 時間: 2025-3-29 15:01 作者: facetious 時間: 2025-3-29 17:31
Gunda Huskobla,Matthias Jakob,J?rg Neumannion of . and . gene expression by these two proteins. These findings point out the need for a more thorough investigation of functional interactions between CCN proteins in normal and pathological conditions作者: 向下 時間: 2025-3-29 20:25
Anwendung in der Nachwuchsf?rderungAs an introduction to the 2008 Toronto CCN meeting Proceedings, we provide in this chapter a brief discussion of new findings regarding the functional interactions of CCN2 and CCN3 that will certainly have an impact on our understanding of the functions of CCN proteins and the regulatory processes that control and govern their biological roles.作者: 新義 時間: 2025-3-30 02:38
A Recent Breakthrough in the CCN Field: Functional Interactions Between CCN2 and CCN3 are UncoveredAs an introduction to the 2008 Toronto CCN meeting Proceedings, we provide in this chapter a brief discussion of new findings regarding the functional interactions of CCN2 and CCN3 that will certainly have an impact on our understanding of the functions of CCN proteins and the regulatory processes that control and govern their biological roles.作者: 過渡時期 時間: 2025-3-30 05:49 作者: DUCE 時間: 2025-3-30 09:30
Annick Perbal,Masaharu Takigawa,Bernard PerbalUnique book volume on the 2008 CCN SOciety Conference作者: Bumptious 時間: 2025-3-30 16:04 作者: flammable 時間: 2025-3-30 18:21 作者: Mawkish 時間: 2025-3-30 22:10 作者: 大門在匯總 時間: 2025-3-31 01:14 作者: 離開真充足 時間: 2025-3-31 05:01
,The CCN Genes as the “Master” Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Difthat regulate the expression of numerous fetal genes including a subset of inducible ECM-associated proteins referred to as Cysteine-rich protein 61 (Cyr61 or CCN1) and connective tissue growth factor (CTGF or CCN2). CCN1 and CCN2 are structurally-related and functionally multifaceted multimodular p作者: 胎兒 時間: 2025-3-31 12:16
A Monoclonal Antibody Approach to CCN5 Domain Analysis,ions of individual domains of CCN5, we are developing domain-specific mouse monoclonal antibodies. Monoclonal antibodies have the advantages of great specificity, reproducibility, and ease of long-term storage and production. In this communication, we injected mixtures of GST-fused rat CCN5 domains 作者: PLAYS 時間: 2025-3-31 13:41
Role of Connective Tissue Growth Factor in Cardiac Fibrosis,ad. Recently, we have shown that KLF15 is a novel negative regulator of CTGF expression in the heart via its ability to counteract Smad signaling at the CTGF promoter. From a clinical standpoint, progress has been made in utilizing CTGF levels as a biomarker for fibrotic diseases. In this chapter, w
