標(biāo)題: Titlebook: Antiviral Drug Development; A Multidisciplinary Erik Clercq,Richard T. Walker Conference proceedings 1988 Plenum Press, New York 1988 anti [打印本頁] 作者: 閘門 時間: 2025-3-21 18:31
書目名稱Antiviral Drug Development影響因子(影響力)
書目名稱Antiviral Drug Development影響因子(影響力)學(xué)科排名
書目名稱Antiviral Drug Development網(wǎng)絡(luò)公開度
書目名稱Antiviral Drug Development網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Antiviral Drug Development被引頻次
書目名稱Antiviral Drug Development被引頻次學(xué)科排名
書目名稱Antiviral Drug Development年度引用
書目名稱Antiviral Drug Development年度引用學(xué)科排名
書目名稱Antiviral Drug Development讀者反饋
書目名稱Antiviral Drug Development讀者反饋學(xué)科排名
作者: amnesia 時間: 2025-3-21 21:59 作者: Chandelier 時間: 2025-3-22 00:46
Animal Models as Assay Systems for the Development of Antivirals,g pharmacodynamics can be correlated with inhibition of viral replication in target organs. Additionally, our understanding of the pathogenesis of many viral infections, the response of the host to infection and interaction between the infection, the host’s response, and a therapeutic agent has been作者: 煞費(fèi)苦心 時間: 2025-3-22 08:07
Introduction and Historical Overview,s been painfully slow. Nevertheless acyclovir and various prodrugs, as well as some other nucleoside analogues with potent anti-viral properties, have been discovered and will be discussed in other Chapters. The opportunities afforded by inhibiting virally-coded enzymes with nucleoside analogues are作者: originality 時間: 2025-3-22 10:55 作者: Coronary-Spasm 時間: 2025-3-22 14:30
John P. Perdew,Matthias Ernzerhofg pharmacodynamics can be correlated with inhibition of viral replication in target organs. Additionally, our understanding of the pathogenesis of many viral infections, the response of the host to infection and interaction between the infection, the host’s response, and a therapeutic agent has been作者: 籠子 時間: 2025-3-22 19:45 作者: GLOSS 時間: 2025-3-22 21:47
Properties of Molecular Defects,: an Introduction and Apology for the Slow Progress”. Today, I think we no longer have to apologise; progress is still very slow but as I hope to show, there are many reasons for this, some of which are outside the control of scientists and given the constraints, no one can reasonably expect progress to be any faster.作者: Confirm 時間: 2025-3-23 01:30 作者: 充足 時間: 2025-3-23 07:03 作者: Nefarious 時間: 2025-3-23 11:20
NATO Science Series A:http://image.papertrans.cn/a/image/158703.jpg作者: chisel 時間: 2025-3-23 17:04 作者: Respond 時間: 2025-3-23 19:23
Experimental Aspects of Antiviral Pharmacology,Experimental pharmacology of antiviral agents include:作者: 搬運(yùn)工 時間: 2025-3-24 00:38 作者: committed 時間: 2025-3-24 03:42 作者: Electrolysis 時間: 2025-3-24 10:15 作者: LATE 時間: 2025-3-24 10:40 作者: Exaggerate 時間: 2025-3-24 16:19 作者: 摘要 時間: 2025-3-24 21:02 作者: CLAIM 時間: 2025-3-25 00:07 作者: 軍火 時間: 2025-3-25 04:45 作者: Lipoma 時間: 2025-3-25 07:55 作者: 定點(diǎn) 時間: 2025-3-25 11:54
The European Public Sphere and the Internetr the prophylaxis and early treatment of influenza A virus infections, idoxuridine, trifluridine, vidarabine and acyclovir for the topical treatment of herpetic keratitis, acyclovir for the systemic (intravenous or peroral) treatment of herpes simplex virus (HSV) and varicella-zoster virus (VZV) inf作者: Delirium 時間: 2025-3-25 18:23 作者: Callus 時間: 2025-3-25 21:33
Electronic Density Functional Theoryshortcomings of this so-called . testing are obvious: substances which lack an effect on the viral replication cycle but, e.g., enhance antibody formation, improve nonspecific resistance, strengthen the interferon systems will not be detected by this method. Likewise, although so far only rarely des作者: Pericarditis 時間: 2025-3-26 03:24
John P. Perdew,Matthias Ernzerhofnot be understated. While tissue culture systems are of great value in determining if a new drug has activity against a particular virus, these systems should not be used as indicators or predictors of activity in humans. Only where suitable animal models are not available, should a compound be take作者: Hiatus 時間: 2025-3-26 04:57 作者: aptitude 時間: 2025-3-26 08:49
Rachel Y. W. Lau,Hilary J. Kahnral, it manifests itself as tissue immunity. That means that a tissue infected with a virus is resistent to infection with other types of viruses. This phenomenon was already described in the beginning of this century, not only between antigenically related viruses such as yellow fever viruses (1) a作者: inhumane 時間: 2025-3-26 13:24
Schema Evolution in the STAR Frameworkvents that are unique and to identify compounds that have the potential to interfere with these events. The available new antiviral agents have already impacted upon the treatment of several viral illnesses and more are under development. With the advent of compounds that interrupt or interfere with作者: PARA 時間: 2025-3-26 17:06
Communication in a Distributed Environmentreased knowledge on antiviral drugs, but more importantly, one of attitude. The prevailing skepticism of the past has given way to optimism and determination. This determination is partially due to recent successes in the field, but more likely results from the acquired immunodeficiency syndrome (AI作者: jet-lag 時間: 2025-3-27 00:09 作者: 不可接觸 時間: 2025-3-27 02:05 作者: GRAVE 時間: 2025-3-27 05:52
Robert C. Morrison,Robert G. Parrflected in a measurable difference in sensitivity between the mutant and parental strain. Such resistance has now been observed in widely divergent virus families to a variety of specific inhibitors; some important examples are summarised in Table 1.作者: Diaphragm 時間: 2025-3-27 12:27 作者: 以煙熏消毒 時間: 2025-3-27 13:58 作者: ANA 時間: 2025-3-27 17:58
Electronic Density Functional Theoryof the organism, absent in cell culture, are required to convert the drug into its effective form. Most of the time, however, the reverse is true, viz. more compounds do appear active in a cell culture system than will later be found useful in the organism (Buthala, 1965; Eggers, 1977b). I shall refer to this problem in a later section.作者: 獎牌 時間: 2025-3-28 01:26
Rachel Y. W. Lau,Hilary J. Kahnn equine encephalomyelitis virus on the other hand (4). Especially the latter indicates that a non-immune mechanism was responsible. Although the most simple explanation for tissue immunity is a direct interaction between the different viruses, it has been assumed for a long time that a non-viral agent was responsible for this effect (3,5).作者: 反省 時間: 2025-3-28 03:40
Molecular Targets for Selective Antiviral Chemotherapy,f herpetic encephalitis), ribavirin for the topical (aerosol) treatment of respiratory syncytial virus infection in infants, and retrovir (azidothymidine) for the systemic (intravenous or peroral) treatment of AIDS and AIDS-related complex (ARC)..作者: 埋葬 時間: 2025-3-28 08:52 作者: Enzyme 時間: 2025-3-28 10:52 作者: 討人喜歡 時間: 2025-3-28 17:52 作者: 熱情的我 時間: 2025-3-28 20:29
Kerstin Goos,Bernd Beckert,Ralf Lindner for herpesviral latency is provided by EBV. In cells latently infected with EBV we have known or at least inferred that different DNA polymerases are utilized in productive . latent infection, with only the virus-specified polymerase being susceptible to the action of any of the known antiviral drugs.作者: BALK 時間: 2025-3-29 00:46 作者: STIT 時間: 2025-3-29 04:11
Epstein-Barr Virus, for herpesviral latency is provided by EBV. In cells latently infected with EBV we have known or at least inferred that different DNA polymerases are utilized in productive . latent infection, with only the virus-specified polymerase being susceptible to the action of any of the known antiviral drugs.作者: 不法行為 時間: 2025-3-29 07:56
Electronic Defect States in Alkali Halidesor years may not be accompanied by symptoms, can eventually cause chronic degenerative diseases with fatal outcome. It is known that viruses cause certain cancers in animals and man. Successful treatment of viral diseases with antiviral agents requires interruption of virus multiplication by specific inhibition of viral enzymes.作者: 演講 時間: 2025-3-29 12:25
Schema Evolution in the STAR Framework events at the genomic level, questions have been raised regarding the safety of these compounds as well as the adequacy of the available test systems to evaluate safety. Just as the field of antiviral drug therapy is young and evolving, so too are the methods used to assess their associated risk.作者: 浮雕寶石 時間: 2025-3-29 15:36 作者: Lumbar-Stenosis 時間: 2025-3-29 20:02 作者: 花費(fèi) 時間: 2025-3-30 01:51
Antiviral Chemotherapy: An Introduction and Reasons for the Slow Progress, Particularly towards Rat: an Introduction and Apology for the Slow Progress”. Today, I think we no longer have to apologise; progress is still very slow but as I hope to show, there are many reasons for this, some of which are outside the control of scientists and given the constraints, no one can reasonably expect progres作者: Occlusion 時間: 2025-3-30 05:25
Design of Nucleoside Analogs as Potential Antiviral Agents,thin living cells, commandeering the host cell to synthesize viral proteins and viral nucleic acids followed by final assembly into new virion particles. Viral infection may vary in severity from mild and transitory infections to illnesses that terminate in death. Persistent viral infection, which f作者: 善于 時間: 2025-3-30 08:52
Design of Anti-Viral Agents Other than Nucleoside Analogues,is going to be much more difficult than the corresponding searches for anti-bacterial and anti-fungal substances. Having accepted this situation it is interesting to note that over the past ten years the only compounds to emerge as serious contenders for a place as commercially important anti-bacter作者: Criteria 時間: 2025-3-30 12:29 作者: minaret 時間: 2025-3-30 20:02 作者: 膽小懦夫 時間: 2025-3-30 22:07
