標題: Titlebook: Antimicrobial Drug Resistance; Mechanisms of Drug R Douglas L. Mayers Book 2009 Humana Press 2009 Drug.HIV.Handbook.Hepatitis.Malaria.Mayer [打印本頁] 作者: GERD847 時間: 2025-3-21 17:54
書目名稱Antimicrobial Drug Resistance影響因子(影響力)
書目名稱Antimicrobial Drug Resistance影響因子(影響力)學科排名
書目名稱Antimicrobial Drug Resistance網(wǎng)絡公開度
書目名稱Antimicrobial Drug Resistance網(wǎng)絡公開度學科排名
書目名稱Antimicrobial Drug Resistance被引頻次
書目名稱Antimicrobial Drug Resistance被引頻次學科排名
書目名稱Antimicrobial Drug Resistance年度引用
書目名稱Antimicrobial Drug Resistance年度引用學科排名
書目名稱Antimicrobial Drug Resistance讀者反饋
書目名稱Antimicrobial Drug Resistance讀者反饋學科排名
作者: 攝取 時間: 2025-3-22 00:05
https://doi.org/10.1007/978-981-13-3444-3d by a number of simple phenomena in antibiotic resistance. Variability is created by random mutation, and some of these variants (for instance those with a mutation in the antibiotic target) become resistant. These variants are selected by antibiotic use and consequently they increase the frequency作者: Supplement 時間: 2025-3-22 02:26 作者: 綠州 時間: 2025-3-22 07:37 作者: 反省 時間: 2025-3-22 10:34 作者: 為敵 時間: 2025-3-22 14:41
Solid State Physics Literature Guidese antimicrobial agents are emerging. Bacteria with this phenotype are designated multidrug-resistant (MDR) or pan-drug resistant (PDR) strains. What is the genetic basis of this remarkable survival skill? Are advantageous changes in the genome always random? Is antibiotic pressure the cause of growi作者: 有抱負者 時間: 2025-3-22 18:24
Saurav Z. K. Sajib,Rosalind Sadleirnd/or function of the microorganism. In order to do their job effectively, antimicrobial agents must interact with these targets in a manner that precludes the normal functioning of the target molecule. Moreover, their interactions with the target must be fairly specifi c, otherwise the potential fo作者: GULLY 時間: 2025-3-22 23:32 作者: Abrupt 時間: 2025-3-23 05:10 作者: Palatial 時間: 2025-3-23 07:54
J. L. Counil,M. Menvielle,J. L. Le Mouelibiotic therapy, and that an alternative drug must be used. In this chapter, we will concern ourselves with the growing number of bacterial infections in which antibiograms of the causative organism show sensitivity to standard antibiotics in readily attainable concentrations, but the infection fail作者: archetype 時間: 2025-3-23 12:35
Electrical Resistance of Metalsheir therapeutic use began with the introduction of benzylpenicillin (penicillin G) during World War II (1, 2), and continues with the development of newer cephalosporins and carbapenems for antibioticresistant infections. These agents act by inhibiting bacterial cell wall synthesis, as a result of 作者: HALO 時間: 2025-3-23 16:02
Pressure, Magnetic-Field, and Size Effects,an, the major constituent of the cell wall. The peptidoglycan, or murein, is a giant molecule, which forms a molecular mesh around the plasma membrane. Chains of tandemly repeated disaccharides form the glycan strands that are linked to each other by short peptide bridges. The discoveries of the PBP作者: 揭穿真相 時間: 2025-3-23 20:58
Electrical Resistivity of Thin Metal Films They are pseudo-polysaccharides containing amino sugars and can therefore be considered polycationic species for the purpose of understanding their biological interactions. Since they are highly positively charged at physiological pH values, they show high binding affi nity for nucleic acids, espec作者: Serenity 時間: 2025-3-24 00:36 作者: LEERY 時間: 2025-3-24 04:52
1.2.3 References for 1.2.1 and 1.2.2,cities. Examples of this include temafl oxacin, which was found to be associated with hypoglycemia and hemolytic-uremic syndrome and trovafl oxacin, found to be associated with severe hepatotoxicity (2, 3). Although serious adverse events following quinolone use are relatively rare, some that have b作者: Guaff豪情痛飲 時間: 2025-3-24 09:23 作者: PIZZA 時間: 2025-3-24 11:41
1.3.3 References for 1.3.1 and 1.3.2,aused by various anaerobic and microaerophilic bacteria (Bacteroides, Clostridia, Helicobacter) and parasites (Trichomonas, Giardia, Entamoeba). Other Gram-positive anaerobes (e.g., lactobacilli, propionobacterium acnes, majority of the periodontal pathogens, peptostreptococci) are known to be inher作者: Pessary 時間: 2025-3-24 18:44
Infectious Diseasehttp://image.papertrans.cn/a/image/158599.jpg作者: incubus 時間: 2025-3-24 21:10 作者: 雄辯 時間: 2025-3-25 00:22
Pharmacology of Drug Resistancence with respect to antibacterial agents (1). Therapy of human immunodefi ciency virus (HIV) is often restricted by multidrug resistance (2). Multidrugresistant TB is exploding in several areas of the world. Most of the discussion below will focus on bacteria, but the ideas are applicable to any pathogen.作者: 細菌等 時間: 2025-3-25 06:12
https://doi.org/10.1007/978-1-59745-180-2Drug; HIV; Handbook; Hepatitis; Malaria; Mayers; Resistance; Schistosomiasis; Virus; antibiotics; antimicrobia作者: 蝕刻 時間: 2025-3-25 09:24
1.2.3 References for 1.2.1 and 1.2.2,The structurally unrelated antimicrobials, macrolides, lincosamides, and streptogramins are grouped into a single family, the MLS family. This classifi cation is justifi ed by a similar, although not identical, mechanism of action.作者: HERTZ 時間: 2025-3-25 13:26 作者: Thyroxine 時間: 2025-3-25 16:30 作者: 逃避系列單詞 時間: 2025-3-25 23:43
Evolutionary Biology of Drug Resistanced by a number of simple phenomena in antibiotic resistance. Variability is created by random mutation, and some of these variants (for instance those with a mutation in the antibiotic target) become resistant. These variants are selected by antibiotic use and consequently they increase the frequency作者: Latency 時間: 2025-3-26 02:02 作者: Foreknowledge 時間: 2025-3-26 04:29 作者: 擦掉 時間: 2025-3-26 11:25 作者: NAVEN 時間: 2025-3-26 12:57
Mutations as a Basis of Antimicrobial Resistancee antimicrobial agents are emerging. Bacteria with this phenotype are designated multidrug-resistant (MDR) or pan-drug resistant (PDR) strains. What is the genetic basis of this remarkable survival skill? Are advantageous changes in the genome always random? Is antibiotic pressure the cause of growi作者: Diaphragm 時間: 2025-3-26 18:41
Target-Mediated Antibacterial Resistancend/or function of the microorganism. In order to do their job effectively, antimicrobial agents must interact with these targets in a manner that precludes the normal functioning of the target molecule. Moreover, their interactions with the target must be fairly specifi c, otherwise the potential fo作者: 模范 時間: 2025-3-26 23:45
Antibiotic Resistance Due to Reduced Uptake pre-antibiotic era. However, a disturbing trend has also been noted in that, within a very short period of time following the introduction of a new antibiotic, resistance to that antibiotic begins to emerge, a factor that is becoming increasingly meaningful as the discovery of new antibiotics wanes作者: sundowning 時間: 2025-3-27 01:07 作者: Obligatory 時間: 2025-3-27 08:43
The Functional Resistance of Bacterial Biofilmsibiotic therapy, and that an alternative drug must be used. In this chapter, we will concern ourselves with the growing number of bacterial infections in which antibiograms of the causative organism show sensitivity to standard antibiotics in readily attainable concentrations, but the infection fail作者: 幻影 時間: 2025-3-27 13:24
The Importance of β-Lactamases to the Development of New β-Lactamsheir therapeutic use began with the introduction of benzylpenicillin (penicillin G) during World War II (1, 2), and continues with the development of newer cephalosporins and carbapenems for antibioticresistant infections. These agents act by inhibiting bacterial cell wall synthesis, as a result of 作者: 不理會 時間: 2025-3-27 16:18 作者: tic-douloureux 時間: 2025-3-27 20:17
Aminoglycosides: Mechanisms of Action and Resistance They are pseudo-polysaccharides containing amino sugars and can therefore be considered polycationic species for the purpose of understanding their biological interactions. Since they are highly positively charged at physiological pH values, they show high binding affi nity for nucleic acids, espec作者: 卵石 時間: 2025-3-27 22:36 作者: collagen 時間: 2025-3-28 05:10 作者: NIB 時間: 2025-3-28 07:29 作者: chisel 時間: 2025-3-28 11:36
Mechanism of Resistance in Metronidazoleaused by various anaerobic and microaerophilic bacteria (Bacteroides, Clostridia, Helicobacter) and parasites (Trichomonas, Giardia, Entamoeba). Other Gram-positive anaerobes (e.g., lactobacilli, propionobacterium acnes, majority of the periodontal pathogens, peptostreptococci) are known to be inher作者: gorgeous 時間: 2025-3-28 15:45 作者: Adenocarcinoma 時間: 2025-3-28 18:50
en by individual microbial agents including bacteria, fungi, protozoa and viruses. Volume 2 addresses clinical, epidemiologic and public health aspects of drug resistance along with an overview of the conduct and interpretation of speci? c drug resistance assays. Together, these two volumes offer a comprehens978-1-62703-866-9978-1-59745-180-2作者: 懲罰 時間: 2025-3-29 00:17
Evolutionary Biology of Drug ResistanceThe acquisition of any type of resistance produces a change. In biology, any change is not only an opportunity, but is also a risk for evolution. Bacterial organisms are highly integrated functional structures, exquisitely tuned by evolutionary forces to fi t with their environments. Beyond the thre作者: Pde5-Inhibitors 時間: 2025-3-29 04:49
Antimicrobial Resistance Versus the Discovery and Development of New Antimicrobialsat in large pharmaceutical companies. Finally, we will speculate on the future of antibacterial discovery and development given the emerging trends in science, in the marketplace, within the regulatory environment, and in the context of the pharmaceutical business.作者: occurrence 時間: 2025-3-29 07:24
Genetic Mechanisms of Transfer of Drug Resistanceknown to be composed of the replication and transfer functions of the plasmids, and the genes in these studies are now known to be on mobile elements (simple and composite transposons and integrons). The 1960s and 1970s saw a rapid increase in the number of antibiotics (particularly aminoglycosides 作者: 聚集 時間: 2025-3-29 12:11 作者: 用肘 時間: 2025-3-29 18:35
Transport Mechanisms of Resistance to Drugs and Toxic Metalsugh some of these transporters extrude specifi c drugs and metals, others can extrude a wide range of structurally dissimilar drugs. Currently, much research is directed toward understanding the molecular mechanisms of these transport proteins. Potential clinical applications include the design of i作者: 組裝 時間: 2025-3-29 22:32
Penicillin-Binding Proteins and β-Lactam Resistanceses or endopeptidases rather than transpeptidases. In the intervening three decades, intense research has been carried out on PBPs, particularly on their role in the resistance to -lactams of some important pathogens such as ., . and ..作者: FLIC 時間: 2025-3-30 00:17
https://doi.org/10.1007/978-981-13-3444-3The acquisition of any type of resistance produces a change. In biology, any change is not only an opportunity, but is also a risk for evolution. Bacterial organisms are highly integrated functional structures, exquisitely tuned by evolutionary forces to fi t with their environments. Beyond the thre作者: impale 時間: 2025-3-30 05:21 作者: 群居動物 時間: 2025-3-30 09:46
https://doi.org/10.1007/978-1-4615-8609-8known to be composed of the replication and transfer functions of the plasmids, and the genes in these studies are now known to be on mobile elements (simple and composite transposons and integrons). The 1960s and 1970s saw a rapid increase in the number of antibiotics (particularly aminoglycosides 作者: musicologist 時間: 2025-3-30 13:46 作者: 是他笨 時間: 2025-3-30 18:29 作者: 金盤是高原 時間: 2025-3-30 23:06
Pressure, Magnetic-Field, and Size Effects,ses or endopeptidases rather than transpeptidases. In the intervening three decades, intense research has been carried out on PBPs, particularly on their role in the resistance to -lactams of some important pathogens such as ., . and ..作者: Adherent 時間: 2025-3-31 02:00 作者: HATCH 時間: 2025-3-31 08:15 作者: 煩人 時間: 2025-3-31 11:02 作者: 刪減 時間: 2025-3-31 13:43 作者: Permanent 時間: 2025-3-31 21:02
Electrical Resistance of Metalstheir strong covalent binding to essential penicillin binding proteins (PBPs) that catalyze the last steps of cell wall formation in both Gram-positive and Gram-negative bacteria (3, 4). However, resistance to these agents has been a major concern to all who use, or have used, βlactams therapeutically.作者: BRACE 時間: 2025-3-31 21:47 作者: 倫理學 時間: 2025-4-1 04:26 作者: 衍生 時間: 2025-4-1 06:12 作者: Rotator-Cuff 時間: 2025-4-1 13:33 作者: 背叛者 時間: 2025-4-1 16:56
1.3.3 References for 1.3.1 and 1.3.2,resistance rates are being noted. This emerging resistance to metronidazole poses various diagnostic and therapeutic dilemmas. Mechanisms of resistance are being defi ned, and a better understanding is the key for prevention of resistance and improved management of these infections.作者: 緩和 時間: 2025-4-1 20:10
