標(biāo)題: Titlebook: Autoimmune Thyroiditis; Approaches Towards i W. A. Scherbaum,U. Bogner,G. F. Bottazzo Conference proceedings 1991 Springer-Verlag Berlin He [打印本頁] 作者: 召喚 時(shí)間: 2025-3-21 18:36
書目名稱Autoimmune Thyroiditis影響因子(影響力)
作者: 女上癮 時(shí)間: 2025-3-21 20:40
Thyroid Antibodies and Thyroid Dysfunction in Patients with Type 1 Diabetes and Their First-Degree Rassociated with other endocrine autoimmune disturbances. To the description of Schmidt’s syndrome [1], consisting originally of autoimmune thyroiditis and adrenalitis, diabetes was later added as third component. While the underlying genetic contribution in type 1 diabetes is closely related to clas作者: 令人作嘔 時(shí)間: 2025-3-22 02:52 作者: reject 時(shí)間: 2025-3-22 06:35 作者: carotid-bruit 時(shí)間: 2025-3-22 09:11
A Search for Linkage Between Phenylthiocarbamide Tasting, the Kell Blood Group Locus and Autoantibodhyroid disease, it was recently demonstrated that the inheritance of TPO and Tg autoantibodies was consistent with Mendelian inheritance [1]. The tendency to produce TPO and Tg autoantibodies appeared to be inherited as an autosomal dominant trait fully penetrant in women but with reduced penetrance作者: expdient 時(shí)間: 2025-3-22 16:14 作者: 捕鯨魚叉 時(shí)間: 2025-3-22 18:25
The Genetic Control of Thyroid Cell MHC Class II Antigen Expressionatibility complex (MHC). These antigens are recognized by syngeneic T cells expressing CD 8 antigen. The T cell receptor of the thyroid-specific CD 8. T cell combines with the MHC class I antigen, which encloses a thyroid-specific antigen within a well-defined cleft, to initiate cytolysis of the thy作者: ATP861 時(shí)間: 2025-3-22 21:18 作者: Arthritis 時(shí)間: 2025-3-23 02:06
Comparison Between Microsomal Antibodies by Immunofluorescence and Anti-TPO Antibodies in Healthy Ins for clinical measurement of autoantibodies to TPO (anti-TPO) have been developed [3,4]. We have therefore found it of interest to investigate the clinical usefulness of replacing measurements of MAb by a commercial method for quantifying anti-TPO. Furthermore, we wanted to compare the anti-TPO mea作者: 使乳化 時(shí)間: 2025-3-23 08:52 作者: 無可爭辯 時(shí)間: 2025-3-23 13:32
Comparison of New and Conventional Assay Techniques for Measuring Thyroid Microsomal Antibodiest which those antibodies are directed has only recently been identified and appears to be closely related to or identical with thyroid peroxidase (TPO) [2–5]. These advances in defining the microsomal antigen offer a chance to develop new assay techniques for measuring MAb. Hence, new assays rely on作者: pulmonary 時(shí)間: 2025-3-23 17:16
Further Clarification of the Significance of Thyroid Peroxidase Activity-Inhibiting Immunoglobulins xidase (TPO) [1–3], which catalyzes the synthesis of thyroid hormone. We have reported [4] that some anti-TPO antibodies inhibit the activity of TPO in vitro, and that these TPO activity-inhibiting immunoglobulins (TPII) seem to inhibit thyroid function in some patients, but the relationship between作者: 連詞 時(shí)間: 2025-3-23 18:02
Biochemical Dissection of the Reactivity of TPO Antibodies, and the microsomal antigens (MAg) is well established. The MAg is a glycoprotein of an apparent molecular weight of about 100kDa [1–3], and its major antigenic component is thyroid peroxidase (TPO) [4–7]. Recently published studies have suggested a heterogeneous nature of autoantibodies directed a作者: 種類 時(shí)間: 2025-3-24 00:37
T Cell Epitopes and Thyroid Peroxidasedes whereas T cells recognize short, lenear amino acid sequences of denatured antigen in association with MHC molecules. Further, detailed analyses of peptides stimulatory for T cells have indicated that such T cell “epitopes” have characteristic patterns of amino acids which may be predicted accord作者: Coeval 時(shí)間: 2025-3-24 02:51
Thyroid Microsome/Thyroid Peroxidase Autoantigenic Epitopes Recognized by Autoantibodies Map to the ase activity [1]. Although their precise role in the aetiology of AITD remains speculative, considerable evidence has accumulated to the effect that aAbs to the thyroid microsome/thyroid peroxidase antigen (TMA/TPO) may be pathogenetic [2]. TPO is a well-characterized enzyme involved in the generati作者: Culmination 時(shí)間: 2025-3-24 09:45
Comparison of Circulating Thyroid Microsomal, Cytotoxic and Thyroid Peroxidase Antibodiesmmune thyroid disease and have been thought to be implicated in thyroid cell damage observed in autoimmune thyroiditis. In support of this concept, antibodies that are cytotoxic for thyroid cells in vitro have been found in the sera of patients with autoimmune thyroiditis and exhibiting antimicrosom作者: 食道 時(shí)間: 2025-3-24 12:56 作者: arthroscopy 時(shí)間: 2025-3-24 17:03 作者: Cuisine 時(shí)間: 2025-3-24 20:27 作者: Nausea 時(shí)間: 2025-3-24 23:15 作者: chapel 時(shí)間: 2025-3-25 04:53
https://doi.org/10.1007/978-3-663-13372-8s have indicated that these T-cells are activated [5]. Further evidence for the immunological origin of IDDM came from the presence of anti-islet cell antibodies (ICA) in a diabetic’s sera [6] and from the success of immunosuppression in increasing remissions in newly diagnosed patients [7,8].作者: Priapism 時(shí)間: 2025-3-25 07:45 作者: STING 時(shí)間: 2025-3-25 12:32 作者: dearth 時(shí)間: 2025-3-25 16:07
Comparison of New and Conventional Assay Techniques for Measuring Thyroid Microsomal Antibodies a conventional hemagglutination test (HAT), which measures MAb reaction with a crude thyroid microsomal preparation; (b) Western blot analysis, which shows the reaction of MAb with distinct microsomal proteins; and (c) anti-TPO radioimmunoassay, which determines the reaction of MAb with purified human TPO.作者: 有惡臭 時(shí)間: 2025-3-25 21:30
Conference proceedings 1991 information given in textbooks is outdated. This is an important update for researchers who are interested in the above topics and in understanding the etiology and pathogenesis of thyroid autoimmunity.作者: 雕鏤 時(shí)間: 2025-3-26 02:20
Schriftenreihe Besteuerung der Unternehmung a good candidate. This overlap of different autoimmune diseases has led to the concept of polyendocrinopathy [4, 5], with the clinical or subclinical involvement of several organs in the same subject or family.作者: eulogize 時(shí)間: 2025-3-26 05:06
https://doi.org/10.1007/978-3-642-49213-6in relatives of patients with insulin-dependent diabetes mellitus (IDDM); these relatives show an association with the HLA specificity DR5 [3]. The disease itself has been shown to be associated with the HLA specificity DR5 in its hypertrophic form, with DR3 in its atrophic form and also with DR4 (reviewed in [4]).作者: babble 時(shí)間: 2025-3-26 11:35 作者: 墻壁 時(shí)間: 2025-3-26 13:15
Insulin and the Placenta in GDMtoimmune thyroiditis [2,3]. In such a situation the thyroid epithelial cell acts as an antigen-presenting cell, and such presentation is prevented by antibodies to MHC class I antigens (MHC restriction).作者: Cardiac 時(shí)間: 2025-3-26 18:11
Tumor-Like Trophoblastic Conditions,rtant question of whether the antigenic determinants of TPO include its catalytic sites is presently controversial, since another study failed to find any inhibition of TPO activity by anti-TPO-Abs [4].作者: 引起痛苦 時(shí)間: 2025-3-26 22:42 作者: ABYSS 時(shí)間: 2025-3-27 02:21 作者: enumaerate 時(shí)間: 2025-3-27 07:03 作者: isotope 時(shí)間: 2025-3-27 11:14 作者: 不規(guī)則的跳動(dòng) 時(shí)間: 2025-3-27 17:34
Biochemical Dissection of the Reactivity of TPO Antibodiesrtant question of whether the antigenic determinants of TPO include its catalytic sites is presently controversial, since another study failed to find any inhibition of TPO activity by anti-TPO-Abs [4].作者: 生來 時(shí)間: 2025-3-27 17:46
n this field review recent data from four subject areas: immunogenetics, thyroid peroxidase as an antigen, environmental factors, and cytokines. Much ongoing and as yet unpublished work is described, especially in the discussion included after each article. This information is of particular interest作者: 偽善 時(shí)間: 2025-3-28 01:05 作者: Arroyo 時(shí)間: 2025-3-28 04:47
Burden of GDM in Developing Countriesinical usefulness of replacing measurements of MAb by a commercial method for quantifying anti-TPO. Furthermore, we wanted to compare the anti-TPO measurements with an immunofluorescence method for MAb, which is generally considered rather specific.作者: Feature 時(shí)間: 2025-3-28 06:36
Tumor-Like Trophoblastic Conditions,n vitro, and that these TPO activity-inhibiting immunoglobulins (TPII) seem to inhibit thyroid function in some patients, but the relationship between TPII index and thyroid function is not simple. In this study, we examined whether TPII can inhibit the activity of TPO present in thyroid tissue.作者: 不真 時(shí)間: 2025-3-28 12:27
Donald P. Goldstein,Ross S. Berkowitztibodies that are cytotoxic for thyroid cells in vitro have been found in the sera of patients with autoimmune thyroiditis and exhibiting antimicrosomal antibodies. These cytotoxic antibodies are active both directly in the presence of complement [2, 3, 4] and in association with K cells [5].作者: 失望昨天 時(shí)間: 2025-3-28 18:21 作者: 預(yù)測(cè) 時(shí)間: 2025-3-28 18:51
Comparison Between Microsomal Antibodies by Immunofluorescence and Anti-TPO Antibodies in Healthy Ininical usefulness of replacing measurements of MAb by a commercial method for quantifying anti-TPO. Furthermore, we wanted to compare the anti-TPO measurements with an immunofluorescence method for MAb, which is generally considered rather specific.作者: 哥哥噴涌而出 時(shí)間: 2025-3-29 00:53
Further Clarification of the Significance of Thyroid Peroxidase Activity-Inhibiting Immunoglobulins n vitro, and that these TPO activity-inhibiting immunoglobulins (TPII) seem to inhibit thyroid function in some patients, but the relationship between TPII index and thyroid function is not simple. In this study, we examined whether TPII can inhibit the activity of TPO present in thyroid tissue.作者: 古老 時(shí)間: 2025-3-29 06:28
Comparison of Circulating Thyroid Microsomal, Cytotoxic and Thyroid Peroxidase Antibodiestibodies that are cytotoxic for thyroid cells in vitro have been found in the sera of patients with autoimmune thyroiditis and exhibiting antimicrosomal antibodies. These cytotoxic antibodies are active both directly in the presence of complement [2, 3, 4] and in association with K cells [5].作者: 宿醉 時(shí)間: 2025-3-29 08:09
Donald P. Goldstein,Ross S. Berkowitzon of thyroid hormones from thyroglobulin and comprises a 105-kDa protein [3] which has recently been cloned [4]. Two forms of TPO cDNA have been reported, termed TPO-1 and TPO-2, with exon 10 coding for 57 amino acids is spliced from the coding sequence of the shorter TPO-2 cDNA [5].作者: wreathe 時(shí)間: 2025-3-29 11:32 作者: 要塞 時(shí)間: 2025-3-29 18:12 作者: manifestation 時(shí)間: 2025-3-29 19:49
https://doi.org/10.1007/978-3-642-49213-6mmunity, but also specific recognition by the T-cell receptor supplemented by helper factors is necessary for an immune response [2]. Since organ-specific autoimmune diseases are chronic diseases, it might he speculated that the helper factors (interleukins), which provide a positive feedback, play 作者: 詞匯記憶方法 時(shí)間: 2025-3-30 03:21
https://doi.org/10.1007/978-3-7091-8925-2n the blood group Kell and TPO autoantibody. Kell has been reported to be linked to the locus governing the ability to taste phenylthiocarbamide (PTC) [3] which in turn may be associated with certain forms of thyroid disease [4]. In order to explore further the genetic basis of autoimmune thyroid di作者: Conspiracy 時(shí)間: 2025-3-30 05:56
Catherine Kim,Assiamira Ferraraods (passive hemagglutination and radioligand assay) with a newly developed radioimmunoassay for anti-TPO antibodies using the inhibition of binding of labeled TPO to a solid-phase bound monoclonal antibody by autoantibodies [3].作者: 同來核對(duì) 時(shí)間: 2025-3-30 11:32
Association of HLA Class I and Class II Genes and Adrenal Steroid 21-Hydroxylase Gene with Subacute mmunity, but also specific recognition by the T-cell receptor supplemented by helper factors is necessary for an immune response [2]. Since organ-specific autoimmune diseases are chronic diseases, it might he speculated that the helper factors (interleukins), which provide a positive feedback, play 作者: semiskilled 時(shí)間: 2025-3-30 15:39
A Search for Linkage Between Phenylthiocarbamide Tasting, the Kell Blood Group Locus and Autoantibodn the blood group Kell and TPO autoantibody. Kell has been reported to be linked to the locus governing the ability to taste phenylthiocarbamide (PTC) [3] which in turn may be associated with certain forms of thyroid disease [4]. In order to explore further the genetic basis of autoimmune thyroid di作者: 施舍 時(shí)間: 2025-3-30 18:20 作者: 鳥籠 時(shí)間: 2025-3-31 00:04
https://doi.org/10.1007/978-3-663-13372-8 the insulin-producing beta cells of the islets of Langerhans [1,2]. The immunological pathogenesis of this disease was initially suggested by the presence of a mononuclear cell infiltration of the islets, “insulitis,” in patients who had died within a few days of the clinical onset of IDDM [3,4]. T作者: 充滿人 時(shí)間: 2025-3-31 04:06 作者: Ejaculate 時(shí)間: 2025-3-31 06:56 作者: Synthesize 時(shí)間: 2025-3-31 10:47
https://doi.org/10.1007/978-3-642-49213-6ted to Graves’ disease. Both diseases can be observed clustered in families [1]. Furthermore, some patients progress from Graves’ disease to Hashimoto’s thyroiditis, illustrating that both diseases are part of one spectrum of thyroid autoimmunity. Antibodies to microsomal antigen (thyroid peroxidase作者: 充足 時(shí)間: 2025-3-31 15:03 作者: TRAWL 時(shí)間: 2025-3-31 17:56 作者: 愛花花兒憤怒 時(shí)間: 2025-3-31 22:14
