標(biāo)題: Titlebook: Antiviral Drug Discovery and Development; Xinyong Liu,Peng Zhan,Vasanthanathan Poongavanam Book 2021 The Editor(s) (if applicable) and The [打印本頁] 作者: 游牧 時間: 2025-3-21 19:54
書目名稱Antiviral Drug Discovery and Development影響因子(影響力)
書目名稱Antiviral Drug Discovery and Development影響因子(影響力)學(xué)科排名
書目名稱Antiviral Drug Discovery and Development網(wǎng)絡(luò)公開度
書目名稱Antiviral Drug Discovery and Development網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Antiviral Drug Discovery and Development被引頻次
書目名稱Antiviral Drug Discovery and Development被引頻次學(xué)科排名
書目名稱Antiviral Drug Discovery and Development年度引用
書目名稱Antiviral Drug Discovery and Development年度引用學(xué)科排名
書目名稱Antiviral Drug Discovery and Development讀者反饋
書目名稱Antiviral Drug Discovery and Development讀者反饋學(xué)科排名
作者: Emg827 時間: 2025-3-21 20:47
An Update on Antiretroviral Therapy, efforts during the last 40?years have led to the approval of over 30 antiretroviral drugs and the introduction of combination therapies that have turned HIV infection into a chronic but manageable disease. In this chapter, we provide an update on current available drugs and treatments, as well as f作者: Mercurial 時間: 2025-3-22 01:14 作者: bronchiole 時間: 2025-3-22 07:48 作者: 殺菌劑 時間: 2025-3-22 12:14
Moving Fast Toward Hepatitis B Virus Elimination,(pegylated or non-pegylated). These treatments can control viral replication and improve survival; however, they do not eliminate the virus and therefore require long-term continued therapy. In addition, there are significant concerns about virus rebound on discontinuation of therapy and the develop作者: 進(jìn)步 時間: 2025-3-22 16:23
Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection,stage of HCV infection, 18–34% of individuals exhibit spontaneous clearance. However, the remaining 66–82% of infected individuals progress to chronic HCV infection and are at subsequent risk of progression to hepatic fibrosis, cirrhosis, and hepatocellular carcinoma (HCC). Chronic hepatitis C progr作者: byline 時間: 2025-3-22 18:15 作者: 漂亮 時間: 2025-3-22 23:38
Anti-Influenza Drug Discovery and Development: Targeting the Virus and Its Host by All Possible Mea prevention and treatment of influenza virus infection and disease. Today, the number of antiviral molecules approved for the treatment of influenza is relatively limited, and their use is threatened by the emergence of viral strains with resistance mutations. There is therefore a real need to expan作者: BIAS 時間: 2025-3-23 04:20 作者: 松軟無力 時間: 2025-3-23 07:11 作者: bifurcate 時間: 2025-3-23 10:55
Covalent Antiviral Agents,tically increased. Hence, there is a pressing need to design potent broad-spectrum antiviral agents to treat a variety of viral infections and overcome viral resistance. Covalent inhibitors have the potential to achieve both goals owing to their biochemical efficiency, prolonged duration of action, 作者: Aviary 時間: 2025-3-23 14:44
Safe-in-Man Broad Spectrum Antiviral Agents,als does not adequately allow for proper preparedness in the face of unknown future epidemics. In addition, drug developers lack the financial incentives to work on antiviral drug discovery, with most pharmaceutical companies choosing to focus on more profitable disease areas. Safe-in-man broad spec作者: 前兆 時間: 2025-3-23 22:05
Exploiting Ubiquitin Ligases for Induced Target Degradation as an Antiviral Strategy,tein that tags substrates with a single molecule or with a polyubiquitin chain. Monoubiquitination affects trafficking and signaling patterns of modified proteins. In contrast, polyubiquitination, particularly K48-linked polyubiquitination, targets the protein for degradation by the Ubiquitin-Protea作者: bourgeois 時間: 2025-3-24 00:06
https://doi.org/10.1007/978-981-16-0267-2Antiviral drugs; enzyme inhibitors; drug design; antiviral therapy; viral infections作者: Resign 時間: 2025-3-24 03:46 作者: SLAG 時間: 2025-3-24 08:32
Antiviral Drug Discovery and Development978-981-16-0267-2Series ISSN 0065-2598 Series E-ISSN 2214-8019 作者: nerve-sparing 時間: 2025-3-24 12:43 作者: 油膏 時間: 2025-3-24 15:05 作者: NIB 時間: 2025-3-24 20:38 作者: Host142 時間: 2025-3-25 00:32
https://doi.org/10.1007/978-3-319-02189-8 efforts during the last 40?years have led to the approval of over 30 antiretroviral drugs and the introduction of combination therapies that have turned HIV infection into a chronic but manageable disease. In this chapter, we provide an update on current available drugs and treatments, as well as f作者: HAVOC 時間: 2025-3-25 07:16 作者: Cholecystokinin 時間: 2025-3-25 09:21
Springer Series in Advanced Microelectronicsechanisms controlling HIV integration and transcription is needed. Here we provide an overview of recent advances in the field. Lens epithelium-derived growth factor p75 (LEDGF/p75), a transcriptional coactivator, tethers and targets the HIV integrase into transcriptionally active regions of the chr作者: Measured 時間: 2025-3-25 12:21 作者: Jocose 時間: 2025-3-25 17:04 作者: 不開心 時間: 2025-3-25 23:18 作者: follicle 時間: 2025-3-26 02:36
https://doi.org/10.1007/3-540-51465-1 prevention and treatment of influenza virus infection and disease. Today, the number of antiviral molecules approved for the treatment of influenza is relatively limited, and their use is threatened by the emergence of viral strains with resistance mutations. There is therefore a real need to expan作者: Psa617 時間: 2025-3-26 04:35
Electronic Distance Measurementdamage health care and generate havoc all over the world. Coronavirus can spread quickly from person to person causing high morbidity and mortality. Unfortunately, the antiviral armamentarium is insufficient to fight these infections. In this chapter, we provide a detailed summary of the current sit作者: Relinquish 時間: 2025-3-26 09:34 作者: Lyme-disease 時間: 2025-3-26 12:59 作者: 聽寫 時間: 2025-3-26 20:43
Principles and Applications of EDM,als does not adequately allow for proper preparedness in the face of unknown future epidemics. In addition, drug developers lack the financial incentives to work on antiviral drug discovery, with most pharmaceutical companies choosing to focus on more profitable disease areas. Safe-in-man broad spec作者: HALL 時間: 2025-3-26 21:23 作者: 逃避責(zé)任 時間: 2025-3-27 01:47 作者: Forsake 時間: 2025-3-27 05:18
https://doi.org/10.1007/978-3-030-80538-8has increased the cure rates to nearly 100%. DAA therapy is among the best examples of success in the fight against viral infections. DAAs have transformed HCV management and have opened the door for the global eradication of HCV.作者: 戲法 時間: 2025-3-27 11:43 作者: 佛刊 時間: 2025-3-27 13:43 作者: 外面 時間: 2025-3-27 17:46
Moving Fast Toward Hepatitis B Virus Elimination,-HBV drug development strategies. Many of them are already in clinical trial phase 1 or 2, while others with promising results are still in preclinical stages. As research intensifies, potential HBV curative therapies and modalities in the pipeline are now on the horizon.作者: 逢迎白雪 時間: 2025-3-27 23:06
Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection,has increased the cure rates to nearly 100%. DAA therapy is among the best examples of success in the fight against viral infections. DAAs have transformed HCV management and have opened the door for the global eradication of HCV.作者: 和諧 時間: 2025-3-28 03:22
Exploiting Ubiquitin Ligases for Induced Target Degradation as an Antiviral Strategy,the UPS to degrade antiviral cellular host factors. Finally, I describe how we can exploit the same proteolytic machinery to enable PROTACs (Proteolysis-Targeting Chimeras) to degrade essential viral proteins. Successful implementation of this modality will add to the arsenal of emerging antiviral t作者: collagen 時間: 2025-3-28 07:57 作者: 諂媚于人 時間: 2025-3-28 12:49
An Update on Antiretroviral Therapy,uture prospects towards reducing pill burden and developing long-acting drugs and novel antiretroviral therapies. In addition, we summarize efforts to cure HIV, including pharmaceutical strategies focused on the elimination of the virus.作者: agitate 時間: 2025-3-28 16:30
Phytoconstituents as Lead Compounds for Anti-Dengue Drug Discovery,hytoconstituents have better selectivity index supporting their safety profile for future development. However, in vivo studies supporting therapeutic potency for these active phytoconstituents are limited. There is a need for studies translating anti-dengue profile of active phytoconstituents to find successful anti-dengue compounds.作者: wangle 時間: 2025-3-28 19:30
https://doi.org/10.1007/3-540-51465-1nza virus infections, with a focus on both virus-targeting and host cell-targeting strategies. Novel antiviral strategies targeting other viral proteins or targeting the host cell, some of which are based on drug repurposing, may be used in combination to strengthen our therapeutic arsenal against this major pathogen.作者: 愚笨 時間: 2025-3-29 02:52
Electronic Distance Measurementdiscussed in this review include molecules targeting viral components (e.g., RNA polymerase inhibitors, entry inhibitors, or protease inhibitors), compounds interfering with virus-host interactions, and drugs identified in large screening assays, effective against coronavirus replication, but with an uncertain mechanism of action.作者: 有發(fā)明天才 時間: 2025-3-29 04:45 作者: Itinerant 時間: 2025-3-29 11:14 作者: integral 時間: 2025-3-29 11:42 作者: overture 時間: 2025-3-29 19:27
Covalent Antiviral Agents,n mechanisms of covalent inhibitors against severe acute respiratory syndrome coronavirus 2, dengue virus, enterovirus, hepatitis C virus, human immunodeficiency virus, and influenza viruses. We also discuss the application of in silico study in covalent inhibitor design.作者: 類似思想 時間: 2025-3-29 20:02 作者: Atmosphere 時間: 2025-3-30 02:40
https://doi.org/10.1007/978-3-319-02189-8uture prospects towards reducing pill burden and developing long-acting drugs and novel antiretroviral therapies. In addition, we summarize efforts to cure HIV, including pharmaceutical strategies focused on the elimination of the virus.作者: Explicate 時間: 2025-3-30 04:57
The lexical analysis of French,hytoconstituents have better selectivity index supporting their safety profile for future development. However, in vivo studies supporting therapeutic potency for these active phytoconstituents are limited. There is a need for studies translating anti-dengue profile of active phytoconstituents to find successful anti-dengue compounds.作者: needle 時間: 2025-3-30 09:30
Schema Evolution in the STAR Frameworkin hematopoietic stem cell transplant recipients. Other viral targets such as the protein kinase and the helicase-primase complex are also evaluated for the development of novel potent inhibitors against herpesviruses.作者: dithiolethione 時間: 2025-3-30 14:50
Functional Transformations of Signals,an insight into the binding characteristics of drugs at the active and allosteric sites of different targets and the importance of targeting allosteric sites for design of new-generation antiretrovirals to overcome complex and resistant forms of the virus has been reviewed.作者: KEGEL 時間: 2025-3-30 17:27 作者: fabricate 時間: 2025-3-30 23:14
Physical Laws and Units Related to EDM,e in the advanced clinical studies. In this book chapter, the peptide-based lead compounds and drugs available for treating various viral diseases and their advantages and disadvantages when compared to small molecules drugs are discussed.作者: Cirrhosis 時間: 2025-3-31 03:56
