標(biāo)題: Titlebook: Antiepileptic Drug Discovery; Novel Approaches Alan Talevi,Luisa Rocha Book 2016 Springer Science+Business Media New York 2016 Antiepilepto [打印本頁] 作者: ANNOY 時(shí)間: 2025-3-21 18:44
書目名稱Antiepileptic Drug Discovery影響因子(影響力)
書目名稱Antiepileptic Drug Discovery影響因子(影響力)學(xué)科排名
書目名稱Antiepileptic Drug Discovery網(wǎng)絡(luò)公開度
書目名稱Antiepileptic Drug Discovery網(wǎng)絡(luò)公開度學(xué)科排名
書目名稱Antiepileptic Drug Discovery被引頻次
書目名稱Antiepileptic Drug Discovery被引頻次學(xué)科排名
書目名稱Antiepileptic Drug Discovery年度引用
書目名稱Antiepileptic Drug Discovery年度引用學(xué)科排名
書目名稱Antiepileptic Drug Discovery讀者反饋
書目名稱Antiepileptic Drug Discovery讀者反饋學(xué)科排名
作者: 縫紉 時(shí)間: 2025-3-21 20:21 作者: NICE 時(shí)間: 2025-3-22 03:55
Antiepileptic Drug Discovery978-1-4939-6355-3Series ISSN 1557-2153 Series E-ISSN 1940-6053 作者: intricacy 時(shí)間: 2025-3-22 07:04
Angaben aus der Festigkeitslehre,the susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.作者: 詳細(xì)目錄 時(shí)間: 2025-3-22 11:29 作者: eustachian-tube 時(shí)間: 2025-3-22 13:39
Methods in Pharmacology and Toxicologyhttp://image.papertrans.cn/a/image/158539.jpg作者: prosthesis 時(shí)間: 2025-3-22 18:06
,Beziehung zwischen H?rte und Zugfestigkeit,d after seizures in experimental models and, in some cases, still overexpressed later during the chronic stage. Increased levels of these cytokines have been found in the serum from epileptic patients. Pharmacological approaches in rodents support that neuroinflammation is involved in modulating sei作者: Introduction 時(shí)間: 2025-3-23 00:02
Angaben aus der Festigkeitslehre,the susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.作者: 聾子 時(shí)間: 2025-3-23 04:33
Angaben aus der Festigkeitslehre,rly, the design of AEDs based on molecular targets constitutes a promising alternative to empirical screening, the traditional method to detect anticonvulsant action in new structures. In this chapter we described the advances in the dynamic field of carbonic anhydrases, with emphasis in the develop作者: 訓(xùn)誡 時(shí)間: 2025-3-23 08:37
Angaben aus der Festigkeitslehre,xpressed ubiquitously throughout the brain in all nerve terminals independently of their neurotransmitter. It plays an important role in ensuring correct neurotransmission by priming vesicles for fusion. SV2A is the molecular target of the anticonvulsant drug levetiracetam (LEV), whose effects might作者: PET-scan 時(shí)間: 2025-3-23 11:05
,Massive Decken zwischen I-Tr?gern,ids can regulate the expression of epileptic seizures as well as the epileptogenesis process. Some of them suggest that cannabinoids may represent a therapeutic approach for different types of epilepsy. However, experimental evidence indicates that the effects of cannabinoids depend on several exper作者: covert 時(shí)間: 2025-3-23 15:43
https://doi.org/10.1007/978-3-662-25897-2ted that glutamate plays an important role in seizure generation and spread. Glutamate is the predominant excitatory neurotransmitter in the brain, exerting its action through ionotropic and metabotropic receptors. Notably, a significant increase of extracellular glutamate release was observed in hi作者: 就職 時(shí)間: 2025-3-23 19:31
,Angaben für die Berechnung von Tr?gern,tability. Neurosteroids suppress seizures, and this action is particularly important in women with epilepsy, who may experience seizure exacerbation due to hormonal fluctuations associated with their menstrual cycle, called catamenial epilepsy. Neurosteroids exert their anticonvulsant action by incr作者: incredulity 時(shí)間: 2025-3-23 22:28 作者: 安撫 時(shí)間: 2025-3-24 06:23
https://doi.org/10.1007/978-3-662-12947-0lepsy. These are the ketogenic diet, medium-chain triglyceride regime, modified Atkins diet and low glycemic index treatment, all of which have been used clinically. These nutritional procedures are effective and have few adverse collateral actions. A related diet is caloric restriction, which can b作者: 削減 時(shí)間: 2025-3-24 10:34
https://doi.org/10.1007/978-3-662-12947-0e genetic engineering of viruses or plasmids and subsequent transfection into cells that will express transgenes in the central nervous system (CNS) may allow specific treatment in epileptogenic foci while sparing healthy brain tissue, and minimize the side effects of antiepileptic drug treatment. P作者: 施加 時(shí)間: 2025-3-24 11:13
https://doi.org/10.1007/978-3-7091-9787-5itro. We describe three approaches that represent an excellent opportunity for the study of the underlying mechanisms of pharmacoresistant epilepsy: in vitro electrophysiological recordings, in vitro procedures for receptor evaluation, and genomic analyses. These procedures could allow individual di作者: 縱火 時(shí)間: 2025-3-24 16:22 作者: erythema 時(shí)間: 2025-3-24 22:33 作者: Classify 時(shí)間: 2025-3-24 23:26 作者: Rct393 時(shí)間: 2025-3-25 07:13
The Use of Anti-inflammatory Drugs in Epilepsythe susceptibility to epileptic activity. Therefore, the search of pharmacological strategies focused on decreasing both neuroinflammation and neuronal excitability associated with epilepsy is important. This chapter is a review of several drugs that may be used for this purpose.作者: 彩色的蠟筆 時(shí)間: 2025-3-25 10:22
Inflammatory Cytokines as Targets for Epilepsy Drug Therapyd after seizures in experimental models and, in some cases, still overexpressed later during the chronic stage. Increased levels of these cytokines have been found in the serum from epileptic patients. Pharmacological approaches in rodents support that neuroinflammation is involved in modulating sei作者: RAGE 時(shí)間: 2025-3-25 11:46 作者: misanthrope 時(shí)間: 2025-3-25 18:02 作者: 帶子 時(shí)間: 2025-3-26 00:01
Synaptic Vesicle Protein 2A as a Novel Pharmacological Target with Broad Potential for New Antiepilexpressed ubiquitously throughout the brain in all nerve terminals independently of their neurotransmitter. It plays an important role in ensuring correct neurotransmission by priming vesicles for fusion. SV2A is the molecular target of the anticonvulsant drug levetiracetam (LEV), whose effects might作者: Kidnap 時(shí)間: 2025-3-26 00:35
Do Cannabinoids Represent a Good Therapeutic Strategy for Epilepsy?ids can regulate the expression of epileptic seizures as well as the epileptogenesis process. Some of them suggest that cannabinoids may represent a therapeutic approach for different types of epilepsy. However, experimental evidence indicates that the effects of cannabinoids depend on several exper作者: 絆住 時(shí)間: 2025-3-26 04:42
Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapyted that glutamate plays an important role in seizure generation and spread. Glutamate is the predominant excitatory neurotransmitter in the brain, exerting its action through ionotropic and metabotropic receptors. Notably, a significant increase of extracellular glutamate release was observed in hi作者: RAGE 時(shí)間: 2025-3-26 09:05
Neurosteroid Regulation of Seizures: Role of GABAA Receptor Plasticitytability. Neurosteroids suppress seizures, and this action is particularly important in women with epilepsy, who may experience seizure exacerbation due to hormonal fluctuations associated with their menstrual cycle, called catamenial epilepsy. Neurosteroids exert their anticonvulsant action by incr作者: 權(quán)宜之計(jì) 時(shí)間: 2025-3-26 14:24
Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Etivation of both receptor to EPO (EPO-R), which undergoes a classic dimeric conformation called (EPO-R)., and the EPOR-β common receptor (βCR). The interaction between EPO and EPO-R can prevent and repair tissue damage induced by hypoxia and neuroinflammation. The current chapter is focused on prese作者: 誘使 時(shí)間: 2025-3-26 18:48 作者: Interlocking 時(shí)間: 2025-3-26 22:28 作者: 震驚 時(shí)間: 2025-3-27 01:07 作者: 植物茂盛 時(shí)間: 2025-3-27 05:37 作者: capsaicin 時(shí)間: 2025-3-27 09:38 作者: 品嘗你的人 時(shí)間: 2025-3-27 15:17 作者: Palate 時(shí)間: 2025-3-27 19:47
The Blood–Brain Barrier and the Design of New Antiepileptic Drugs作者: 防水 時(shí)間: 2025-3-27 23:01 作者: JADED 時(shí)間: 2025-3-28 03:40
Synaptic Vesicle Protein 2A as a Novel Pharmacological Target with Broad Potential for New Antiepileof the role of SV2A in epilepsy, addressing three main issues: SV2A function in neurotransmission, the correlation of the expression and/or distribution of the protein with treatment response and neuronal damage, and the reasons that SV2A is a good molecular target for the discovery of new antiepile作者: entice 時(shí)間: 2025-3-28 06:25
Glutamate Receptors as Targets for Novel Antiepileptic Drug Therapyharmacological blockade of glutamatergic signaling represents an attractive alternative for the control of seizures and neuroprotection. In particular, glutamate receptors are attractive targets for novel antiepileptic drugs because different studies have demonstrated that its agonists and antagonis作者: chronicle 時(shí)間: 2025-3-28 12:33 作者: jaundiced 時(shí)間: 2025-3-28 14:58
Erythropoietin as Potential Neuroprotective and Antiepileptogenic Agent in Epilepsy and Refractory Egh doses of EPO could also reduce the brain damage that results from seizure activity seen in the epileptogenic process subsequent to status epilepticus and perhaps avoids sudden unexpected death in epilepsy (SUDEP).作者: 亂砍 時(shí)間: 2025-3-28 19:26
Caloric Restriction and Dietary Treatments of Epilepsy: Mechanistic Insights for Drug Discoveryalthough several possibilities have been suggested. Each of its proposed mechanisms of action can be targeted for the discovery of drugs that prevent or modify epilepsy. This chapter briefly describes every one of the food modifications in current clinical use or that has been studied using animal m作者: mitten 時(shí)間: 2025-3-29 00:58
Gene Therapy in Epilepsywhich exerts neuroprotective and anticonvulsive actions. Recombinant adeno-associated viral vectors can release any of these agents because of their neuronal tropism, lack of toxicity, and stable persistence in neurons. This chapter provides an overview of gene therapy methods, and reviews several s作者: MIME 時(shí)間: 2025-3-29 04:17 作者: 報(bào)復(fù) 時(shí)間: 2025-3-29 07:30
Nanoformulations of Antiepileptic Drugs: In Vitro and In Vivo Studiesed situation is far beyond the possibilities of the present book chapter, and the sanitary problem of epilepsy (as well as other CNS diseases treated with anticonvulsant drugs) has already been described in the previous chapters. Hence, we will focus in the pharmacokinetic aspects of the problem of 作者: Bother 時(shí)間: 2025-3-29 14:29
Angaben aus der Festigkeitslehre,of the role of SV2A in epilepsy, addressing three main issues: SV2A function in neurotransmission, the correlation of the expression and/or distribution of the protein with treatment response and neuronal damage, and the reasons that SV2A is a good molecular target for the discovery of new antiepile作者: 共和國 時(shí)間: 2025-3-29 16:21
https://doi.org/10.1007/978-3-662-25897-2harmacological blockade of glutamatergic signaling represents an attractive alternative for the control of seizures and neuroprotection. In particular, glutamate receptors are attractive targets for novel antiepileptic drugs because different studies have demonstrated that its agonists and antagonis作者: placebo-effect 時(shí)間: 2025-3-29 21:18 作者: 晚間 時(shí)間: 2025-3-30 00:34
Angaben aus der Festigkeitslehre,gh doses of EPO could also reduce the brain damage that results from seizure activity seen in the epileptogenic process subsequent to status epilepticus and perhaps avoids sudden unexpected death in epilepsy (SUDEP).作者: 商議 時(shí)間: 2025-3-30 05:03
https://doi.org/10.1007/978-3-662-12947-0although several possibilities have been suggested. Each of its proposed mechanisms of action can be targeted for the discovery of drugs that prevent or modify epilepsy. This chapter briefly describes every one of the food modifications in current clinical use or that has been studied using animal m作者: pacifist 時(shí)間: 2025-3-30 10:21 作者: VEST 時(shí)間: 2025-3-30 13:58 作者: 直言不諱 時(shí)間: 2025-3-30 19:55 作者: 口音在加重 時(shí)間: 2025-3-30 20:52 作者: 有罪 時(shí)間: 2025-3-31 04:43
