標題: Titlebook: Biochemistry of Pulmonary Emphysema; C. Grassi,J. Travis,M. Luisetti Book 1992 Springer-Verlag London 1992 Alpha1-Proteinase Inhibitor.Lun [打印本頁] 作者: LH941 時間: 2025-3-21 17:09
書目名稱Biochemistry of Pulmonary Emphysema影響因子(影響力)
書目名稱Biochemistry of Pulmonary Emphysema影響因子(影響力)學科排名
書目名稱Biochemistry of Pulmonary Emphysema網絡公開度
書目名稱Biochemistry of Pulmonary Emphysema網絡公開度學科排名
書目名稱Biochemistry of Pulmonary Emphysema被引頻次
書目名稱Biochemistry of Pulmonary Emphysema被引頻次學科排名
書目名稱Biochemistry of Pulmonary Emphysema年度引用
書目名稱Biochemistry of Pulmonary Emphysema年度引用學科排名
書目名稱Biochemistry of Pulmonary Emphysema讀者反饋
書目名稱Biochemistry of Pulmonary Emphysema讀者反饋學科排名
作者: 亞當心理陰影 時間: 2025-3-21 22:49
Synthetic Mechanism-Based and Transition-State Inhibitors for Human Neutrophil Elastase,old in the lungs of smokers and it is postulated that α.PI is inactivated by powerful oxidizing agents in the cigarette smoke and PMNs contributing to the elastase-antielastase imbalance. Other proteases including human proteinase 3 and macrophage elastase may also play a role in lung destruction in作者: 合并 時間: 2025-3-22 00:53 作者: 全等 時間: 2025-3-22 06:18 作者: 反話 時間: 2025-3-22 09:38 作者: JIBE 時間: 2025-3-22 15:15
Genetic Control of Human Alpha-1-Antitrypsin and Hepatic Gene Therapy,sin, thrombin, kallikrein, and plasmin., its apparent major physiological role is to diffuse into the alveoli structure of the lung, and protect elastin fibres from excessive hydrolysis by neutrophil elastase.. Neutrophil elastase is inhibited by forming a pseudo-irreversible equimolar complex of the protease with inhibitor..作者: 徹底明白 時間: 2025-3-22 17:30
Book 1992ral inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing proper enzyme-inhibitor balance, including the use of natural or synthetic inhibitors for supplementation or gene therapy.作者: 半圓鑿 時間: 2025-3-22 23:43 作者: escalate 時間: 2025-3-23 02:04
Kostenrechnung in Klein- und Mittelbetriebenal and venous elements, lymphatics, and the pleura. The unusual hydrophobic properties of the protein, together with the presence of numerous intermolecular crosslinks, in particular desmosine and isodesmosine, produce a highly insoluble, durable network of polypeptide chains that function as a perfect elastomer in an aqueous environment.作者: 誘騙 時間: 2025-3-23 06:42 作者: Ptsd429 時間: 2025-3-23 09:43
Book 1992 neurophils during phagocytosis at inflammatory foci within the lung. This volume not only reviews at a biochemical level what is known about the natural inhibitors and proteinases involved in connective tissue destruction within the lung, but also suggests novel methodologies for reestablishing pro作者: 其他 時間: 2025-3-23 16:08 作者: 新娘 時間: 2025-3-23 20:16 作者: 概觀 時間: 2025-3-23 22:29
https://doi.org/10.1007/978-3-663-14764-0mainly from the observation that heritable severe deficiency of α.-proteinase inhibitor (α.PI) is associated with development of the disease at a relatively young age. α.PI, present in alveolar airspaces as a transudated protein from the circulation, plays an important role in the regulation of neutrophil elastase activity.作者: Eeg332 時間: 2025-3-24 04:08 作者: stratum-corneum 時間: 2025-3-24 06:48
,Pulmonary Emphysema: What’s Going On,ment of these chronic disorders, and has assumed alarming proportions during the past fifty years. A few figures convey the magnitude of the problem: in the USA, COPD was responsible in 1987 for 354,000 hospitalizations and 74,000 deaths.作者: penance 時間: 2025-3-24 10:43 作者: 擔憂 時間: 2025-3-24 17:19
Development and Evaluation of Antiproteases as Drugs for Preventing Emphysema,istory, age and the level of ventilatory function as measured by the forced expiratory volume for 1 sec (FEV.).. About 15% of long term smokers are at risk of developing chronic obstructive pulmonary disease (COPD)..作者: 羊欄 時間: 2025-3-24 20:32
https://doi.org/10.1007/978-3-663-13230-1however, to offset the possibility of protei-nase damage the body offers a series of inhibitors, primarily plasma derived, which function to specifically inactivate these enzymes. In particular, it is now known that human plasma α. proteinase inhibitor (α.PI) regulates the activity of HNE while cat G is controlled by α. antichymotrypsin (α.Achy)..作者: insidious 時間: 2025-3-25 00:37 作者: 苦澀 時間: 2025-3-25 04:11 作者: heckle 時間: 2025-3-25 08:51
Neutrophils, Neutrophil Elastase and the Fragile Lung: The Pathogenesis and Therapeutic Strategies serine protease capable of destroying most components of the extracellular matrix of the alveolar walls.. In addition, NE can injure the bronchial epithelium and interfere with respiratory host defence by altering mucociliary clearance mechanisms and interfering with the ability of inflammatory cells to kill microorganisms..作者: Apoptosis 時間: 2025-3-25 14:30
https://doi.org/10.1007/978-1-4471-3771-9Alpha1-Proteinase Inhibitor; Lungenemphysem; Lungenerkrankung; Proteinase Inhibitors; Proteinases; Pulmon作者: Visual-Acuity 時間: 2025-3-25 17:59
978-1-4471-3773-3Springer-Verlag London 1992作者: Leisureliness 時間: 2025-3-26 00:00
Current Topics in Rehabilitationhttp://image.papertrans.cn/b/image/186720.jpg作者: famine 時間: 2025-3-26 03:39
Kostenrechnung in der Chemischen IndustrieIt is commonly acknowledged that neutrophil elastase (NE) is responsible for lung elastin degradation that leads to emphysema.作者: 信條 時間: 2025-3-26 06:23 作者: 一瞥 時間: 2025-3-26 09:46 作者: conquer 時間: 2025-3-26 12:49
Lung Proteinases and Emphysema,It is commonly acknowledged that neutrophil elastase (NE) is responsible for lung elastin degradation that leads to emphysema.作者: 樹上結蜜糖 時間: 2025-3-26 20:36 作者: 只有 時間: 2025-3-26 21:42 作者: 以煙熏消毒 時間: 2025-3-27 04:10 作者: medieval 時間: 2025-3-27 05:33
Proteinases and Proteinase Inhibitors in the Pathogenesis of Pulmonary Emphysema in Humans, with the ability to digest this connective tissue and the inhibitors which protect it. This assumption forms the basis of the proteinase/antiproteinase theory of the pathogenesis of emphysema which has dominated the field of emphysema research for more than 25 years.作者: Conflagration 時間: 2025-3-27 10:42 作者: 可互換 時間: 2025-3-27 14:09 作者: Outspoken 時間: 2025-3-27 20:51
Begriff der Chemischen Industrieal and pathological processes. A concept that has proved helpful in this is that of splitting the enzymes into groups on the basis of (a) the type of reaction that they catalyse and (b) the chemical mechanism of catalysis that they use.作者: 配偶 時間: 2025-3-27 21:55
Begriff der Chemischen Industrie with the ability to digest this connective tissue and the inhibitors which protect it. This assumption forms the basis of the proteinase/antiproteinase theory of the pathogenesis of emphysema which has dominated the field of emphysema research for more than 25 years.作者: nostrum 時間: 2025-3-28 05:42
https://doi.org/10.1007/978-3-663-13230-1egrading foreign and damaged human proteins. As a consequence of these processes significant quantities of neutrophil proteins are released extracellularly, both through cell leakage and cell death. This places a heavy burden on normal, healthy tissues which may now become susceptible to attack by n作者: configuration 時間: 2025-3-28 08:28 作者: 處理 時間: 2025-3-28 11:31
https://doi.org/10.1007/978-3-663-14764-0ivity in the peripheral lung due to a local imbalance between neutrophil elastase and the antineutrophil elastase screen.. This hypothesis has arisen mainly from the observation that heritable severe deficiency of α.-proteinase inhibitor (α.PI) is associated with development of the disease at a rela作者: 無辜 時間: 2025-3-28 15:11
Kostenrechnung in der Industriee USA, COPD caused more than 70,000 deaths in 1986 and more than 10,000,000 Americans suffered from the disease.. The association between severe α.protease inhibitor (α.PI) deficiency and emphysema has led to the hypothesis that an elastase-antielastase imbalance causes emphysema.. Human neutrophil 作者: Agility 時間: 2025-3-28 20:51 作者: 寬容 時間: 2025-3-29 01:37
Christian Ernst,Gerald Schenk,Peter Schuster% of the total protease inhibitory capacity in normal human serum.. In common with other members of the serine protease inhibitor superfamily,. the active inhibitory site of AAT is centred. around Ser.. Although it exhibits the capacity to inhibit a variety of proteases, including trypsin, chymotryp作者: 嚴厲批評 時間: 2025-3-29 05:00
https://doi.org/10.1007/978-3-662-53508-0nic and organic particulates, gases, fumes and aerosols. To help defend itself, the lung has available a variety of mechanisms that can recruit inflammatory cells, particularly blood neutrophils. However while effective in killing microorganisms, the neutrophil is a dangerous “two-edged sword”, with作者: nonradioactive 時間: 2025-3-29 10:09 作者: Phenothiazines 時間: 2025-3-29 13:22 作者: conspicuous 時間: 2025-3-29 19:09 作者: 色情 時間: 2025-3-29 23:48 作者: 十字架 時間: 2025-3-30 00:16
Elastin and the Lung, is the principal component of the elastic fibre, which is a composite of the amorphous elastic protein and one or more microfibrillar components. Elastic fibres provide resiliency to numerous pulmonary structures including the alveolar wall, the bronchiolar interstitium, the medial layers of arteri作者: Foreknowledge 時間: 2025-3-30 06:14 作者: 高爾夫 時間: 2025-3-30 08:51
Proteinases and Proteinase Inhibitors in the Pathogenesis of Pulmonary Emphysema in Humans, with the ability to digest this connective tissue and the inhibitors which protect it. This assumption forms the basis of the proteinase/antiproteinase theory of the pathogenesis of emphysema which has dominated the field of emphysema research for more than 25 years.作者: 拱形面包 時間: 2025-3-30 16:21
Multiple Functions of Neutrophil Proteinases and their Inhibitor Complexes,egrading foreign and damaged human proteins. As a consequence of these processes significant quantities of neutrophil proteins are released extracellularly, both through cell leakage and cell death. This places a heavy burden on normal, healthy tissues which may now become susceptible to attack by n作者: 難理解 時間: 2025-3-30 19:14
